R C Bray

Summary

Affiliation: University of Calgary
Country: Canada

Publications

  1. ncbi request reprint Vascular response of the meniscus to injury: effects of immobilization
    R C Bray
    McCaig Centre for Joint Injury and Arthritis Research, Department of Surgery, University of Calgary, Alberta, Canada
    J Orthop Res 19:384-90. 2001
  2. ncbi request reprint Vascular physiology and long-term healing of partial ligament tears
    Robert C Bray
    Department of Surgery, McCaig Centre for Joint Injury and Arthritis Research, University of Calgary, Alta, Canada
    J Orthop Res 20:984-9. 2002
  3. ncbi request reprint Laser Doppler imaging of burn scars: a comparison of wavelength and scanning methods
    Robert Bray
    Department of Surgery, McCaig Center for Joint Injury and Arthritis Research, 3330 Hospital Dr NW, University of Calgary, Calgary, Alta, Canada
    Burns 29:199-206. 2003
  4. ncbi request reprint Correlation of healing capacity with vascular response in the anterior cruciate and medial collateral ligaments of the rabbit
    Robert C Bray
    Department of Surgery, University of Calgary, 3330 Hospital Drive NW, Alta T2N 4N1, Calgary, Canada
    J Orthop Res 21:1118-23. 2003
  5. ncbi request reprint Endoscopic laser speckle imaging of tissue blood flow: applications in the human knee
    R C Bray
    McCaig Centre for Joint Injury and Arthritis Research, Department of Surgery, University of Calgary, Calgary, Alberta, Canada T2N 4N1
    J Orthop Res 24:1650-9. 2006
  6. ncbi request reprint Vascular adaptation of intact joint stabilizing structures in the posterior cruciate ligament deficient rabbit knee
    Robert C Bray
    McCaig Centre for Joint Injury and Arthritis Research, Department of Surgery, University of Calgary, 3330 Hospital Drive NW, Calgary, Alta, Canada T2N 4N1
    J Orthop Res 21:787-91. 2003
  7. ncbi request reprint Physiological and mechanical adaptations of rabbit medial collateral ligament after anterior cruciate ligament transection
    R C Bray
    McCaig Centre for Joint Injury and Arthritis Research, Faculty of Medicine, University of Calgary, Alberta, Canada
    J Orthop Res 15:830-6. 1997
  8. ncbi request reprint Comparison of laser speckle and laser Doppler perfusion imaging: measurement in human skin and rabbit articular tissue
    K R Forrester
    Department of Medical Science, Biomedical Engineering Program, University of Calgary, Calgary, Canada
    Med Biol Eng Comput 40:687-97. 2002
  9. ncbi request reprint Endoscopic laser imaging of tissue perfusion: new instrumentation and technique
    K R Forrester
    McCaig Centre for Joint Injury and Arthritis Research, Department of Surgery, University of Calgary, Calgary, Alberta, Canada T2N 4N1
    Lasers Surg Med 33:151-7. 2003
  10. ncbi request reprint A comparison of two laser-based methods for determination of burn scar perfusion: laser Doppler versus laser speckle imaging
    C J Stewart
    McCaig Centre for Joint Injury and Arthritis Research, Department of Surgery, University of Calgary, 3330 Hospital Drive NW, Calgary, Alta, Canada T2N 4N1
    Burns 31:744-52. 2005

Detail Information

Publications27

  1. ncbi request reprint Vascular response of the meniscus to injury: effects of immobilization
    R C Bray
    McCaig Centre for Joint Injury and Arthritis Research, Department of Surgery, University of Calgary, Alberta, Canada
    J Orthop Res 19:384-90. 2001
    ..Characterization of the vascular responses to meniscal injury may lead to techniques that can promote reliable healing of meniscal tears and thereby improve clinical outcomes...
  2. ncbi request reprint Vascular physiology and long-term healing of partial ligament tears
    Robert C Bray
    Department of Surgery, McCaig Centre for Joint Injury and Arthritis Research, University of Calgary, Alta, Canada
    J Orthop Res 20:984-9. 2002
    ..Although both MCL and ACL showed increased weight after PCL transection, the lack of a long-term vascular response in the ACL may be a major factor in its the diminished healing potential...
  3. ncbi request reprint Laser Doppler imaging of burn scars: a comparison of wavelength and scanning methods
    Robert Bray
    Department of Surgery, McCaig Center for Joint Injury and Arthritis Research, 3330 Hospital Dr NW, University of Calgary, Calgary, Alta, Canada
    Burns 29:199-206. 2003
    ..We have evaluated two commercially available laser Doppler imagers for the perfusion measurement of normal and burn scar tissue...
  4. ncbi request reprint Correlation of healing capacity with vascular response in the anterior cruciate and medial collateral ligaments of the rabbit
    Robert C Bray
    Department of Surgery, University of Calgary, 3330 Hospital Drive NW, Alta T2N 4N1, Calgary, Canada
    J Orthop Res 21:1118-23. 2003
    ..The superior capacity of the MCL to increase its blood supply through angiogenesis and increased flow is essential for ligament healing to occur, and may be the major difference in healing potential between the ACL and MCL...
  5. ncbi request reprint Endoscopic laser speckle imaging of tissue blood flow: applications in the human knee
    R C Bray
    McCaig Centre for Joint Injury and Arthritis Research, Department of Surgery, University of Calgary, Calgary, Alberta, Canada T2N 4N1
    J Orthop Res 24:1650-9. 2006
    ..These are the first in vivo results indicating physiologic changes in articular tissue as a function of two commonly applied practices in endoscopic joint surgery...
  6. ncbi request reprint Vascular adaptation of intact joint stabilizing structures in the posterior cruciate ligament deficient rabbit knee
    Robert C Bray
    McCaig Centre for Joint Injury and Arthritis Research, Department of Surgery, University of Calgary, 3330 Hospital Drive NW, Calgary, Alta, Canada T2N 4N1
    J Orthop Res 21:787-91. 2003
    ..Changes in wet weight and water content of both the MCL and ACL demonstrate prolonged physiological adaptation of intact structures in lax joints...
  7. ncbi request reprint Physiological and mechanical adaptations of rabbit medial collateral ligament after anterior cruciate ligament transection
    R C Bray
    McCaig Centre for Joint Injury and Arthritis Research, Faculty of Medicine, University of Calgary, Alberta, Canada
    J Orthop Res 15:830-6. 1997
    ....
  8. ncbi request reprint Comparison of laser speckle and laser Doppler perfusion imaging: measurement in human skin and rabbit articular tissue
    K R Forrester
    Department of Medical Science, Biomedical Engineering Program, University of Calgary, Calgary, Canada
    Med Biol Eng Comput 40:687-97. 2002
    ..This in vivo study demonstrated some of the several advantages laser speckle imaging has over conventional LDI, making the new instrument more versatile in a clinical environment...
  9. ncbi request reprint Endoscopic laser imaging of tissue perfusion: new instrumentation and technique
    K R Forrester
    McCaig Centre for Joint Injury and Arthritis Research, Department of Surgery, University of Calgary, Calgary, Alberta, Canada T2N 4N1
    Lasers Surg Med 33:151-7. 2003
    ..New instrumentation, based on a previously established laser speckle perfusion imaging (LSI) technique is evaluated for its ability to capture and generate blood flow images during endoscopic surgery...
  10. ncbi request reprint A comparison of two laser-based methods for determination of burn scar perfusion: laser Doppler versus laser speckle imaging
    C J Stewart
    McCaig Centre for Joint Injury and Arthritis Research, Department of Surgery, University of Calgary, 3330 Hospital Drive NW, Calgary, Alta, Canada T2N 4N1
    Burns 31:744-52. 2005
    ..We have evaluated the ability of the LSPI instrument in determining and monitoring burn scar perfusion over time and compared it with the LDI instrument as a standard...
  11. ncbi request reprint Bisphosphonates reduce bone mineral loss at ligament entheses after joint injury
    M R Doschak
    McCaig Centre for Joint Injury and Arthritis Research, Biomedical Peptide Conjunction Laboratory, Department of Chemical and Materials Engineering, University of Calgary, Calgary, AB, Canada
    Osteoarthritis Cartilage 13:790-7. 2005
    ..To examine the effects of anterior cruciate ligament (ACL) insufficiency, and subsequent bisphosphonate (BP) antiresorptive therapy, on the bone mineral interface at the enthesis of remaining ligamentous restraints...
  12. pmc Vascular alterations in the rabbit patellar tendon after surgical incision
    M R Doschak
    McCaig Centre for Joint Injury and Arthritis Research, Department of Surgery, Faculty of Medicine, University of Calgary, Alberta, Canada
    J Anat 198:513-23. 2001
    ....
  13. ncbi request reprint Neurogenic origin of articular hyperemia in early degenerative joint disease
    J J McDougall
    McCaig Centre for Joint Injury and Arthritis Research, Department of Surgery, University of Calgary, Calgary, Alberta, Canada T2N 4N1
    Am J Physiol 276:R745-52. 1999
    ..By contrast, nerve-mediated constrictor responses were mostly unaffected by joint instability. This study suggests that posttraumatic knee joint hyperemia is neurogenically mediated, possibly by increased secretion of CGRP...
  14. ncbi request reprint Kinetics of blood flow during healing of excisional full-thickness skin wounds in pigs as monitored by laser speckle perfusion imaging
    C J Stewart
    Department of Surgery, McCaig Centre for Joint Injury and Arthritis Research, University of Calgary, Calgary, AB, Canada
    Skin Res Technol 12:247-53. 2006
    ..The present study investigates the ability of the LSPI system to detect temporal changes in blood flow during the healing of cutaneous wounds in a well-characterized animal model...
  15. ncbi request reprint Vascular volume determination of articular tissues in normal and anterior cruciate ligament-deficient rabbit knees
    J J McDougall
    McCaig Center for Joint Injury and Arthritis Research, Department of Surgery, University of Calgary, Alberta, Canada
    Anat Rec 251:207-13. 1998
    ..Joint instability stimulates angiogenesis in the ipsilateral MCL; however, the absence of angiogenic activity in other articular tissues might help explain the lack of posttraumatic healing associated with these joints...
  16. ncbi request reprint Adaptation of post-traumatic angiogenesis in the rabbit knee by apposition of torn ligament ends
    J J McDougall
    McCaig Centre for Joint Injury and Arthritis Research, University of Calgary, Alberta, Canada
    J Orthop Res 18:663-70. 2000
    ..Furthermore, apposition of an injured medial collateral ligament modifies these pro-angiogenic events, and this may partly explain why contact of torn ligament ends is beneficial for post-traumatic recovery of an injured joint...
  17. ncbi request reprint Evaluation of laser-Doppler perfusion imaging for measurement of blood flow in cortical bone
    R C Shymkiw
    McCaig Centre for Joint Injury and Arthritis Research, University of Calgary, Calgary, Alberta, Canada T2N 4N1
    J Appl Physiol 90:1314-8. 2001
    ..05). Repeatability of consecutive LDI measurements was within 5%. The effectiveness of LDI to measure perfusion in bone suggests this method has potential for investigating the role of blood flow in bone metabolism and remodeling...
  18. pmc Spatial variation in sympathetic influences on the vasculature of the synovium and medial collateral ligament of the rabbit knee joint
    J J McDougall
    McCaig Centre for Joint Injury and Arthritis Research, Department of Surgery, University of Calgary, Canada
    J Physiol 503:435-43. 1997
    ..Neuromodulation of ligament perfusion appears to predominate at the femoral insertion and this could prove to have functional significance...
  19. ncbi request reprint Denervation impairs healing of the rabbit medial collateral ligament
    T J Ivie
    McCaig Centre for Joint Injury and Arthritis Research, Faculty of Medicine, University of Calgary, AB, Canada
    J Orthop Res 20:990-5. 2002
    ..29 +/- 0.62% compared to 3.64 +/- 0.31% in innervated MCL's (p < 0.05). We conclude that intact innervation makes a critical contribution to the early healing responses of the MCL of adult rabbits...
  20. ncbi request reprint A role for calcitonin gene-related peptide in rabbit knee joint ligament healing
    J J McDougall
    McCaig Centre for Joint Injury and Arthritis Research, University of Calgary, AB, Canada
    Can J Physiol Pharmacol 78:535-40. 2000
    ..Conversely, the aberrant characteristics of CGRP-LI nerves occurring in gap injured tissue is suggestive of impaired CGRP release which may explain the poor functional recovery associated with these ligaments...
  21. ncbi request reprint Antiresorptive therapy conserves some periarticular bone and ligament mechanical properties after anterior cruciate ligament disruption in the rabbit knee
    M R Doschak
    Department of Surgery, University of Calgary, 3330 Hospital Drive N W, Calgary, Alberta, Canada T2N 4N1
    J Orthop Res 22:942-8. 2004
    ..Thus, administering BP immediately after ACL loss conserved some periarticular bone and MCL-complex properties in an early OA model...
  22. ncbi request reprint Late gestational changes in sympathomimetic sensitivity in primagravid rabbit ligaments
    J J McDougall
    McCaig Centre for Joint Injury and Arthritis Research, University of Calgary, AB, Canada
    Can J Physiol Pharmacol 78:528-34. 2000
    ..Pregnancy leads to either downregulation and (or) desensitisation of alpha1 and beta2-adrenoceptors in the ligament which could disrupt normal joint homeostasis...
  23. ncbi request reprint Bone hyperemia precedes disuse-induced intracortical bone resorption
    T S Gross
    McCaig Centre for Joint Injury and Arthritis Research, Department of Surgery, University of Calgary, Calgary, Canada T2N 4N1
    J Appl Physiol 86:230-5. 1999
    ..02 vs. 0. 002 +/- 0.002 mm2; P = 0.03). We conclude that disuse induces bone hyperemia before an increase in intracortical porosity. The potential interaction between bone vasoregulation and bone cell dynamics remains to be studied...
  24. ncbi request reprint Cholinergic vasoregulation in normal and adjuvant monoarthritic rat knee joints
    J J McDougall
    McCaig Centre for Joint Injury and Arthritis Research, Department of Surgery, University of Calgary, Alberta, Canada
    J Auton Nerv Syst 72:55-60. 1998
    ..Furthermore, the preservation of cholinergic responses in the contralateral knee despite a fall in basal perfusion suggests that alternative non-cholinergic mechanisms may be responsible for the hypoaemia in this joint...
  25. doi request reprint A transmissive laser speckle imaging technique for measuring deep tissue blood flow: an example application in finger joints
    J F Dunn
    Department of Radiology and Experimental Imaging Centre, University of Calgary, Calgary, Alberta, Canada
    Lasers Surg Med 43:21-8. 2011
    ..Captured light then travels the entire tissue thickness (10-15 mm), sampling much deeper regions of interest than conventional optical imaging techniques...
  26. ncbi request reprint Neuropeptides regulate expression of matrix molecule, growth factor and inflammatory mediator mRNA in explants of normal and healing medial collateral ligament
    Paul Salo
    Department of Surgery, University of Calgary, Calgary, Alberta, Canada
    Regul Pept 142:1-6. 2007
    ..The results indicate that neuropeptides strongly influence the metabolic activity of cells in healing ligament, particularly at early time points after injury...
  27. pmc Angiogenesis in the distal femoral chondroepiphysis of the rabbit during development of the secondary centre of ossification
    M R Doschak
    Department of Surgery, McCaig Centre for Joint Injury and Arthritis Research, Faculty of Medicine, University of Calgary, Alberta, Canada
    J Anat 203:223-33. 2003
    ..Furthermore, the discovery of angiogenic, angiostatic or mineral-regulating mediators specific to developing connective tissue may prove useful for analysing the regulation of vascular and mineral pathogenesis in articular tissues...