C Beaulieu

Summary

Affiliation: University of Alberta
Country: Canada

Publications

  1. ncbi request reprint Imaging brain connectivity in children with diverse reading ability
    Christian Beaulieu
    Department of Biomedical Engineering, Faculty of Medicine and Dentistry, University of Alberta, 1098 Research Transition Facility, Edmonton, Alberta, Canada T6G 2V2
    Neuroimage 25:1266-71. 2005
  2. ncbi request reprint The basis of anisotropic water diffusion in the nervous system - a technical review
    Christian Beaulieu
    Department of Biomedical Engineering, Faculty of Medicine, University of Alberta, Edmonton, Canada
    NMR Biomed 15:435-55. 2002
  3. ncbi request reprint Spreading waves of transient and prolonged decreases in water diffusion after subarachnoid hemorrhage in rats
    C Beaulieu
    Department of Radiology, Lucas MRI Center, Stanford University, Stanford, California, USA
    Magn Reson Med 44:110-6. 2000
  4. ncbi request reprint Dynamics of cerebral injury, perfusion, and blood-brain barrier changes after temporary and permanent middle cerebral artery occlusion in the rat
    A Kastrup
    Department of Radiology, Lucas MRS Center, Stanford University School of Medicine, CA 94305 5488, USA
    J Neurol Sci 166:91-9. 1999
  5. doi request reprint Thalamic diffusion and volumetry in temporal lobe epilepsy with and without mesial temporal sclerosis
    Gaolang Gong
    Department of Biomedical Engineering, University of Alberta, Alberta, Canada
    Epilepsy Res 80:184-93. 2008
  6. ncbi request reprint Bilateral white matter diffusion changes persist after epilepsy surgery
    Luis Concha
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Epilepsia 48:931-40. 2007
  7. doi request reprint In vivo diffusion tensor imaging and histopathology of the fimbria-fornix in temporal lobe epilepsy
    Luis Concha
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada T6G 2B7
    J Neurosci 30:996-1002. 2010
  8. doi request reprint Brain microstructure is related to math ability in children with fetal alcohol spectrum disorder
    Catherine Lebel
    Department of Biomedical Engineering, University of Alberta, Alberta, Canada
    Alcohol Clin Exp Res 34:354-63. 2010
  9. ncbi request reprint Relaxation times and microstructures
    F R Fenrich
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    NMR Biomed 14:133-9. 2001
  10. doi request reprint Insights into the sequence of structural consequences of convulsive status epilepticus: a longitudinal MRI study
    Gaolang Gong
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Epilepsia 49:1941-5. 2008

Collaborators

Detail Information

Publications45

  1. ncbi request reprint Imaging brain connectivity in children with diverse reading ability
    Christian Beaulieu
    Department of Biomedical Engineering, Faculty of Medicine and Dentistry, University of Alberta, 1098 Research Transition Facility, Edmonton, Alberta, Canada T6G 2V2
    Neuroimage 25:1266-71. 2005
    ..The maturation of the white matter may play a key role in the development of cognitive processes such as reading...
  2. ncbi request reprint The basis of anisotropic water diffusion in the nervous system - a technical review
    Christian Beaulieu
    Department of Biomedical Engineering, Faculty of Medicine, University of Alberta, Edmonton, Canada
    NMR Biomed 15:435-55. 2002
    ..Pertinent pathological models, developmental studies and theoretical analyses provide further insight into the basis of anisotropic diffusion and its potential utility in the nervous system...
  3. ncbi request reprint Spreading waves of transient and prolonged decreases in water diffusion after subarachnoid hemorrhage in rats
    C Beaulieu
    Department of Radiology, Lucas MRI Center, Stanford University, Stanford, California, USA
    Magn Reson Med 44:110-6. 2000
    ..Therefore, spreading depression-like cellular depolarization is a consequence of acute subarachnoid hemorrhage in rats. Magn Reson Med 44:110-116, 2000...
  4. ncbi request reprint Dynamics of cerebral injury, perfusion, and blood-brain barrier changes after temporary and permanent middle cerebral artery occlusion in the rat
    A Kastrup
    Department of Radiology, Lucas MRS Center, Stanford University School of Medicine, CA 94305 5488, USA
    J Neurol Sci 166:91-9. 1999
    ..Our results demonstrate that with advanced MRI techniques, alterations of the BBB can be correlated with the hemodynamic and biophysical consequences of reperfusion...
  5. doi request reprint Thalamic diffusion and volumetry in temporal lobe epilepsy with and without mesial temporal sclerosis
    Gaolang Gong
    Department of Biomedical Engineering, University of Alberta, Alberta, Canada
    Epilepsy Res 80:184-93. 2008
    ..The purpose of this study was to investigate the status of thalamic integrity by using DTI as well as volumetric MRI in adult TLE+ and TLE- patients...
  6. ncbi request reprint Bilateral white matter diffusion changes persist after epilepsy surgery
    Luis Concha
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Epilepsia 48:931-40. 2007
    ..We performed a longitudinal study in patients with unilateral MTS who were seizure-free for 1 year after surgery to determine whether the observed presurgical white matter diffusion abnormalities were reversible...
  7. doi request reprint In vivo diffusion tensor imaging and histopathology of the fimbria-fornix in temporal lobe epilepsy
    Luis Concha
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada T6G 2B7
    J Neurosci 30:996-1002. 2010
    ....
  8. doi request reprint Brain microstructure is related to math ability in children with fetal alcohol spectrum disorder
    Catherine Lebel
    Department of Biomedical Engineering, University of Alberta, Alberta, Canada
    Alcohol Clin Exp Res 34:354-63. 2010
    ..The goal of this study was to use diffusion tensor imaging (DTI) to investigate the relationship between mathematical skill and brain white matter structure in children with FASD...
  9. ncbi request reprint Relaxation times and microstructures
    F R Fenrich
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    NMR Biomed 14:133-9. 2001
    ....
  10. doi request reprint Insights into the sequence of structural consequences of convulsive status epilepticus: a longitudinal MRI study
    Gaolang Gong
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Epilepsia 49:1941-5. 2008
    ..Our findings provide evidence that status epilepticus can induce permanent hippocampal damage with the delayed timing of the structural changes being consistent with programmed cell death...
  11. doi request reprint Diffusion tensor imaging tractography and reliability analysis for limbic and paralimbic white matter tracts
    Nikolai Malykhin
    Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada
    Psychiatry Res 164:132-42. 2008
    ..97 (0.99), ventromedial prefrontal white matter 0.92 (0.93), crus of fornix 0.80 (0.81). The reported DTI protocol provides a reliable method to analyze limbic and paralimbic white matter tracts relevant to psychiatric disorders...
  12. doi request reprint Lateralization of the arcuate fasciculus from childhood to adulthood and its relation to cognitive abilities in children
    Catherine Lebel
    Department of Biomedical Engineering, University of Alberta, Alberta, Canada
    Hum Brain Mapp 30:3563-73. 2009
    ....
  13. doi request reprint Low cerebral blood volume is predictive of diffusion restriction only in hyperacute stroke
    Michael Knash
    Division of Neurology, University of Alberta, Edmonton, Alberta, Canada
    Stroke 41:2795-800. 2010
    ..We tested the hypothesis that CBV would decrease proportionally to the apparent diffusion coefficient in patients with acute stroke and thus could be used as a surrogate parameter for diffusion restriction...
  14. ncbi request reprint Extratemporal white matter abnormalities in mesial temporal lobe epilepsy demonstrated with diffusion tensor imaging
    Donald W Gross
    Division of Neurology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Epilepsia 47:1360-3. 2006
    ....
  15. doi request reprint Diffusion tensor imaging of white matter tract evolution over the lifespan
    C LeBel
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Neuroimage 60:340-52. 2012
    ..This study demonstrates clear age-related microstructural changes throughout the brain white matter, and provides normative data that will be useful for studying white matter development in a variety of diseases and abnormal conditions...
  16. doi request reprint White-matter diffusion abnormalities in temporal-lobe epilepsy with and without mesial temporal sclerosis
    L Concha
    Department of Biomedical Engineering, University of Alberta, Alberta, Canada
    J Neurol Neurosurg Psychiatry 80:312-9. 2009
    ..The purpose of this study was to determine if said white-matter abnormalities are related to the presence of MTS or if they are also present in non-lesional TLE...
  17. doi request reprint Microstructural maturation of the human brain from childhood to adulthood
    C LeBel
    Department of Biomedical Engineering, Faculty of Medicine and Dentistry, Room 1098 Research Transition Facility, University of Alberta, Edmonton, Alberta, Canada T6G 2V2
    Neuroimage 40:1044-55. 2008
    ..These in vivo results expand upon previous postmortem and imaging studies and provide quantitative measures indicative of the progression and magnitude of regional human brain maturation...
  18. doi request reprint Sodium imaging intensity increases with time after human ischemic stroke
    Muhammad S Hussain
    Division of Neurology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Ann Neurol 66:55-62. 2009
    ..Utilizing high-quality sodium images, we tested the hypothesis that sodium signal intensity increases with time from symptom onset in human ischemic stroke...
  19. pmc Mapping anatomical connectivity patterns of human cerebral cortex using in vivo diffusion tensor imaging tractography
    Gaolang Gong
    Department of Biomedical Engineering, 1098 Research Transition Facility, University of Alberta, Edmonton, Alberta, Canada
    Cereb Cortex 19:524-36. 2009
    ..Our results are compatible with previous structural and functional brain networks studies and provide insight into the organizational principles of human brain anatomical networks that underlie functional states...
  20. doi request reprint Elevations of diffusion anisotropy are associated with hyper-acute stroke: a serial imaging study
    Yusuf A Bhagat
    Department of Biomedical Engineering, University of Alberta, 1098 Research Transition Facility, Edmonton, Alberta, Canada T6G 2V2
    Magn Reson Imaging 26:683-93. 2008
    ..11, n=4), subcortical WM (1.13+/-0.14, n=4), deep GM (1.07+/-0.06, n=1) and cortical GM (1.22+/-0.13, n=5) hyperacutely (< or =7 h); however, reductions of rFA at approximately 24 h post stroke were more consistent (rFA= 0.85+/-0.12)...
  21. ncbi request reprint Bilateral limbic diffusion abnormalities in unilateral temporal lobe epilepsy
    Luis Concha
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Ann Neurol 57:188-96. 2005
    ..Our findings suggest that TLE with unilateral mesial temporal sclerosis is associated with bilateral limbic system pathology...
  22. ncbi request reprint Diffusion tensor tractography of the limbic system
    Luis Concha
    Department of Biomedical Engineering University of Alberta, Edmonton, Alberta, Canada
    AJNR Am J Neuroradiol 26:2267-74. 2005
    ..We investigated the effect of CSF signal intensity suppression on fiber tracking of the limbic connections and characterized the diffusion properties of these structures in healthy volunteers...
  23. ncbi request reprint The relationship between diffusion anisotropy and time of onset after stroke
    Yusuf A Bhagat
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    J Cereb Blood Flow Metab 26:1442-50. 2006
    ..Similar anisotropy changes were noted in subcortical WM regions in the gyri...
  24. doi request reprint The effect of concomitant gradient fields on diffusion tensor imaging
    C A Baron
    Department of Biomedical Engineering, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
    Magn Reson Med 68:1190-201. 2012
    ..A prospective correction scheme that can reduce concomitant gradient errors is proposed and verified for diffusion imaging...
  25. ncbi request reprint Comparison of diffusion, blood oxygenation, and blood volume changes during global ischemia in rats
    A J de Crespigny
    Lucas Center, Department of Radiology, Stanford University, Stanford, California, USA
    Magn Reson Med 45:10-6. 2001
    ..The initial 5% ADC drop may be a vascular artifact. The rapidity of the CBV-weighted signal drop suggests a flow-mediated contribution to the iron oxide contrast mechanism. Magn Reson Med 45:10-16, 2001...
  26. doi request reprint Age-related regional variations of the corpus callosum identified by diffusion tensor tractography
    Catherine Lebel
    Department of Biomedical Engineering, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
    Neuroimage 52:20-31. 2010
    ....
  27. ncbi request reprint Diffusion tensor spectroscopy (DTS) of human brain
    Jacob Ellegood
    Department of Biomedical Engineering, University of Alberta, Edmonton, Canada
    Magn Reson Med 55:1-8. 2006
    ..The principal diffusion direction derived for NAA was in good agreement with expected anatomic tract directions in the white matter...
  28. ncbi request reprint Corpus callosum and cingulum tractography in Parkinson's disease
    Katie Wiltshire
    Glenrose Rehabilitation Hospital, Edmonton, Alberta, Canada
    Can J Neurol Sci 37:595-600. 2010
    ..Diffusion tensor imaging is a quantitative imaging method sensitive to the micro-structure of white matter tracts...
  29. ncbi request reprint Spatial profiling of the corticospinal tract in amyotrophic lateral sclerosis using diffusion tensor imaging
    John C T Wong
    Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
    J Neuroimaging 17:234-40. 2007
    ..Diffusion tensor imaging (DTI) was used as a noninvasive method to evaluate the anatomy of the corticospinal tract (CST) and the pattern of its degeneration in amyotrophic lateral sclerosis (ALS)...
  30. ncbi request reprint Diffusion tensor imaging of time-dependent axonal and myelin degradation after corpus callosotomy in epilepsy patients
    Luis Concha
    Department of Biomedical Engineering, Faculty of Medicine and Dentistry, 1098 Research Transition Facility, University of Alberta, Edmonton, Alberta, Canada T6G 2V2
    Neuroimage 32:1090-9. 2006
    ..DTI is capable of non-invasively detecting, staging and following the microstructural degradation of white matter following axonal injury...
  31. ncbi request reprint Diffusion tensor imaging of neurodevelopment in children and young adults
    Lindsay Snook
    Department of Biomedical Engineering, Faculty of Medicine and Dentistry, 1098 Research Transition Facility, University of Alberta, Edmonton, AB, Canada T6G 2V2
    Neuroimage 26:1164-73. 2005
    ..These findings suggest a continuation of the brain's microstructural development through adolescence...
  32. ncbi request reprint Comparison of generalized autocalibrating partially parallel acquisitions and modified sensitivity encoding for diffusion tensor imaging
    Y A Bhagat
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    AJNR Am J Neuroradiol 28:293-8. 2007
    ....
  33. ncbi request reprint Trace apparent diffusion coefficients of metabolites in human brain using diffusion weighted magnetic resonance spectroscopy
    Jacob Ellegood
    Department of Biomedical Engineering, University of Alberta, Edmonton, Canada
    Magn Reson Med 53:1025-32. 2005
    ..The mean diffusivity of NAA (0.14 +/- 0.03 x 10(-3) mm(2)/s) appears to be less than that of tCr (0.17 +/- 0.04 x 10(-3) mm(2)/s) and Cho (0.18 +/- 0.05 x 10(-3) mm(2)/s) in human brain...
  34. ncbi request reprint Diffusion anisotropy in subcortical white matter and cortical gray matter: changes with aging and the role of CSF-suppression
    Yusuf A Bhagat
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta T6G 2V2, Canada
    J Magn Reson Imaging 20:216-27. 2004
    ....
  35. ncbi request reprint Anisotropic diffusion of metabolites in peripheral nerve using diffusion weighted magnetic resonance spectroscopy at ultra-high field
    Jacob Ellegood
    Department of Biomedical Engineering, University of Alberta, 1098 Research Transition Facility, Edmonton, Alta, Canada T6G 2V2
    J Magn Reson 184:20-8. 2007
    ....
  36. ncbi request reprint Comparison of multislice and single-slice acquisitions for pulsed arterial spin labeling measurements of cerebral perfusion
    Alison M Campbell
    Department of Biomedical Engineering, Faculty of Medicine and Dentistry, 1098 Research Transition Facility, University of Alberta, Edmonton, Alberta, Canada T6G 2V2
    Magn Reson Imaging 24:869-76. 2006
    ..If limited brain coverage is acceptable, perfusion images with greater SNR are achievable with limited slices and placement of the tagging region immediately adjacent to the site of interest...
  37. ncbi request reprint Pulsed arterial spin labeling parameter optimization for an elderly population
    Alison M Campbell
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada T6G 2V2
    J Magn Reson Imaging 23:398-403. 2006
    ..To optimize pulsed arterial spin labeling (PASL) parameters for the elderly to take into account possible perfusion changes that occur in the brain with age...
  38. ncbi request reprint In vivo sodium magnetic resonance imaging of the human brain using soft inversion recovery fluid attenuation
    Robert Stobbe
    Department of Biomedical Engineering, University of Alberta, Alberta, Canada
    Magn Reson Med 54:1305-10. 2005
    ..Images were acquired in 11.1 min with a voxel size of 0.25 cm3 and the SNR in CSF, which is typically approximately 3 times larger than in brain, was reduced to 23% of that in the brain tissue, which had an average SNR of 17...
  39. ncbi request reprint Voxel based versus region of interest analysis in diffusion tensor imaging of neurodevelopment
    Lindsay Snook
    Department of Biomedical Engineering, 1098 Research Transition Facility, University of Alberta, Edmonton, AB, Canada T6G 2V2
    Neuroimage 34:243-52. 2007
    ..These two analysis methods for DTI offer complementary results, but neither one yields the complete story of neurodevelopment...
  40. ncbi request reprint In vivo magnetic resonance imaging of the human cervical spinal cord at 3 Tesla
    Jeffrey R Korzan
    Department of Biomedical Engineering, University of Alberta, Edmonton, Canada
    J Magn Reson Imaging 16:21-7. 2002
    ....
  41. doi request reprint Brain diffusion abnormalities in children with fetal alcohol spectrum disorder
    Catherine Lebel
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Alcohol Clin Exp Res 32:1732-40. 2008
    ..The purpose of this study was to use diffusion tensor imaging, an advanced magnetic resonance imaging technique, to examine microstructural differences of white and deep gray matter in children with FASD...
  42. doi request reprint Advantage of sampling density weighted apodization over postacquisition filtering apodization for sodium MRI of the human brain
    Robert Stobbe
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Magn Reson Med 60:981-6. 2008
    ....
  43. ncbi request reprint Diffusion tensor imaging detects early Wallerian degeneration of the pyramidal tract after ischemic stroke
    Gotz Thomalla
    Klinik und Poliklinik fur Neurologie, Universitatsklinikum Hamburg Eppendorf, Hamburg, Germany
    Neuroimage 22:1767-74. 2004
    ..We demonstrated for the first time a correlation of early DTI findings of pyramidal tract damage with the motor deficit. DTI can help prognosing recovery of motor function after stroke within the early subacute phase...
  44. ncbi request reprint Combined X-ray angiography and diffusion-perfusion MRI for studying stroke evolution after rt-PA treatment in rats
    Elmar Busch
    Department of Neurology, University of Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Brain Res 953:112-8. 2002
    ..4+/-5.4 versus 47.7+/-17.9% of ipsilateral hemisphere, P=0.042). Our results demonstrate that the combination of angiography and MR-imaging is useful to further evaluate rt-PA treatment of thromboembolic stroke...