Research Topics
| A K BoggildSummaryAffiliation: University of Toronto Country: Canada Publications
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Detail Information
Publications
Evaluation of a microculture method for isolation of Leishmania parasites from cutaneous lesions of patients in PeruAndrea K Boggild
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada
J Clin Microbiol 45:3680-4. 2007..2 days in NNN, and 6 days in 10% RPMI (P, 0.009). We have demonstrated that microculture is a more sensitive and time-efficient means of isolating Leishmania parasites from cutaneous lesions than traditional culture...
Diagnostic performance of filter paper lesion impression PCR for secondarily infected ulcers and nonulcerative lesions caused by cutaneous leishmaniasisAndrea K Boggild
Tropical Disease Unit, Toronto General Hospital, 200 Elizabeth Street, 13th Floor, North Wing, Room 1350, Toronto, ON M5G 1C4, Canada
J Clin Microbiol 49:1097-100. 2011..7% versus 100%) (P = 0.10). FPLI PCR is sensitive, specific, and unlike invasive procedures, can be used in secondarily infected ulcers. Invasive specimen collection is superior in nonulcerative lesions...
Latitudinal patterns of travel among returned travelers with influenza: results from the GeoSentinel Surveillance Network, 1997-2007Andrea K Boggild
Tropical Disease Unit, UHN Toronto General Hospital, Toronto, ON, M5G 2C4 Canada
J Travel Med 19:4-8. 2012..Influenza is a common vaccine-preventable disease among international travelers, but few data exist to guide use of reciprocal hemisphere or out-of-season vaccines...
Environmental hazards in Nepal: altitude illness, environmental exposures, injuries, and bites in travelers and expatriatesAndrea K Boggild
Department of Laboratory Medicine and Pathobiology, University of Toronto, ON, Canada
J Travel Med 14:361-8. 2007..Adventure travel necessarily places travelers at risk of environmental hazards. We assessed the burden of "environmental" hazards among a cohort of travelers and expatriates presenting to a large travel clinic in Nepal...
Optimization of microculture and evaluation of miniculture for the isolation of Leishmania parasites from cutaneous lesions in PeruAndrea K Boggild
Department of Laboratory Medicine and Pathobiology, University of Toronto, and Tropical Diseases Unit, Toronto General Hospital, Toronto, Ontario, Canada
Am J Trop Med Hyg 79:847-52. 2008..3%). Median time to positivity was three days by microculture and miniculture and five days by traditional culture (P<0.001). Microculture and miniculture are sensitive and efficient means of diagnosing CL...
Laboratory diagnosis of amoebic keratitis: comparison of four diagnostic methods for different types of clinical specimensAndrea K Boggild
Tropical Diseases Unit, Toronto General Hospital, Toronto, Ontario, Canada
J Clin Microbiol 47:1314-8. 2009..These findings have important implications for clinicians collecting diagnostic specimens and for diagnostic laboratories, especially in outbreak situations...
Detection and species identification of Leishmania DNA from filter paper lesion impressions for patients with American cutaneous leishmaniasisAndrea K Boggild
Tropical Disease Unit, Division of Infectious Diseases, Toronto General Hospital, Toronto, Canada
Clin Infect Dis 50:e1-6. 2010..We compared traditional diagnostic methods with a molecular noninvasive filter paper-based method for the diagnosis of cutaneous leishmaniasis...
Laboratory diagnosis of 2009 H1N1 influenza A virusAndrea K Boggild
Department of Infection Control, Mount Sinai Hospital, Toronto, Ontario
Crit Care Med 38:e38-42. 2010..We describe the current state of understanding around diagnostic testing and laboratory detection of 2009 H1N1 influenza A virus...
Clinical and demographic stratification of test performance: a pooled analysis of five laboratory diagnostic methods for American cutaneous leishmaniasisAndrea K Boggild
Division of Infectious Diseases, University Health Network Toronto General Hospital, Toronto, Ontario, Canada
Am J Trop Med Hyg 83:345-50. 2010..That clinical factors influence performance of non-molecular assays offers clinicians a patient-focused approach to diagnostic test selection...
Vaccine preventable diseases in returned international travelers: results from the GeoSentinel Surveillance NetworkAndrea K Boggild
Tropical Disease Unit, UHN Toronto General Hospital, 200 Elizabeth Street, North Wing, Toronto, ON, M5G 2C4, Canada
Vaccine 28:7389-95. 2010..typhi, and rabies. VPDs are significant contributors to morbidity and potential mortality in travelers. High rates of hospitalization make them an attractive target for pre-travel intervention...
The impact of influenza on the Canadian First NationsAndrea K Boggild
Tropical Disease Unit, Division of Infectious Diseases, UHN Toronto General Hospital, Toronto, ON
Can J Public Health 102:345-8. 2011..We herein provide a succinct review of our current understanding of the risk of influenza among First Nations populations in Canada...
Non-invasive cytology brush PCR diagnostic testing in mucosal leishmaniasis: superior performance to conventional biopsy with histopathologyAndrea K Boggild
Tropical Disease Unit, Division of Infectious Diseases, Toronto General Hospital, University of Toronto, Toronto, Canada
PLoS ONE 6:e26395. 2011..Traditional methods of diagnosing mucosal leishmaniasis (ML), such as biopsy with histopathology, are insensitive and require collection of an invasive diagnostic specimen...
Post-translational glutamylation and tyrosination in tubulin of tritrichomonads and the diplomonad Giardia intestinalisA K Boggild
Department of Biological Sciences, Auburn University, AL 36849, USA
Parasitol Res 88:58-62. 2002..This study is the first to report immunofluorescent localization of tubulin glutamylation in Giardia and confirms previously reported mass spectrometry data...
Atovaquone-proguanil: report from the CDC expert meeting on malaria chemoprophylaxis (II)Andrea K Boggild
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
Am J Trop Med Hyg 76:208-23. 2007..This topical review will examine the evidence behind the current indications for use of atovaquone-proguanil, and will summarize the current body of literature surrounding safety and tolerability...
Disseminated phaeohyphomycosis due to Ochroconis gallopavum in the setting of advanced HIV infectionAndrea K Boggild
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
Med Mycol 44:777-82. 2006..This case highlights both the diagnostic and management challenges posed by these infections. To our knowledge, this is the first reported case of disseminated phaeohyphomycosis due to Ochroconis gallopavum in a patient with HIV...
Prospective analysis of parasitic infections in Canadian travelers and immigrantsAndrea K Boggild
Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, ON, Canada
J Travel Med 13:138-44. 2006..The objective of this study was to prospectively assess the relative frequency of parasitic diseases in Canadian travelers and to characterize demographic and travel-related predictors of these infections...
Barriers to sun safety in a Canadian outpatient populationAndrea K Boggild
Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
J Cutan Med Surg 7:292-9. 2003..In this context, barriers can exist at the following three levels: knowledge of sun safety, acquisition of sun safety information, and implementation of specific sun protective measures...
Comparable growth of Tritrichomonas mobilensis in two commercially available culture mediaAndrea K Boggild
Faculty of Medicine, University of Toronto, Ontario, Canada
J Parasitol 88:1012-4. 2002..In assessing the practicality of the media, total cell amplification, as well as factors such as cost, ease of preparation, and storage capacity, were considered...
Localization of post-translationally modified alpha-tubulin and pseudocyst formation in tritrichomonadsAndrea K Boggild
Department of Biological Sciences, Auburn University, AL 36849, USA
Parasitol Res 88:468-74. 2002..Glutamylated tubulin appeared to be distributed throughout the axostyle and flagella, which fluoresced brightly in T. muris...
Use of peroxisome proliferator-activated receptor gamma agonists as adjunctive treatment for Plasmodium falciparum malaria: a randomized, double-blind, placebo-controlled trialAndrea K Boggild
Tropical Disease Unit, Toronto General Hospital of the University Health Network, Toronto, Ontario, Canada
Clin Infect Dis 49:841-9. 2009..We hypothesized that peroxisome proliferator-activated receptor gamma agonists (eg, rosiglitazone) would modulate the host's innate immune response to malaria and improve outcome...
Travel patterns and risk behaviour of HIV-positive people travelling internationallyIrving E Salit
Faculty of Medicine, University of Toronto, ON
CMAJ 172:884-8. 2005..These risks are even higher among immunocompromised people, such as those with HIV infection. We conducted a study to determine HIV-positive people's travel patterns and risk behaviours while abroad...
Leprosy in Toronto: an analysis of 184 imported casesAndrea K Boggild
Faculty of Medicine, University of Toronto, Toronto, Ont
CMAJ 170:55-9. 2004..Leprosy is uncommon in developed countries, but it is important for physicians to have a high index of suspicion when a foreign-born patient presents with chronic dermatitis and peripheral nerve involvement...
Travel patterns and risk behavior in solid organ transplant recipientsAndrea K Boggild
University of Toronto, Division of Infectious Diseases, Department of Medicine, UHN-Toronto General Hospital, Toronto, ON, Canada
J Travel Med 11:37-43. 2004..CONCLUSIONS: Solid organ transplant recipients represent a unique group of compromised travelers; however, few were adequately protected against travel-associated enteric, vector-borne and bloodborne pathogens...
Tropical pulmonary eosinophilia: a case series in a setting of nonendemicityAndrea K Boggild
Faculty of Medicine, McLaughlin Center for Molecular Medicine, University of Toronto, Toronto, Ontario, Canada
Clin Infect Dis 39:1123-8. 2004..In the untreated individual, TPE can lead to chronic and progressive respiratory compromise and death. Prompt recognition and treatment with diethylcarbamazine is therefore key to minimizing morbidity and mortality...
Leprosy: a primer for Canadian physiciansAndrea K Boggild
Faculty of Medicine, University of Toronto, Toronto, Ont
CMAJ 170:71-8. 2004..Because untreated leprosy can result in permanent, irreversible nerve damage and secondary transmission, early diagnosis and treatment are essential to minimize morbidity...
Delusional parasitosis: six-year experience with 23 consecutive cases at an academic medical centerAndrea K Boggild
Tropical Diseases Unit, Division of Infectious Diseases, University Health Network Toronto General Hospital, Ontario, Canada
Int J Infect Dis 14:e317-21. 2010..We conducted a case series with long-term questionnaire follow-up of delusional parasitosis patients presenting to our academic medical center...
Efficacy of atovaquone-proguanil for treatment of acute multidrug-resistant Plasmodium falciparum malaria in ThailandSrivicha Krudsood
Bangkok Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
Am J Trop Med Hyg 76:655-8. 2007..These data indicate that atovaquone-proguanil remains highly efficacious for the treatment of multidrug-resistant P. falciparum malaria in Thailand...
