Research Topics
| M D BerrySummaryAffiliation: University of Saskatchewan Country: Canada Publications
| Collaborators
|
Detail Information
Publications
N8-acetyl spermidine protects rat cerebellar granule cells from low K+-induced apoptosisM D Berry
Neuropsychiatry Research Unit, University of Saskatchewan, Saskatoon, Canada
J Neurosci Res 55:341-51. 1999..The lack of effect on basal apoptosis provides evidence of at least two forms of p53-independent apoptosis that can be regulated independently...
Glyceraldehyde-3-phosphate dehydrogenase and apoptosisM D Berry
Alviva Biopharmaceuticals, Inc, Suite 112C, 116, Research Drive, Innovation Place, Saskatoon, Saskatchewan, Canada
J Neurosci Res 60:150-4. 2000..This review summarizes the evidence implicating GAPDH in the initiation of one or more apoptotic cascades. The possible functions of GAPDH in the nucleus which could result in the initiation of apoptosis are also discussed...
Loss of mitochondrial membrane potential is dependent on the apoptotic program activated: prevention by R-2HMPD Zhang
Neuropsychiatry Research Unit, Department of Psychiatry, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
J Neurosci Res 58:284-92. 1999..The antiapoptotic drug R-N-2-heptyl-N-methylpropargylamine hydrochloride (R-2HMP) reversed this loss of mitochondrial membrane potential in Ara-c-induced apoptosis; the effect was antagonized by the S-2HMP...
Prolongation of life in an experimental model of aging in Drosophila melanogasterR G Jordens
Neuropsychiatry Research Unit, University of Saskatchewan, Saskatoon, Canada
Neurochem Res 24:227-33. 1999..5-1 ng/fly/day, led to a significant increase in mean and maximal life-span of galactose-treated, but not control flies. This effect was seen in both wild-type and mutant flies...
Schizophrenia, a neurodegenerative disorder with neurodevelopmental antecedentsP C Ashe
ALviva Biopharmaceuticals Inc, Saskatoon, Saskatchewan, Canada
Prog Neuropsychopharmacol Biol Psychiatry 25:691-707. 2001..Recent evidence suggests that the progressive course of schizophrenia is associated with ongoing neurodegenerative processes. Changes in brain derived neurotrophic factor (BDNF) may explain the various changes observed in schizophrenia...
