W Ted Allison
Affiliation: University of Alberta
Leighton P, Kanyo R, Neil G, Pollock N, Allison W. Prion gene paralogs are dispensable for early zebrafish development and have nonadditive roles in seizure susceptibility. J Biol Chem. 2018;293:12576-12592 pubmed publisher
Allison W. The intrigue is infectious: Impacts of prion protein during neural development. Dev Biol. 2018;441:1-3 pubmed publisher
..for prion protein opens new avenues to understand the evolution of prion protein: what history led to a CNS protein that is conserved and abundant paradoxically being both dispensable for life and the template for devastating disease? ..
Allison W, Barthel L, Skebo K, Takechi M, Kawamura S, Raymond P. Ontogeny of cone photoreceptor mosaics in zebrafish. J Comp Neurol. 2010;518:4182-95 pubmed publisher
..These observations provide baseline data for understanding the development of cone mosaics via comparative analysis of larval and adult cone development in a model species. ..
Kim J, Yang H, Oel A, Brooks M, Jia L, Plachetzki D, et al
. Recruitment of Rod Photoreceptors from Short-Wavelength-Sensitive Cones during the Evolution of Nocturnal Vision in Mammals. Dev Cell. 2016;37:520-32 pubmed publisher
..We propose that this developmental mechanism allowed the adaptive exploitation of scotopic niches during the nocturnal bottleneck early in mammalian evolution. ..
Allison W, Duval M, Nguyen Phuoc K, Leighton P. Reduced Abundance and Subverted Functions of Proteins in Prion-Like Diseases: Gained Functions Fascinate but Lost Functions Affect Aetiology. Int J Mol Sci. 2017;18: pubmed publisher
..We propose experiments to uniquely test these ideas. ..