S M H Alibhai

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Long-term side effects of androgen deprivation therapy in men with non-metastatic prostate cancer: a systematic literature review
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Canada
    Crit Rev Oncol Hematol 60:201-15. 2006
  2. doi request reprint A pilot phase II RCT of a home-based exercise intervention for survivors of AML
    Shabbir M H Alibhai
    Department of Medicine, University Health Network, Toronto, ON, Canada
    Support Care Cancer 22:881-9. 2014
  3. doi request reprint Changes in bone mineral density in men starting androgen deprivation therapy and the protective role of vitamin D
    S M H Alibhai
    Department of Medicine, University Health Network, Room EN14 214, 200 Elizabeth Street, Toronto, M5G 2C4, Ontario, Canada
    Osteoporos Int 24:2571-9. 2013
  4. pmc Cardiac and cognitive effects of androgen deprivation therapy: are they real?
    S M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, ON
    Curr Oncol 17:S55-64. 2010
  5. pmc A clinical trial of supervised exercise for adult inpatients with acute myeloid leukemia (AML) undergoing induction chemotherapy
    Shabbir M H Alibhai
    Department of Medicine, University Health Network, Toronto, ON, Canada
    Leuk Res 36:1255-61. 2012
  6. ncbi request reprint Rethinking 30-day mortality risk after radical prostatectomy
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Ontario, Canada
    Urology 68:1057-60. 2006
  7. ncbi request reprint The impact of acute myeloid leukemia and its treatment on quality of life and functional status in older adults
    Shabbir M H Alibhai
    Department of Medicine, University Health Network, Toronto, Canada
    Crit Rev Oncol Hematol 64:19-30. 2007
  8. doi request reprint Impact of androgen deprivation therapy on cardiovascular disease and diabetes
    Shabbir M H Alibhai
    University Health Network, Room EN14 214, 200 Elizabeth St, Toronto, Ontario, Canada, M5G 2C4
    J Clin Oncol 27:3452-8. 2009
  9. doi request reprint Is there an optimal comorbidity index for prostate cancer?
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Ontario, Canada
    Cancer 112:1043-50. 2008
  10. doi request reprint Impact of hospital and surgeon volume on mortality and complications after prostatectomy
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Urol 180:155-62; discussion 162-3. 2008

Collaborators

Detail Information

Publications52

  1. ncbi request reprint Long-term side effects of androgen deprivation therapy in men with non-metastatic prostate cancer: a systematic literature review
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Canada
    Crit Rev Oncol Hematol 60:201-15. 2006
    ..Further insight into adverse effects of ADT and strategies to minimize these adverse effects await data from ongoing studies...
  2. doi request reprint A pilot phase II RCT of a home-based exercise intervention for survivors of AML
    Shabbir M H Alibhai
    Department of Medicine, University Health Network, Toronto, ON, Canada
    Support Care Cancer 22:881-9. 2014
    ..Although trials in patients with various solid tumors have reported improved fatigue and QOL following exercise interventions, there have been no studies in AML patients post treatment...
  3. doi request reprint Changes in bone mineral density in men starting androgen deprivation therapy and the protective role of vitamin D
    S M H Alibhai
    Department of Medicine, University Health Network, Room EN14 214, 200 Elizabeth Street, Toronto, M5G 2C4, Ontario, Canada
    Osteoporos Int 24:2571-9. 2013
    ..Vitamin D use was associated with improved BMD in the lumbar spine and in the first year...
  4. pmc Cardiac and cognitive effects of androgen deprivation therapy: are they real?
    S M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, ON
    Curr Oncol 17:S55-64. 2010
    ..Conflicting data in both areas have led to controversy and confusion. Here, we review published data in an attempt to clarify those issues...
  5. pmc A clinical trial of supervised exercise for adult inpatients with acute myeloid leukemia (AML) undergoing induction chemotherapy
    Shabbir M H Alibhai
    Department of Medicine, University Health Network, Toronto, ON, Canada
    Leuk Res 36:1255-61. 2012
    ..These results provide a foundation for a randomized trial to better understand the impact of exercise during IC on clinically important outcomes...
  6. ncbi request reprint Rethinking 30-day mortality risk after radical prostatectomy
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Ontario, Canada
    Urology 68:1057-60. 2006
    ..Although radical prostatectomy (RP) is associated with greater 30-day mortality in older men, the magnitude of the excess risk in older age groups compared with younger ones has not been well characterized...
  7. ncbi request reprint The impact of acute myeloid leukemia and its treatment on quality of life and functional status in older adults
    Shabbir M H Alibhai
    Department of Medicine, University Health Network, Toronto, Canada
    Crit Rev Oncol Hematol 64:19-30. 2007
    ..Receiving IC does not appear to lead to worse QOL or functional status than more palliative approaches. This information may aid treatment discussions in older patients with AML...
  8. doi request reprint Impact of androgen deprivation therapy on cardiovascular disease and diabetes
    Shabbir M H Alibhai
    University Health Network, Room EN14 214, 200 Elizabeth St, Toronto, Ontario, Canada, M5G 2C4
    J Clin Oncol 27:3452-8. 2009
    ..CONCLUSION Continuous ADT use for at least 6 months in older men is associated with an increased risk of diabetes and fragility fracture but not AMI or sudden cardiac death...
  9. doi request reprint Is there an optimal comorbidity index for prostate cancer?
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Ontario, Canada
    Cancer 112:1043-50. 2008
    ..Comorbidity is an important consideration in oncology practice, particularly among older patients. Although a variety of comorbidity indices have been employed in research studies, it is unclear whether any one index is preferred...
  10. doi request reprint Impact of hospital and surgeon volume on mortality and complications after prostatectomy
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Urol 180:155-62; discussion 162-3. 2008
    ..We determined whether hospital or surgeon volumes impacted various short-term surgical complications...
  11. doi request reprint Quality of life beyond 6 months after diagnosis in older adults with acute myeloid leukemia
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Canada
    Crit Rev Oncol Hematol 69:168-74. 2009
    ..This information may aid discussions with patients about treatment...
  12. doi request reprint Major 30-day complications after radical radiotherapy: a population-based analysis and comparison with surgery
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Ontario, Canada
    Cancer 115:293-302. 2009
    ..Few population-based studies have reported on the rates of major short-term complications that lead to hospitalization after radiotherapy...
  13. doi request reprint Levels of sex hormones have limited effect on cognition in older men with or without prostate cancer
    S M H Alibhai
    Department of Medicine, University Health Network, Canada
    Crit Rev Oncol Hematol 73:167-75. 2010
    ..Although cognitive function was not generally related to sex hormone levels in older men, there may be a weak association with working memory. These results may help guide future studies...
  14. doi request reprint Outcomes and quality of care in acute myeloid leukemia over 40 years
    Shabbir M H Alibhai
    Department of Medicine, University Health Network, Toronto, Ontario, Canada
    Cancer 115:2903-11. 2009
    ..Acute myeloid leukemia (AML) is associated with a poor prognosis, particularly in older patients. To the authors' knowledge, few population-based studies of AML treatment patterns and outcomes exist to date...
  15. doi request reprint Impact of androgen-deprivation therapy on physical function and quality of life in men with nonmetastatic prostate cancer
    Shabbir M H Alibhai
    University Health Network, Toronto, Ontario, Canada
    J Clin Oncol 28:5038-45. 2010
    ..This prospective longitudinal study evaluated the effect of androgen deprivation therapy (ADT) on objective and self-reported physical function...
  16. doi request reprint Fracture types and risk factors in men with prostate cancer on androgen deprivation therapy: a matched cohort study of 19,079 men
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology and Osteoporosis Program, University Health Network, Toronto, Ontario, Canada
    J Urol 184:918-23. 2010
    ..One study suggested that androgen deprivation therapy may also be associated with nonfragility fractures in older men. Whether other clinical risk factors independently increase the risk of fractures is not certain...
  17. doi request reprint Impact of androgen-deprivation therapy on cognitive function in men with nonmetastatic prostate cancer
    Shabbir M H Alibhai
    University Health Network, Toronto, Ontario, Canada
    J Clin Oncol 28:5030-7. 2010
    ..To evaluate the effects of androgen-deprivation therapy (ADT) on cognitive function in men with nonmetastatic prostate cancer (PC)...
  18. ncbi request reprint Cancer screening: the importance of outcome measures
    Shabbir M H Alibhai
    Department of Medicine, University of Toronto, Toronto, Canada M5G 2C4
    Crit Rev Oncol Hematol 57:215-24. 2006
    ....
  19. ncbi request reprint Do older men benefit from curative therapy of localized prostate cancer?
    Shabbir M H Alibhai
    University Health Network, Room ENG 233, 200 Elizabeth St, Toronto, Ontario, Canada M5G 2C4
    J Clin Oncol 21:3318-27. 2003
    ....
  20. ncbi request reprint Is there age bias in the treatment of localized prostate carcinoma?
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Ontario, Canada
    Cancer 100:72-81. 2004
    ..Previous studies have evaluated the influence of age and comorbidity, but to the authors' knowledge not RLE, on actual treatment decisions...
  21. ncbi request reprint 30-day mortality and major complications after radical prostatectomy: influence of age and comorbidity
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Canada
    J Natl Cancer Inst 97:1525-32. 2005
    ..Prior studies have suggested an increased risk of short-term complications among older men who underwent radical prostatectomy, but these studies did not adjust for comorbidity...
  22. ncbi request reprint The association between patient age and prostate cancer stage and grade at diagnosis
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, 200 Elizabeth Street, Toronto, Ontario M50 2C4, Canada
    BJU Int 94:303-6. 2004
    ..To investigate the association of age with prostate cancer stage and grade, as the latter factors at the time of diagnosis influence management and prognosis, with some studies suggesting that they may change as a function of patient age...
  23. ncbi request reprint Examining the location and cause of death within 30 days of radical prostatectomy
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, University of Toronto, Canada
    BJU Int 95:541-4. 2005
    ....
  24. pmc An approach to the management of unintentional weight loss in elderly people
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Ont
    CMAJ 172:773-80. 2005
    ..Screening tools to detect malnutrition are highlighted, and nonpharmacologic and pharmacologic strategies to minimize or reverse weight loss in older adults are discussed...
  25. ncbi request reprint Prevention and management of osteoporosis in men receiving androgen deprivation therapy: a survey of urologists and radiation oncologists
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Ontario, Canada
    Urology 68:126-31. 2006
    ..To determine the current practice of clinicians in the diagnosis and management of osteoporosis among men taking androgen deprivation therapy (ADT), because ADT leads to decreased bone mineral density (BMD) and fractures...
  26. doi request reprint Health-related quality of life anticipated with different management strategies for febrile neutropenia in adult cancer patients
    O Teuffel
    Division of Haematology Oncology, The Hospital for Sick Children, Toronto, Canada
    Support Care Cancer 20:2755-64. 2012
    ..To describe anticipated health-related quality of life (HRQL) for different hypothetical strategies of febrile neutropenia (FN) management in adult cancer patients...
  27. doi request reprint Older age is associated with similar quality of life and physical function compared to younger age during intensive chemotherapy for acute myeloid leukemia
    H Mohamedali
    Princess Margaret Hospital, University Health Network, Toronto, Canada
    Leuk Res 36:1241-8. 2012
    ..Compared to younger adults, older adults tolerate intensive chemotherapy quite well from QOL and physical function perspectives...
  28. doi request reprint Do quality of life or physical function at diagnosis predict short-term outcomes during intensive chemotherapy in AML?
    N Timilshina
    Department of Medicine, University Health Network, Toronto
    Ann Oncol 25:883-8. 2014
    ..We investigated the association between baseline QOL and physical function with short-term treatment outcomes in adults and elderly AML patients...
  29. ncbi request reprint Impact of androgen deprivation therapy on physical and cognitive function, as well as quality of life of patients with nonmetastatic prostate cancer
    F Joly
    Department of Medical Oncology and Hematology, Princess Margaret Hospital, University of Toronto, 610 University Avenue, Toronto, Ontario, Canada
    J Urol 176:2443-7. 2006
    ..We compared physical and cognitive function, and quality of life in a cross-sectional study of 57 patients receiving androgen deprivation therapy for nonmetastatic prostate cancer and 51 healthy age matched controls...
  30. doi request reprint Outpatient management of cancer patients with febrile neutropenia: a systematic review and meta-analysis
    O Teuffel
    Division of Haematology Oncology, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
    Ann Oncol 22:2358-65. 2011
    ..Our objective was to evaluate the current level of evidence before supporting widespread adoption of outpatient management for this population...
  31. ncbi request reprint The ten-year rule revisited: accuracy of clinicians' estimates of life expectancy in patients with localized prostate cancer
    Murray D Krahn
    Department of Medicine, University of Toronto School of Medicine, Toronto, Ontario, Canada
    Urology 60:258-63. 2002
    ....
  32. doi request reprint An update on a systematic review of the use of geriatric assessment for older adults in oncology
    M T E Puts
    Lawrence S Bloomberg Faculty of Nursing, University of Toronto, Toronto
    Ann Oncol 25:307-15. 2014
    ..g. treatment decision impact, treatment toxicity, mortality, use of care)...
  33. ncbi request reprint Continued undertreatment of older men with localized prostate cancer
    Kevin L Schwartz
    University of Toronto, School of Medicine, Toronto, Ontario, Canada
    Urology 62:860-5. 2003
    ..To explore the association among patient factors (age, comorbidity), disease-specific factors (stage, Gleason score), and suboptimal initial treatment in a cohort of men with localized prostate cancer...
  34. pmc Health-related quality of life anticipated with different management strategies for paediatric febrile neutropaenia
    S Cheng
    Department of Paediatrics, University of Toronto, 27 King s College Circle, Toronto, Ontario, Canada M5S 1A1
    Br J Cancer 105:606-11. 2011
    ..To describe (1) anticipated health-related quality of life during different strategies for febrile neutropaenia (FN) management and (2) attributes of those preferring inpatient management...
  35. doi request reprint Development, implementation, and evaluation of an Interprofessional Falls Prevention Program for older adults
    Carol Banez
    University Health Network, Toronto, Canada
    J Am Geriatr Soc 56:1549-55. 2008
    ..Persistent improvements were found in participants' balance, strength, functional mobility, and fear of falling. Patient satisfaction with the program was high. Challenges faced in program implementation are also highlighted...
  36. ncbi request reprint A systematic review of randomized trials in localized prostate cancer
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Ontario, Canada
    Can J Urol 11:2110-7. 2004
    ..We reviewed all published randomized trials that compared different primary treatment modalities for localized prostate cancer...
  37. pmc Use of geriatric assessment for older adults in the oncology setting: a systematic review
    M T E Puts
    Lawrence S Bloomberg Faculty of Nursing, University of Toronto, Toronto, ON, Canada
    J Natl Cancer Inst 104:1133-63. 2012
    ....
  38. doi request reprint Cost-effectiveness analysis of immediate radical cystectomy versus intravesical Bacillus Calmette-Guerin therapy for high-risk, high-grade (T1G3) bladder cancer
    Girish S Kulkarni
    Division of Urology, Department of Surgical Oncology, University Health Network, Toronto, Ontario, Canada
    Cancer 115:5450-9. 2009
    ..Because bladder cancer is the most expensive malignancy to treat per patient, decisions regarding the optimal treatment strategy should consider costs...
  39. ncbi request reprint Radical prostatectomy for early prostate cancer improves long term survival
    Shabbir M H Alibhai
    Department of Medicine, University Health Network, Toronto Rehabilitation Institute, Canada
    Cancer Treat Rev 31:640-3. 2005
  40. doi request reprint Adolescents with acute lymphoblastic leukemia treated at pediatric versus adult hospitals
    J D Pole
    Pediatric Oncology Group of Ontario, Toronto, Canada
    Ann Oncol 24:801-6. 2013
    ..The objective was to compare 5-year overall survival (OS) between adolescent and young adult (AYA) patients (age 15-19) with acute lymphoblastic leukemia (ALL) treated at a pediatric versus an adult center...
  41. doi request reprint Effect of whole-body vibration on BMD: a systematic review and meta-analysis
    L Slatkovska
    Osteoporosis Program, University Health Network Mount Sinai Hospital, Toronto, ON, Canada
    Osteoporos Int 21:1969-80. 2010
    ....
  42. doi request reprint Troubling outcomes from population-level analysis of surgery for upper tract urothelial carcinoma
    Robert Abouassaly
    Division of Urologic Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Urology 76:895-901. 2010
    ..Complete nephroureterectomy is the standard of care, and increasing evidence has shown that a suboptimal surgical technique is associated with an adverse prognosis...
  43. ncbi request reprint Meta-analysis: effect of prophylactic hematopoietic colony-stimulating factors on mortality and outcomes of infection
    Lillian Sung
    Division of Haematology Oncology, The University of Toronto, The Hospital for Sick Children, and University Health Network, Toronto, Ontario, Canada
    Ann Intern Med 147:400-11. 2007
    ..Benefits of prophylactic hematopoietic colony-stimulating factors (CSFs) in adults and children receiving cancer chemotherapy or undergoing stem-cell transplantation (SCT) are unclear...
  44. doi request reprint Validation of the triage risk stratification tool to identify older persons at risk for hospital admission and returning to the emergency department
    Jacques S Lee
    Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada
    J Am Geriatr Soc 56:2112-7. 2008
    ..To assess the predictive validity of the Triage Risk Stratification Tool (TRST) to identify return to the emergency department (ED) or hospitalization in a multicenter patient sample...
  45. doi request reprint Associations between quality of life, fatigue, and cytokine levels in patients aged 50+ with acute myeloid leukemia
    Abbas H Panju
    Department of Medicine, University Health Network, Toronto General Hospital, 200 Elizabeth Street EN14 214, Toronto, Ontario M5G 2C4, Canada
    Support Care Cancer 17:539-46. 2009
    ..Cytokines, biomarkers of inflammation, may moderate both health outcomes, but published data are limited. We looked at the role of cytokines in modulating QOL and fatigue in an older AML population...
  46. doi request reprint Management of decreased bone mineral density in men starting androgen-deprivation therapy for prostate cancer
    Abbas H Panju
    Department of Medicine, University Health Network, Toronto, Ontario, Canada
    BJU Int 103:753-7. 2009
    ....
  47. doi request reprint Healthcare costs associated with prostate cancer: estimates from a population-based study
    Murray D Krahn
    Department of Medicine, University of Toronto, Toronto, Canada
    BJU Int 105:338-46. 2010
    ..Health Economic (multiway sensitivity analyses)...
  48. doi request reprint Information needs of adult patients 50 or older with newly diagnosed acute myeloid leukemia
    T Yogaparan
    Department of Medicine, Baycrest Centre for Geriatric Care, University Health Network, University of Toronto, Toronto, Canada
    Leuk Res 33:1288-90. 2009
    ..The majority of patients preferred a passive or collaborative decision-making role. Almost half the patients did not know their estimated 6-month prognosis, and 17% felt it was 90% or better...
  49. pmc Optimal management of high-risk T1G3 bladder cancer: a decision analysis
    Girish S Kulkarni
    Division of Urology, Department of Surgical Oncology, University of Toronto, Toronto, Ontario, Canada
    PLoS Med 4:e284. 2007
    ..We estimated life expectancy (LE) and quality-adjusted life expectancy (QALE) for both of these treatments for men and women of different ages and comorbidity levels...
  50. pmc The effect of English language proficiency on length of stay and in-hospital mortality
    Ava John-Baptiste
    Division of General Internal Medicine, Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Gen Intern Med 19:221-8. 2004
    ..In ambulatory care settings, patients with limited English proficiency receive lower quality of care. Limited information is available describing outcomes for inpatients...
  51. ncbi request reprint A review and meta-analysis of prostate cancer utilities
    Karen E Bremner
    Toronto General Research Institute University Health Network, Canada
    Med Decis Making 27:288-98. 2007
    ..Health-related quality of life is a key issue in prostate cancer (PC) management. The authors summarized published utilities for common health-related quality of life outcomes of PC and determined how methodological factors affect them...
  52. pmc Waiting times for cancer surgery
    Shabbir M H Alibhai
    CMAJ 166:710; author reply 710-1. 2002