Arend Bonen

Summary

Affiliation: University of Guelph
Country: Canada

Publications

  1. Bonen A. PGC-1alpha-induced improvements in skeletal muscle metabolism and insulin sensitivity. Appl Physiol Nutr Metab. 2009;34:307-14 pubmed publisher
    ....
  2. request reprint
    Bonen A, Han X, Habets D, Febbraio M, Glatz J, Luiken J. A null mutation in skeletal muscle FAT/CD36 reveals its essential role in insulin- and AICAR-stimulated fatty acid metabolism. Am J Physiol Endocrinol Metab. 2007;292:E1740-9 pubmed
    ..7-fold greater in WT compared with KO mice. In conclusion, the present studies demonstrate that FAT/CD36 has a critical role in regulating fatty acid esterification and oxidation, particularly during stimulation with insulin or AICAR. ..
  3. Benton C, Holloway G, Campbell S, Yoshida Y, Tandon N, Glatz J, et al. Rosiglitazone increases fatty acid oxidation and fatty acid translocase (FAT/CD36) but not carnitine palmitoyltransferase I in rat muscle mitochondria. J Physiol. 2008;586:1755-66 pubmed publisher
    ..Moreover, these studies identify for the first time a mechanism by which rosiglitazone stimulates fatty acid oxidation in skeletal muscle, namely the chronic, subcellular relocation of FAT/CD36 to mitochondria...
  4. Bonen A, Holloway G, Tandon N, Han X, McFarlan J, Glatz J, et al. Cardiac and skeletal muscle fatty acid transport and transporters and triacylglycerol and fatty acid oxidation in lean and Zucker diabetic fatty rats. Am J Physiol Regul Integr Comp Physiol. 2009;297:R1202-12 pubmed publisher
    ..Upregulation of fatty acid transport increased red muscle, but not cardiac, triacylglycerol accumulation. White muscle lipid metabolism dysregulation was not observed...

Locale

Detail Information

Publications4

  1. Bonen A. PGC-1alpha-induced improvements in skeletal muscle metabolism and insulin sensitivity. Appl Physiol Nutr Metab. 2009;34:307-14 pubmed publisher
    ....
  2. request reprint
    Bonen A, Han X, Habets D, Febbraio M, Glatz J, Luiken J. A null mutation in skeletal muscle FAT/CD36 reveals its essential role in insulin- and AICAR-stimulated fatty acid metabolism. Am J Physiol Endocrinol Metab. 2007;292:E1740-9 pubmed
    ..7-fold greater in WT compared with KO mice. In conclusion, the present studies demonstrate that FAT/CD36 has a critical role in regulating fatty acid esterification and oxidation, particularly during stimulation with insulin or AICAR. ..
  3. Benton C, Holloway G, Campbell S, Yoshida Y, Tandon N, Glatz J, et al. Rosiglitazone increases fatty acid oxidation and fatty acid translocase (FAT/CD36) but not carnitine palmitoyltransferase I in rat muscle mitochondria. J Physiol. 2008;586:1755-66 pubmed publisher
    ..Moreover, these studies identify for the first time a mechanism by which rosiglitazone stimulates fatty acid oxidation in skeletal muscle, namely the chronic, subcellular relocation of FAT/CD36 to mitochondria...
  4. Bonen A, Holloway G, Tandon N, Han X, McFarlan J, Glatz J, et al. Cardiac and skeletal muscle fatty acid transport and transporters and triacylglycerol and fatty acid oxidation in lean and Zucker diabetic fatty rats. Am J Physiol Regul Integr Comp Physiol. 2009;297:R1202-12 pubmed publisher
    ..Upregulation of fatty acid transport increased red muscle, but not cardiac, triacylglycerol accumulation. White muscle lipid metabolism dysregulation was not observed...