Research Topics
| Sean M BagshawSummaryAffiliation: University of Calgary Country: Canada Publications
| Collaborators
|
Detail Information
Publications
One-year mortality in critically ill patients by severity of kidney dysfunction: a population-based assessmentSean M Bagshaw
Department of Critical Care Medicine, Calgary Health Region and University of Calgary, Alberta, Canada
Am J Kidney Dis 48:402-9. 2006..Kidney dysfunction in the intensive care unit (ICU) results in increased morbidity, mortality, and health care costs; however, long-term mortality has not been described across strata of severity in kidney dysfunction...
Prognosis for long-term survival and renal recovery in critically ill patients with severe acute renal failure: a population-based studySean M Bagshaw
Department of Critical Care Medicine, Calgary Health Region, University of Calgary, Calgary, Alberta, Canada
Crit Care 9:R700-9. 2005..Severe acute renal failure (sARF) is associated with considerable morbidity, mortality and use of healthcare resources; however, its precise epidemiology and long-term outcomes have not been well described in a non-specified population...- Dialysis Disequilibrium Syndrome: brain death following hemodialysis for metabolic acidosis and acute renal failure--a case reportSean M Bagshaw
Department of Critical Care Medicine, Calgary Health Region, University of Calgary, Calgary, Alberta, Canada
BMC Nephrol 5:9. 2004..We describe a case of DDS-induced cerebral edema that resulted in irreversible brain injury and death following acute HD and review the relevant literature of the association of DDS and HD... 
A multi-center evaluation of early acute kidney injury in critically ill trauma patientsSean M Bagshaw
Division of Critical Care Medicine, Walter C Mackenzie Centre, University of Alberta Hospital, University of Alberta, Edmonton, Alberta, Canada
Ren Fail 30:581-9. 2008..Few studies have evaluated the epidemiology of acute kidney injury (AKI) in trauma...- A prospective evaluation of urine microscopy in septic and non-septic acute kidney injurySean M Bagshaw
Division of Critical Care Medicine, University of Alberta Hospital, University of Alberta, Alberta, Canada
Nephrol Dial Transplant 27:582-8. 2012..Sepsis is the most common trigger for acute kidney injury (AKI) in critically ill patients. We sought to determine whether there are unique patterns to urine sediment in septic compared with non-septic AKI... - Early blood glucose control and mortality in critically ill patients in AustraliaSean M Bagshaw
Division of Critical Care Medicine, University of Alberta Hospital, University of Alberta, Edmonton, Alberta, Canada
Crit Care Med 37:463-70. 2009..To measure temporal trends in blood glucose (BG) control and describe their association with hospital mortality in a cohort of critically ill patients from Australia... 
The impact of early hypoglycemia and blood glucose variability on outcome in critical illnessSean M Bagshaw
Division of Critical Care Medicine, University of Alberta Hospital, University of Alberta, 8440 112 ST NW Edmonton, Alberta, Canada
Crit Care 13:R91. 2009..We describe the incidence, clinical factors and outcomes associated with an early hypoglycemia and BG variability in critically ill patients...- The SPARK Study: a phase II randomized blinded controlled trial of the effect of furosemide in critically ill patients with early acute kidney injurySean M Bagshaw
Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 12 Walter C, Mackenzie Centre, 8440 112 Street, Edmonton, Alberta, Canada
Trials 11:50. 2010..The primary analysis will be intention-to-treat. Planned recruitment will be complete by June 2011 and results available by December 2011. TRIAL REGISTRATION: ClinicalTrials.gov Identifier NCT00978354... - Intensive care unit-acquired urinary tract infections in a regional critical care systemKevin B Laupland
Department of Critical Care Medicine, Center for Anti microbial Resistance, Calgary Health Region, Calgary Laboratory Services, and University of Calgary, Calgary, Alberta, Canada
Crit Care 9:R60-5. 2005..The objectives of this study were to describe the occurrence, microbiology, and risk factors for acquiring UTIs in the ICU and to determine whether these infections independently increase mortality... - One-year mortality of bloodstream infection-associated sepsis and septic shock among patients presenting to a regional critical care systemKevin B Laupland
Department of Critical Care Medicine, University of Calgary, 3535 Research Road NW, Calgary, AB, T2L 2K8, Canada
Intensive Care Med 31:213-9. 2005.... - Intraoperative renal support during liver transplantationDerek R Townsend
Division of Critical Care Medicine, University of Alberta Hospital, University of Alberta, Edmonton, Alberta, Canada
Liver Transpl 15:73-8. 2009..In conclusion, our data suggest that intraoperative CRRT during OLT is achievable and safe. Intraoperative CRRT may be a valuable adjuvant therapy for those with preoperative AKI. Additional investigations are warranted... - Oliguria, volume overload, and loop diureticsSean M Bagshaw
Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
Crit Care Med 36:S172-8. 2008..This contradiction between clinical practice and available evidence would suggest there is equipoise and need for higher-quality evidence to better characterize the role of loop diuretics in ICU patients with AKI... - Continuous versus intermittent renal replacement therapy for critically ill patients with acute kidney injury: a meta-analysisSean M Bagshaw
Division of Critical Care Medicine, University of Alberta Hospital, University of Alberta, Edmonton, Alberta, Canada
Crit Care Med 36:610-7. 2008..To appraise the literature on the effect of initial renal replacement therapy (RRT) modality on clinical outcomes... - Epidemiology of intensive care unit-acquired urinary tract infectionsSean M Bagshaw
Department of Critical Care Medicine, Calgary Laboratory Services, Calgary Health Region, and University of Calgary, Calgary, Alberta, Canada
Curr Opin Infect Dis 19:67-71. 2006..There is a relative paucity of research on nosocomial urinary tract infection specifically acquired in the intensive care unit and further studies are needed to better define the epidemiology and management of these infections... - The role of the medical emergency team in end-of-life care: a multicenter, prospective, observational studyDaryl A Jones
Division of Critical Care Medicine, University of Alberta, University of Alberta Hospital, Edmonton, Alberta, Canada
Crit Care Med 40:98-103. 2012..To investigate the role of medical emergency teams in end-of-life care planning... - Prolonged refractory status epilepticus following acute traumatic brain injury: a case report of excellent neurological recoveryAdam D Peets
Department of Critical Care, University of Calgary, Calgary, Alberta, Canada
Crit Care 9:R725-8. 2005..Refractory status epilepticus (RSE) secondary to traumatic brain injury (TBI) may be under-recognized and is associated with significant morbidity and mortality... - Blood glucose control among critically ill patients with brain injuryMichael J Jacka
Department of Anaesthesiology and Pain Medicine, Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
Can J Neurol Sci 36:436-42. 2009..To evaluate the incidence of hypoglycemia, hyperglycemia and blood glucose (BG) variability in brain-injured patients and their association with clinical outcomes... - Acetylcysteine in the prevention of contrast-induced nephropathy: a case study of the pitfalls in the evolution of evidenceSean M Bagshaw
Department of Critical Care Medicine, University of Calgary, Calgary, Alberta, Canada
Arch Intern Med 166:161-6. 2006.... - Is regional citrate superior to systemic heparin anticoagulation for continuous renal replacement therapy? A prospective observational study in an adult regional critical care systemSean M Bagshaw
Department of Critical Care Medicine, University of Calgary and Calgary Health Region, Foothills Medical Centre, Alberta, Canada
J Crit Care 20:155-61. 2005..We report our regional CRRT protocol that was developed using the principles of quality improvement and compare the effect of regional citrate with systemic heparin anticoagulation on filter life span... - Association between implementation of an intensivist-led medical emergency team and mortalityConstantine J Karvellas
Division of Critical Care Medicine, University of Alberta Hospital, Edmonton, Alberta, Canada
BMJ Qual Saf 21:152-9. 2012..To evaluate the impact of implementation of a dedicated intensivist-led medical emergency team (IL-MET) on mortality in patients admitted to the intensive care unit (ICU)... - Intensive care unit bed availability and outcomes for hospitalized patients with sudden clinical deteriorationHenry T Stelfox
Department of Critical Care Medicine, University of Calgary, Teaching, Research and Wellness Building, 3280 Hospital Dr NW, Calgary, AB, Canada
Arch Intern Med 172:467-74. 2012..We evaluated the effect of ICU bed availability on processes and outcomes of care for hospitalized patients with sudden clinical deterioration... - Best evidence in critical care medicine. Steroids to prevent post-extubation airway obstruction in adult critically ill patientsSean M Bagshaw
University of Alberta Hospital, University of Alberta, Edmonton, Alberta, Canada
Can J Anaesth 55:382-5. 2008 - Early diagnosis of acute kidney injury in critically ill patientsRobert Keyes
Division of Critical Care Medicine, University of Alberta Hospital, University of Alberta, Edmonton, Alberta, Canada
Expert Rev Mol Diagn 8:455-64. 2008..This article will review the pitfalls of current conventional testing in kidney injury and discuss the emergence of novel biomarkers with the potential to revolutionize the field of critical care nephrology... - Prophylactic amiodarone for prevention of atrial fibrillation after cardiac surgery: a meta-analysisSean M Bagshaw
Department of Critical Care Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada; Department of Intensive Care, Austin Hospital, Melbourne, Victoria, Australia
Ann Thorac Surg 82:1927-37. 2006..The current evidence supports recommending the routine use of perioperative amiodarone for cardiac surgery... - The influence of volume management on outcomeSean M Bagshaw
Division of Critical Care Medicine, University of Alberta Hospital, University of Alberta, Edmonton, Alberta, Canada
Curr Opin Crit Care 13:541-8. 2007..There is much controversy, however, about the type, timing and amount of fluid therapy. Here, we discuss the evidence available to guide such choices... - Blood cytokine, chemokine and gene expression in cholestasis patients with intractable pruritis treated with a molecular adsorbent recirculating system: a case seriesLuiz F Lisboa
Transplant Infectious Diseases, University of Alberta, Edmonton, Alberta, Canada
Can J Gastroenterol 26:799-805. 2012..The molecular adsorbent recirculating system (MARS) is an albumin-dialysis modality that has been investigated predominantly in patients with acute and acute-on-chronic liver failure... - Prolonging life and delaying death: the role of physicians in the context of limited intensive care resourcesRobert C McDermid
Division of Critical Care Medicine, University of Alberta Hospital, University of Alberta, Edmonton, Alberta, Canada
Philos Ethics Humanit Med 4:3. 2009.... - Conventional markers of kidney functionSean M Bagshaw
Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
Crit Care Med 36:S152-8. 2008.... - Tension pneumothorax secondary to colonic perforation during diagnostic colonoscopy: report of a caseChad G Ball
Department of Surgery, Foothills Medical Centre, Room EG23, 1403 - 29 Street NW, Calgary, Alberta, T2N 2T9, Canada
Surg Today 36:478-80. 2006..Both of these conditions should be considered in the event of acute respiratory failure in the endoscopy suite... - Theophylline for prevention of contrast-induced nephropathy: a systematic review and meta-analysisSean M Bagshaw
Department of Critical Care Medicine, Calgary Health Region, and Departments of Internal Medicine, University of Calgary, Calgary, Alberta, Canada
Arch Intern Med 165:1087-93. 2005..However, findings are inconsistent across studies. A large, well-designed trial that incorporates the evaluation of clinically relevant outcomes is required to more adequately assess the role for theophylline in CIN prevention... - Urinary biomarkers in septic acute kidney injurySean M Bagshaw
Division of Critical Care Medicine, University of Alberta Hospital, 3C1 16 Walter C Mackenzie Centre, 8440 112 Street, T6G 2B7, Edmonton, Alberta, Canada
Intensive Care Med 33:1285-96. 2007..To appraise the literature on the value of urinary biomarkers in septic acute kidney injury (AKI)... - Acetylcysteine for prevention of contrast-induced nephropathy after intravascular angiography: a systematic review and meta-analysisSean M Bagshaw
Department of Critical Care Medicine, Calgary Health Region, Calgary, Canada
BMC Med 2:38. 2004..Contrast-induced nephropathy is an important cause of acute renal failure. We assess the efficacy of acetylcysteine for prevention of contrast-induced nephropathy among patients undergoing intravascular angiography... - Drug-induced rash with eosinophilia and systemic symptoms syndrome with bupropion administrationSean M Bagshaw
Department of Medicine, Foothills Medical Centre, University of Calgary, Calgary, Alberta, Canada
Ann Allergy Asthma Immunol 90:572-5. 2003..We report this case to notify clinicians of the potential serious multisystem complications that can occur with sustained-release bupropion therapy... - Urinary biochemistry and microscopy in septic acute renal failure: a systematic reviewSean M Bagshaw
Department of Intensive Care, Austin Hospital, Heidelberg, Victoria 3084, Australia
Am J Kidney Dis 48:695-705. 2006..More research is required to describe their accuracy, pattern, and time course in patients with septic ARF... - Renal support in critically ill patients with acute kidney injurySean M Bagshaw
N Engl J Med 359:1960-1. 2008 - Early acute kidney injury and sepsis: a multicentre evaluationSean M Bagshaw
Division of Critical Care Medicine, Faculty of Medicine and Dentistry, 3C1, 12 Walter C Mackenzie Centrel, University of Alberta Hospital, University of Alberta, 8440 112 St NW, Edmonton, Alberta, T6G2B7 Canada
Crit Care 12:R47. 2008..We conducted a study to evaluate the incidence, risk factors and outcomes associated with early acute kidney injury (AKI) in sepsis... - The long-term outcome after acute renal failureSean M Bagshaw
Department of Intensive Care, Austin Hospital, Melbourne, Australia
Curr Opin Crit Care 12:561-6. 2006..Research priorities in critical care are increasingly focusing on long-term outcomes and prognosis for survivors of critical illness. This review will focus on long-term outcomes after acute renal failure... - A comparison of the RIFLE and AKIN criteria for acute kidney injury in critically ill patientsSean M Bagshaw
Department of Intensive Care, Austin Hospital, Heidelberg, Victoria 3084, Australia
Nephrol Dial Transplant 23:1569-74. 2008..The Acute Kidney Injury Network (AKIN) group has recently proposed modifications to this system. It is currently unknown whether there are advantages between these criteria... - A multi-centre evaluation of the RIFLE criteria for early acute kidney injury in critically ill patientsSean M Bagshaw
Division of Critical Care Medicine, University of Alberta Hospital, 3C1 16 Walter C Mackenzie Centre, 8440 122 Street, Edmonton, Alberta T6G2B7, Canada
Nephrol Dial Transplant 23:1203-10. 2008..We sought to evaluate the RIFLE criteria on the day of ICU admission in a large heterogenous population of critically ill patients... - Loop diuretics in the management of acute renal failure: a systematic review and meta-analysisSean M Bagshaw
Department of Intensive Care, Austin Hospital, Melbourne, Vic, Australia
Crit Care Resusc 9:60-8. 2007..We systematically reviewed the literature comparing loop diuretics with control in the management of ARF... - Changes in the incidence and outcome for early acute kidney injury in a cohort of Australian intensive care unitsSean M Bagshaw
Division of Critical Care Medicine, University of Alberta Hospital, Edmonton, Canada
Crit Care 11:R68. 2007..There is limited information on whether the incidence of acute kidney injury (AKI) in critically ill patients has changed over time and there is controversy on whether its outcome has improved... - Septic acute kidney injury in critically ill patients: clinical characteristics and outcomesSean M Bagshaw
Department of Intensive Care and Department of Medicine, Austin and Repatriation Medical Centre, Melbourne, Australia
Clin J Am Soc Nephrol 2:431-9. 2007..Patients with septic AKI had an increased risk for death and longer duration of hospitalization yet showed trends toward greater renal recovery and independence from RRT... - The histopathology of septic acute kidney injury: a systematic reviewChristoph Langenberg
Department of Intensive Care, Austin Hospital, Studley Rd, Heidelberg, Melbourne, Victoria 3084, Australia
Crit Care 12:R38. 2008..Accordingly, we systematically reviewed the literature to assess current knowledge on the histopathology of septic AKI... - Is there a place for levosimendan in the intensive care unit?Anthony Delaney
Northern Clinical School, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia
Crit Care Resusc 9:290-2. 2007..Until their results can be fully scrutinised, and placed in the context of all available evidence, we should conclude that there is no place for levosimendan in the ICU... - Erythropoietin and transfusions among critically ill patientsSean M Bagshaw
JAMA 289:1511; author reply 1512. 2003 - Percutaneous dilatational tracheostomy versus surgical tracheostomy in critically ill patients: a systematic review and meta-analysisAnthony Delaney
Intensive Care Unit, Royal North Shore Hospital, Sydney, NSW, Australia
Crit Care 10:R55. 2006.... - Cardiopulmonary bypass-associated acute kidney injury: a pigment nephropathy?Michael Haase
Department of Intensive Care, Austin Health, Austin Hospital, Melbourne, Vic, Australia, and Department of Nephrology, Charite University Medicine, Berlin, Germany
Contrib Nephrol 156:340-53. 2007..A trial of such treatment might be a reasonable future investigation in higher risk patients receiving CPB... - Diuretics in the management of acute kidney injury: a multinational surveySean M Bagshaw
Division of Critical Care Medicine, University of Alberta Hospital, University of Alberta, Edmonton, Alta, Canada
Contrib Nephrol 156:236-49. 2007..Diuretics are a common intervention in critically ill patients with acute kidney injury (AKI). However, there is no information that describes the practice patterns of diuretic use by clinicians... - Urinary biochemistry in experimental septic acute renal failureChristoph Langenberg
Department of Intensive Care, Austin and Repatriation Medical Centre, Heidelberg, Victoria 3084, Australia
Nephrol Dial Transplant 21:3389-97. 2006..Despite increased renal perfusion, UNa, FeNa and FeUn decreased significantly. Our findings suggest that, in sepsis, these urinary biochemical changes are not reliable markers of renal hypoperfusion... - Early diagnosis of acute kidney injurySean M Bagshaw
Division of Critical Care Medicine, University of Alberta Hospital, University of Alberta, Edmonton, Canada
Curr Opin Crit Care 13:638-44. 2007..The early detection of acute kidney injury may allow for timely preventive or therapeutic measures. This review discusses the role of traditional and novel biomarkers in early acute kidney injury diagnosis... - Phase II, randomized, controlled trial of high-dose N-acetylcysteine in high-risk cardiac surgery patientsMichael Haase
Department of Intensive Care, Austin Hospital, University of Melbourne, Australia
Crit Care Med 35:1324-31. 2007..To assess the effect of high-dose N-acetylcysteine on renal function in cardiac surgery patients at higher risk of postoperative renal failure... - Pathophysiology of septic acute kidney injury: what do we really know?Li Wan
Department of Intensive Care, Austin Hospital, Melbourne, Australia
Crit Care Med 36:S198-203. 2008..If this were to happen, our therapeutic approaches would also be profoundly altered... - Epidemiology of renal recovery after acute renal failureSean M Bagshaw
Department of Intensive Care, Austin Hospital, Melbourne, Australia
Curr Opin Crit Care 12:544-50. 2006..Herein, the epidemiology of renal recovery after acute renal failure will be described, along with potential predictive factors and interventions... - Short- and long-term survival after acute kidney injurySean M Bagshaw
Nephrol Dial Transplant 23:2126-8. 2008 - Fluid resuscitation and the septic kidneySean M Bagshaw
Curr Opin Crit Care 12:527-30. 2006..Thus, in this editorial, we consider the relevant literature and more recent insights into the effect of fluid resuscitation on the septic kidney... - Caterpillar-induced bleeding syndrome in a returning travellerKris Chan
Department of Internal Medicine, University of Alberta, Edmonton, Alberta
CMAJ 179:158-61. 2008 - N-Acetylcysteine does not artifactually lower plasma creatinine concentrationMichael Haase
Director of Intensive Care Research, Austin Hospital, University of Melbourne, 3084 Heidelberg, Victoria, Australia
Nephrol Dial Transplant 23:1581-7. 2008..However, it has been suggested that NAC may lower plasma creatinine levels independent of any effects on glomerular filtration rate (GFR)... - Normotensive ischemic acute renal failureRinaldo Bellomo
N Engl J Med 357:2205; author reply 2205-6. 2007 - A systematic review of urinary findings in experimental septic acute renal failureSean M Bagshaw
Division of Critical Care Medicine, University of Alberta Hospital, University of Alberta, Edmonton, AB, Canada
Crit Care Med 35:1592-8. 2007..However, the scientific basis for such use has not been systematically evaluated. Thus, we appraised the value of common urinary findings for the diagnosis and classification of experimental septic acute renal failure...