Ayub Akbari

Summary

Affiliation: University of Ottawa
Country: Canada

Publications

  1. pmc Change in appropriate referrals to nephrologists after the introduction of automatic reporting of the estimated glomerular filtration rate
    Ayub Akbari
    Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario
    CMAJ 184:E269-76. 2012
  2. ncbi request reprint Reference intervals for anion gap and strong ion difference in pregnancy: a pilot study
    Ayub Akbari
    Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Hypertens Pregnancy 26:111-9. 2007
  3. ncbi request reprint Detection of chronic kidney disease with laboratory reporting of estimated glomerular filtration rate and an educational program
    Ayub Akbari
    Department of Medicine, University of Ottawa, Ontario, Canada
    Arch Intern Med 164:1788-92. 2004
  4. doi request reprint Reporting of the estimated glomerular filtration rate was associated with increased use of angiotensin-converting enzyme inhibitors and angiotensin-II receptor blockers in CKD
    Arsh K Jain
    London Kidney Chemical Research Unit, Division of Nephrology, Department of Medicine, London Health Science Center, University of Western Ontario, London, Canada
    Kidney Int 81:1248-53. 2012
  5. pmc Quality of cardiovascular disease care in Ontario, Canada: missed opportunities for prevention - a cross sectional study
    Clare Liddy
    C T Lamont Primary Health Care Research Centre, Bruyère Research Institute, Ottawa, ON, Canada
    BMC Cardiovasc Disord 12:74. 2012
  6. doi request reprint Effect of clinical variables and immunosuppression on serum cystatin C and beta-trace protein in kidney transplant recipients
    Christine A White
    Department of Medicine, Division of Nephrology, Queen s University, Kingston, Canada
    Am J Kidney Dis 54:922-30. 2009
  7. doi request reprint Estimating GFR using serum beta trace protein: accuracy and validation in kidney transplant and pediatric populations
    Christine A White
    Division of Nephrology, Department of Medicine, Queen s University, Kingston, Ontario, Canada
    Kidney Int 76:784-91. 2009
  8. ncbi request reprint Chronic kidney disease stage in renal transplantation classification using cystatin C and creatinine-based equations
    Christine White
    Division of Nephrology, Queen s University, Kingston, Ontario, Canada
    Nephrol Dial Transplant 22:3013-20. 2007
  9. ncbi request reprint A novel equation to estimate glomerular filtration rate using beta-trace protein
    Christine A White
    Division of Nephrology, Department of Medicine, Queen s University, Kingston, Canada
    Clin Chem 53:1965-8. 2007
  10. ncbi request reprint Estimating glomerular filtration rate in kidney transplantation: a comparison between serum creatinine and cystatin C-based methods
    Christine White
    Division of Nephrology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    J Am Soc Nephrol 16:3763-70. 2005

Detail Information

Publications34

  1. pmc Change in appropriate referrals to nephrologists after the introduction of automatic reporting of the estimated glomerular filtration rate
    Ayub Akbari
    Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario
    CMAJ 184:E269-76. 2012
    ..We hypothesized that such reporting, along with an ad hoc educational component for primary care physicians, would increase the number of appropriate referrals...
  2. ncbi request reprint Reference intervals for anion gap and strong ion difference in pregnancy: a pilot study
    Ayub Akbari
    Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Hypertens Pregnancy 26:111-9. 2007
    ..Acid-base status and electrolyte levels change in normal pregnancy. We hypothesized that these physiological changes affect both anion gap and strong ion difference (SID)...
  3. ncbi request reprint Detection of chronic kidney disease with laboratory reporting of estimated glomerular filtration rate and an educational program
    Ayub Akbari
    Department of Medicine, University of Ottawa, Ontario, Canada
    Arch Intern Med 164:1788-92. 2004
    ..We hypothesized that laboratory reporting of estimated glomerular filtration rate (GFR) accompanied with an educational intervention would improve recognition of chronic kidney disease (CKD)...
  4. doi request reprint Reporting of the estimated glomerular filtration rate was associated with increased use of angiotensin-converting enzyme inhibitors and angiotensin-II receptor blockers in CKD
    Arsh K Jain
    London Kidney Chemical Research Unit, Division of Nephrology, Department of Medicine, London Health Science Center, University of Western Ontario, London, Canada
    Kidney Int 81:1248-53. 2012
    ..Thus, eGFR reporting contributes to improved, guideline-appropriate care of older patients with CKD...
  5. pmc Quality of cardiovascular disease care in Ontario, Canada: missed opportunities for prevention - a cross sectional study
    Clare Liddy
    C T Lamont Primary Health Care Research Centre, Bruyère Research Institute, Ottawa, ON, Canada
    BMC Cardiovasc Disord 12:74. 2012
    ..We examined primary care practice adherence to recommended care guidelines associated with the prevention and management of CVD for high risk patients...
  6. doi request reprint Effect of clinical variables and immunosuppression on serum cystatin C and beta-trace protein in kidney transplant recipients
    Christine A White
    Department of Medicine, Division of Nephrology, Queen s University, Kingston, Canada
    Am J Kidney Dis 54:922-30. 2009
    ..The aim of this study is to examine the independent effect of various clinical parameters on serum concentrations of creatinine, cystatin C, and BTP in kidney transplant recipients...
  7. doi request reprint Estimating GFR using serum beta trace protein: accuracy and validation in kidney transplant and pediatric populations
    Christine A White
    Division of Nephrology, Department of Medicine, Queen s University, Kingston, Ontario, Canada
    Kidney Int 76:784-91. 2009
    ..These results were an improvement compared to the MDRD and Schwartz equations, both of which had high median bias and reduced accuracy. The updated Schwartz equation also performed well...
  8. ncbi request reprint Chronic kidney disease stage in renal transplantation classification using cystatin C and creatinine-based equations
    Christine White
    Division of Nephrology, Queen s University, Kingston, Ontario, Canada
    Nephrol Dial Transplant 22:3013-20. 2007
    ..However, creatinine-based equations are inaccurate in RTRs leading to frequent CKD stage misclassification. It is not known whether the classification of CKD stage would be improved using a cystatin C-based estimate of GFR...
  9. ncbi request reprint A novel equation to estimate glomerular filtration rate using beta-trace protein
    Christine A White
    Division of Nephrology, Department of Medicine, Queen s University, Kingston, Canada
    Clin Chem 53:1965-8. 2007
    ..The utility of BTP has been limited by the lack of an equation to translate BTP into an estimate of GFR. The objectives of this study were to develop a BTP-based GFR estimation equation...
  10. ncbi request reprint Estimating glomerular filtration rate in kidney transplantation: a comparison between serum creatinine and cystatin C-based methods
    Christine White
    Division of Nephrology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    J Am Soc Nephrol 16:3763-70. 2005
    ..Further prospective studies with repetitive measurement of cystatin C are needed to determine whether cystatin C-based estimates of GFR will be sufficiently accurate to monitor long-term allograft function...
  11. ncbi request reprint Cystatin-C and beta trace protein as markers of renal function in pregnancy
    Ayub Akbari
    Kidney Research Centre, Ottawa, Ontario, Canada
    BJOG 112:575-8. 2005
    ..To assess the validity of Cystatin-C (Cys-C) and beta trace protein (BTP) as clinical markers of glomerular filtration rate (GFR) in pregnant women...
  12. ncbi request reprint Serum creatinine is an inadequate screening test for renal failure in elderly patients
    Peter J Swedko
    Division of Nephrology, The Ottawa Hospital, Riverside Campus, 1967 Riverside Dr, Ottawa, Ontario, Canada K1H 7W9
    Arch Intern Med 163:356-60. 2003
    ..If so, this would lead to underrecognition and thus suboptimal care of patients with severe renal failure...
  13. doi request reprint Accuracy of cystatin C-based estimates of glomerular filtration rate in kidney transplant recipients: a systematic review
    Gavin Harman
    Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Nephrol Dial Transplant 28:741-57. 2013
    ..The overall performance of cystatin C-based equations in kidney transplantation is unclear with conflicting results between studies...
  14. ncbi request reprint Spot urine protein measurements: are these accurate in kidney transplant recipients?
    Ayub Akbari
    Division of Nephrology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Transplantation 94:389-95. 2012
    ..Aside from tests of correlation, there has been little evaluation of these measurements in kidney transplantation...
  15. doi request reprint Use of kidney function end points in kidney transplant trials: a systematic review
    Christine A White
    Division of Nephrology, Department of Medicine, Queen s University, Kingston, Ontario, Canada
    Am J Kidney Dis 56:1140-57. 2010
    ..The frequency and type of kidney function end points used are unknown...
  16. doi request reprint Estimating glomerular filtration rate in kidney transplantation: is the new chronic kidney disease epidemiology collaboration equation any better?
    Christine A White
    Division of Nephrology, Department of Medicine, Queen s University, Kingston, Ontario, Canada
    Clin Chem 56:474-7. 2010
    ..The performance of the new equation for kidney transplant recipients (KTRs) is unknown...
  17. ncbi request reprint Chronic kidney disease management: comparison between renal transplant recipients and nontransplant patients with chronic kidney disease
    Ayub Akbari
    Division of Nephrology, Department of Medicine, University of Ottawa, Ottawa, Ont, Canada
    Nephron Clin Pract 107:c7-13. 2007
    ..It is not known how the management of CKD in RTR differs from that of patients with native CKD. This study compares the management of complications related to CKD between RTR and patients with native CKD...
  18. ncbi request reprint Spot urine protein measurements in kidney transplantation: a systematic review of diagnostic accuracy
    Ayub Akbari
    Division of Nephrology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Nephrol Dial Transplant 29:919-26. 2014
    ..Recent guidelines have recommended quantification of proteinuria by spot protein-to-creatinine ratio (PCR) or spot albumin-to-creatinine ratio (ACR). Validity of spot measurements remains unclear in renal transplant recipients...
  19. ncbi request reprint Beta-trace protein, cystatin C, beta(2)-microglobulin, and creatinine compared for detecting impaired glomerular filtration rates in children
    Guido Filler
    Departments of Pediatrics, Children s Hospital of Eastern Ontario, Ottawa, Ontario, K1H 8L1 Canada
    Clin Chem 48:729-36. 2002
    ....
  20. pmc The impact of interlaboratory differences in cystatin C assay measurement on glomerular filtration rate estimation
    Christine A White
    Division of Nephrology, Department of Medicine, Queen s University, Kingston, Ontario, Canada
    Clin J Am Soc Nephrol 6:2150-6. 2011
    ..This study was designed to examine the differences in CysC and GFR estimation (eGFR) using Siemens' nephelometric immunoassay and the Mayo Clinic equation. The ability of the eGFRs to predict measured GFR was also examined...
  21. doi request reprint The estimation, measurement, and relevance of the glomerular filtration rate in stage 5 chronic kidney disease
    Christine A White
    Division of Nephrology, Department of Medicine, Queen s University, Kingston, Kingston, Ontario, Canada
    Semin Dial 24:540-9. 2011
    ..This review will focus on the methods available to quantify GFR in stage 5 CKD and their use in both clinical and research settings...
  22. ncbi request reprint Combination therapy with an angiotensin receptor blocker and an ACE inhibitor in proteinuric renal disease: a systematic review of the efficacy and safety data
    Martin MacKinnon
    Department of Medicine, Division of Nephrology, University of Ottawa, Ottawa, Ontario, Canada
    Am J Kidney Dis 48:8-20. 2006
    ..Additional trials with longer follow-up are needed to determine whether the decrease in proteinuria will result in significant preservation of renal function...
  23. ncbi request reprint The effect of pentoxifylline on proteinuria in diabetic kidney disease: a meta-analysis
    Brendan B McCormick
    Division of Nephrology, Kidney Research Center, Ottawa Health Research Institute, Ottawa, Ontario, Canada
    Am J Kidney Dis 52:454-63. 2008
    ..Pentoxifylline is a potential therapeutic agent for diabetic kidney disease because it has anti-inflammatory, antifibrotic, and hemorheological properties...
  24. doi request reprint Performance of creatinine-based estimates of GFR in kidney transplant recipients: a systematic review
    Christine A White
    Department of Medicine, Division of Nephrology, Queen s University, Kingston, Ottawa, Ontario, Canada
    Am J Kidney Dis 51:1005-15. 2008
    ..The performance of these equations in kidney transplant recipients is unclear, with conflicting results between studies...
  25. pmc Improved delivery of cardiovascular care (IDOCC) through outreach facilitation: study protocol and implementation details of a cluster randomized controlled trial in primary care
    Clare Liddy
    C T Lamont Primary Health Care Research Centre, Elisabeth Bruyere Research Institute, Ottawa, Ontario, Canada
    Implement Sci 6:110. 2011
    ....
  26. doi request reprint When laboratories report estimated glomerular filtration rates in addition to serum creatinines, nephrology consults increase
    Arsh K Jain
    Division of Nephrology, Department of Medicine, University of Western Ontario, London, Ontario, Canada
    Kidney Int 76:318-23. 2009
    ..However, it remains to be seen whether the routine reporting of eGFR results in improved treatment and outcomes for those with chronic kidney disease...
  27. ncbi request reprint Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in peritoneal dialysis: systematic review and meta-analysis of randomized controlled trials
    Ayub Akbari
    Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Perit Dial Int 29:554-61. 2009
    ..Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are widely used in clinical practice. The safety and efficacy of these agents in peritoneal dialysis (PD) patients are unclear...
  28. ncbi request reprint The Cockcroft-Gault formula should not be used in children
    Guido Filler
    Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Canada
    Kidney Int 67:2321-4. 2005
    ..Although designed for adults, the Cockcroft-Gault formula was recently proposed for use in children > or =13 years of age...
  29. ncbi request reprint Measured creatinine clearance from timed urine collections substantially overestimates glomerular filtration rate in patients with liver cirrhosis: a systematic review and individual patient meta-analysis
    Normand L Proulx
    Department of Medicine, University of Western Ontario, London, Ontario N6A 4G5, Canada
    Nephrol Dial Transplant 20:1617-22. 2005
    ..The objective of this study was to review the accuracy of measured creatinine clearance (MCrCl) from timed urine collections for estimating true GFR...
  30. pmc Prevention of contrast-induced acute kidney injury: is simple oral hydration similar to intravenous? A systematic review of the evidence
    Swapnil Hiremath
    Division of Nephrology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    PLoS ONE 8:e60009. 2013
    ..For logistical ease, the oral route is an alternative to the intravenous. The objective of this study was to compare the efficacy of the oral to the intravenous route in prevention of contrast-induced acute kidney injury...
  31. doi request reprint Feasibility of providing nephrology services to remote communities with videoconferencing
    Manon Campbell
    Division of Nephrology, Department of Medicine, Ottawa Hospital, Ottawa, ON K1H 7W9, Canada
    J Telemed Telecare 18:13-6. 2012
    ..The analysis of staff hours worked showed almost no increase following the introduction of telemedicine. Telemedicine is therefore feasible for follow-up care of remote chronic kidney disease patients...
  32. pmc Pregnancy outcomes in women with chronic kidney disease: a systematic review
    Immaculate F Nevis
    Department of Medicine, University of Western Ontario, London, Ontario, Canada
    Clin J Am Soc Nephrol 6:2587-98. 2011
    ..Pregnant women with chronic kidney disease (CKD) are at risk of adverse maternal and fetal outcomes. We conducted a systematic review of observational studies that described this risk...
  33. ncbi request reprint Zopiclone-induced acute interstitial nephritis
    Naser Hussain
    Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Am J Kidney Dis 41:E17. 2003
    ..Kidney biopsy results showed acute interstitial nephritis with a prominent eosinophilic infiltrate in the interstitium. He recovered his renal function after stopping the medication and receiving corticosteroids...
  34. doi request reprint Cystatin C and residual renal function in patients on peritoneal dialysis
    Atul Mulay
    Am J Kidney Dis 52:194-5; author reply 195-6. 2008