- Multilocus patterns of nucleotide variability and the demographic and selection history of Drosophila melanogaster populations
Penelope R Haddrill
Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3JT, United Kingdom
Genome Res 15:790-9. 2005
..Demographic departures from equilibrium expectations in both ancestral and derived populations thus represent a serious challenge to detecting positive selection in genome-wide scans using current methodologies...
- Linkage disequilibrium patterns across a recombination gradient in African Drosophila melanogaster
Department of Zoology, University of Toronto, Toronto, Ontario M5S 3G5, Canada
Genetics 165:1289-305. 2003
..e., toward an excess of LD) in this Zimbabwean population. Our results also have implications for the dynamics of weakly selected mutations in regions of reduced crossing over...
- Testing models of selection and demography in Drosophila simulans
Jeffrey D Wall
Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138, USA
Genetics 162:203-16. 2002
..autosome variability levels, they suggest that demography alone may account for patterns of linkage disequilibrium and the frequency spectrum of segregating mutations in this population of D. simulans...
- Positive and negative selection on noncoding DNA in Drosophila simulans
Penelope R Haddrill
Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom
Mol Biol Evol 25:1825-34. 2008
..simulans lineage difficult to reconcile with demographic explanations...
- Hitchhiking effects of recurrent beneficial amino acid substitutions in the Drosophila melanogaster genome
Division of Biological Sciences, University of California San Diego, La Jolla, California 92093, USA
Genome Res 17:1755-62. 2007
- Selection, recombination and demographic history in Drosophila miranda
Division of Biological Sciences, University of California, San Diego, California 92093, USA
Genetics 174:2045-59. 2006
..These departures from neutral equilibrium expectations are discussed in the context of nonequilibrium models of demography and selection...
- X chromosomes and autosomes evolve at similar rates in Drosophila: no evidence for faster-X protein evolution
Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
Genome Res 16:498-504. 2006
..The lack of a detectable faster-X effect in these species suggests either that beneficial amino acids are not partially recessive on average, or that adaptive evolution does not often use newly arising amino acid mutations...
- Adaptive evolution of non-coding DNA in Drosophila
Section of Ecology, Behavior and Evolution, Division of Biological Sciences, University of California San Diego, La Jolla, California 92093, USA
Nature 437:1149-52. 2005
..These results imply that, although positive selection is clearly an important facet of protein evolution, adaptive changes to non-coding DNA might have been considerably more common in the evolution of D. melanogaster...
- Patterns of intron sequence evolution in Drosophila are dependent upon length and GC content
Penelope R Haddrill
Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, UK
Genome Biol 6:R67. 2005
..No consistent patterns have emerged from studies that have investigated general levels of evolutionary constraint in introns...
- Patterns of evolutionary constraints in intronic and intergenic DNA of Drosophila
Daniel L Halligan
University of Edinburgh, School of Biological Sciences, Edinburgh EH9 3JT, UK
Genome Res 14:273-9. 2004
- No association between mitochondrial DNA haplotypes and a female-limited mimicry phenotype in Papilio glaucus
Institute of Cell, Animal and Population Biology, University of Edinburgh, Edinburgh Scotland, EH9 3JT United Kingdom
Evolution 57:305-16. 2003
..This finding suggests that genetic exchanges between maternal and paternal mitochondrial DNAs may have contributed to the lack of association we observe between phenotype and genotype...
- An approximate bayesian estimator suggests strong, recurrent selective sweeps in Drosophila
Jeffrey D Jensen
Section of Ecology, Behavior and Evolution, University of California San Diego, La Jolla, California, United States of America
PLoS Genet 4:e1000198. 2008
..It will thus be of great interest to apply this method to emerging whole-genome polymorphism data sets in many taxa...