J Malcom O Arnold
Affiliation: University of Western Ontario
- Canadian Cardiovascular Society consensus conference recommendations on heart failure 2006: diagnosis and managementJ Malcolm O Arnold
University of Western Ontario, London, Canada
Can J Cardiol 22:23-45. 2006..The goal is to translate best evidence-based therapies into clinical practice with a measureable impact on the health of heart failure patients in Canada...
- Canadian Cardiovascular Society Consensus Conference recommendations on heart failure update 2007: Prevention, management during intercurrent illness or acute decompensation, and use of biomarkersJ Malcom O Arnold
University of Western Ontario, London, Canada
Can J Cardiol 23:21-45. 2007....
- Prevention of Heart Failure in Patients in the Heart Outcomes Prevention Evaluation (HOPE) StudyJ Malcolm O Arnold
London Health Sciences Centre, London, Canada
Circulation 107:1284-90. 2003..We assessed an angiotensin-converting enzyme (ACE) inhibitor, ramipril, to prevent the development of heart failure in high-risk patients without known low ejection fraction or heart failure...
- Improving the continuity of care following discharge of patients hospitalized with heart failure: is the discharge summary adequate?Amish N Raval
Division of Cardiology, London Health Sciences Centre, Department of Medicine, University of Western Ontario, Lawson Health Research Institute, London, Canada
Can J Cardiol 19:365-70. 2003..To determine the adequacy of the discharge summary in reporting important investigative results and future management plans in patients hospitalized and discharged with a diagnosis of heart failure...
- Pilot study to determine the impact of a multidisciplinary educational intervention in patients hospitalized with heart failureFemida H Gwadry-Sridhar
Division of Critical Care, London Health Sciences Centre, London, Ontario, Canada
Am Heart J 150:982. 2005..85, 95% CI 0.55-1.30). CONCLUSIONS: An inhospital educational intervention improved knowledge and, possibly, quality of life and may be useful as part of a comprehensive compliance enhancing strategy in patients with HF...
- The 2010 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2 - therapyDaniel G Hackam
Department of Medicine and Epidemiology, Division of Clinical Pharmacology and Clinical Neurological Sciences, University of Western Ontario, London, Ontario
Can J Cardiol 26:249-58. 2010..To update the evidence-based recommendations for the prevention and treatment of hypertension in adults for 2010...
- Instruments to measure acceptability of information and acquisition of knowledge in patients with heart failureFemida Gwadry-Sridhar
Division of Cardiology, London Health Sciences Centre, London, Canada
Eur J Heart Fail 5:783-91. 2003..Providing patients with knowledge through education is one mechanism to help them improve compliance with complicated treatment regimens...
- Effects of enalaprilat on venoconstriction to norepinephrine: role of prostaglandinsT Nancy Dzeka
Department of Physiology, The University of Western Ontario and Lawson Health Research Institute, Ontario, London, Canada
Cardiovasc Res 59:250-6. 2003..This may have clinical relevance in patients receiving aspirin and ACE inhibitors in the setting of increased sympathetic activity...
- Predictors of late development of heart failure in stable survivors of myocardial infarction: the CARE studyEldrin F Lewis
Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
J Am Coll Cardiol 42:1446-53. 2003..Patients who experience late-onset HF have a 10-fold increased risk of death compared with other MI survivors. Baseline characteristics can risk stratify patients at high risk of subsequent HF...
- Comparison of regional versus global assessment of left ventricular function in patients with left ventricular dysfunction, heart failure, or both after myocardial infarction: the valsartan in acute myocardial infarction echocardiographic studyJens Jakob Thune
Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
J Am Soc Echocardiogr 19:1462-5. 2006..Regional assessment might be a more sensitive predictor of outcome than global assessment in patients with acute MI...
- Long-term effects of ramipril on cardiovascular events and on diabetes: results of the HOPE study extensionJackie Bosch
Division of Cardiology, Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
Circulation 112:1339-46. 2005..6 years of follow-up and (2) observed in subgroups based on risk and ancillary treatments...
- Caring for patients with heart failureAnna Svendsen
Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia
Can Nurse 102:14-5, 17. 2006
- On the rise: The current and projected future burden of congestive heart failure hospitalization in CanadaHelen Johansen
Health Statistics Division, Statistics Canada, Ottawa, Ontario, Canada
Can J Cardiol 19:430-5. 2003..This has been reported internationally but no systematic epidemiological assessment of CHF has been conducted for Canada nationally...
- Long-term trandolapril treatment is associated with reduced aortic stiffness: the prevention of events with angiotensin-converting enzyme inhibition hemodynamic substudyGary F Mitchell
Cardiovascular Engineering, Inc, Waltham, MA 02453, USA
Hypertension 49:1271-7. 2007....
- Augmentation index and central aortic stiffness in middle-aged to elderly individualsMitul Vyas
Cardiovascular Engineering, Inc, Waltham, Massachusetts 02453, USA
Am J Hypertens 20:642-7. 2007..We evaluated this hypothesis by investigating relations between AI and other direct measures of aortic stiffness...
- Effect of angiotensin receptor blockade and antihypertensive drugs on diastolic function in patients with hypertension and diastolic dysfunction: a randomised trialScott D Solomon
Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
Lancet 369:2079-87. 2007....
- The relationship between renal function and cardiac structure, function, and prognosis after myocardial infarction: the VALIANT Echo StudyAnil Verma
Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
J Am Coll Cardiol 50:1238-45. 2007..The purpose of this study was to determine whether alterations in cardiac structure or function contribute to the increased risk associated with renal impairment after myocardial infarction (MI)...
- Homocysteine lowering with folic acid and B vitamins in people with chronic kidney disease--results of the renal Hope-2 studyJohannes F E Mann
Department of Medicine, Munich General Hospitals and KfH Kidney Centre, Munich, Germany
Nephrol Dial Transplant 23:645-53. 2008..Elevated plasma homocysteine levels are reported to be associated with higher rates of vascular diseases. Plasma homocysteine increases in chronic kidney disease (CKD) and could contribute to the increased cardiovascular risk in CKD...
- Influence of albuminuria on cardiovascular risk in patients with stable coronary artery diseaseScott D Solomon
Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
Circulation 116:2687-93. 2007..We assessed the association between albuminuria and the risks for death and cardiovascular events among patients with stable coronary disease...
- Aortic diameter, wall stiffness, and wave reflection in systolic hypertensionGary F Mitchell
Cardiovascular Engineering Inc, University Office Park, Bldg 2, Suite 100, 51 Sawyer Road, Waltham, MA 02453, USA
Hypertension 51:105-11. 2008..Among individuals with systolic hypertension, increased PP is primarily attributable to increased wall stiffness and reduced aortic diameter rather than premature wave reflection...
- Rhythm control versus rate control for atrial fibrillation and heart failureDenis Roy
Montreal Heart Institute and the Université de Montréal, Montreal, QC H1T 1C8, Canada
N Engl J Med 358:2667-77. 2008..However, the benefits and risks of this approach have not been adequately studied...
- Mitral regurgitation in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both: prognostic significance and relation to ventricular size and functionMaria Amigoni
Brigham and Women s Hospital, Boston, Massachusetts, USA
Eur Heart J 28:326-33. 2007....
- Value of the electrocardiogram in predicting left ventricular enlargement and dysfunction after myocardial infarctionCostantina Manes
Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
Am J Med 114:99-105. 2003..Predischarge ECG may be a useful tool for early identification of patients at risk of ventricular enlargement and persistent dysfunction following myocardial infarction...
- Heart failure clinics and outpatient management: review of the evidence and call for quality assuranceFinn Gustafsson
Department of Cardiology, Rigshospitalet, Copenhagen, Denmark
Eur Heart J 25:1596-604. 2004..One possible, practical method to apply such continuous quality assurance may be by means of electronic medical record databases...
- Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trialEva Lonn
Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario
JAMA 293:1338-47. 2005..CONCLUSION: In patients with vascular disease or diabetes mellitus, long-term vitamin E supplementation does not prevent cancer or major cardiovascular events and may increase the risk for heart failure...
- Changes in ventricular size and function in patients treated with valsartan, captopril, or both after myocardial infarctionScott D Solomon
Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
Circulation 111:3411-9. 2005....
- ACC/AHA key data elements and definitions for measuring the clinical management and outcomes of patients with chronic heart failure: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing CMartha J Radford
Circulation 112:1888-916. 2005
- Pulsatile hemodynamic effects of candesartan in patients with chronic heart failure: the CHARM ProgramGary F Mitchell
Cardiovascular Engineering, Inc, 327 Fiske Street, Holliston, MA 01746, USA
Eur J Heart Fail 8:191-7. 2006..Abnormal large artery function and increased pulsatile load are exacerbated by excess angiotensin-II acting through the AT1 receptor and contribute to the pathogenesis and progression of chronic heart failure (CHF)...
- Changes in aortic stiffness and augmentation index after acute converting enzyme or vasopeptidase inhibitionGary F Mitchell
Cardiovascular Engineering, Inc, Waltham, MA 02453, USA
Hypertension 46:1111-7. 2005..Our findings indicate that AI is a complex surrogate marker that is inversely related to changes in proximal aortic stiffness in systolic hypertension...
- Treating the right patient at the right time: access to heart failure careH Ross
Department of Medicine, University Health Network, University of Toronto, Toronto, Canada
Can J Cardiol 22:749-54. 2006....
- Rationale and design: the VALsartan In Diastolic Dysfunction (VALIDD) Trial: evolving the management of diastolic dysfunction in hypertensionRajesh Janardhanan
Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
Am Heart J 152:246-52. 2006..The trial may provide clinically useful data on whether such therapy can directly improve diastolic function in patients with hypertension...
- Prostaglandin modulation of venoconstriction to physiological stress in normals and heart failure patientsT Nancy Dzeka
Department of Physiology, The University of Western Ontario, London, Ontario, Canada N6A 4G5
Am J Physiol Heart Circ Physiol 284:H790-7. 2003..036). Inhibition of prostaglandins by indomethacin significantly enhances hand vein constriction to physiological stimuli in both normals and CHF patients, although a differential effect exists for LBNP...