Research Topics
Species | C BombardierSummaryAffiliation: University of Toronto Country: Canada Publications
| Collaborators
|
Detail Information
Publications
Canadian Rheumatology Association recommendations for the pharmacological management of rheumatoid arthritis with traditional and biologic disease-modifying antirheumatic drugs: part II safetyClaire Bombardier
The Rebecca MacDonald Centre for Arthritis and Autoimmune Disease, Mount Sinai Hospital, Toronto, Canada
J Rheumatol 39:1583-602. 2012..Part II, focusing on specific safety aspects of treatment with traditional and biologic DMARD in patients with RA, is reported here...
Minimal clinically important difference. Low back pain: outcome measuresC Bombardier
Institute for Work and Health, Department of Medicine, University of Toronto, Ontario, Canada
J Rheumatol 28:431-8. 2001..Choosing any value larger than 5 in designing a clinical trial would risk underpowering the trial, since fewer patients are needed if a trial is designed on the basis of a large change score...
An evidence-based evaluation of the gastrointestinal safety of coxibsClaire Bombardier
Division of Clinical Decision Making and Health Care, Toronto General Research Institute, Toronto General Hospital, Toronto, Ontario, Canada
Am J Cardiol 89:3D-9D. 2002..In contrast, the CLASS trial showed that the incidence of ulcer complications in patients treated with celecoxib was similar in patients treated with nonspecific NSAIDs...
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study GroupC Bombardier
Institute for Work and Health, Mount Sinai Hospital, and The University Health Network, Toronto, ON, Canada
N Engl J Med 343:1520-8, 2 p following 1528. 2000....
How Canadian and US rheumatologists treat moderate or aggressive rheumatoid arthritis: a surveyA Maetzel
Healthcare Research Division, Arthritis and Immune Disorder Research Centre, Toronto, Ontario, Canada
J Rheumatol 25:2331-8. 1998..To determine which second line agents Canadian and US rheumatologists use to treat patients with active rheumatoid arthritis (RA)...
Biomechanical and psychosocial risk factors for low back pain at workM S Kerr
Institute for Work and Health, Department of Public Health Sciences, University of Toronto, Ontario, M4W 1E6, Canada
Am J Public Health 91:1069-75. 2001..This study determined whether the physical and psychosocial demands of work are associated with low back pain...
Measuring the whole or the parts? Validity, reliability, and responsiveness of the Disabilities of the Arm, Shoulder and Hand outcome measure in different regions of the upper extremityD E Beaton
Institute for Work and Health Toronto, Ontario, Canada
J Hand Ther 14:128-46. 2001..The Disabilities of the Arm, Shoulder and Hand (DASH) outcome measure was developed to evaluate disability and symptoms in single or multiple disorders of the upper limb at one point or at many points in time...
Use of grade membership analysis to profile the practice styles of individual physicians in the management of acute low back painA Maetzel
Institute for Work and Health, Toronto, Ontario, Canada
J Clin Epidemiol 53:195-205. 2000..GoM is data driven and less subject to judgment than opinion-based measures of performance. It has several potential applications in identifying physicians for whom some form of intervention would be beneficial...
Physician enthusiasm as an explanation for area variation in the utilization of knee replacement surgeryJ G Wright
Department of Surgery and Public Health Sciences, Hospital for Sick Children, University of Toronto, Ontario, Canada
Med Care 37:946-56. 1999..Explanations for regional variation in the use of many medical and surgical treatments is controversial...
Recommendations for the appropriate use of anti-inflammatory drugs in the era of the coxibs: defining the role of gastroprotective agentsRichard H Hunt
Division of Gastroenterology, Department of Medicine, McMaster University Medical Centre, Hamilton, Ontario
Can J Gastroenterol 16:231-40. 2002..Patients at high risk require a GPA in addition to a coxib...
Looking for important change/differences in studies of responsiveness. OMERACT MCID Working Group. Outcome Measures in Rheumatology. Minimal Clinically Important DifferenceD E Beaton
Institute for Work and Health, Department of Occupational Therapy, University of Toronto, Canada
J Rheumatol 28:400-5. 2001..The cube has been shown here as a means to separate out studies that address important change. These studies can then be examined as the source of information on MCID...
Systematic reviews of low back pain prognosis had variable methods and results: guidance for future prognosis reviewsJ A Hayden
Centre of Research Expertise in Improved Disability Outcomes CREIDO, University Health Network, Toronto, Ontario, Canada
J Clin Epidemiol 62:781-796.e1. 2009..The objective of this study was to identify, describe, and synthesize systematic reviews of low back pain prognosis, and explore the potential impact of review methods on the conclusions...
A critical review of reviews on the treatment of chronic low back painA D Furlan
Institute for Work and Health, Toronto, Canada
Spine (Phila Pa 1976) 26:E155-62. 2001..Systematic literature review...
The economic burden associated with osteoarthritis, rheumatoid arthritis, and hypertension: a comparative studyA Maetzel
Division of Clinical Decision Making and Health Care Research, University Health Network Research Institute, Toronto, Ontario, Canada
Ann Rheum Dis 63:395-401. 2004..To compare the economic burden to society incurred by patients with RA, OA, or high blood pressure (HBP) in Ontario, Canada...
Predictors for remission in rheumatoid arthritis patients: A systematic reviewWanruchada Katchamart
University of Toronto, Ontario, Canada
Arthritis Care Res (Hoboken) 62:1128-43. 2010..To summarize the potential predictors of remission in patients with rheumatoid arthritis (RA)...
Cost effectiveness of adding leflunomide to a 5-year strategy of conventional disease-modifying antirheumatic drugs in patients with rheumatoid arthritisAndreas Maetzel
University Health Network Research Institute, Toronto, Ontario, Canada
Arthritis Rheum 47:655-61. 2002....
Herbal medicine for low back pain: a Cochrane reviewJoel J Gagnier
Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Spine (Phila Pa 1976) 32:82-92. 2007..A systematic review of randomized controlled trials...
Recommendations for reporting randomized controlled trials of herbal interventions: Explanation and elaborationJoel J Gagnier
Department of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
J Clin Epidemiol 59:1134-49. 2006..These recommendations for the reporting of herbal medicinal products presented here are open to revision as more evidence accumulates and critical comments are collected...
Reporting randomized, controlled trials of herbal interventions: an elaborated CONSORT statementJoel J Gagnier
University of Toronto, Institute for Evaluative Sciences, Toronto, Canada
Ann Intern Med 144:364-7. 2006..Item 4, concerning the herbal medicine intervention, required the most extensive elaboration. These recommendations have been developed to improve the reporting of RCTs using herbal medicine interventions...
Improving the quality of reporting of randomized controlled trials evaluating herbal interventions: implementing the CONSORT statement [corrected]Joel Gagnier
Department of Health Policy, Management and Evaluation, Department of Medicine, Univerity of Toronto, Toronto, Canada
Explore (NY) 2:143-9. 2006..Given that herbal medicinal products are widely used, vary greatly in content and quality, and are actively tested in randomized controlled trials (RCTs), such RCTs must clearly report the specifics of the intervention...
A critical appraisal of clinical practice guidelines for the treatment of lower-limb osteoarthritisJames N Pencharz
Institute of Medical Science, Faculty of Medicine, University of Toronto, ON, Canada
Arthritis Res 4:36-44. 2002..While most described the scope and intended patient populations, the guidelines varied considerably in the rigour of their development, coverage of implementation issues, and disclosure of conflicts of interest...
Outcome measures for clinical research in sepsis: a report of the 2nd Cambridge Colloquium of the International Sepsis ForumJohn C Marshall
Department of Surgery, Interdepartmental Division of Critical Care Medicine, University of Toronto, St Michael s Hospital, Canada
Crit Care Med 33:1708-16. 2005..We sought to evaluate existing approaches and to draw on insights from other disciplines to propose a comprehensive approach to outcome evaluation in sepsis clinical trials...
Algorithm for identification of undifferentiated peripheral inflammatory arthritis: a multinational collaboration through the 3e initiativeGlen Hazlewood
University of Toronto, Ontario, Canada
J Rheumatol Suppl 87:54-8. 2011..To develop an algorithm for identification of undifferentiated peripheral inflammatory arthritis (UPIA)...
Systematic monitoring of disease activity using an outcome measure improves outcomes in rheumatoid arthritisWanruchada Katchamart
Department of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada
J Rheumatol 37:1411-5. 2010..To systematically review the literature on the value of outcome measures to monitor treatment response in patients with rheumatoid arthritis (RA)...
Canadian recommendations for use of methotrexate in patients with rheumatoid arthritisWanruchada Katchamart
Department of Medicine, University of Toronto, Toronto, ON, Canada
J Rheumatol 37:1422-30. 2010..To develop recommendations for the use of methotrexate (MTX) in patients with rheumatoid arthritis...
Economic comparison of leflunomide and methotrexate in patients with rheumatoid arthritis: an evaluation based on a 1-year randomised controlled trialAndreas Maetzel
Arthritis and Immune Disorder Research Centre, University Health Network, Toronto, Ontario, Canada
Pharmacoeconomics 20:61-70. 2002..To compare disease-related medical care and productivity costs, and utilities, in 482 patients with rheumatoid arthritis randomised to receive leflunomide, methotrexate or placebo during a 12-month period...
Surfing for back pain patients: the nature and quality of back pain information on the InternetL Li
Healthcare Research Division, Arthritis and Autoimmunity Research Center, University Health Network, Toronto, Canada
Spine (Phila Pa 1976) 26:545-57. 2001..A prospective, systematic review of web sites related to back pain...
A guide to interpreting epidemiologic studies on the etiology of back painC Bombardier
Institute for Work and Health, Toronto, Ontario
Spine (Phila Pa 1976) 19:2047S-2056S. 1994....
Physical therapy management of low back pain: an exploratory survey of therapist approachesL C Li
Health Care Research Division, Arthritis and Autoimmunity Research Centre, University Health Network, 610 University Ave, 16th Floor, Toronto, Ontario, Canada M5G 2M9
Phys Ther 81:1018-28. 2001..The purpose of this study was to examine physical therapists' reported management of acute and subacute lumbar impairment...
A comparison of patients' responses about their disability with and without attribution to their affected areaR G Marx
Department of Surgery and Public Health Sciences, Clinical Epidemiology and Health Care Research Program, University of Toronto, The Hospital for Sick Children, 555 University Avenue, M5G 1X8, Toronto, ON, Canada
J Clin Epidemiol 54:580-6. 2001..Thus, both the wording of questions and order of questions can significantly affect patients' responses about their disability and raises questions about the validity of patients' reports of their disability...
A taxonomy for responsivenessD E Beaton
Institute for Work and Health, 250 Bloor St East, Ste 702, Toronto, Ontario, M4W 1E6, Canada
J Clin Epidemiol 54:1204-17. 2001..A questionnaire could thus be described as being "responsive to" a given category in the new taxonomy...
Implementing evidence-based guidelines for radiography in acute low back pain: a pilot study in a chiropractic communityCarlo Ammendolia
Canadian Memorial Chiropractic College, and Institute for Work and Health, 481 University Avenue, Suite 800, Toronto, Ontario M5G 2E9, Canada
J Manipulative Physiol Ther 27:170-9. 2004..To evaluate the ability of a systematic educational intervention strategy to change the plain radiography ordering behavior of chiropractors toward evidence-based practice for patients with acute low back pain (LBP)...
Efficacy and toxicity of methotrexate (MTX) monotherapy versus MTX combination therapy with non-biological disease-modifying antirheumatic drugs in rheumatoid arthritis: a systematic review and meta-analysisW Katchamart
Rheumatology Division, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Ann Rheum Dis 68:1105-12. 2009..To evaluate the efficacy and toxicity of methotrexate (MTX) monotherapy compared with MTX combination with non-biological disease-modifying antirheumatic drugs (DMARDs) in adults with rheumatoid arthritis...
Outcome assessments in the evaluation of treatment of spinal disorders: summary and general recommendationsC Bombardier
Institute for Work and Health, Toronto, Ontario, Canada
Spine (Phila Pa 1976) 25:3100-3. 2000..In addition to the five recommended domains, preference-based health outcome measures, including patients utilities, may be useful when there is a need to value alternative health outcomes...
Prognostic factors for time receiving workers' compensation benefits in a cohort of patients with low back painG McIntosh
Department of Public Health Sciences, University of Toronto, Canada
Spine (Phila Pa 1976) 25:147-57. 2000..Prospective inception cohort study...
A systematic review of the prognosis of acute whiplash and a new conceptual framework to synthesize the literatureP Cote
Institute for Work and Health, Toronto, Ontario, Canada
Spine (Phila Pa 1976) 26:E445-58. 2001..Systematic review of prognostic studies of acute whiplash...
Methodological quality and homogeneity influenced agreement between randomized trials and nonrandomized studies of the same intervention for back painAndrea D Furlan
Institute for Work and Health, Toronto, ON, Canada M5G 2E9
J Clin Epidemiol 61:209-31. 2008..Homogeneity was assessed regarding settings, population, interventions, and outcomes...
Simplified search strategies were effective in identifying clinical trials of pharmaceuticals and physical modalitiesDoreen Day
Institute for Work and Health, Toronto, ON, Canada
J Clin Epidemiol 58:874-81. 2005..Assess the efficacy of simplified search strategies and identify the best electronic bibliographic database for clinical trials in the field of musculoskeletal disorders and pain...
Views on radiography use for patients with acute low back pain among chiropractors in an Ontario communityCarlo Ammendolia
Canadian Memorial Chiropractic College, Toronto, Ontario, Canada
J Manipulative Physiol Ther 25:511-20. 2002..This practice is contrary to growing evidence that suggests only a small percentage of patients with acute low back pain require radiographic evaluation...
Multidisciplinary rehabilitation for chronic low back pain: systematic reviewJ Guzman
Institute for Work and Health, Toronto, Canada M4W 1E6
BMJ 322:1511-6. 2001..To assess the effect of multidisciplinary biopsychosocial rehabilitation on clinically relevant outcomes in patients with chronic low back pain...
"Are you better?" A qualitative study of the meaning of recoveryD E Beaton
Institute for Work and Health, Toronto, Ontario, Canada
Arthritis Rheum 45:270-9. 2001..quot; The purpose of this study was to explore the meaning of the concept of recovery (getting better) in a group of people with upper limb musculoskeletal disorders...
Identifying phases of investigation helps planning, appraising, and applying the results of explanatory prognosis studiesJ A Hayden
Centre for Research Expertise In Disability Outcomes, University Health Network Rehabilitation Solutions, Toronto, Canada
J Clin Epidemiol 61:552-60. 2008..To present an explanatory framework for understanding prognosis and illustrate it using data from a systematic review...
Group education interventions for people with low back pain. An overview of the literatureJ E Cohen
Ontario Workers Compensation Institute, Toronto, Canada
Spine (Phila Pa 1976) 19:1214-22. 1994..At 1 year of follow-up, there was no evidence in the six studies of clinically important benefits on any of the outcome measures. CONCLUSIONS. There is insufficient evidence to recommend group education for people with low back pain...
Identifying the best treatment among common nonsurgical neck pain treatments: a decision analysisGabrielle van der Velde
Institute for Work and Health, Toronto, ON, Canada
Spine (Phila Pa 1976) 33:S184-91. 2008..Decision analysis...
Quality of reporting of randomized controlled trials of herbal medicine interventionsJoel J Gagnier
Department of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, Ontario, Canada
Am J Med 119:800.e1-11. 2006..We suggest trialists consult a recent extension of the Consolidated Standard of Reporting Trials statement specific to herbal medicine trials when designing and reporting randomized controlled intervention trials of herbal medicines...
Low back painMaurits van Tulder
Institute for Work and Health, 481 University Avenue, Suite 800, Toronto, ON, M5G 2E9, Canada
Best Pract Res Clin Rheumatol 16:761-75. 2002..Consequently, it is still unclear what the most efficient strategy is for primary and secondary prevention. In general, multi-modal preventative approaches seem better able to reflect the clinical reality than single-modal interventions...
Utilization and costs of lumbar and full spine radiography by Ontario chiropractors from 1994 to 2001Carlo Ammendolia
University Health Network, Toronto, ON, Canada
Spine J 9:556-63. 2009..Evidence for the use of full spine radiography, except for the evaluation of scoliosis is lacking. It is uncertain what impact the growing evidence against their use has had on radiography utilization by Ontario chiropractors...
Examining heterogeneity in meta-analysis: comparing results of randomized trials and nonrandomized studies of interventions for low back painAndrea D Furlan
Institute for Work and Health, Toronto, Canada
Spine (Phila Pa 1976) 33:339-48. 2008..Literature review...
Minimal disease activity for rheumatoid arthritis: a preliminary definitionGeorge A Wells
Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
J Rheumatol 32:2016-24. 2005..This set of 2 definitions gained approval of 73% of the attendees. These (and other) definitions will now be subject to further validation in other databases...
The development of a comorbidity index with physical function as the outcomeDianne L Groll
Department of Surgery, Queen s University, Kingston, Ontario, Canada
J Clin Epidemiol 58:595-602. 2005..The objective of this study was to develop a self-administered Functional Comorbidity Index with physical function as the outcome...
Do chiropractors adhere to guidelines for back radiographs? A study of chiropractic teaching clinics in CanadaCarlo Ammendolia
Centre for Research Expertise in Improved Disability Outcomes, University Health Network, and Institute for Work and Health, University of Toronto, Toronto, Ontario, Canada
Spine (Phila Pa 1976) 32:2509-14. 2007..Clinical cohort...
Use of mainstream nonpharmacologic treatment by patients with arthritisLinda C Li
University Health Network and The Arthritis Society, Ontario Division, Toronto, Ontario, Canada
Arthritis Rheum 51:203-9. 2004..To examine the use of nonpharmacologic treatment by patients with osteoarthritis (OA) and rheumatoid arthritis (RA)...
The Work Instability Scale for Rheumatoid Arthritis (RA-WIS): Does it work in osteoarthritis?Kenneth Tang
Mobility Program Clinical Research Unit, St Michael s Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada
Qual Life Res 19:1057-68. 2010..To validate the 23-item Work Instability Scale for Rheumatoid Arthritis (RA-WIS) for use in osteoarthritis (OA) using both classical test theory and item response theory approaches...
Back belt use for prevention of occupational low back pain: a systematic reviewCarlo Ammendolia
Institute for Work and Health, Toronto, Ontario, Canada
J Manipulative Physiol Ther 28:128-34. 2005..Back pain continues to be the leading overall cause of morbidity and lost productivity in the workplace. Recently, there has been a renewed interest in the use of back belts by industry to reduce occupational low back pain (LBP)...
Worker productivity outcome measures in arthritisReuben Escorpizo
Department of Rehabilitation Science, University of Toronto, and Institute for Work and Health, Toronto, Ontario, Canada
J Rheumatol 34:1372-80. 2007..We recognize the need to perform psychometric testing of work outcome measures and to improve our ability to identify transitions (i.e., move in and out of a productivity state over time) made by workers with arthritis...
Adherence to radiography guidelines for low back pain: a survey of chiropractic schools worldwideCarlo Ammendolia
Clinical Epidemiologist, Rehabilitation Solutions, University Health Network, Toronto, Ontario, Canada
J Manipulative Physiol Ther 31:412-8. 2008..This study describes instruction provided at chiropractic schools worldwide on the use of spine radiography and compares instruction with evidence-based guidelines for low back pain...
A pattern recognition approach to the development of a classification system for upper-limb musculoskeletal disorders of workersDorcas E Beaton
Institute for Work and Health, 481 University Avenue, Toronto, Ontario, Canada
Scand J Work Environ Health 33:131-39. 2007..The purpose of this study was to use the clinical reasoning of experienced clinicians to recognize patterns of signs and symptoms and thus create a classification system...
Limited search strategies were effective in finding relevant nonrandomized studiesAndrea D Furlan
Institute for Work and Health, 481 University Av, Suite 800, Toronto, Ontario M5G 2E9, Canada
J Clin Epidemiol 59:1303-11. 2006..The purpose of this study was to develop and evaluate a method to limit search strategies according to study design of comparative nonrandomized studies (cNRSs)...
2009 updated method guidelines for systematic reviews in the Cochrane Back Review GroupAndrea D Furlan
Institute for Work and Health, 481 University Avenue, Toronto, Ontario, Canada
Spine (Phila Pa 1976) 34:1929-41. 2009..Method guidelines for systematic reviews of trials of treatments for neck and back pain...
Evaluation of the quality of prognosis studies in systematic reviewsJill A Hayden
Institute for Work and Health, University of Toronto, and Mount Sinai Hospital, Toronto, Ontario, Canada
Ann Intern Med 144:427-37. 2006..To provide valid assessments of answers to prognostic questions, systematic reviews must appraise the quality of the available evidence. However, no standard quality assessment method is currently available...
Reliability, validity, and responsiveness of five at-work productivity measures in patients with rheumatoid arthritis or osteoarthritisDorcas E Beaton
St Michael s Hospital, Institute for Work and Health, University of Toronto, Toronto, Ontario, Canada
Arthritis Care Res (Hoboken) 62:28-37. 2010..Our objective was to evaluate the relative strengths and weaknesses of 5 measures aimed at quantifying health-related at-work productivity loss and to determine the best available instrument for this population...
The Work Instability Scale for rheumatoid arthritis predicts arthritis-related work transitions within 12 monthsKenneth Tang
St Michael s Hospital, University of Toronto, Institute for Work and Health, Ontario, Canada
Arthritis Care Res (Hoboken) 62:1578-87. 2010..Our aim was to evaluate the ability of the Work Instability Scale for Rheumatoid Arthritis (RA-WIS) to predict arthritis-related work transitions within a 12-month period...
Initial patterns of clinical care and recovery from whiplash injuries: a population-based cohort studyPierre Cote
Institute for Work and Health, University of Toronto, Ontario, Canada
Arch Intern Med 165:2257-63. 2005..We designed a cohort study to determine whether patterns of early clinical care (involving visits to general practitioners, chiropractors, or specialists) were associated with different rates of recovery...
Measuring worker productivity: frameworks and measuresDorcas Beaton
Mobility Program Clinical Research Unit, St Michael s Hospital and the Institute for Work and Health, University of Toronto, Toronto, ON, Canada
J Rheumatol 36:2100-9. 2009..Progress has been made in this area, revealing an ambivalent set of results that directed us back to the need to further define and then contextualize the measurement of worker productivity...
Controversies in COX-2 selective inhibitionLee S Simon
Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
J Rheumatol 29:1501-10. 2002
An evidence-informed, integrated framework for rheumatoid arthritis careLinda C Li
University of British Columbia and Arthritis Research Centre of Canada, 895 West 10th Avenue, Vancouver, BC, Canada
Arthritis Rheum 59:1171-83. 2008
Stratifying the risk of NSAID-related upper gastrointestinal clinical events: results of a double-blind outcomes study in patients with rheumatoid arthritisLoren Laine
University of Southern California School of Medicine, Los Angeles, California 90033, USA
Gastroenterology 123:1006-12. 2002....
Cochrane back review groupLex M Bouter
Spine 28:1215-8. 2003
Quality of primary care guidelines for acute low back painMaurits W van Tulder
Institute for Research in Extramural Medicine EMGO, VU University Medical Center, Amsterdam, The Netherlands
Spine (Phila Pa 1976) 29:E357-62. 2004..Systematic review of clinical guidelines...
Effectiveness of the primary therapist model for rheumatoid arthritis rehabilitation: a randomized controlled trialLinda C Li
Ottawa Health Research Institute, Clinical Epidemiology Program, 1053 Carling Avenue, Administration Building Rm 2 014, Ottawa, Ontario K1Y 4E9, Canada
Arthritis Rheum 55:42-52. 2006....
An evidence-based approach to prescribing nonsteroidal antiinflammatory drugs. Third Canadian Consensus ConferenceHyman Tannenbaum
Rheumatic Disease Centre of Montreal, Montreal General Hospital, McGill University, Montreal, Quebec, Canada
J Rheumatol 33:140-57. 2006..To revisit our previous evidence-based recommendations on the appropriate prescription of nonsteroidal antiinflammatory drugs (NSAID) with particular emphasis on cyclooxygenase-2 selective inhibitors (coxibs)...
Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparisonChristopher P Cannon
Thrombolysis in Myocardial Infarction TIMI Study Group, Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Lancet 368:1771-81. 2006..The MEDAL programme was designed to provide a precise estimate of thrombotic cardiovascular events with the COX-2 selective inhibitor etoricoxib versus the traditional NSAID diclofenac...
Serious lower gastrointestinal clinical events with nonselective NSAID or coxib useLoren Laine
University of Southern California School of Medicine, Los Angeles 90033, USA
Gastroenterology 124:288-92. 2003..We performed a post hoc analysis of serious lower GI clinical events with a nonselective NSAID and a COX-2-selective agent in a prospective, double-blind, randomized GI outcomes trial...
Current topics on models of care in the management of inflammatory arthritisTheodora P M Vliet Vlieland
Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
J Rheumatol 33:1900-3. 2006....
Preliminary development of a responder index for chronic low back painLee S Simon
Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02465, USA
J Rheumatol 34:1386-91. 2007..The aim of the OMERACT Special Interest Group was to discuss the development and validation of a preliminary responder index in CLBP...
Practical considerations for the use of nonsteroidal anti-inflammatory drugs and cyclo-oxygenase-2 inhibitors in hypertension and kidney diseaseJacques Lelorier
Centre de recherche de l Hôtel Dieu du CHUM, Unité de recherche en pharmacoéconomie et pharmacoépidémiologie, Montreal, Canada
Can J Cardiol 18:1301-8. 2002..However, due to the presence of constitutive COX-2 in the human kidney, coxibs have the same potential for adverse renal effects as traditional NSAIDs...
Primary therapist model for patients referred for rheumatoid arthritis rehabilitation: a cost-effectiveness analysisLinda C Li
Ottawa Health Research Institute, and Arthritis Research Society of Canada, 895 West 10th Avenue, Vancouver, BC, Canada
Arthritis Rheum 55:402-10. 2006..To estimate the incremental cost-effectiveness (ICE) of services from a primary therapist compared with traditional physical therapists and/or occupational therapists for managing rheumatoid arthritis (RA), from the societal perspective...
Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope allelesPatricia Irigoyen
North Shore Long Island Jewish Institute for Medical Research, Manhasset, New York 11030, USA
Arthritis Rheum 52:3813-8. 2005..To examine the association between HLA-DRB1 alleles and the production of anti-cyclic citrullinated peptide (anti-CCP) and rheumatoid factor (RF) autoantibodies in patients with rheumatoid arthritis (RA)...
Training the next generation of researchers in work disability prevention: the Canadian Work Disability Prevention CIHR Strategic Training ProgramPatrick Loisel
Universite de Sherbrooke, Sherbrooke, Quebec, Canada
J Occup Rehabil 15:273-84. 2005..Training programs attracting high-quality applicants and taking into account the complexity of this emerging field are urgently needed...
Response to expression of concern regarding VIGOR studyClaire Bombardier
N Engl J Med 354:1196-9. 2006
Focusing on care research: a challenge and an opportunityLinda C Li
Arthritis Rheum 51:874-6. 2004
Updated method guidelines for systematic reviews in the cochrane collaboration back review groupMaurits van Tulder
Institute for Research in Extramural Medicine, Department of Clinical Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands
Spine (Phila Pa 1976) 28:1290-9. 2003..Descriptive method guidelines...
Setting priorities in arthritis care: Care III ConferenceLinda C Li
School of Rehabilitation Sciences, University of British Columbia, Vancouver, Canada
J Rheumatol 33:1891-4. 2006....
European Consensus Lupus Activity Measurement is sensitive to change in disease activity in childhood-onset systemic lupus erythematosusHermine I Brunner
Cincinnati Children s Hospital Medical Center and University of Cincinnati, Cincinnati, Ohio, USA
Arthritis Rheum 49:335-41. 2003..To confirm the construct validity and to characterize the measurement properties of the ECLAM by assessing its ability to predict damage and steroid requirements...
American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritisKenneth G Saag
University of Alabama, Birmingham, AL, USA
Arthritis Rheum 59:762-84. 2008
Advantages and limitations of utility assessment methods in rheumatoid arthritisAriel Beresniak
LIRAES, University Paris Descartes, Paris, France
J Rheumatol 34:2193-200. 2007..In light of these findings, real cost-effectiveness analyses based on observed clinical outcomes appear to be more robust and reliable to assist decision-making, particularly in the context of RA...
Interaction between smoking, the shared epitope, and anti-cyclic citrullinated peptide: a mixed picture in three large North American rheumatoid arthritis cohortsHye Soon Lee
Feinstein Institute for Medical Research, North Shore Long Island Jewish Health System, Manhasset, New York 11030, USA
Arthritis Rheum 56:1745-53. 2007..In an effort to confirm this interaction between smoking and shared epitope alleles, we performed a case-only analysis of 3 North American RA cohorts...
