Peter Andolfatto

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. pmc Multilocus patterns of nucleotide variability and the demographic and selection history of Drosophila melanogaster populations
    Penelope R Haddrill
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3JT, United Kingdom
    Genome Res 15:790-9. 2005
  2. pmc Linkage disequilibrium patterns across a recombination gradient in African Drosophila melanogaster
    Peter Andolfatto
    Department of Zoology, University of Toronto, Toronto, Ontario M5S 3G5, Canada
    Genetics 165:1289-305. 2003
  3. pmc Testing models of selection and demography in Drosophila simulans
    Jeffrey D Wall
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138, USA
    Genetics 162:203-16. 2002
  4. pmc Positive and negative selection on noncoding DNA in Drosophila simulans
    Penelope R Haddrill
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom
    Mol Biol Evol 25:1825-34. 2008
  5. pmc Hitchhiking effects of recurrent beneficial amino acid substitutions in the Drosophila melanogaster genome
    Peter Andolfatto
    Division of Biological Sciences, University of California San Diego, La Jolla, California 92093, USA
    Genome Res 17:1755-62. 2007
  6. pmc Selection, recombination and demographic history in Drosophila miranda
    Doris Bachtrog
    Division of Biological Sciences, University of California, San Diego, California 92093, USA
    Genetics 174:2045-59. 2006
  7. pmc X chromosomes and autosomes evolve at similar rates in Drosophila: no evidence for faster-X protein evolution
    Kevin Thornton
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
    Genome Res 16:498-504. 2006
  8. ncbi request reprint Adaptive evolution of non-coding DNA in Drosophila
    Peter Andolfatto
    Section of Ecology, Behavior and Evolution, Division of Biological Sciences, University of California San Diego, La Jolla, California 92093, USA
    Nature 437:1149-52. 2005
  9. pmc Patterns of intron sequence evolution in Drosophila are dependent upon length and GC content
    Penelope R Haddrill
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, UK
    Genome Biol 6:R67. 2005
  10. pmc Patterns of evolutionary constraints in intronic and intergenic DNA of Drosophila
    Daniel L Halligan
    University of Edinburgh, School of Biological Sciences, Edinburgh EH9 3JT, UK
    Genome Res 14:273-9. 2004

Detail Information

Publications12

  1. pmc Multilocus patterns of nucleotide variability and the demographic and selection history of Drosophila melanogaster populations
    Penelope R Haddrill
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3JT, United Kingdom
    Genome Res 15:790-9. 2005
    ..Demographic departures from equilibrium expectations in both ancestral and derived populations thus represent a serious challenge to detecting positive selection in genome-wide scans using current methodologies...
  2. pmc Linkage disequilibrium patterns across a recombination gradient in African Drosophila melanogaster
    Peter Andolfatto
    Department of Zoology, University of Toronto, Toronto, Ontario M5S 3G5, Canada
    Genetics 165:1289-305. 2003
    ..e., toward an excess of LD) in this Zimbabwean population. Our results also have implications for the dynamics of weakly selected mutations in regions of reduced crossing over...
  3. pmc Testing models of selection and demography in Drosophila simulans
    Jeffrey D Wall
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138, USA
    Genetics 162:203-16. 2002
    ..autosome variability levels, they suggest that demography alone may account for patterns of linkage disequilibrium and the frequency spectrum of segregating mutations in this population of D. simulans...
  4. pmc Positive and negative selection on noncoding DNA in Drosophila simulans
    Penelope R Haddrill
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom
    Mol Biol Evol 25:1825-34. 2008
    ..simulans lineage difficult to reconcile with demographic explanations...
  5. pmc Hitchhiking effects of recurrent beneficial amino acid substitutions in the Drosophila melanogaster genome
    Peter Andolfatto
    Division of Biological Sciences, University of California San Diego, La Jolla, California 92093, USA
    Genome Res 17:1755-62. 2007
    ....
  6. pmc Selection, recombination and demographic history in Drosophila miranda
    Doris Bachtrog
    Division of Biological Sciences, University of California, San Diego, California 92093, USA
    Genetics 174:2045-59. 2006
    ..These departures from neutral equilibrium expectations are discussed in the context of nonequilibrium models of demography and selection...
  7. pmc X chromosomes and autosomes evolve at similar rates in Drosophila: no evidence for faster-X protein evolution
    Kevin Thornton
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
    Genome Res 16:498-504. 2006
    ..The lack of a detectable faster-X effect in these species suggests either that beneficial amino acids are not partially recessive on average, or that adaptive evolution does not often use newly arising amino acid mutations...
  8. ncbi request reprint Adaptive evolution of non-coding DNA in Drosophila
    Peter Andolfatto
    Section of Ecology, Behavior and Evolution, Division of Biological Sciences, University of California San Diego, La Jolla, California 92093, USA
    Nature 437:1149-52. 2005
    ..These results imply that, although positive selection is clearly an important facet of protein evolution, adaptive changes to non-coding DNA might have been considerably more common in the evolution of D. melanogaster...
  9. pmc Patterns of intron sequence evolution in Drosophila are dependent upon length and GC content
    Penelope R Haddrill
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, UK
    Genome Biol 6:R67. 2005
    ..No consistent patterns have emerged from studies that have investigated general levels of evolutionary constraint in introns...
  10. pmc Patterns of evolutionary constraints in intronic and intergenic DNA of Drosophila
    Daniel L Halligan
    University of Edinburgh, School of Biological Sciences, Edinburgh EH9 3JT, UK
    Genome Res 14:273-9. 2004
    ....
  11. ncbi request reprint No association between mitochondrial DNA haplotypes and a female-limited mimicry phenotype in Papilio glaucus
    Peter Andolfatto
    Institute of Cell, Animal and Population Biology, University of Edinburgh, Edinburgh Scotland, EH9 3JT United Kingdom
    Evolution 57:305-16. 2003
    ..This finding suggests that genetic exchanges between maternal and paternal mitochondrial DNAs may have contributed to the lack of association we observe between phenotype and genotype...
  12. pmc An approximate bayesian estimator suggests strong, recurrent selective sweeps in Drosophila
    Jeffrey D Jensen
    Section of Ecology, Behavior and Evolution, University of California San Diego, La Jolla, California, United States of America
    PLoS Genet 4:e1000198. 2008
    ..It will thus be of great interest to apply this method to emerging whole-genome polymorphism data sets in many taxa...