Ildiko Badea

Summary

Affiliation: University of Saskatchewan
Country: Canada

Publications

  1. ncbi Evaluation of cellular uptake and intracellular trafficking as determining factors of gene expression for amino acid-substituted gemini surfactant-based DNA nanoparticles
    Jagbir Singh
    College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Canada
    J Nanobiotechnology 10:7. 2012
  2. ncbi Amino acid-substituted gemini surfactant-based nanoparticles as safe and versatile gene delivery agents
    Jagbir Singh
    Drug Design and Discovery Research Group, College of Pharmacy and Nutrition, University of Saskatchewan, Canada
    Curr Drug Deliv 8:299-306. 2011
  3. ncbi Design and evaluation of cyclodextrin-based delivery systems to incorporate poorly soluble curcumin analogs for the treatment of melanoma
    Deborah Michel
    Drug Design and Discovery Research Group, University of Saskatchewan, Saskatoon, Canada
    Eur J Pharm Biopharm 81:548-56. 2012
  4. ncbi DNA delivery for vaccination and therapeutics through the skin
    Marianna Foldvari
    College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Sask, Canada
    Curr Drug Deliv 3:17-28. 2006
  5. ncbi Gene delivery into human skin in vitro using biphasic lipid vesicles
    Marianna Foldvari
    College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK S7N 5C9, Canada
    Curr Drug Deliv 3:89-93. 2006
  6. ncbi In vivo cutaneous interferon-gamma gene delivery using novel dicationic (gemini) surfactant-plasmid complexes
    Ildiko Badea
    College of Pharmacy and Nutrition, University of Saskatchewan, SK. S7N 5C9, Canada
    J Gene Med 7:1200-14. 2005
  7. ncbi Topical non-invasive gene delivery using gemini nanoparticles in interferon-gamma-deficient mice
    Ildiko Badea
    College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada
    Eur J Pharm Biopharm 65:414-22. 2007
  8. ncbi Study on protein conformation and adsorption behaviors in nanodiamond particle-protein complexes
    Hai Dong Wang
    Department of Biomedical Engineering, University of Saskatchewan, Saskatoon S7N5A9, Canada
    Nanotechnology 22:145703. 2011
  9. ncbi Tandem mass spectrometric analysis of novel diquaternary ammonium gemini surfactants and their bromide adducts in electrospray-positive ion mode ionization
    Joshua Buse
    College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada
    J Mass Spectrom 46:1060-70. 2011
  10. ncbi Enhanced gene expression in epithelial cells transfected with amino acid-substituted gemini nanoparticles
    Peng Yang
    Department of Chemistry, University of Saskatchewan, Saskatoon, Canada
    Eur J Pharm Biopharm 75:311-20. 2010

Collaborators

  • M Foldvari
  • Anas El-Aneed
  • S Babiuk
  • Jagbir Singh
  • Deborah Michel
  • Ronald E Verrall
  • Peng Yang
  • Jackson M Chitanda
  • Joshua Buse
  • Hai Dong Wang
  • Martin J King
  • Réka Balogh
  • Umashankar Das
  • Ronald Verrall
  • Jonathan Dimmock
  • Catherine Hui Niu
  • Qiaoqin Yang
  • Shawn Wettig
  • Praveen Kumar
  • Kimberly J Gaspar
  • Jason Solomon

Detail Information

Publications11

  1. ncbi Evaluation of cellular uptake and intracellular trafficking as determining factors of gene expression for amino acid-substituted gemini surfactant-based DNA nanoparticles
    Jagbir Singh
    College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Canada
    J Nanobiotechnology 10:7. 2012
    ..In this study, we evaluated the mechanism of cellular uptake of the plasmid/gemini surfactant/helper lipid nanoparticles and their effect on the transfection efficiency...
  2. ncbi Amino acid-substituted gemini surfactant-based nanoparticles as safe and versatile gene delivery agents
    Jagbir Singh
    Drug Design and Discovery Research Group, College of Pharmacy and Nutrition, University of Saskatchewan, Canada
    Curr Drug Deliv 8:299-306. 2011
    ....
  3. ncbi Design and evaluation of cyclodextrin-based delivery systems to incorporate poorly soluble curcumin analogs for the treatment of melanoma
    Deborah Michel
    Drug Design and Discovery Research Group, University of Saskatchewan, Saskatoon, Canada
    Eur J Pharm Biopharm 81:548-56. 2012
    ..The goal is to develop this novel nanoparticle approach into a non-invasive therapy for in-transit melanoma metastasis that lacks adequate treatment to date...
  4. ncbi DNA delivery for vaccination and therapeutics through the skin
    Marianna Foldvari
    College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Sask, Canada
    Curr Drug Deliv 3:17-28. 2006
    ..This paper reviews the formulation approaches and delivery methods for DNA through the skin in the context of the barriers both at the tissue and cellular levels for both vaccine and gene therapy applications...
  5. ncbi Gene delivery into human skin in vitro using biphasic lipid vesicles
    Marianna Foldvari
    College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK S7N 5C9, Canada
    Curr Drug Deliv 3:89-93. 2006
    ..The successful delivery of this large (approximately 4,400 kDa) charged molecule through intact stratum corneum represents a major advance in transdermal macromolecule delivery...
  6. ncbi In vivo cutaneous interferon-gamma gene delivery using novel dicationic (gemini) surfactant-plasmid complexes
    Ildiko Badea
    College of Pharmacy and Nutrition, University of Saskatchewan, SK. S7N 5C9, Canada
    J Gene Med 7:1200-14. 2005
    ..05), and 4-6-fold higher than the Dc-chol-DNA complex, indicating a significant advance in topical DNA delivery across intact skin in vivo...
  7. ncbi Topical non-invasive gene delivery using gemini nanoparticles in interferon-gamma-deficient mice
    Ildiko Badea
    College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada
    Eur J Pharm Biopharm 65:414-22. 2007
    ....
  8. ncbi Study on protein conformation and adsorption behaviors in nanodiamond particle-protein complexes
    Hai Dong Wang
    Department of Biomedical Engineering, University of Saskatchewan, Saskatoon S7N5A9, Canada
    Nanotechnology 22:145703. 2011
    ..The results show that ND is an excellent platform for protein immobilization with high affinity and holds great potential to be used for biosensor applications...
  9. ncbi Tandem mass spectrometric analysis of novel diquaternary ammonium gemini surfactants and their bromide adducts in electrospray-positive ion mode ionization
    Joshua Buse
    College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada
    J Mass Spectrom 46:1060-70. 2011
    ..Understanding the ionization and fragmentation behaviour of gemini surfactants, including bromine adducts, will allow for future qualitative and quantitative identification of these novel drug delivery agents within biological samples...
  10. ncbi Enhanced gene expression in epithelial cells transfected with amino acid-substituted gemini nanoparticles
    Peng Yang
    Department of Chemistry, University of Saskatchewan, Saskatoon, Canada
    Eur J Pharm Biopharm 75:311-20. 2010
    ..The superior performance of these spacer-substituted gemini surfactants might be attributed to their better biocompatibility compared to the surfactants possessing unsubstituted spacers...
  11. ncbi Transdermal delivery of insulin from a novel biphasic lipid system in diabetic rats
    Martin J King
    PharmaDerm Laboratories Ltd, Saskatoon, Saskatchewan, Canada
    Diabetes Technol Ther 4:479-88. 2002
    ..These results support the feasibility of developing a transdermal insulin patch for human applications...