M Bernstein

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Surgical innovation or surgical evolution: an ethical and practical guide to handling novel neurosurgical procedures
    Mark Bernstein
    Division of Neurosurgery, Toronto Western Hospital, Ontario, Canada
    J Neurosurg 100:2-7. 2004
  2. doi request reprint Moral angst for surgical residents: a qualitative study
    Eva Knifed
    Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada
    Am J Surg 199:571-6. 2010
  3. pmc Information gaps for patients requiring craniotomy for benign brain lesion: a qualitative study
    Linda Rozmovits
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, 4 West Wing, Toronto, ON M5T2S8, Canada
    J Neurooncol 96:241-7. 2010
  4. pmc On pandemics and the duty to care: whose duty? who cares?
    Carly Ruderman
    Primary Care Research Unit, Department of Family and Community Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Room E3 49, Toronto, ON M4N 3M5, Canada
    BMC Med Ethics 7:E5. 2006
  5. pmc Adoption of an innovation to repair aortic aneurysms at a Canadian hospital: a qualitative case study and evaluation
    Nathalie M Danjoux
    Department of Health, Policy, Management and Evaluation, University of Toronto, Toronto, Canada
    BMC Health Serv Res 7:182. 2007
  6. pmc SARS and hospital priority setting: a qualitative case study and evaluation
    Jennifer A H Bell
    University of Toronto Joint Centre for Bioethics, University of Toronto, Toronto, Canada
    BMC Health Serv Res 4:36. 2004
  7. pmc Assessing the bioethical integrity of a clinical trial in surgery
    Mark Bernstein
    Department of Surgery, University of Toronto, Toronto Western Hospital, Toronto, Ont
    Can J Surg 47:329-32. 2004
  8. pmc Challenging beliefs and ethical concepts: the collateral damage of SARS
    Mark Bernstein
    Department of Surgery, University of Toronto and Division of Neurosurgery, Toronto Western Hospital, Toronto, Ontario Canada
    Crit Care 7:269-71. 2003
  9. ncbi request reprint Needs assessment of neurosurgery trainees: a survey study of two large training programs in the developing and developed worlds
    Mark Bernstein
    Department of Surgery, University of Toronto, Toronto, Canada M5G 1L5
    Surg Neurol 66:117-24; discussion 124-6. 2006
  10. ncbi request reprint Should a medical/surgical specialist with formal training in bioethics provide health care ethics consultation in his/her own area of speciality?
    Mark Bernstein
    University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada M5T 2S8
    HEC Forum 15:274-86. 2003

Collaborators

Detail Information

Publications84

  1. ncbi request reprint Surgical innovation or surgical evolution: an ethical and practical guide to handling novel neurosurgical procedures
    Mark Bernstein
    Division of Neurosurgery, Toronto Western Hospital, Ontario, Canada
    J Neurosurg 100:2-7. 2004
    ..In this paper the authors examine the challenges of defining surgical innovation and briefly review the literature on this challenging subject...
  2. doi request reprint Moral angst for surgical residents: a qualitative study
    Eva Knifed
    Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada
    Am J Surg 199:571-6. 2010
    ..The ethical dilemmas that residents experience throughout their training have not been explored qualitatively from surgical residents' perspectives...
  3. pmc Information gaps for patients requiring craniotomy for benign brain lesion: a qualitative study
    Linda Rozmovits
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, 4 West Wing, Toronto, ON M5T2S8, Canada
    J Neurooncol 96:241-7. 2010
    ....
  4. pmc On pandemics and the duty to care: whose duty? who cares?
    Carly Ruderman
    Primary Care Research Unit, Department of Family and Community Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Room E3 49, Toronto, ON M4N 3M5, Canada
    BMC Med Ethics 7:E5. 2006
    ....
  5. pmc Adoption of an innovation to repair aortic aneurysms at a Canadian hospital: a qualitative case study and evaluation
    Nathalie M Danjoux
    Department of Health, Policy, Management and Evaluation, University of Toronto, Toronto, Canada
    BMC Health Serv Res 7:182. 2007
    ....
  6. pmc SARS and hospital priority setting: a qualitative case study and evaluation
    Jennifer A H Bell
    University of Toronto Joint Centre for Bioethics, University of Toronto, Toronto, Canada
    BMC Health Serv Res 4:36. 2004
    ..The purpose of this study is to describe and evaluate priority setting in a hospital in response to SARS using the ethical framework 'accountability for reasonableness'...
  7. pmc Assessing the bioethical integrity of a clinical trial in surgery
    Mark Bernstein
    Department of Surgery, University of Toronto, Toronto Western Hospital, Toronto, Ont
    Can J Surg 47:329-32. 2004
  8. pmc Challenging beliefs and ethical concepts: the collateral damage of SARS
    Mark Bernstein
    Department of Surgery, University of Toronto and Division of Neurosurgery, Toronto Western Hospital, Toronto, Ontario Canada
    Crit Care 7:269-71. 2003
  9. ncbi request reprint Needs assessment of neurosurgery trainees: a survey study of two large training programs in the developing and developed worlds
    Mark Bernstein
    Department of Surgery, University of Toronto, Toronto, Canada M5G 1L5
    Surg Neurol 66:117-24; discussion 124-6. 2006
    ..We undertook a study to examine this issue, focusing on two large training programs, one in the developed world and one in the developing world...
  10. ncbi request reprint Should a medical/surgical specialist with formal training in bioethics provide health care ethics consultation in his/her own area of speciality?
    Mark Bernstein
    University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada M5T 2S8
    HEC Forum 15:274-86. 2003
  11. pmc Surgical outreach clinics in Canada: one neurosurgeon's experience
    Mark Bernstein
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Ont
    Can J Surg 47:25-8. 2004
    ..New surgical outreach clinics should be carefully planned. The specialist surgeon must have adequate flexibility and time for this activity and the success of the clinic must be assessed regularly...
  12. ncbi request reprint The inappropriate distribution of magnetic resonance imaging resources in Ontario
    Mark Bernstein
    Division of Neurosurgery, Department of Surgery, University Health Network, University of Toronto, Toronto, Ont
    Can Assoc Radiol J 55:309-10. 2004
  13. pmc Ethical issues in molecular medicine of relevance to surgeons
    Mark Bernstein
    Division of Neurosurgery, Toronto Western Hospital, Toronto, Ont
    Can J Surg 47:414-21. 2004
    ....
  14. pmc Ethical dilemmas encountered while operating and teaching in a developing country
    Mark Bernstein
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Ont
    Can J Surg 47:170-2. 2004
  15. ncbi request reprint Payment of research subjects involved in clinical trials is unethical
    Mark Bernstein
    Division of Neurosurgery, Toronto Western Hospital, Joint Center for Bioethics, University of Toronto, Toronto, Ontario, Canada
    J Neurooncol 63:223-4. 2003
  16. ncbi request reprint Conflict of interest: it is ethical for an investigator to also be the primary care-giver in a clinical trial
    Mark Bernstein
    Division of Neurosurgery, Toronto Western Hospital, Joint Centerfor Bioethics, University of Toronto, Toronto, Ontario, Canada
    J Neurooncol 63:107-8. 2003
  17. ncbi request reprint Surgical teaching: how should neurosurgeons handle the conflict of duty to today's patients with the duty to tomorrow's?
    M Bernstein
    Toronto Western Hospital, Toronto, Ontario, Canada
    Br J Neurosurg 17:121-3. 2003
    ..The author contends that both duties can be fulfilled simultaneously, but the surgical tension inherent in this situation must not be ignored or taken for granted...
  18. doi request reprint Is there too much variability in technical neurosurgery decision-making? Virtual Tumour Board of a challenging case
    Mark Bernstein
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada
    Acta Neurochir (Wien) 151:411-2; discussion 412-3. 2009
    ..A right pterional image-guided craniotomy successfully allowed for drainage of the cyst and resection of the nodule. The pathology was adamantinomatous craniopharyngioma. The patient had an excellent surgical recovery and a good outcome...
  19. ncbi request reprint Framework for bioethical assessment of an article on therapy
    Mark Bernstein
    Division of Neurosurgery, Toronto Western Hospital, Ontario, Canada
    J Neurosurg 98:485-90. 2003
    ..Comprehensive frameworks do not exist for the assessment of bioethical issues pertaining to research on human volunteers...
  20. pmc Wrong-side surgery: systems for prevention
    Mark Bernstein
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, Joint Centre for Bioethics, University of Toronto, Ont
    Can J Surg 46:144-6. 2003
  21. doi request reprint Neurosurgery patients' feelings about the role of residents in their care: a qualitative case study
    Eva Knifed
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Ontario, Canada
    J Neurosurg 108:287-91. 2008
    ..The role of residents in surgery is not clearly explained to patients. The authors undertook a study to explore the level of knowledge and anxiety in patients regarding residents' involvement in their surgery...
  22. ncbi request reprint Outpatient craniotomy for brain tumor: a pilot feasibility study in 46 patients
    M Bernstein
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, ON, Canada
    Can J Neurol Sci 28:120-4. 2001
    ..Proper prospective studies including satisfaction surveys would help resolve these issues and will be the next step...
  23. pmc Access to intensive care unit beds for neurosurgery patients: a qualitative case study
    D K Martin
    Department of Health Policy, Management and Evaluation, University of Toronto, Canada
    J Neurol Neurosurg Psychiatry 74:1299-303. 2003
    ....
  24. doi request reprint The history of awake craniotomy for brain tumor and its spread into Asia
    Julius July
    Division of Neurosurgery, University Health Network, Toronto Western Hospital, Toronto, Ontario, Canada M5T 2S8
    Surg Neurol 71:621-4; discussion 624-5. 2009
    ..Its spread to Asia could have significant impact based on the large population of patients and the low resource utilization associated with awake craniotomy...
  25. ncbi request reprint Awake craniotomy for removal of intracranial tumor: considerations for early discharge
    H J Blanshard
    Department of Anaesthesia, The Toronto Western Hospital, University of Toronto, 399 Bathurst Street, Toronto, Ontario, Canada M5T 2S8
    Anesth Analg 92:89-94. 2001
    ..Patient selection must be stringent with respect to the patient's preoperative functional status, tumor depth, surrounding edema, patient support at home, and ease of access to hospital for readmission...
  26. doi request reprint Day surgery awake craniotomy for removing brain tumours: technical note describing a simple protocol
    G Carrabba
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, 399 Bathurst Street, Toronto, Ontario, Canada
    Minim Invasive Neurosurg 51:208-10. 2008
    ....
  27. doi request reprint Development of a geometrically accurate imaging protocol at 3 Tesla MRI for stereotactic radiosurgery treatment planning
    B Zhang
    Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
    Phys Med Biol 55:6601-15. 2010
    ..We have developed a systematic approach to achieve confidence on the geometric integrity of a given imaging system/technique for clinical integration in SRS application...
  28. doi request reprint The consequence of delayed neurosurgical care at Tikur Anbessa Hospital, Addis Ababa, Ethiopia
    David W Cadotte
    Division of Neurosurgery, University of Toronto
    World Neurosurg 73:270-5. 2010
    ..Delayed neurosurgical care comes with a high personal and social cost. By measuring the time from diagnosis to treatment and taking note of institutional practices, changes can be initiated to improve patient waiting times...
  29. ncbi request reprint Nurse practitioner-based sign-out system to facilitate patient communication on a neurosurgical service: a pilot study with recommendations
    Deborah L Rabinovitch
    Department of Internal Medicine, Division of Psychiatry, University of Toronto, Canada
    J Neurosci Nurs 41:329-35. 2009
    ..Effective communication is important for reducing medical errors, and perhaps these modifications will facilitate this important endeavor...
  30. ncbi request reprint Advances in technology for intracranial stereotactic radiosurgery
    Arjun Sahgal
    Department of Radiation Oncology, Sunnybrook Odette Cancer Centre, The Princess Margaret Hospital, and the Joey Toby Tanenbaum family Gamma Knife Center, University of Toronto, Toronto, Ontario, Canada
    Technol Cancer Res Treat 8:271-80. 2009
    ..The focus of this review is to highlight recent advances and major innovations in SRS technologies relevant to clinical practice and developments allowing for non-invasive frame SRS...
  31. ncbi request reprint The nursing role in patient education regarding outpatient neurosurgical procedures
    Claudia Zanchetta
    Toronto Western Hospital, University Health Network, Ontario
    Axone 25:18-21. 2004
    ..This would undoubtedly improve cost-effectiveness for the system while simultaneously improving the patients' quality of life...
  32. ncbi request reprint Patient satisfaction with awake craniotomy for tumor surgery: a comparison of remifentanil and fentanyl in conjunction with propofol
    Pirjo H Manninen
    Department of Anesthesia, Toronto Western Hospital, Toronto, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Anesth Analg 102:237-42. 2006
    ..The use of remifentanil infusion in conjunction with propofol is a good alternative to fentanyl and propofol for conscious sedation for the awake craniotomy and these techniques are both well accepted by the patient...
  33. doi request reprint Differences in the perceived impact of sleep deprivation among surgical and non-surgical residents
    Sarah I Woodrow
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    Med Educ 42:459-67. 2008
    ..However, individuals' ability to recognise the effects of sleep deprivation has not been studied in medical education. We examined the perceived impact of sleep deprivation among different groups of postgraduate medical trainees...
  34. doi request reprint Outpatient brain tumor surgery: innovation in surgical neurooncology
    Mel Boulton
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Ontario, Canada
    J Neurosurg 108:649-54. 2008
    ..This report outlines a novel 11-year experience with outpatient image-guided biopsy and outpatient craniotomy for supratentorial intraaxial brain tumors...
  35. doi request reprint Cure following gene therapy for recurrent glioblastoma multiforme?
    K Karabatsou
    Division of Neurosurgery, Toronto Western Hospital, Toronto, Canada
    Acta Neurochir (Wien) 150:611-2. 2008
    ..We report a patient with glioblastoma multiforme who is alive and disease-free 13 years following aggressive treatment with multiple surgeries, radiotherapy, chemotherapy, and gene therapy...
  36. ncbi request reprint A qualitative study of attitudes toward error in patients facing brain tumour surgery
    Mark Bernstein
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada
    Can J Neurol Sci 31:208-12. 2004
    ..Medical error is an extremely important component of patient safety and requires intense study. The present investigation undertook to examine patients' perceptions and attitudes regarding medical error...
  37. doi request reprint Patients' perceptions of awake and outpatient craniotomy for brain tumor: a qualitative study
    Kathleen Joy Khu
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Ontario, Canada
    J Neurosurg 112:1056-60. 2010
    ..In this study the authors aim was to explore patients' perceptions about awake and outpatient craniotomy...
  38. ncbi request reprint Safety of intracranial aneurysm surgery performed in a postgraduate training program: implications for training
    Sarah I Woodrow
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, and the University of Toronto, Ontario, Canada
    J Neurosurg 102:616-21. 2005
    ..In this study the authors evaluated the experience profiles of neurosurgical trainees at a large Canadian academic center and the safety of their practice on patient care...
  39. doi request reprint What surgeons tell their patients about the intraoperative role of residents: a qualitative study
    Eva Knifed
    Department of Surgery, Division of Neurosurgery, University Health Network, University of Toronto, 4W451 399 Bathurst Street, Toronto, Ontario M5T2S8, Canada
    Am J Surg 196:788-94. 2008
    ..The issue of residents operating and disclosure to patients about this have not been explored from staff surgeons' perspectives...
  40. pmc Ethics and SARS: lessons from Toronto
    Peter A Singer
    University of Toronto Joint Centre for Bioethics, 88 College St, Toronto, Canada M5G 1L4
    BMJ 327:1342-4. 2003
  41. ncbi request reprint SARS and ethics
    Mark Bernstein
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, Joint Centre for Bioethics, University of Toronto, Toronto, Ontario, Canada
    Hosp Q 7:38-40. 2003
    ..The author briefly reviews the analysis by the JCB group and further examines how bioethical principles and theories relate to the numerous ethical issues raised by SARS and the methods used in its containment...
  42. ncbi request reprint Coincidence vs cause: cure in three glioblastoma patients treated with brachytherapy
    Amir R Dehdashti
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
    Can J Neurol Sci 34:339-42. 2007
    ..Survival of more than 10 years is extremely rare, especially when identified in 3 out of 71 patients assigned to one arm of a randomized controlled trial...
  43. doi request reprint Complications of Gamma Knife surgery: an early report from 2 Canadian centers
    Shobhan Vachhrajani
    Division of Neurosurgery, University of Toronto, Ontario, Canada
    J Neurosurg 109:2-7. 2008
    ..The authors report treatment complications from the early experience of 2 Canadian GKS programs in Toronto and Sherbrooke...
  44. pmc Patients' perception of the informed consent process for neurooncology clinical trials
    Eva Knifed
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Ontario, Canada
    Neuro Oncol 10:348-54. 2008
    ....
  45. ncbi request reprint Doctors' duty to disclose error: a deontological or Kantian ethical analysis
    Mark Bernstein
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
    Can J Neurol Sci 31:169-74. 2004
    ..The purpose of this discourse is to apply moral philosophical analysis to a delicate but important issue which will be a matter all physicians and surgeons will have to confront, probably numerous times, in their professional careers...
  46. pmc Patient satisfaction with outpatient lumbar microsurgical discectomy: a qualitative study
    Maria Hersht
    Division of Neurosurgery, Toronto Western Hospital and the University of Toronto, Toronto, Ontario, Canada
    Can J Surg 50:445-9. 2007
    ..We have been performing OLM since 1997 (MB) and 2002 (EMM), but no study of patient satisfaction has been carried out to date. the objective of our study was to investigate patient satisfaction with the experience...
  47. ncbi request reprint A qualitative study of the duty to care in communicable disease outbreaks
    Cécile M Bensimon
    Joint Centre for Bioethics, University of Toronto, Toronto, Canada
    Soc Sci Med 65:2566-75. 2007
    ..It can also enhance the focus of our current expectations of HCPs' duty during epidemics. This can be achieved by informing regulatory bodies, collaborating with policy makers and engaging the public...
  48. ncbi request reprint Complications in 622 cases of frame-based stereotactic biopsy, a decreasing procedure
    Paul N Kongkham
    Division of Neurosurgery, University of Toronto, Toronto, ON, Canada
    Can J Neurol Sci 35:79-84. 2008
    ..We reviewed the surgical experience of one surgeon to determine the nature and frequency of complications associated with this procedure...
  49. ncbi request reprint Prospective study of awake craniotomy used routinely and nonselectively for supratentorial tumors
    Demitre Serletis
    Division of Neurosurgery, Toronto Western Hospital, Toronto, Ontario, Canada
    J Neurosurg 107:1-6. 2007
    ..The authors prospectively assessed the value of awake craniotomy used nonselectively in patients undergoing resection of supratentorial tumors...
  50. ncbi request reprint Patient safety in surgery: error detection and prevention
    Edward Etchells
    Patient Safety Service, Sunnybrook and Womens College Health Sciences Center, 2075 Bayview Avenue, Room C410, Toronto, Ontario M4N 3M5, Canada
    World J Surg 27:936-41; discussion 941-2. 2003
    ....
  51. ncbi request reprint Prospective error recording in surgery: an analysis of 1108 elective neurosurgical cases
    Scellig Stone
    Division of Neurosurgery, University of Toronto, Toronto, Canada
    Neurosurgery 60:1075-80; discussion 1080-2. 2007
    ..Surgical error is common and contributes to complications for patients, necessitating detailed prospective collection and analysis of error data that emphasizes prevention...
  52. ncbi request reprint Capillary hemangioma of the cavernous sinus. Report of two cases
    May N Tsao
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, Ontario, Canada
    J Neurosurg 98:169-74. 2003
    ....
  53. ncbi request reprint Venous air embolism during awake craniotomy in a supine patient
    Mrinalini Balki
    Department of Anesthesia, The Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Can J Anaesth 50:835-8. 2003
    ..To report a non-fatal case of intraoperative venous air embolism (VAE) during an awake craniotomy. VAE presented with unusual clinical features...
  54. doi request reprint Gamma Knife patients' experience: lessons learned from a qualitative study
    Wendy Clifford
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, 399 Bathurst Street, 4 West Wing, Toronto, ON M5T 2S8, Canada
    J Neurooncol 92:387-92. 2009
    ..It is used to treat a variety of well-demarcated intracranial lesions, including brain tumors. This study aims to explore patients' perspectives of the GKSRS process and the various stages involved...
  55. ncbi request reprint Survival following surgery and prognostic factors for recently diagnosed malignant glioma: data from the Glioma Outcomes Project
    Edward R Laws
    Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    J Neurosurg 99:467-73. 2003
    ..Attempts were made to reduce the impact of selection bias by repeating the data analysis after omitting patients with major negative prognostic factors...
  56. ncbi request reprint Health and economic benefits of well-designed evaluations: some lessons from evaluating neuroblastoma screening
    Lee Soderstrom
    Department of Economics, McGill University, 855 Sherbrooke W, Montreal, Quebec, H3A 2T7, Canada
    J Natl Cancer Inst 97:1118-24. 2005
    ..It screened most Quebec newborns between 1989 and 1994 for neuroblastoma. As previously reported, the screening did not reduce neuroblastoma mortality and caused adverse health effects...
  57. ncbi request reprint Subcortical stimulation mapping
    Mark Bernstein
    J Neurosurg 100:365-6; discussion 366. 2004
  58. ncbi request reprint Is consent required for publication of medical errors?
    Karen Weisbaum
    Department of Family Medicine, Queen s University
    Healthc Q 8:66-9. 2005
    ....
  59. ncbi request reprint Marginal cases and moral relevance
    Mark Bernstein
    J Soc Philos 33:523-39. 2002
  60. pmc Delays in the operating room: signs of an imperfect system
    Janice Wong
    The Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ont, Canada
    Can J Surg 53:189-95. 2010
    ..Delays in the operating room have a negative effect on its efficiency and the working environment. In this prospective study, we analyzed data on perioperative system delays...
  61. doi request reprint Criteria for the ethical conduct of psychiatric neurosurgery clinical trials
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Canada
    Neurosurg Focus 29:E9. 2010
    ..Ethical criteria, such as the ones proposed here, need to be established now and applied in earnest if the field is to move forward and if patients with no other therapeutic options are to receive much-needed treatment...
  62. doi request reprint Personal identity, enhancement and neurosurgery: a qualitative study in applied neuroethics
    Nir Lipsman
    University of Toronto, Toronto, Ontario, Canada
    Bioethics 23:375-83. 2009
    ..The results provide insight into how patients approach their identity prior to potentially identity-altering procedures and what future ethical challenges lay ahead for clinicians and researchers in the field of neurotherapeutics...
  63. ncbi request reprint Prospective feasibility study of outpatient stereotactic brain lesion biopsy
    Ratan D Bhardwaj
    Division of Neurosurgery, University of Toronto, Ontario, Canada
    Neurosurgery 51:358-61; discussion 361-4. 2002
    ..To assess the safety and feasibility of performing computed tomography-guided stereotactic brain lesion biopsy as an outpatient day-surgery procedure...
  64. ncbi request reprint Postoperative reversal of complete (monocular) blindness in skull base meningioma: case report
    Joseph Bampoe
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Canada
    Can J Neurol Sci 30:72-4. 2003
    ..Recognition of this entity in the differential diagnosis of painless, progressive, and asymmetric optic neuropathy is important since reversal of visual loss is possible given timely surgical excision of the tumour...
  65. ncbi request reprint Pain, nausea, vomiting and ocular complications delay discharge following ambulatory microdiscectomy
    Shaheen Shaikh
    Department of Anesthesia, Division of Neurosurgery, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada
    Can J Anaesth 50:514-8. 2003
    ..Nowadays, microsurgical discectomy is being performed as an outpatient procedure. A retrospective chart review was done to document factors that delayed discharge or led to unanticipated admission...
  66. ncbi request reprint Outpatient lumbar microdiscectomy: a prospective study in 122 patients
    Ashutosh Singhal
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Can J Neurol Sci 29:249-52. 2002
    ..The object of this study was to examine the feasibility of performing lumbar microdiscectomy on an outpatient protocol and to examine the potential savings associated with such a protocol...
  67. ncbi request reprint House of healing, house of disrespect: a Kantian perspective on disrespectful behaviour among hospital workers
    Mark Bernstein
    Department of Surgery, University of Toronto, Toronto Western Hospital, Joint Center for Bioethics
    Hosp Q 6:62-6. 2002
    ..Some simple recommendations for improving disrespectful behaviour amongst hospital workers are offered...
  68. ncbi request reprint Rapid expansion of a previously asymptomatic subependymoma. Case report
    Adrian W Laxton
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Ontario, Canada
    J Neurosurg 103:1084-7. 2005
    ..To the authors' knowledge, this is the first reported case of rapid, nonhemorrhagic expansion associated with necrosis in a previously asymptomatic subependymoma...
  69. ncbi request reprint Surgical planning error: what's in a name?
    Mark Bernstein
    Division of Neurosurgery, Toronto Western Hospital, Ontario M5T 2S8, Toronto, Canada
    Lancet 362:908. 2003
  70. ncbi request reprint The voices of neurosurgeons: doctors' non-medical writing
    Mark Bernstein
    Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada
    Can J Neurol Sci 34:121-3. 2007
    ..The purpose of this article is to encourage fellow neurosurgeons to pursue this enjoyable and valuable endeavour, to utter a call to arms so to speak...
  71. ncbi request reprint Abetting emigration of Canada's nurses and doctors
    Mark Bernstein
    Department of Surgery, University of Toronto Division of Neurosurgery, Toronto Western Hospital, University Health Network
    Healthc Q 8:8-9. 2005
  72. ncbi request reprint Dose escalation and pharmacokinetics of pegylated liposomal doxorubicin (Doxil) in children with solid tumors: a pediatric oncology group study
    Neyssa M Marina
    Department of Pediatrics, Stanford University Medical Center, Stanford, CA 94305 5208, USA
    Clin Cancer Res 8:413-8. 2002
    ..To determine the maximum tolerated dose and pharmacokinetics of Doxil in children with recurrent or refractory solid tumors. Doxil is pegylated doxorubicin...
  73. ncbi request reprint Phase I study of the proteasome inhibitor bortezomib in pediatric patients with refractory solid tumors: a Children's Oncology Group study (ADVL0015)
    Susan M Blaney
    Texas Children s Cancer Center, Baylor College of Medicine, Houston, TX, USA
    J Clin Oncol 22:4804-9. 2004
    ..To determine the maximum-tolerated dose, dose-limiting toxicity (DLT), and pharmacodynamics of the proteasome inhibitor bortezomib (formerly PS-341) in children with recurrent or refractory solid tumors...
  74. ncbi request reprint Pharmacokinetics of O(6)-benzylguanine in pediatric patients with central nervous system tumors: a pediatric oncology group study
    Kathleen Neville
    Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
    Clin Cancer Res 10:5072-5. 2004
    ....
  75. ncbi request reprint Influence of phenytoin on the disposition of irinotecan: a case report
    Daryl J Murry
    Texas Children s Cancer Center Baylor College of Medicine, Houston, USA
    J Pediatr Hematol Oncol 24:130-3. 2002
    ..Further detailed pharmacokinetic studies of irinotecan in patients receiving concomitant therapy with enzyme-inducing anticonvulsants are required so that rational dosing recommendations can be provided for this patient population...
  76. pmc Fully informed consent is impossible in surgical clinical trials
    Mark Bernstein
    Can J Surg 48:271-2. 2005
  77. ncbi request reprint Phase II study of nelarabine (compound 506U78) in children and young adults with refractory T-cell malignancies: a report from the Children's Oncology Group
    Stacey L Berg
    Texas Children s Cancer Center, Baylor College of Medicine, 6621 Fannin St, MC3 3320, Houston, TX 77030, USA
    J Clin Oncol 23:3376-82. 2005
    ..We sought to define the response rate of nelarabine in children and young adults with refractory or recurrent T-cell disease...
  78. ncbi request reprint Internet censorship in the hospital: bad ethics and great irony
    Mark Bernstein
    Healthc Q 7:8. 2004
  79. ncbi request reprint When the bone flap hits the floor
    Michael Gardam
    Neurosurgery 60:E208; author reply E208. 2007
  80. ncbi request reprint Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group
    H Stacy Nicholson
    Department of Pediatrics, Oregon Health Science and University, Portland, Oregon, USA
    Cancer 110:1542-50. 2007
    ..Effective chemotherapy is lacking for most types of central nervous system (CNS) tumors in children. Temozolomide, an agent with activity against adult brain tumors, was investigated in children and adolescents with recurrent CNS tumors...
  81. ncbi request reprint Fourth ventricle epidermoid tumor: radiologic, intraoperative, and pathologic findings
    Reza Forghani
    Department of Radiology, McGill University Health Center, Montreal General Hospital, Montreal, QC, Canada
    Radiographics 27:1489-94. 2007
  82. ncbi request reprint Perioperative complications and neurological outcomes of first and second craniotomies among patients enrolled in the Glioma Outcome Project
    Susan M Chang
    Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, California 94143 0372, USA
    J Neurosurg 98:1175-81. 2003
    ..Factors predicting neurological outcome would also be helpful for patient selection for surgically based clinical trials...
  83. ncbi request reprint Phase II trial of irinotecan in children with refractory solid tumors: a Children's Oncology Group Study
    Lisa R Bomgaars
    Baylor College of Medicine, Houston, TX, USA
    J Clin Oncol 25:4622-7. 2007
    ..A phase II study was performed to determine the efficacy of irinotecan (IRN) in children with refractory solid tumors. Secondary objectives were to evaluate toxicity, pharmacokinetics, pharmacodynamics, and UGT1A1 genotype...