Stuart K Bisland

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint A new technique for physiodesis using photodynamic therapy
    Stuart K Bisland
    Princess Margaret Hospital, Department of Medical Physics, Uniersity Health Network, Toronto, Ontario, Canada
    Clin Orthop Relat Res 461:153-61. 2007
  2. ncbi request reprint Pre-clinical in vitro and in vivo studies to examine the potential use of photodynamic therapy in the treatment of osteomyelitis
    Stuart K Bisland
    Ontario Cancer Institute, University Health Network, University of Toronto, 610 University Ave, Toronto, Canada
    Photochem Photobiol Sci 5:31-8. 2006
  3. ncbi request reprint Metronomic photodynamic therapy as a new paradigm for photodynamic therapy: rationale and preclinical evaluation of technical feasibility for treating malignant brain tumors
    Stuart K Bisland
    Ontario Cancer Institute, University Health Network, 610 University Avenue, Toronto, Ontario, Canada M5G 2M9
    Photochem Photobiol 80:22-30. 2004
  4. ncbi request reprint Increased expression of mitochondrial benzodiazepine receptors following low-level light treatment facilitates enhanced protoporphyrin IX production in glioma-derived cells in vitro
    S K Bisland
    Division of Biophysics and Bioimaging, University of Toronto, Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada M5G 2M9
    Lasers Surg Med 39:678-84. 2007
  5. ncbi request reprint Fluorescence image-guided brain tumour resection with adjuvant metronomic photodynamic therapy: pre-clinical model and technology development
    Arjen Bogaards
    Division of Biophysics and Bioimaging, Ontario Cancer Institute, University Health Network and University of Toronto, Toronto, Ontario, M5G 2M9, Canada
    Photochem Photobiol Sci 4:438-42. 2005
  6. ncbi request reprint Bioluminescence imaging of the response of rat gliosarcoma to ALA-PpIX-mediated photodynamic therapy
    Eduardo H Moriyama
    Department of Medical Biophysics, Ontario Cancer Institute, University of Toronto, Toronto M5G 2M9, Ontario, Canada
    Photochem Photobiol 80:242-9. 2004
  7. ncbi request reprint Photodynamic therapy of vertebral metastases: evaluating tumor-to-neural tissue uptake of BPD-MA and ALA-PpIX in a murine model of metastatic human breast carcinoma
    Margarete K Akens
    Division of Orthopaedic Surgery, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Photochem Photobiol 83:1034-9. 2007
  8. doi request reprint Effects of photodynamic therapy on the structural integrity of vertebral bone
    Emily Won
    Orthopaedic Biomechanics Laboratory, Division of Orthopaedics, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Spine (Phila Pa 1976) 35:272-7. 2010
  9. pmc High-frequency ultrasound assessment of antimicrobial photodynamic therapy in vitro
    Ralph E Baddour
    Department of Medical Biophysics, University of Toronto, Toronto, Canada
    J Biol Phys 33:61-6. 2007
  10. ncbi request reprint A simple two-step approach for introducing a protected diaminedithiol chelator during solid-phase assembly of peptides
    Jean Gariepy
    Ontario Cancer Institute, Princess Margaret Hospital, 610 University Avenue, Toronto, Ontario, Canada M5G 2M9
    Bioconjug Chem 13:679-84. 2002

Collaborators

Detail Information

Publications16

  1. ncbi request reprint A new technique for physiodesis using photodynamic therapy
    Stuart K Bisland
    Princess Margaret Hospital, Department of Medical Physics, Uniersity Health Network, Toronto, Ontario, Canada
    Clin Orthop Relat Res 461:153-61. 2007
    ..At 4 weeks posttreatment, limbs were shortened by an average of 9.5% +/- 4.4% without complication, confirming the potential application of photodynamic therapy for physiodesis...
  2. ncbi request reprint Pre-clinical in vitro and in vivo studies to examine the potential use of photodynamic therapy in the treatment of osteomyelitis
    Stuart K Bisland
    Ontario Cancer Institute, University Health Network, University of Toronto, 610 University Ave, Toronto, Canada
    Photochem Photobiol Sci 5:31-8. 2006
    ..In vivo, ALA-mediated PDT inhibited biofilm implants in bone. These results confirm that MB or ALA-mediated PDT have potential to treat S. aureus cultures grown in vitro or in vivo using an animal model of osteomyelitis...
  3. ncbi request reprint Metronomic photodynamic therapy as a new paradigm for photodynamic therapy: rationale and preclinical evaluation of technical feasibility for treating malignant brain tumors
    Stuart K Bisland
    Ontario Cancer Institute, University Health Network, 610 University Avenue, Toronto, Ontario, Canada M5G 2M9
    Photochem Photobiol 80:22-30. 2004
    ..The combined delivery of both drug and light during an extended period, without compromising survival of the animals, is demonstrated. Preliminary evidence of selective apoptosis of tumor under these conditions is presented...
  4. ncbi request reprint Increased expression of mitochondrial benzodiazepine receptors following low-level light treatment facilitates enhanced protoporphyrin IX production in glioma-derived cells in vitro
    S K Bisland
    Division of Biophysics and Bioimaging, University of Toronto, Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada M5G 2M9
    Lasers Surg Med 39:678-84. 2007
    ..Cells of astrocytic derivation within the brain express PBRs, while neurons express the central-type of benzodiazepine receptor...
  5. ncbi request reprint Fluorescence image-guided brain tumour resection with adjuvant metronomic photodynamic therapy: pre-clinical model and technology development
    Arjen Bogaards
    Division of Biophysics and Bioimaging, Ontario Cancer Institute, University Health Network and University of Toronto, Toronto, Ontario, M5G 2M9, Canada
    Photochem Photobiol Sci 4:438-42. 2005
    ..These results demonstrate that the combined treatment is technically feasible and this model is a candidate to evaluate it. Further optimization of mPDT treatment parameters (drug/light dose rates) is required to improve survival...
  6. ncbi request reprint Bioluminescence imaging of the response of rat gliosarcoma to ALA-PpIX-mediated photodynamic therapy
    Eduardo H Moriyama
    Department of Medical Biophysics, Ontario Cancer Institute, University of Toronto, Toronto M5G 2M9, Ontario, Canada
    Photochem Photobiol 80:242-9. 2004
    ..These results suggest that BLI can be used to provide spatiotemporal information of intracranial brain tumor responses after PDT and may serve as a valuable response-endpoint measure...
  7. ncbi request reprint Photodynamic therapy of vertebral metastases: evaluating tumor-to-neural tissue uptake of BPD-MA and ALA-PpIX in a murine model of metastatic human breast carcinoma
    Margarete K Akens
    Division of Orthopaedic Surgery, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Photochem Photobiol 83:1034-9. 2007
    ..The highest ratio for BPD-MA concentration was found 15 min after injection, which can be recommended for therapy in this model...
  8. doi request reprint Effects of photodynamic therapy on the structural integrity of vertebral bone
    Emily Won
    Orthopaedic Biomechanics Laboratory, Division of Orthopaedics, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Spine (Phila Pa 1976) 35:272-7. 2010
    ..This study investigates the effects of photodynamic therapy (PDT) on the structural integrity of vertebral bone in healthy rats...
  9. pmc High-frequency ultrasound assessment of antimicrobial photodynamic therapy in vitro
    Ralph E Baddour
    Department of Medical Biophysics, University of Toronto, Toronto, Canada
    J Biol Phys 33:61-6. 2007
    ..This highlights the potential for HFUS in rapidly and non-invasively assessing the structural changes related to antimicrobial response...
  10. ncbi request reprint A simple two-step approach for introducing a protected diaminedithiol chelator during solid-phase assembly of peptides
    Jean Gariepy
    Ontario Cancer Institute, Princess Margaret Hospital, 610 University Avenue, Toronto, Ontario, Canada M5G 2M9
    Bioconjug Chem 13:679-84. 2002
    ..Purified 99mTc-labeled constructs were found to accumulate in Chinese hamster ovary (CHO) cells in vitro as a function of charge and hydrophobicity...
  11. ncbi request reprint Volume CT with a flat-panel detector on a mobile, isocentric C-arm: pre-clinical investigation in guidance of minimally invasive surgery
    J H Siewerdsen
    Ontario Cancer Institute, Princess Margaret Hospital, Toronto, Ontario M5G 2M9, Canada
    Med Phys 32:241-54. 2005
    ..Future investigation includes improvement in image quality, particularly regarding x-ray scatter, motion artifacts and field of view, and integration with optical tracking and navigation systems...
  12. ncbi request reprint Photodynamic therapy for the treatment of metastatic lesions in bone: studies in rat and porcine models
    S Burch
    Ontario Cancer Institute, University Health Network, 610 University Avenue, Toronto, Ontario, Canada M5G 2M9
    J Biomed Opt 10:034011. 2005
    ..6 cm with an average fluence rate of 4.3 mW/cm2. Non-necrotic tissue damage was evident up to 2 cm out from the treatment fiber. Results support the application of PDT to the treatment of primary or metastatic lesions within bone...
  13. ncbi request reprint Photodynamic actinometry using microspheres: concept, development and responsivity
    Stuart K Bisland
    Princess Margaret Hospital, Ontario Cancer Institute, Toronto, Canada
    Photochem Photobiol 79:371-8. 2004
    ....
  14. ncbi request reprint Designing peptide-based scaffolds as drug delivery vehicles
    Richard D Brokx
    Department of Medical Biophysics, University of Toronto, 610 University Avenue, Ont, M5G 2M9, Toronto, Canada
    J Control Release 78:115-23. 2002
    ..Branched peptides such as loligomers represent simple and versatile molecular vehicles with potential applications in a wide variety of drug design approaches...
  15. ncbi request reprint Photodynamic therapy for the treatment of vertebral metastases in a rat model of human breast carcinoma
    S Burch
    The Spine Program, Division of Orthopaedic Surgery, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Ontario, Canada M4N 3M5
    J Orthop Res 23:995-1003. 2005
    ..The observations of paralysis following treatment highlight the importance of closely defining the therapeutic window of treatment in safety and efficacy...
  16. ncbi request reprint Multimodality imaging for vertebral metastases in a rat osteolytic model
    Shane Burch
    Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA, USA
    Clin Orthop Relat Res 454:230-6. 2007
    ..Early identification of metastasis is important when considering the use of this model to evaluate therapeutic outcomes directed toward vertebral metastasis...