Research Topics
| A H AnisSummaryAffiliation: University of British Columbia Country: Canada Publications
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Detail Information
Publications
Using pharmacoeconomic analysis to make drug insurance coverage decisionsA H Anis
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, Canada
Pharmacoeconomics 13:119-26. 1998....- Economic evaluation of propofol for sedation of patients admitted to intensive care unitsAslam H Anis
Department of Health Care and Epidemiology, University of British Columbia, Canada
Anesthesiology 96:196-201. 2002..The goal of the current study was to evaluate the economic impact of propofol as compared with midazolam for sedating patients in the intensive care unit (ICU)... - A dog's breakfast: prescription drug coverage varies widely across CanadaA H Anis
Department of Health Care and Epidemiology, University of British Columbia, Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, Vancouver, Canada
Med Care 39:315-26. 2001..Each province in Canada independently assesses drugs for their reimbursement eligibility. Publicly funded access to specific drugs is therefore dependent on province of residence... 
Double trouble: impact of inappropriate use of asthma medication on the use of health care resourcesA H Anis
Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, Vancouver, BC
CMAJ 164:625-31. 2001....- Using economic evaluations to make formulary coverage decisions. So much for guidelinesA H Anis
Center for Health Evaluation and Outcome Sciences, St Paul s Hospital, Vancouver, British Columbia, Canada
Pharmacoeconomics 18:55-62. 2000..These submissions are reviewed by the Pharmacoeconomic Initiative (PI) of BC... - The costs of cardiorespiratory disease episodes in a study of emergency department useA H Anis
Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, Vancouver, BC
Can J Public Health 91:103-6. 2000..The average per person direct cost of illness of cardiorespiratory disease episodes was estimated based on a prospective study of emergency department visits... - Pharmaceutical policies in Canada: another example of federal-provincial discordA H Anis
Department of Health Care and Epidemiology, University of British Columbia, Vancouver
CMAJ 162:523-6. 2000..In contrast, provincial governments have no jurisdiction over market competitiveness or pricing, yet end up paying for most of the drug expenditures incurred... - The social determinants of emergency department and hospital use by injection drug users in CanadaA Palepu
Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, Vancouver, BC, Canada
J Urban Health 76:409-18. 1999..The aim of this study was to describe the relationship between sociodemographic characteristics and human immunodeficiency (HIV) status of a cohort of injection drug users (IDUs) on their self-reported health service utilization... - Average annual drug cost and its determinants in a population based cohort of HIV-positive adult men and womenA H Anis
Canadian HIV Trials Network, Vancouver, British Columbia, Canada
Pharmacoeconomics 13:327-36. 1998..Important cost drivers were participant's age, socioeconomic status (by provincial drug insurance coverage level) and rate of disease progression as measured by CD4+ cell counts, hospitalisation events and duration of illness... - Modelling the potential economic impact of viral load-driven triple drug combination antiretroviral therapyA H Anis
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
Pharmacoeconomics 13:697-705. 1998.... 
Economic evaluation of systemic therapies for moderate to severe psoriasisS Sizto
Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, Vancouver, BC, Canada
Br J Dermatol 160:1264-72. 2009..New biologics have dramatically changed therapeutic options for psoriasis, albeit at additional cost...- The effectiveness and toxicity of cyclosporin A in rheumatoid arthritis: longitudinal analysis of a population-based registryC A Marra
Department of Health Care and Epidemiology, Faculty of Medicine, University of British Columbia, and Centre for Health Evaluation and Outcomes Sciences, St. Paul's Hospital, Vancouver, Canada
Arthritis Rheum 45:240-5. 2001..7), and DBP (3.8 mm Hg, 95% CI 3.0-6.4). CONCLUSIONS: Combination CSA/MTX prolongs therapy and reduces JC. Long-term CSA treatment was fairly well tolerated. Previous DMARD use appears to be a determinant for the development of toxicity... - The cost of fall related presentations to the ED: a prospective, in-person, patient-tracking analysis of health resource utilizationJ C Woolcott
Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada
Osteoporos Int 23:1513-9. 2012..Using data collected on 102 falls, we found the average cost per fall causing an Emergency Department presentation of $11,408. When hospitalization was required, the average cost per fall was $29,363... - Hospital utilization and costs in a cohort of injection drug usersA Palepu
Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, Department of Medicine, University of British Columbia, Vancouver
CMAJ 165:415-20. 2001.... - The effect of homelessness on hospitalisation among patients with HIV/AIDSB Nosyk
Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, Vancouver, Canada
AIDS Care 19:546-53. 2007.... - Not all "quality-adjusted life years" are equalC A Marra
Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada
J Clin Epidemiol 60:616-24. 2007..There is evidence that utility elicitation methods used in the calculation of quality-adjusted life years (QALYs) yield different results. It is not clear how these differences impact economic evaluations... - Validity of the work productivity and activity impairment questionnaire--general health version in patients with rheumatoid arthritisWei Zhang
Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, 620 1081 Burrard Street, Vancouver, BC V6Z 1Y6, Canada
Arthritis Res Ther 12:R177. 2010..The present study's purpose is to evaluate the construct validity of the WPAI-general health version among RA patients and its ability to differentiate between RA patients with varying health status... - Proportional hazards frailty models for recurrent methadone maintenance treatmentBohdan Nosyk
Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute, Vancouver, British Columbia, Canada
Am J Epidemiol 170:783-92. 2009..Many reenter treatment. The primary finding of this study was that patients experiencing multiple treatment episodes tended to stay in treatment for progressively longer periods in later episodes... - The concurrent validity and responsiveness of the health utilities index (HUI 3) among patients with advanced HIV/AIDSBohdan Nosyk
Canadian HIV Trials Network, St Paul s Hospital, 620 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada
Qual Life Res 18:815-24. 2009..To assess the concurrent validity and responsiveness of the Health Utility Index 3 (HUI3) in patients with advanced HIV/AIDS, and to determine the responsiveness of this measure, the MOS-HIV and EQ-5D to HIV-related clinical events... - Suture closure of femoral arterial puncture sites after coronary angioplasty followed by same-day dischargeR G Carere
Division of Cardiology, St Paul s Hospital, University of British Columbia, Vancouver
Am Heart J 139:52-8. 2000..The purpose of this study was to determine whether immediate suture closure of 8F femoral arterial puncture sites can facilitate same-day discharge after coronary angioplasty... - Obesity and overweight in Canada: an updated cost-of-illness studyA H Anis
Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, Vancouver, BC, Canada V6Z 1Y6
Obes Rev 11:31-40. 2010..Policies to reduce being overweight and obese could potentially save the Canadian healthcare system millions of dollars... - Price regulation of pharmaceuticals in CanadaA H Anis
Health Research Centre, St Paul s Hospital, Vancouver, B C, Canada
J Health Econ 17:21-38. 1998..Canadian data supported the model's predictions. Policy makers should anticipate these responses that affects the entire vector of drug prices and not just those subject to specific regulations... - The impact of low family income on self-reported health outcomes in patients with rheumatoid arthritis within a publicly funded health-care environmentC A Marra
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, Canada
Rheumatology (Oxford) 43:1390-7. 2004..The finding that preference-based measures vary with income independently of RA severity could bias economic evaluation... - Development of a population-based microsimulation model of osteoarthritis in CanadaJ A Kopec
School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada
Osteoarthritis Cartilage 18:303-11. 2010..In this article we describe the overall structure of the model, sources of data, derivation of key input parameters for the epidemiological component of the model, and preliminary validation studies... - Predictors of early hospital readmission in HIV-infected patients with pneumoniaAnita Palepu
Received from the Department of Internal Medicine, the Centre for Health Evaluation and Outcome Sciences, Vancouver, British Columbia, Canada
J Gen Intern Med 18:242-7. 2003..Interventions involving social work may address some of the underlying reasons why these patients leave hospital AMA and should be further studied... - Intensive care unit survivors have fewer hospital readmissions and readmission days than other hospitalized patients in British ColumbiaSean P Keenan
Centre for Health Evaluation and Outcome Sciences, St. Paul's Hospital and University of British Columbia, Vancouver, B.C, Canada
Crit Care Med 32:391-8. 2004..CONCLUSIONS: Survivors of a hospital stay that includes admission to an ICU have fewer hospital readmissions and readmission days after their discharge than do survivors of a hospital stay without intensive care... - HIV-positive injection drug users who leave the hospital against medical advice: the mitigating role of methadone and social supportAlex C H Chan
Center for Health Evaluation and Outcome Sciences, Division of General Internal Medicine, University of British Columbia, St. Paul's Hospital, 1081 Burrard Street, Vancouver, British Columbia, Canada V6Z 1Y6
J Acquir Immune Defic Syndr 35:56-9. 2004..Addiction treatment and interventions that enhance social supports in marginalized populations at risk for hospital discharge AMA should be further explored... - The effect of motivational status on treatment outcome in the North American Opiate Medication Initiative (NAOMI) studyBohdan Nosyk
Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, Vancouver, British Columbia, Canada
Drug Alcohol Depend 111:161-5. 2010.... - Quality of life of patients with advanced HIV/AIDS: measuring the impact of both AIDS-defining events and non-AIDS serious adverse eventsAslam H Anis
Canadian HIV Trials Network, Vancouver, British Columbia, Canada
J Acquir Immune Defic Syndr 51:631-9. 2009..To investigate the relative magnitude and duration of impact of AIDS-defining events (ADEs) and non-AIDS serious adverse events (SAEs) on health-related quality of life (HRQoL) among patients with advanced HIV/AIDS... - Medical withdrawal management in Vancouver: service description and evaluationXin Li
Department of Healthcare and Epidemiology, University of British Columbia, Canada
Addict Behav 32:1043-53. 2007..In addition, the patterns of utilization of VD were changed over the welfare check issuance period. Our analysis indicates that operational accessibility and efficiency at VD could be improved by specifically addressing these factors... - Introduction of a practice guideline for penicillin skin testing improves the appropriateness of antibiotic therapyD M Forrest
Division of Infectious Diseases, Department of Medicine, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada
Clin Infect Dis 32:1685-90. 2001..We conclude that introduction of a guideline for penicillin skin testing increases the percentage of eligible patients who have a skin test, and it does so without increasing costs... - A comparison of generic, indirect utility measures (the HUI2, HUI3, SF-6D, and the EQ-5D) and disease-specific instruments (the RAQoL and the HAQ) in rheumatoid arthritisCarlo A Marra
Faculty of Pharmaceutical Sciences, University of British Columbia, Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, 717 828 West 10th Ave, Vancouver, BC, Canada V6Z 1Y6
Soc Sci Med 60:1571-82. 2005..We conclude that the all of the preference-based utility measures that were evaluated appear to adequately discriminate across levels of RA severity... - Assessment of health-related quality of life in arthritis: conceptualization and development of five item banks using item response theoryJacek A Kopec
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, BC, Canada
Health Qual Life Outcomes 4:33. 2006..Adaptive assessment requires an item bank for each domain of HRQL. The purpose of this study was to develop item banks for five domains of HRQL relevant to arthritis... - Factors associated with seeking readmission among clients admitted to medical withdrawal managementXin Li
Department of Healthcare and Epidemiology, University of British Columbia, Vancouver, BC, Canada
Subst Abus 29:65-72. 2008..Clients with no fixed address were less likely to seek readmission between months 2 and 12.</p>.. - Descriptive epidemiology of osteoarthritis in British Columbia, CanadaJacek A Kopec
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, BC, Canada
J Rheumatol 34:386-93. 2007.... - A comparison of four indirect methods of assessing utility values in rheumatoid arthritisCarlo A Marra
Department of Health Care and Epidemiology, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada
Med Care 42:1125-31. 2004..Agreement among the instruments was moderate but poorer at lower utilities. It is unlikely that these utility values, if used as the weightings for quality-adjusted life years, would result in comparable estimates... - The validity of generic and condition-specific preference-based instruments: the ability to discriminate asthma control statusHelen M McTaggart-Cowan
Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, 7th Floor, 828 West 10th Avenue, Vancouver, BC, Canada, V5Z 1L8
Qual Life Res 17:453-62. 2008..The objective of this study was to evaluate the validity of generic and condition-specific preference-based instruments, in terms of their ability to distinguish asthma control... - Length of ICU stay for chronic obstructive pulmonary disease varies among large community hospitalsSean P Keenan
Centre for Health Evaluation and Outcome Sciences, St. Paul's Hospital 620B-1081 Burrard and University of British Columbia, V6Z 1Y6, Vancouver, British Columbia, Canada
Intensive Care Med 29:590-5. 2003..These small area variations may point to opportunities to improve efficiency of care. Further prospective, detailed data collection is required to validate these observations and to identify factors responsible for any differences found... - Trends in methadone maintenance treatment participation, retention, and compliance to dosing guidelines in British Columbia, Canada: 1996-2006Bohdan Nosyk
Centre for Health Evaluation and Outcome Sciences, Vancouver, British Columbia
J Subst Abuse Treat 39:22-31. 2010..9% in 2001 to 40.5% in 2005. Our evaluation has both highlighted the successes of the British Columbia Methadone program and identified aspects that may be improved to ensure safety and maximize the benefits of MMT... - Impact of supply-side policies for control of illicit drugs in the face of the AIDS and overdose epidemics: investigation of a massive heroin seizureEvan Wood
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, BC
CMAJ 168:165-9. 2003..Closer scrutiny of enforcement efforts is warranted to ensure that resources are delivered to the most efficient and cost-effective public health programs... - The quality of eight health status measures were compared for chronic opioid dependenceBohdan Nosyk
Centre for Health Evaluation and Outcome Sciences, British Columbia, Canada
J Clin Epidemiol 63:1132-44. 2010..To provide a comparative analysis of the psychometric properties of eight measures of health status among chronic opioid-dependent patients... - Are indirect utility measures reliable and responsive in rheumatoid arthritis patients?Carlo A Marra
Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
Qual Life Res 14:1333-44. 2005..Therefore, we examined the reliability and responsiveness of these measures and the Rheumatoid Arthritis Quality of Life (RAQoL) and the Health Assessment Questionnaire (HAQ) in a sample of RA patients... - When patients have to pay a share of drug costs: effects on frequency of physician visits, hospital admissions and filling of prescriptionsAslam H Anis
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, BC
CMAJ 173:1335-40. 2005..We investigated the effect of prescription drug cost-sharing on overall health care utilization among elderly patients with rheumatoid arthritis... - Intensive care unit admission has minimal impact on long-term mortalitySean P Keenan
Centre for Health Evaluation and Outcome Sciences, St. Paul's Hospital and University of British Columbia, Vancouver, Canada
Crit Care Med 30:501-7. 2002..17-1.27) and was completely overshadowed by the effect of age, gender, and diagnosis. CONCLUSIONS: After controlling for the effect of hospital admission, admission to ICU has minimal independent effect on mortality after discharge... - Safety and efficiency of emergency department assessment of chest discomfortJim Christenson
Department of Surgery, University of British Columbia, and Department of Emergency Medicine, Providence Health Care, St Paul s Hospital, Vancouver, BC
CMAJ 170:1803-7. 2004.... - Trends in physician-diagnosed osteoarthritis incidence in an administrative database in British Columbia, Canada, 1996-1997 through 2003-2004Jacek A Kopec
University of British Columbia, Vancouver, British Columbia, Canada
Arthritis Rheum 59:929-34. 2008..The purpose of this study was to describe changes in physician-diagnosed OA incidence rates between 1996-1997 and 2003-2004 in British Columbia (BC), Canada... - Short-term influence of adalimumab on work productivity outcomes in patients with rheumatoid arthritisWei Zhang
Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, Vancouver, British Columbia, Canada
J Rheumatol 35:1729-36. 2008..To evaluate the shortterm effect of adalimumab on work productivity in patients with moderate to severe active rheumatoid arthritis (RA)... - Use of nonbiologic disease-modifying antirheumatic drugs and risk of infection in patients with rheumatoid arthritisDiane Lacaille
University of British Columbia and Arthritis Research Centre of Canada, 895 West 10th Avenue, Vancouver, BC, Canada
Arthritis Rheum 59:1074-81. 2008..This study was undertaken to determine the effect of nonbiologic disease-modifying antirheumatic drugs (DMARDs) on infection risk in RA... - The indirect costs of arthritis resulting from unemployment, reduced performance, and occupational changes while at workXin Li
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, British Columbia, Canada
Med Care 44:304-10. 2006..10), and higher depression (OR = 1.04). CONCLUSIONS: Indirect arthritis-related costs are substantial. Our results show that not only the disease itself, but also psychosocial and work-related factors affect the magnitude of the costs... - Reconcilable differences: a cross-sectional study of the relationship between socioeconomic status and the magnitude of short-acting beta-agonist use in asthmaLarry D Lynd
Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
Chest 126:1161-8. 2004..Results were consistent for neighborhood unemployment rate. CONCLUSIONS: The social gradient in asthma-related outcomes may be at least partially attributable to poorer asthma control in lower-SES asthmatics... - Lowering generic drug prices: less regulation equals more competitionAslam H Anis
Department of Health Care and Epidemiology, University of British Columbia, Centre for Health Evaluation and Outcomes Research, St Paul s Hospital, Vancouver, Canada
Med Care 41:135-41. 2003..Accordingly, the first generic entrant's price could not exceed 70% of the incumbent's branded price. Subsequent entrants' prices could not exceed 90% of the first entrant's price... - Gaps in care for rheumatoid arthritis: a population studyDiane Lacaille
University of British Columbia, and Arthritis Research Centre of Canada, Vancouver, British Columbia, Canada
Arthritis Rheum 53:241-8. 2005..This research assesses whether care for RA, at a population level, is consistent with current treatment guidelines... - A cost-utility analysis of losartan versus atenolol in the treatment of hypertension with left ventricular hypertrophyAslam H Anis
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, British Columbia, Canada
Pharmacoeconomics 24:387-400. 2006..Incorporating the results found in the LIFE study into an economic model, an incremental cost-effectiveness analysis was performed comparing losartan with atenolol in the treatment of 67-year old patients with hypertension and LVH... - Do visual analogue scale (VAS) derived standard gamble (SG) utilities agree with Health Utilities Index utilities? A comparison of patient and community preferences for health status in rheumatoid arthritis patientsAmir Adel Rashidi
Centre for Clinical Epidemiology and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, Canada
Health Qual Life Outcomes 4:25. 2006..The objective of this study is to assess the agreement between community preferences derived from the Health Utilities Index Mark 2 (HUI2) and Mark 3 (HUI3) systems, and patient preferences... - Highly active antiretroviral therapy and hospital readmission: comparison of a matched cohortBohdan Nosyk
Canadian HIV Trials Network, St, Paul s Hospital, Vancouver, BC, Canada
BMC Infect Dis 6:146. 2006..Paul's Hospital (SPH) in Vancouver, BC, Canada... - The impact of cost sharing of prescription drug expenditures on health care utilization by the elderly: own- and cross-price elasticitiesXin Li
Department of Health Care and Epidemiology, University of British Columbia, and Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, Vancouver, Canada
Health Policy 82:340-7. 2007.... - Patterns of inhaled asthma medication use: a 3-year longitudinal analysis of prescription claims data from British Columbia, CanadaLarry D Lynd
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, BC, Canada V6Z 1Y6
Chest 122:1973-81. 2002..An unexpected trend toward decreasing ICS utilization was identified. Receiving social assistance was a risk factor for increasing SA beta-agonist use, independent of baseline utilization... - Cost-effectiveness of hip protectors in the prevention of osteoporosis related hip fractures in elderly nursing home residentsSonia Singh
Department of Healthcare and Epidemiology, University of British Columbia, Vancouver, British Columbia, Canada
J Rheumatol 31:1607-13. 2004..CONCLUSION: Cost-effectiveness analysis suggests that hip protectors could save money while preventing hip fractures and improving quality of life in nursing home residents... - An overview of economic evaluations for drugs used in rheumatoid arthritis : focus on tumour necrosis factor-alpha antagonistsNick J Bansback
Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, Sheffield, UK
Drugs 65:473-96. 2005.... - Leaving hospital against medical advice among HIV-positive patientsAslam H Anis
British Columbia Centre for Excellence in HIV AIDS, Canadian HIV Trials Network, Vancouver
CMAJ 167:633-7. 2002..Because of the high prevalence of injection drug use among HIV-positive patients admitted to hospital in Vancouver, we explored the factors associated with leaving hospital against medical advice in this population... - National pharmacare: a dog's taleAslam H Anis
CMAJ 171:565-6. 2004