Affiliation: University of Toronto
Berger A, Paige C. Hemokinin-1 has Substance P-like function in U-251 MG astrocytoma cells: a pharmacological and functional study. J Neuroimmunol. 2005;164:48-56 pubmed
..Moreover, we show TAC4 mRNA expression in gliomas, indicating a possible involvement of HK-1 in glioma biology. ..
Berger A, Tran A, Paige C. Co-regulated decrease of Neurokinin-1 receptor and Hemokinin-1 gene expression in monocytes and macrophages after activation with pro-inflammatory cytokines. J Neuroimmunol. 2007;187:83-93 pubmed
..A co-regulated decrease could also be observed in differentiating primary bone marrow macrophages, suggesting that this receptor-ligand pair may be controlled by cytokine networks and may serve a developmental role in the immune system. ..
Berger A, Benveniste P, Corfe S, Tran A, Barbara M, Wakeham A, et al
. Targeted deletion of the tachykinin 4 gene (TAC4-/-) influences the early stages of B lymphocyte development. Blood. 2010;116:3792-801 pubmed publisher
Berger A, Tran A, Dida J, Minkin S, Gerard N, Yeomans J, et al
. Diminished pheromone-induced sexual behavior in neurokinin-1 receptor deficient (TACR1(-/-)) mice. Genes Brain Behav. 2012;11:568-76 pubmed publisher
..NK-1R signaling may therefore play an important role in pheromone-induced sexual behavior. ..