Adam Burgener

Summary

Affiliation: University of Manitoba
Country: Canada

Publications

  1. pmc A systems biology examination of the human female genital tract shows compartmentalization of immune factor expression
    Adam Burgener
    University of Manitoba, Department of Medical Microbiology, Winnipeg, Manitoba, Canada
    J Virol 87:5141-50. 2013
  2. ncbi Salivary basic proline-rich proteins are elevated in HIV-exposed seronegative men who have sex with men
    Adam Burgener
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada
    AIDS 26:1857-67. 2012
  3. doi Comprehensive proteomic study identifies serpin and cystatin antiproteases as novel correlates of HIV-1 resistance in the cervicovaginal mucosa of female sex workers
    A Burgener
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada
    J Proteome Res 10:5139-49. 2011
  4. doi Identification of differentially expressed proteins in the cervical mucosa of HIV-1-resistant sex workers
    Adam Burgener
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada R3T 2N2
    J Proteome Res 7:4446-54. 2008
  5. doi Mucosal serpin A1 and A3 levels in HIV highly exposed sero-negative women are affected by the menstrual cycle and hormonal contraceptives but are independent of epidemiological confounders
    Syeda Rahman
    Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada
    Am J Reprod Immunol 69:64-72. 2013
  6. pmc Unbiased proteomics analysis demonstrates significant variability in mucosal immune factor expression depending on the site and method of collection
    Kenzie M Birse
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada Proteomics Group, National Lab for HIV Immunology, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
    PLoS ONE 8:e79505. 2013
  7. doi Proteomics as a novel HIV immune monitoring tool
    Derek R Stein
    University of Manitoba, Department of Medical Microbiology bImmunology, Winnipeg, Manitoba, Canada
    Curr Opin HIV AIDS 8:140-6. 2013
  8. doi The role of serpin and cystatin antiproteases in mucosal innate immunity and their defense against HIV
    Lindsay Aboud
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada
    Am J Reprod Immunol 71:12-23. 2014
  9. doi Profiling cervical lavage fluid by SELDI-TOF mass spectrometry
    Adam Burgener
    National Laboratory for HIV Immunology, Public Health Agency of Canada, Winnipeg, MB, Canada
    Methods Mol Biol 818:143-52. 2012
  10. doi Systems biology-based approaches to understand HIV-exposed uninfected women
    Adam Burgener
    National Laboratory for HIV Immunology, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, Manitoba, Canada
    Curr HIV/AIDS Rep 7:53-9. 2010

Collaborators

Detail Information

Publications10

  1. pmc A systems biology examination of the human female genital tract shows compartmentalization of immune factor expression
    Adam Burgener
    University of Manitoba, Department of Medical Microbiology, Winnipeg, Manitoba, Canada
    J Virol 87:5141-50. 2013
    ..This may have important implications for early events in HIV transmission and site-specific susceptibility to HIV in the FGT...
  2. ncbi Salivary basic proline-rich proteins are elevated in HIV-exposed seronegative men who have sex with men
    Adam Burgener
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada
    AIDS 26:1857-67. 2012
    ..We performed proteomic analysis of saliva from a cohort of HESN MSM who have regular unprotected oral receptive intercourse with their HIV-infected partner...
  3. doi Comprehensive proteomic study identifies serpin and cystatin antiproteases as novel correlates of HIV-1 resistance in the cervicovaginal mucosa of female sex workers
    A Burgener
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada
    J Proteome Res 10:5139-49. 2011
    ..This comprehensive systems biology approach identifies mucosal serpins and cystatins as novel correlates of HIV-1-resistance. This represents the first study characterizing these factors in the female genital tract...
  4. doi Identification of differentially expressed proteins in the cervical mucosa of HIV-1-resistant sex workers
    Adam Burgener
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada R3T 2N2
    J Proteome Res 7:4446-54. 2008
    ..Validation of these results on a larger sample of individuals will provide further evidence these biomarkers are associated with HIV-1 resistance and could help aid in the development of effective microbicides against HIV-1...
  5. doi Mucosal serpin A1 and A3 levels in HIV highly exposed sero-negative women are affected by the menstrual cycle and hormonal contraceptives but are independent of epidemiological confounders
    Syeda Rahman
    Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada
    Am J Reprod Immunol 69:64-72. 2013
    ..Here, we characterized mucosal serpin expression in the genital tract of HIV highly exposed sero-negative (HESN) women meeting our epidemiological definition of HIV resistance in relation to epidemiological variables...
  6. pmc Unbiased proteomics analysis demonstrates significant variability in mucosal immune factor expression depending on the site and method of collection
    Kenzie M Birse
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada Proteomics Group, National Lab for HIV Immunology, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
    PLoS ONE 8:e79505. 2013
    ....
  7. doi Proteomics as a novel HIV immune monitoring tool
    Derek R Stein
    University of Manitoba, Department of Medical Microbiology bImmunology, Winnipeg, Manitoba, Canada
    Curr Opin HIV AIDS 8:140-6. 2013
    ....
  8. doi The role of serpin and cystatin antiproteases in mucosal innate immunity and their defense against HIV
    Lindsay Aboud
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada
    Am J Reprod Immunol 71:12-23. 2014
    ..Their potential as therapeutic interventions to combat HIV is also discussed...
  9. doi Profiling cervical lavage fluid by SELDI-TOF mass spectrometry
    Adam Burgener
    National Laboratory for HIV Immunology, Public Health Agency of Canada, Winnipeg, MB, Canada
    Methods Mol Biol 818:143-52. 2012
    ..This chapter will outline detailed methods to profile cervical mucosal samples by SELDI-TOF and can serve as a guideline for other types of mucosal samples...
  10. doi Systems biology-based approaches to understand HIV-exposed uninfected women
    Adam Burgener
    National Laboratory for HIV Immunology, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, Manitoba, Canada
    Curr HIV/AIDS Rep 7:53-9. 2010
    ..Herein we report developments in discovery-based systems biology approaches in EU women and how this broadens our understanding of natural protection against HIV-1...