Rotimi E Aluko

Summary

Affiliation: University of Manitoba
Country: Canada

Publications

  1. doi Emulsifying and foaming properties of commercial yellow pea (Pisum sativum L.) seed flours
    Rotimi E Aluko
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada R3T 2N2
    J Agric Food Chem 57:9793-800. 2009
  2. ncbi Technology for the production and utilization of food protein-derived anti-hypertensive peptides: a review
    Rotimi E Aluko
    Department of Human Nutritional Sciences and the Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg, Manitoba, R3T 2N2, Canada
    Recent Pat Biotechnol 1:260-7. 2007
  3. ncbi Determination of nutritional and bioactive properties of peptides in enzymatic pea, chickpea, and mung bean protein hydrolysates
    Rotimi E Aluko
    University of Manitoba, Department of Human Nutritional Sciences and the Richardson Centre for Functional Foods and Nutraceuticals, Winnipeg, MB, Canada
    J AOAC Int 91:947-56. 2008
  4. ncbi Multifunctional cationic peptide fractions from flaxseed protein hydrolysates
    Chibuike C Udenigwe
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada
    Plant Foods Hum Nutr 67:1-9. 2012
  5. doi Reverse-phase HPLC separation of hemp seed (Cannabis sativa L.) protein hydrolysate produced peptide fractions with enhanced antioxidant capacity
    Abraham T Girgih
    Department of Human Nutritional Sciences and the Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg, MB, R3T 2N2, Canada
    Plant Foods Hum Nutr 68:39-46. 2013
  6. doi Blood pressure lowering effect of a pea protein hydrolysate in hypertensive rats and humans
    Huan Li
    Department of Human Nutritional Sciences and the Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg, Manitoba, Canada R3T 2N2
    J Agric Food Chem 59:9854-60. 2011
  7. doi Quantitative structure-activity relationship modeling of renin-inhibiting dipeptides
    Chibuike C Udenigwe
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB, R3T 2N2, Canada
    Amino Acids 42:1379-86. 2012
  8. ncbi Quantitative structure-activity relationship study of bitter di- and tri-peptides including relationship with angiotensin I-converting enzyme inhibitory activity
    Jianping Wu
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, R3T 2N2, Canada
    J Pept Sci 13:63-9. 2007
  9. ncbi Structural modulation of calmodulin and calmodulin-dependent protein kinase II by pea protein hydrolysates
    Huan Li
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
    Int J Food Sci Nutr 57:178-89. 2006
  10. doi Amino acid composition and antioxidant properties of pea seed ( Pisum sativum L.) enzymatic protein hydrolysate fractions
    Trisha L Pownall
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba R3T2N2, Canada
    J Agric Food Chem 58:4712-8. 2010

Collaborators

Detail Information

Publications28

  1. doi Emulsifying and foaming properties of commercial yellow pea (Pisum sativum L.) seed flours
    Rotimi E Aluko
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada R3T 2N2
    J Agric Food Chem 57:9793-800. 2009
    ..These results showed that PPI had generally significantly higher (p < 0.05) emulsion and foam forming properties than SPI, and that pea starch could be used to improve the quality of SPI-stabilized food emulsions...
  2. ncbi Technology for the production and utilization of food protein-derived anti-hypertensive peptides: a review
    Rotimi E Aluko
    Department of Human Nutritional Sciences and the Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg, Manitoba, R3T 2N2, Canada
    Recent Pat Biotechnol 1:260-7. 2007
    ..Finally, protein hydrolysates or peptide fractions that have hypotensive ability may then be used to formulate foods, beverages or pills that can be taken as therapeutic tools against hypertension...
  3. ncbi Determination of nutritional and bioactive properties of peptides in enzymatic pea, chickpea, and mung bean protein hydrolysates
    Rotimi E Aluko
    University of Manitoba, Department of Human Nutritional Sciences and the Richardson Centre for Functional Foods and Nutraceuticals, Winnipeg, MB, Canada
    J AOAC Int 91:947-56. 2008
    ..Also reviewed are the production and evaluation of activity of hypoallergenic peptides that may offer protection against anaphylactic reactions. The 3 main proteins discussed are chickpea, mung bean, and field pea...
  4. ncbi Multifunctional cationic peptide fractions from flaxseed protein hydrolysates
    Chibuike C Udenigwe
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada
    Plant Foods Hum Nutr 67:1-9. 2012
    ....
  5. doi Reverse-phase HPLC separation of hemp seed (Cannabis sativa L.) protein hydrolysate produced peptide fractions with enhanced antioxidant capacity
    Abraham T Girgih
    Department of Human Nutritional Sciences and the Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg, MB, R3T 2N2, Canada
    Plant Foods Hum Nutr 68:39-46. 2013
    ..In conclusion, the antioxidant activity of HPH after simulated GIT digestion is mainly influenced by the amino acid composition of some of its peptides...
  6. doi Blood pressure lowering effect of a pea protein hydrolysate in hypertensive rats and humans
    Huan Li
    Department of Human Nutritional Sciences and the Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg, Manitoba, Canada R3T 2N2
    J Agric Food Chem 59:9854-60. 2011
    ..Therefore, thermolysin derived bioactive peptides from PPH reduced blood pressure in hypertensive rats and human subjects, likely via effects on the renal angiotensin system...
  7. doi Quantitative structure-activity relationship modeling of renin-inhibiting dipeptides
    Chibuike C Udenigwe
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB, R3T 2N2, Canada
    Amino Acids 42:1379-86. 2012
    ..Therefore, IW may be a useful template for the development of advanced forms of highly active low molecular size antihypertensive peptides and peptidomimetics...
  8. ncbi Quantitative structure-activity relationship study of bitter di- and tri-peptides including relationship with angiotensin I-converting enzyme inhibitory activity
    Jianping Wu
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, R3T 2N2, Canada
    J Pept Sci 13:63-9. 2007
    ..However, there was no significant (p > 0.05) correlation between bitterness of di- and tri-peptides and their angiotensin I-converting enzyme-inhibitory properties...
  9. ncbi Structural modulation of calmodulin and calmodulin-dependent protein kinase II by pea protein hydrolysates
    Huan Li
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
    Int J Food Sci Nutr 57:178-89. 2006
    ..We concluded that the presence of the pea protein hydrolysates led to rearrangement of the native protein structure and exposure of buried hydrophobic groups of CaM and/or CaMKII...
  10. doi Amino acid composition and antioxidant properties of pea seed ( Pisum sativum L.) enzymatic protein hydrolysate fractions
    Trisha L Pownall
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba R3T2N2, Canada
    J Agric Food Chem 58:4712-8. 2010
    ..05) ability to inhibit linoleic acid oxidation and chelate metals. In contrast, glutathione had significantly higher (p < 0.05) free radical scavenging properties than the peptide fractions...
  11. ncbi Effect of cationic flaxseed protein hydrolysate fractions on the in vitro structure and activity of calmodulin-dependent endothelial nitric oxide synthase
    Adetayo O Omoni
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
    Mol Nutr Food Res 50:958-66. 2006
    ..We concluded that ability of the protein hydrolysate fractions to change the secondary and tertiary structures of CaM may explain their ability to reduce activity of CaM-dependent eNOS...
  12. doi Angiotensin-converting enzyme inhibition and free-radical scavenging properties of cationic peptides derived from soybean protein hydrolysates
    Vahid Farzamirad
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
    Int J Food Sci Nutr 59:428-37. 2008
    ..We concluded that fraction 3 had the most potential to be used as a bioactive ingredient because of its strong ACE-inhibitory and free-radical scavenging properties...
  13. ncbi Structural requirements of Angiotensin I-converting enzyme inhibitory peptides: quantitative structure-activity relationship study of di- and tripeptides
    Jianping Wu
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, R3T 2N2, Canada
    J Agric Food Chem 54:732-8. 2006
    ..The predicted peptides were synthesized, and their IC50 values were validated through laboratory determination of inhibition of ACE activity...
  14. doi Food protein-derived bioactive peptides: production, processing, and potential health benefits
    Chibuike C Udenigwe
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB, Canada
    J Food Sci 77:R11-24. 2012
    ....
  15. doi Antioxidant and angiotensin converting enzyme-inhibitory properties of a flaxseed protein-derived high Fischer ratio peptide mixture
    Chibuike C Udenigwe
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada
    J Agric Food Chem 58:4762-8. 2010
    ....
  16. ncbi Bitter taste receptor T2R1 is activated by dipeptides and tripeptides
    Jasbir Upadhyaya
    Department of Oral Biology, University of Manitoba, Winnipeg, Canada MB R3E 0W4
    Biochem Biophys Res Commun 398:331-5. 2010
    ..The ligand binding pocket in T2R1 is present on the extracellular surface of the receptor, and is formed by the transmembrane helices 1, 2, 3 and 7 and with extracellular loops 1 and 2 forming a cap like structure on the binding pocket...
  17. ncbi Restriction of the in vitro formation of angiotensin II by leucinyl-arginyl-tryptophan, a novel peptide with potent angiotensin I-converting enzyme inhibitory activity
    Jianping Wu
    Department of Human Nutritional Sciences, University of Manitoba, Canada
    Biosci Biotechnol Biochem 70:1277-80. 2006
    ....
  18. ncbi Kinetics of renin inhibition by sodium houttuyfonate analogs
    Lujiang Yuan
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
    Biosci Biotechnol Biochem 70:2275-80. 2006
    ..Kinetic studies with SHA-14 indicated a linear mixed-type of enzyme inhibition with a Ki value of 45.35 microM. It was concluded that the SHAs constitute potentially useful ingredients for the formulation of antihypertensive products...
  19. doi Distinctive effects of plant protein sources on renal disease progression and associated cardiac hypertrophy in experimental kidney disease
    Harold M Aukema
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Canada
    Mol Nutr Food Res 55:1044-51. 2011
    ..The inclusion of other plant protein sources could enhance compliance of intervention diets, but the effects of other plant protein sources are not known...
  20. doi Novel indole alkaloids from Nauclea latifolia and their renin-inhibitory activities
    Anthony A Agomuoh
    Department of Biology, Richardson College for the Environmental and Science Complex, The University of Winnipeg, 599 Portage Ave, Winnipeg, MB, Canada R3B 2G3
    Chem Biodivers 10:401-10. 2013
    ..Compound 1 has a 20-ethylidenetetrahydrofuran ring incorporated in its structure and represents the first example of this class of indole alkaloids. All of the isolates exhibited moderate in vitro renin inhibitory activities...
  21. ncbi Kinetics of the inhibition of calcium/calmodulin-dependent protein kinase II by pea protein-derived peptides
    Huan Li
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Canada
    J Nutr Biochem 16:656-62. 2005
    ..The results suggest that it may be possible to use pea protein-derived cationic peptides to modulate CaMKII activities...
  22. ncbi Identification and inhibitory properties of multifunctional peptides from pea protein hydrolysate
    Huan Li
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Canada R3T 2N2
    J Agric Food Chem 58:11471-6. 2010
    ..In general, the peptides had higher potency against ACE than against renin. It is indicated from our results that these peptides may be used as potential ingredients to formulate multifunctional food products and nutraceuticals. ..
  23. doi In vitro antioxidant properties of chicken skin enzymatic protein hydrolysates and membrane fractions
    John O Onuh
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada
    Food Chem 150:366-73. 2014
    ..We conclude that CSPHs and their peptide fractions may be used as ingredients in the formulation of functional foods and nutraceuticals for the control and management of oxidative stress-related diseases. ..
  24. pmc Chemometric analysis of the amino Acid requirements of antioxidant food protein hydrolysates
    Chibuike C Udenigwe
    The Department of Human Nutritional Sciences and the Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg, MB R3T 2N2, Canada E mail
    Int J Mol Sci 12:3148-61. 2011
    ..We conclude that information presented in this work could support the development of low cost methods that will efficiently generate potent antioxidant peptide mixtures from food proteins without the need for costly peptide purification...
  25. doi Potential of resveratrol in anticancer and anti-inflammatory therapy
    Chibuike C Udenigwe
    Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
    Nutr Rev 66:445-54. 2008
    ..Resveratrol has been shown to produce no adverse effects, even when consumed at high concentrations. Hence, resveratrol possesses good potential to be used as an adjunctive or alternative therapy for cancer and inflammatory diseases...
  26. doi Angiotensin I converting enzyme-inhibitory peptides from commercial wet- and dry-milled corn germ
    Nicholas Parris
    Eastern Regional Research Center, Agricultural Research Service, U S Department of Agriculture, 600 East Mermaid Lane, Wyndmoor, Pennsylvania 19038, USA
    J Agric Food Chem 56:2620-3. 2008
    ....
  27. ncbi Size of the aliphatic chain of sodium houttuyfonate analogs determines their affinity for renin and angiotensin I converting enzyme
    Lujiang Yuan
    Chemistry Institute of Pharmaceutical Resources, Southwest University, Chongqing 400716, People s Republic of China
    Int J Biol Macromol 41:274-80. 2007
    ..The results showed that renin is a more sensitive target than ACE for the potential antihypertensive ability of SHAs...
  28. ncbi Characterization of a calcium-soluble protein fraction from yellow mustard (Sinapis alba) seed meal with potential application as an additive to calcium-rich drinks
    Rotimi E Aluko
    Agriculture and Agri Food Canada, 107 Science Place, Saskatoon, Saskatchewan S7N 0X2, Canada
    J Agric Food Chem 52:6030-4. 2004
    ..We suggest that the S. alba CSPI could be used to prepare calcium-fortified high protein liquid products. However, the presence of allergenic proteins in this extract may limit its widespread food use...