W S Beattie

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint A meta-analytic comparison of preoperative stress echocardiography and nuclear scintigraphy imaging
    W Scott Beattie
    Department of Anesthesia and Pain Management University Health Network Toronto General Hospital, University of Toronto, Toronto, Ontario
    Anesth Analg 102:8-16. 2006
  2. ncbi request reprint Epidural analgesia reduces postoperative myocardial infarction: a meta-analysis
    W S Beattie
    Department of Anesthesia, McMaster University, Hamilton, Ontario, Canada
    Anesth Analg 93:853-8. 2001
  3. doi request reprint Does tight heart rate control improve beta-blocker efficacy? An updated analysis of the noncardiac surgical randomized trials
    W Scott Beattie
    Department of Anesthesia, Toronto General Hospital and University of Toronto, EN 3 450 200 Elizabeth St, Toronto, Ontario M5G 2C4, Canada
    Anesth Analg 106:1039-48, table of contents. 2008
  4. doi request reprint Acute surgical anemia influences the cardioprotective effects of beta-blockade: a single-center, propensity-matched cohort study
    W Scott Beattie
    Department of Health Policy Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
    Anesthesiology 112:25-33. 2010
  5. doi request reprint Risk associated with preoperative anemia in noncardiac surgery: a single-center cohort study
    W Scott Beattie
    Department of Anesthesia, University Health Network, Toronto General Hospital, Toronto, Ontario, Canada
    Anesthesiology 110:574-81. 2009
  6. ncbi request reprint Evaluating surrogate measures of renal dysfunction after cardiac surgery
    Duminda N Wijeysundera
    Department of Anaesthesia, University of Toronto, Ontario, Canada
    Anesth Analg 96:1265-73, table of contents. 2003
  7. doi request reprint Outcomes and processes of care related to preoperative medical consultation
    Duminda N Wijeysundera
    Institute for Clinical Evaluative Sciences, Keenan Research Centre, Li Ka Shing Knowledge Institute of St Michael s Hospital, Department of Anesthesia, Toronto General Hospital and University of Toronto, EN 3 450, 200 Elizabeth St, Toronto, ON M5G 2C4, Canada
    Arch Intern Med 170:1365-74. 2010
  8. ncbi request reprint Recombinant factor VIIa for intractable blood loss after cardiac surgery: a propensity score-matched case-control analysis
    Keyvan Karkouti
    Department of Anesthesia, University of Toronto, University Health Network, Toronto, Ontario, Canada
    Transfusion 45:26-34. 2005
  9. ncbi request reprint Calcium antagonists are associated with reduced mortality after cardiac surgery: a propensity analysis
    Duminda N Wijeysundera
    Department of Anesthesia, University of Toronto, EN 3 453, Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada
    J Thorac Cardiovasc Surg 127:755-62. 2004
  10. doi request reprint Systematic review: prediction of perioperative cardiac complications and mortality by the revised cardiac risk index
    Meredith K Ford
    Toronto General Hospital and University of Toronto, Toronto, Ontario, Canada
    Ann Intern Med 152:26-35. 2010

Detail Information

Publications61

  1. ncbi request reprint A meta-analytic comparison of preoperative stress echocardiography and nuclear scintigraphy imaging
    W Scott Beattie
    Department of Anesthesia and Pain Management University Health Network Toronto General Hospital, University of Toronto, Toronto, Ontario
    Anesth Analg 102:8-16. 2006
    ..A moderate-to-large perfusion defect by either SE or TI predicts postoperative MI and death. We conclude the SE is superior to TI in predicting postoperative cardiac events...
  2. ncbi request reprint Epidural analgesia reduces postoperative myocardial infarction: a meta-analysis
    W S Beattie
    Department of Anesthesia, McMaster University, Hamilton, Ontario, Canada
    Anesth Analg 93:853-8. 2001
    ..3%; 95% CI, -3.8%, 1.2%, P = 0.091). Subgroup analysis of postoperative thoracic epidural analgesia showed a significant reduction in PMI in the Epidural group (rate difference, -5.3%; 95% CI, -9.9%, -0.7%; P = 0.04)...
  3. doi request reprint Does tight heart rate control improve beta-blocker efficacy? An updated analysis of the noncardiac surgical randomized trials
    W Scott Beattie
    Department of Anesthesia, Toronto General Hospital and University of Toronto, EN 3 450 200 Elizabeth St, Toronto, Ontario M5G 2C4, Canada
    Anesth Analg 106:1039-48, table of contents. 2008
    ..Tight control of heart rate (HR) has been suggested to improve these outcomes. Meta-analyses have not considered the influence of tight HR control on the efficacy of perioperative beta-blockade...
  4. doi request reprint Acute surgical anemia influences the cardioprotective effects of beta-blockade: a single-center, propensity-matched cohort study
    W Scott Beattie
    Department of Health Policy Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
    Anesthesiology 112:25-33. 2010
    ....
  5. doi request reprint Risk associated with preoperative anemia in noncardiac surgery: a single-center cohort study
    W Scott Beattie
    Department of Anesthesia, University Health Network, Toronto General Hospital, Toronto, Ontario, Canada
    Anesthesiology 110:574-81. 2009
    ..The objective of this observational study was to measure the prevalence of preoperative anemia and assess the relationship between preoperative anemia and postoperative mortality...
  6. ncbi request reprint Evaluating surrogate measures of renal dysfunction after cardiac surgery
    Duminda N Wijeysundera
    Department of Anaesthesia, University of Toronto, Ontario, Canada
    Anesth Analg 96:1265-73, table of contents. 2003
    ..Mathematical transformation of DeltaCr(72h) to %DeltaCrCl(72h) results in a normal distribution that is amenable to parametric statistical tests. DeltaCr(72h) and %DeltaCrCl(72h) may be used as surrogate outcomes in future trials...
  7. doi request reprint Outcomes and processes of care related to preoperative medical consultation
    Duminda N Wijeysundera
    Institute for Clinical Evaluative Sciences, Keenan Research Centre, Li Ka Shing Knowledge Institute of St Michael s Hospital, Department of Anesthesia, Toronto General Hospital and University of Toronto, EN 3 450, 200 Elizabeth St, Toronto, ON M5G 2C4, Canada
    Arch Intern Med 170:1365-74. 2010
    ..Nonetheless, the impact of these consultations, which may be performed by general internists or specialists, on outcomes is unclear...
  8. ncbi request reprint Recombinant factor VIIa for intractable blood loss after cardiac surgery: a propensity score-matched case-control analysis
    Keyvan Karkouti
    Department of Anesthesia, University of Toronto, University Health Network, Toronto, Ontario, Canada
    Transfusion 45:26-34. 2005
    ..Recombinant factor VIIa (rF-VIIa) is being increasingly used as rescue therapy in such cases, but little information is available on its safety and efficacy for this indication...
  9. ncbi request reprint Calcium antagonists are associated with reduced mortality after cardiac surgery: a propensity analysis
    Duminda N Wijeysundera
    Department of Anesthesia, University of Toronto, EN 3 453, Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada
    J Thorac Cardiovasc Surg 127:755-62. 2004
    ..We therefore performed a prospective observational cohort study of the effects of calcium channel blockers on cardiac surgical mortality. A propensity score technique was used for risk adjustment...
  10. doi request reprint Systematic review: prediction of perioperative cardiac complications and mortality by the revised cardiac risk index
    Meredith K Ford
    Toronto General Hospital and University of Toronto, Toronto, Ontario, Canada
    Ann Intern Med 152:26-35. 2010
    ..The Revised Cardiac Risk Index (RCRI) is widely used to predict perioperative cardiac complications...
  11. ncbi request reprint Aprotinin is useful as a hemostatic agent in cardiopulmonary surgery: no
    K Karkouti
    Department of Anesthesia, Health Network, University of Toronto, Toronto, ON, Canada
    J Thromb Haemost 4:1879-81. 2006
  12. ncbi request reprint The effects of a treatment protocol for cardiac surgical patients with excessive blood loss on clinical outcomes
    K Karkouti
    Department of Anaesthesia, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Vox Sang 91:148-56. 2006
    ..The objective of this before/after study was to determine whether the implementation of a protocol for management of cardiac surgical patients with EBL was associated with improved clinical outcomes...
  13. ncbi request reprint Variability and predictability of large-volume red blood cell transfusion in cardiac surgery: a multicenter study
    Keyvan Karkouti
    University Health Network, Toronto General Hospital, Department of Anesthesia, Ontario, Canada
    Transfusion 47:2081-8. 2007
    ..The objectives of this study were to measure the interinstitution variation and predictability of large-volume RBC transfusion...
  14. ncbi request reprint The role of recombinant factor VIIa in on-pump cardiac surgery: proceedings of the Canadian Consensus Conference
    Keyvan Karkouti
    University Health Network, Toronto General Hospital, Department of Anesthesia, Toronto, Ontario, Canada
    Can J Anaesth 54:573-82. 2007
    ..A Canadian Consensus Conference was convened to generate recommendations for rFVIIa use in on-pump cardiac surgery...
  15. ncbi request reprint N-acetylcysteine for preventing acute kidney injury in cardiac surgery patients with pre-existing moderate renal insufficiency
    Duminda N Wijeysundera
    Department of Anesthesia, Toronto General Hospital and University of Toronto, EN 3 450, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada
    Can J Anaesth 54:872-81. 2007
    ..To determine if N-acetylcysteine warrants definitive evaluation in a large multicentre trial, we evaluated its effects on a surrogate outcome, estimated glomerular filtration rate (eGFR), in a randomized trial...
  16. doi request reprint Risk associated with preoperative anemia in cardiac surgery: a multicenter cohort study
    Keyvan Karkouti
    Department of Anesthesia, University Health Network, University of Toronto, Toronto, Ontario, Canada, M5G 2C4
    Circulation 117:478-84. 2008
    ..Whether preoperative anemia also is an independent risk factor for adverse outcomes after cardiac surgery, however, has not been fully elucidated...
  17. ncbi request reprint Derivation and validation of a simplified predictive index for renal replacement therapy after cardiac surgery
    Duminda N Wijeysundera
    Department of Anesthesia, Toronto General Hospital and University of Toronto, Toronto, Ontario, Canada
    JAMA 297:1801-9. 2007
    ..A predictive index for renal replacement therapy (RRT; hemodialysis or continuous venovenous hemodiafiltration) after cardiac surgery may improve clinical decision making and research design...
  18. doi request reprint The influence of baseline hemoglobin concentration on tolerance of anemia in cardiac surgery
    Keyvan Karkouti
    Department of Anesthesia, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Transfusion 48:666-72. 2008
    ..Nonetheless, "normal" Hb concentrations vary widely in the population, and this variability may influence patients' tolerance of acute anemia. This retrospective cohort study was carried out to test this hypothesis...
  19. doi request reprint Accelerated recovery from sevoflurane anesthesia with isocapnic hyperpnoea
    Rita Katznelson
    Department of Anesthesiology, Toronto General Hospital, Eaton North 3 453, 200 Elizabeth St, Toronto, ON M5G 2C4, Canada
    Anesth Analg 106:486-91, table of contents. 2008
    ..We studied the effect of IH on the emergence profile of sevoflurane-anesthetized patients by comparing postoperative recovery variables in patients administered IH (IH group) to those recovered in the customary fashion (control group)...
  20. doi request reprint Comprehensive Canadian review of the off-label use of recombinant activated factor VII in cardiac surgery
    Keyvan Karkouti
    University Health Network, Toronto General Hospital, Department of Anesthesia, EN 3 402, 200 Elizabeth St, Toronto, Ontario, Canada M5G 2C4
    Circulation 118:331-8. 2008
    ..This observational study sought to identify the off-label use pattern of recombinant activated factor VII (rFVIIa) in cardiac surgery and to identify predictors of its effectiveness and risk...
  21. doi request reprint N-acetylcysteine to reduce renal failure after cardiac surgery: a systematic review and meta-analysis
    Finola Naughton
    Department of Anesthesia and Pain Management, University Health Network, Toronto General Hospital, University of Toronto, Ontario, Canada
    Can J Anaesth 55:827-35. 2008
    ..To assess the effect of N-acetylcysteine (NAC) on acute renal failure and important clinical outcomes after cardiac surgery...
  22. doi request reprint Acute kidney injury after cardiac surgery: focus on modifiable risk factors
    Keyvan Karkouti
    Department of Anesthesia and Health Policy, Management, and Evaluation, Toronto General Hospital, University of Toronto, 200 Elizabeth St, EN 3 402, Toronto, Ontario, Canada M5G 2C4
    Circulation 119:495-502. 2009
    ..Lacking effective therapies, risk factor modification may offer a means of preventing this complication. The objective of the present study was to identify and determine the prognostic importance of such risk factors...
  23. doi request reprint Delirium following vascular surgery: increased incidence with preoperative beta-blocker administration
    Rita Katznelson
    Department of Anesthesia and Pain Management, University of Toronto, Toronto, ON, Canada
    Can J Anaesth 56:793-801. 2009
    ..To determine if there is an association between perioperative administration of beta-blockers and postoperative delirium in patients undergoing vascular surgery...
  24. doi request reprint The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery
    Keyvan Karkouti
    Department of Anesthesia, University of Toronto, and Toronto General Hospital, Toronto, ON, Canada M5G 2C4
    Anesth Analg 110:21-9. 2010
    ..It remains unclear whether its risk-benefit profile differs among low-, moderate-, and high-risk cardiac surgical patients...
  25. pmc Non-invasive cardiac stress testing before elective major non-cardiac surgery: population based cohort study
    Duminda N Wijeysundera
    Institute for Clinical Evaluative Sciences, Toronto, Ontario M4N 3M5, Canada
    BMJ 340:b5526. 2010
    ..To determine the association of non-invasive cardiac stress testing before elective intermediate to high risk non-cardiac surgery with survival and hospital stay...
  26. doi request reprint Hospital administrative database underestimates delirium rate after cardiac surgery
    Rita Katznelson
    Department of Anesthesiology, Toronto General Hospital, Eaton North 3 453, 200 Elizabeth Street, Toronto, ON M5G 2C4, Canada
    Can J Anaesth 57:898-902. 2010
    ....
  27. doi request reprint Preoperative use of statins is associated with reduced early delirium rates after cardiac surgery
    Rita Katznelson
    Dpartment of Anesthesia, Toronto General Hospital, University of Toronto, Toronto, Canada
    Anesthesiology 110:67-73. 2009
    ..The objective of this study was to determine an association between preoperative administration of statins and postoperative delirium in a large prospective cohort of patients undergoing cardiac surgery with cardiopulmonary bypass...
  28. ncbi request reprint Off-pump coronary artery surgery for reducing mortality and morbidity: meta-analysis of randomized and observational studies
    Duminda N Wijeysundera
    Department of Anesthesia, Toronto General Hospital, Toronto, Ontario, Canada
    J Am Coll Cardiol 46:872-82. 2005
    ..The purpose of this study was to assess the effects of off-pump coronary bypass surgery (OPCAB) on mortality and morbidity...
  29. ncbi request reprint Improving the identification of patients at risk of postoperative renal failure after cardiac surgery
    Duminda N Wijeysundera
    Department of Anesthesia, Toronto General Hospital and University of Toronto, Ontario, Canada
    Anesthesiology 104:65-72. 2006
    ..Calculated creatinine clearance (CrCl) is an alternative measure of renal function that may allow better estimation of renal reserve...
  30. ncbi request reprint Platelet transfusions are not associated with increased morbidity or mortality in cardiac surgery
    Keyvan Karkouti
    Department of Anesthesia, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Can J Anaesth 53:279-87. 2006
    ..To determine the independent relationship between leukoreduced platelet transfusions and adverse events in cardiac surgery...
  31. ncbi request reprint A propensity score case-control comparison of aprotinin and tranexamic acid in high-transfusion-risk cardiac surgery
    Keyvan Karkouti
    Department of Anesthesia, University of Toronto, Toronto, Ontario, Canada
    Transfusion 46:327-38. 2006
    ..Prophylactic use of the antifibrinolytic drugs aprotinin and tranexamic acid is thought to prevent these hemostatic defects. Their relative clinical utility and safety in high-transfusion-risk cardiac surgery, however, is not known...
  32. ncbi request reprint Prognostic value of postoperative proteinuria in cardiac surgery: a pilot study
    Keyvan Karkouti
    University Health Network, Toronto General Hospital, Department of Anesthesia, EN 3 402, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada
    Can J Anaesth 53:500-6. 2006
    ..The objective of this pilot study was to determine if postoperative proteinuria is associated with adverse outcomes following cardiac surgery with cardiopulmonary bypass...
  33. ncbi request reprint Alpha-2 adrenergic agonists to prevent perioperative cardiovascular complications: a meta-analysis
    Duminda N Wijeysundera
    Department of Anesthesia, University Health Network, Ontario, Toronto, Canada
    Am J Med 114:742-52. 2003
    ..To investigate the effects of alpha(2)-adrenergic agonists on perioperative mortality and cardiovascular complications in adults undergoing surgery...
  34. ncbi request reprint Calcium antagonists reduce cardiovascular complications after cardiac surgery: a meta-analysis
    Duminda N Wijeysundera
    Department of Anesthesia, University of Toronto, Toronto, Ontario, Canada
    J Am Coll Cardiol 41:1496-505. 2003
    ..We sought to determine the efficacy of calcium antagonists (CAs) in reducing death, myocardial infarction (MI), ischemia, and supraventricular tachyarrhythmia (SVT) after cardiac surgery...
  35. ncbi request reprint Regional anesthesia in cardiac surgery: a friend or a foe?
    George Djaiani
    Department of Anesthesiology, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Semin Cardiothorac Vasc Anesth 9:87-104. 2005
    ..A prospective, randomized, controlled multicenter trial needs to be adequately powered to answer important clinical questions and allow for a long-term follow-up...
  36. ncbi request reprint The independent association of massive blood loss with mortality in cardiac surgery
    Keyvan Karkouti
    Department of Anesthesia, University of Toronto, Toronto, Ontario, Canada
    Transfusion 44:1453-62. 2004
    ..The objective of this cohort study was to quantify the independent association of MBL in cardiac surgery with all-cause in-hospital mortality...
  37. ncbi request reprint Determinants of complications with recombinant factor VIIa for refractory blood loss in cardiac surgery
    Keyvan Karkouti
    University of Toronto, University Health Network, Department of Anesthesia, 3 Eaton North, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada
    Can J Anaesth 53:802-9. 2006
    ..Recombinant factor VIIa (rFVIIa) is being used for refractory, excessive blood loss (EBL) after cardiac surgery, but its safety for this indication is not known...
  38. ncbi request reprint Prediction of massive blood transfusion in cardiac surgery
    Keyvan Karkouti
    University Health Network, Toronto General Hospital, Department of Anesthesia, EN 3 402, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada
    Can J Anaesth 53:781-94. 2006
    ..The objective of this study was to develop a prediction rule for massive blood transfusion (MBT) that could be used to optimize the management of, and research on, at-risk patients...
  39. doi request reprint N-acetylcysteine is associated with increased blood loss and blood product utilization during cardiac surgery
    Duminda N Wijeysundera
    Department of Anesthesia, Toronto General Hospital and University of Toronto, Toronto, Ontario, Canada
    Crit Care Med 37:1929-34. 2009
    ..We, therefore, performed a post hoc analysis of a recent randomized controlled trial in cardiac surgery to determine whether N-acetylcysteine was associated with increased blood loss and blood product transfusion...
  40. pmc How strong is the evidence for the use of perioperative beta blockers in non-cardiac surgery? Systematic review and meta-analysis of randomised controlled trials
    P J Devereaux
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    BMJ 331:313-21. 2005
    ..To determine the effect of perioperative beta blocker treatment in patients having non-cardiac surgery...
  41. ncbi request reprint Calcium channel blockers for reducing cardiac morbidity after noncardiac surgery: a meta-analysis
    Duminda N Wijeysundera
    Department of Anesthesia, University of Toronto, ON
    Anesth Analg 97:634-41. 2003
    ..The majority of these benefits are attributable to diltiazem, suggesting the need for further evaluation of this drug in a large RCT...
  42. doi request reprint Epidural anaesthesia and survival after intermediate-to-high risk non-cardiac surgery: a population-based cohort study
    Duminda N Wijeysundera
    Department of Health Policy Management and Evaluation, University of Toronto, Toronto, ON, Canada
    Lancet 372:562-9. 2008
    ..We therefore undertook a population-based cohort study to determine whether perioperative epidural anaesthesia or analgesia is associated with improved 30-day survival...
  43. doi request reprint Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial
    P J Devereaux
    McMaster University, Faculty of Health Sciences, Clinical Epidemiology and Biostatistics, Room 2C8, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada
    Lancet 371:1839-47. 2008
    ..This randomised controlled trial, done in 190 hospitals in 23 countries, was designed to investigate the effects of perioperative beta blockers...
  44. pmc Aspirin "resistance" and risk of cardiovascular morbidity: systematic review and meta-analysis
    George Krasopoulos
    University Health Network, Division of Cardiovascular Surgery, Toronto General Hospital
    BMJ 336:195-8. 2008
    ..To determine if there is a relation between aspirin "resistance" and clinical outcomes in patients with cardiovascular disease...
  45. doi request reprint A population-based study of anesthesia consultation before major noncardiac surgery
    Duminda N Wijeysundera
    Department of Anesthesia, Toronto General Hospital and University of Toronto, ON, Canada
    Arch Intern Med 169:595-602. 2009
    ..Nonetheless, the impact of anesthesia consultation on outcomes in the population remains unclear...
  46. ncbi request reprint Nitrous oxide-induced increased homocysteine concentrations are associated with increased postoperative myocardial ischemia in patients undergoing carotid endarterectomy
    N H Badner
    Departments of Anesthesiology and Clinical Pharmacology, University of Western Ontario, London, Ontario, Canada
    Anesth Analg 91:1073-9. 2000
    ..Implications: Use of nitrous oxide during carotid artery surgery induces increases in postoperative plasma homocysteine concentration and is associated with increases in postoperative myocardial ischemia...
  47. ncbi request reprint Hemodilution during cardiopulmonary bypass is an independent risk factor for acute renal failure in adult cardiac surgery
    K Karkouti
    Department of Anesthesia, University Health Network, University of Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 129:391-400. 2005
    ..This observational study sought to determine whether the degree of hemodilution during cardiopulmonary bypass is independently related to perioperative acute renal failure necessitating dialysis support...
  48. doi request reprint Metoprolol reduces cerebral tissue oxygen tension after acute hemodilution in rats
    Tenille E Ragoonanan
    Department of Anesthesia, Keenan Research Centre of the Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Anesthesiology 111:988-1000. 2009
    ..This study investigated the effect of beta-blockade on cerebral tissue oxygen delivery in an experimental model of blood loss and fluid resuscitation (hemodilution)...
  49. doi request reprint A report of fulminant malignant hyperthermia in a patient with a novel mutation of the CACNA1S gene
    P Jason Toppin
    Department of Anesthesia and Pain Management, Toronto General Hospital, University of Toronto, ON, Canada
    Can J Anaesth 57:689-93. 2010
    ..To report the identification of a novel mutation in the CACNA1S gene that encodes the alpha-1-subunit (Cav1.1) of the voltage-gated skeletal muscle L-type calcium channel in a patient with malignant hyperthermia...
  50. doi request reprint Bayesian statistical inference enhances the interpretation of contemporary randomized controlled trials
    Duminda N Wijeysundera
    Department of Health Policy Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
    J Clin Epidemiol 62:13-21.e5. 2009
    ..Frequentist methods have limitations that might be overcome, in part, by Bayesian inference. To illustrate these advantages, we re-analyzed randomized trials published in four general medical journals during 2004...
  51. ncbi request reprint The effects of volatile anesthetics on cardiac ischemic complications and mortality in CABG: a meta-analysis
    Chun Hua Yu
    Department of Anesthesia, University Health Network, Toronto, ON, Canada
    Can J Anaesth 53:906-18. 2006
    ..Volatile anesthetics have been shown to have a preconditioning-like effect. This systematic review assesses the effects of volatile anesthetics on cardiac ischemic complications and morbidity after CABG...
  52. doi request reprint Development of an algorithm to identify preoperative medical consultations using administrative data
    Duminda N Wijeysundera
    Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
    Med Care 47:1258-64. 2009
    ..However, administrative data in many jurisdictions lack specific codes to identify preoperative medical consultations, as opposed to consultations for nonoperative indications...
  53. ncbi request reprint Con: Aprotinin has a good efficacy and safety profile relative to other alternatives for prevention of bleeding in cardiac surgery
    W Scott Beattie
    Anesth Analg 103:1360-4. 2006
  54. ncbi request reprint Best evidence in anesthetic practice: prevention: epidural anesthesia and analgesia does not reduce 30-day all-cause mortality and major morbidity after abdominal surgery
    Sugantha Ganapathy
    Can J Anaesth 50:143-6. 2003
  55. pmc The value of routine preoperative electrocardiography in predicting myocardial infarction after noncardiac surgery
    Wilton A van Klei
    University Medical Center Utrecht, Dept Perioperative Care and Emergency Medicine, Utrecht, The Netherlands
    Ann Surg 246:165-70. 2007
    ..The added value of a preoperative electrocardiogram (ECG) in the prediction of postoperative myocardial infarction (POMI) and death was compared with clinical risk factors identified from the patient's history...
  56. doi request reprint Letter by Karkouti and Beattie regarding article "Aprotinin does not increase the risk of renal failure in cardiac surgery patients"
    Keyvan Karkouti
    Circulation 117:e472; author reply e476. 2008
  57. ncbi request reprint An alternative view of current evidence in support of perioperative beta-blockers
    W Scott Beattie
    Arch Intern Med 165:347-8; author reply 349. 2005
  58. ncbi request reprint Platelet transfusions as a risk factor in cardiac surgery
    Keyvan Karkouti
    Transfusion 47:1739-40; author reply 1740. 2007
  59. ncbi request reprint Blood transfusions and mortality among critically ill patients
    Keyvan Karkouti
    JAMA 289:1242. 2003
  60. ncbi request reprint High-quality randomized trial of perioperative beta-blockade
    Duminda N Wijeysundera
    Am Heart J 153:e17; author reply e19. 2007
  61. ncbi request reprint Meta-analysis demonstrates statistically significant reduction in postoperative myocardial infarction with the use of thoracic epidural analgesia
    W Scott Beattie
    Anesth Analg 97:919-20. 2003