Neill K J Adhikari

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. doi Self-reported symptoms of depression and memory dysfunction in survivors of ARDS
    Neill K J Adhikari
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada
    Chest 135:678-87. 2009
  2. pmc Acute kidney injury among critically ill patients with pandemic H1N1 influenza A in Canada: cohort study
    Sean M Bagshaw
    Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 3C1 12 Walter C Mackenzie Centre, 8440 112 St NW, Edmonton, AB T6G 2B7, Canada
    BMC Nephrol 14:123. 2013
  3. pmc Critical care resources in the Solomon Islands: a cross-sectional survey
    Mia Westcott
    George Institute For Global Health, PO Box M201, Missenden Road Sydney, NSW 2050, Australia
    BMC Int Health Hum Rights 12:1. 2012
  4. pmc Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2)
    Matthias Briel
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Trials 10:49. 2009
  5. doi Self-reported depressive symptoms and memory complaints in survivors five years after ARDS
    Neill K J Adhikari
    Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada
    Chest 140:1484-93. 2011
  6. doi High-frequency oscillation in adults: a utilization review
    Neill K J Adhikari
    Department of Critical Care Medicine and the Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Canada
    Crit Care Med 39:2631-44. 2011
  7. pmc The use of wireless e-mail to improve healthcare team communication
    Chris O'Connor
    Department of Critical Care Medicine, Room D1 08, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, Canada M4N3M5
    J Am Med Inform Assoc 16:705-13. 2009
  8. doi Consent in critical care trials: a survey of Canadian research ethics boards and critical care researchers
    Mark Duffett
    McMaster Children s Hospital, Hamilton, Ontario, Canada
    J Crit Care 26:533.e11-22. 2011
  9. ncbi Epidemiology of acute kidney injury in Canadian critical care units: a prospective cohort study
    Ayodele Odutayo
    Division of Nephrology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    Can J Anaesth 59:934-42. 2012
  10. doi Knowledge translation interventions for critically ill patients: a systematic review*
    Tasnim Sinuff
    1Department of Critical Care Medicine, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada 2Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada 3Department of Medicine, Queen s University, Kingston, ON, Canada 4Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, ON, Canada 5Department of Critical Care Medicine, University of Calgary and Alberta Health Services, Calgary, AB, Canada 6Department of Medicine, University of Calgary and Alberta Health Services, Calgary, AB, Canada 7Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada 8Institute of Public Health, University of Calgary, Calgary, AB, Canada 9Center for Health Evaluation and Outcome Sciences, Vancouver, BC, Canada 10Department of Medicine, Providence Health Care and University of British Columbia, Vancouver, BC, Canada 11Department of Medicine, McMaster University, Hamilton, ON, Canada 12Department of Clinical Epidemiology and Biostatistics, Japan
    Crit Care Med 41:2627-40. 2013

Detail Information

Publications57

  1. doi Self-reported symptoms of depression and memory dysfunction in survivors of ARDS
    Neill K J Adhikari
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada
    Chest 135:678-87. 2009
    ..Survivors of ARDS have well documented physical limitations, but psychological effects are less clear. We determined the prevalence of self-reported depression and memory dysfunction in ARDS survivors...
  2. pmc Acute kidney injury among critically ill patients with pandemic H1N1 influenza A in Canada: cohort study
    Sean M Bagshaw
    Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 3C1 12 Walter C Mackenzie Centre, 8440 112 St NW, Edmonton, AB T6G 2B7, Canada
    BMC Nephrol 14:123. 2013
    ..Our objective was to describe the incidence of AKI (acute kidney injury) in these patients and risk factors for AKI, renal replacement therapy (RRT), and mortality...
  3. pmc Critical care resources in the Solomon Islands: a cross-sectional survey
    Mia Westcott
    George Institute For Global Health, PO Box M201, Missenden Road Sydney, NSW 2050, Australia
    BMC Int Health Hum Rights 12:1. 2012
    ..abstract:..
  4. pmc Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2)
    Matthias Briel
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Trials 10:49. 2009
    ..The aim of STOPIT-2 is to determine the magnitude and determinants of possible bias introduced by stopping RCTs early for benefit...
  5. doi Self-reported depressive symptoms and memory complaints in survivors five years after ARDS
    Neill K J Adhikari
    Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada
    Chest 140:1484-93. 2011
    ..Survivors of ARDS report depressive symptoms and memory complaints, the prevalence of which after 5 years is unknown...
  6. doi High-frequency oscillation in adults: a utilization review
    Neill K J Adhikari
    Department of Critical Care Medicine and the Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Canada
    Crit Care Med 39:2631-44. 2011
    ..Given the uncertain benefits, our objective was to describe contemporary patient selection, high-frequency oscillation utilization, and outcomes...
  7. pmc The use of wireless e-mail to improve healthcare team communication
    Chris O'Connor
    Department of Critical Care Medicine, Room D1 08, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, Canada M4N3M5
    J Am Med Inform Assoc 16:705-13. 2009
    ..To assess the impact of using wireless e-mail for clinical communication in an intensive care unit (ICU)...
  8. doi Consent in critical care trials: a survey of Canadian research ethics boards and critical care researchers
    Mark Duffett
    McMaster Children s Hospital, Hamilton, Ontario, Canada
    J Crit Care 26:533.e11-22. 2011
    ..We compared the attitudes and beliefs of Canadian research ethics boards (REBs) and intensive care unit researchers toward the use of various consent models for a low-risk randomized controlled trial...
  9. ncbi Epidemiology of acute kidney injury in Canadian critical care units: a prospective cohort study
    Ayodele Odutayo
    Division of Nephrology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    Can J Anaesth 59:934-42. 2012
    ..We undertook this study to characterize the epidemiology of acute kidney injury (AKI) in Canadian critical care units. We aimed to identify predictors of mortality for patients diagnosed with AKI...
  10. doi Knowledge translation interventions for critically ill patients: a systematic review*
    Tasnim Sinuff
    1Department of Critical Care Medicine, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada 2Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada 3Department of Medicine, Queen s University, Kingston, ON, Canada 4Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, ON, Canada 5Department of Critical Care Medicine, University of Calgary and Alberta Health Services, Calgary, AB, Canada 6Department of Medicine, University of Calgary and Alberta Health Services, Calgary, AB, Canada 7Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada 8Institute of Public Health, University of Calgary, Calgary, AB, Canada 9Center for Health Evaluation and Outcome Sciences, Vancouver, BC, Canada 10Department of Medicine, Providence Health Care and University of British Columbia, Vancouver, BC, Canada 11Department of Medicine, McMaster University, Hamilton, ON, Canada 12Department of Clinical Epidemiology and Biostatistics, Japan
    Crit Care Med 41:2627-40. 2013
    ..We systematically reviewed ICU-based knowledge translation studies to assess the impact of knowledge translation interventions on processes and outcomes of care...
  11. doi Critical care and the global burden of critical illness in adults
    Neill K J Adhikari
    Interdepartmental Division of Critical Care, University of Toronto and Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    Lancet 376:1339-46. 2010
    ....
  12. doi Quality of professional society guidelines and consensus conference statements in critical care
    Tasnim Sinuff
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada
    Crit Care Med 36:1049-58. 2008
    ..To examine the quality of professional society critical care guidelines and consensus statements...
  13. doi High frequency oscillation in patients with acute lung injury and acute respiratory distress syndrome (ARDS): systematic review and meta-analysis
    Sachin Sud
    Critical Care Medicine Program, Interdepartmental Division of Critical Care, University of Toronto, Toronto General Hospital, 585 University Ave, Toronto, ON, Canada, M5G 2N2
    BMJ 340:c2327. 2010
    ..To determine clinical and physiological effects of high frequency oscillation compared with conventional ventilation in patients with acute lung injury/acute respiratory distress syndrome (ARDS)...
  14. doi Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia: systematic review and meta-analysis
    Sachin Sud
    Interdepartmental Division of Critical Care, University of Toronto, Toronto, Canada
    Intensive Care Med 36:585-99. 2010
    ..Prone position ventilation for acute hypoxemic respiratory failure (AHRF) improves oxygenation but not survival, except possibly when AHRF is severe...
  15. doi Worldwide demand for critical care
    Neill K J Adhikari
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre and Interdepartmental Division of Critical Care, University of Toronto, Toronto, Ontario, Canada
    Curr Opin Crit Care 17:620-5. 2011
    ..Interest in the global burden of critical illness is growing, but comprehensive data to describe this burden and the resources available to provide care for critically ill patients are lacking...
  16. doi Early massive transfusion in trauma patients: Canadian single-centre retrospective cohort study
    Tushar D Mahambrey
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Can J Anaesth 56:740-50. 2009
    ..To determine associations between red blood cell (RBC) transfusion and early and late clinical outcomes in massively transfused adult trauma patients...
  17. pmc Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis
    Neill K J Adhikari
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada
    BMJ 334:779. 2007
    ....
  18. doi High-frequency ventilation versus conventional ventilation for treatment of acute lung injury and acute respiratory distress syndrome
    Sachin Sud
    Division of Critical Care, Department of Medicine, Trillium Health Center, University of Toronto, Mississauga, Canada
    Cochrane Database Syst Rev 2:CD004085. 2013
    ..This review was originally published in 2004 and was updated in 2011...
  19. doi Timing the initiation of renal replacement therapy for acute kidney injury in Canadian intensive care units: a multicentre observational study
    Edward Clark
    Kidney Research Centre, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada
    Can J Anaesth 59:861-70. 2012
    ..Defining current practice is necessary to design interventional trials. We describe the current Canadian practice regarding the timing of RRT initiation for AKI...
  20. doi The design and interpretation of pilot trials in clinical research in critical care
    Donald M Arnold
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Crit Care Med 37:S69-74. 2009
    ..The objective of this review is to highlight the importance of randomized pilot trials and to describe key features of their design and interpretation using examples from critical care...
  21. doi Electronic prescribing in an ambulatory care setting: a cluster randomized trial
    Katie N Dainty
    St Michael s Hospital, Toronto, ON, Canada
    J Eval Clin Pract 18:761-7. 2012
    ..Medication errors resulting in preventable adverse drug events most commonly occur at the ordering stage. Electronic prescribing may prevent such errors but its impact has not been rigorously evaluated...
  22. ncbi Abstract reporting in randomized clinical trials of acute lung injury: an audit and assessment of a quality of reporting score
    Karen E A Burns
    Graduate Program in Health Research Methodology, McMaster University, Hamilton, Ontario, Canada
    Crit Care Med 33:1937-45. 2005
    ..To evaluate the quality of reporting among abstracts of randomized controlled trials (RCTs) in acute lung injury and to highlight important trial information for abstract inclusion...
  23. pmc Pressure and volume limited ventilation for the ventilatory management of patients with acute lung injury: a systematic review and meta-analysis
    Karen E A Burns
    Interdepartmental Division of Critical Care, University of Toronto, Toronto, Canada
    PLoS ONE 6:e14623. 2011
    ..We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing pressure and volume-limited (PVL) ventilation strategies with more traditional mechanical ventilation in adults with ALI and ARDS...
  24. doi Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis
    Dirk Bassler
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    JAMA 303:1180-7. 2010
    ..Theory and simulation suggest that randomized controlled trials (RCTs) stopped early for benefit (truncated RCTs) systematically overestimate treatment effects for the outcome that precipitated early stopping...
  25. ncbi Mortality predictions in the intensive care unit: comparing physicians with scoring systems
    Tasnim Sinuff
    Department of Critical Care Medicine, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Crit Care Med 34:878-85. 2006
    ..Our systematic review compared the accuracy of ICU physicians' and scoring system predictions of ICU or hospital mortality of critically ill adults...
  26. doi Noninvasive ventilation for acute respiratory failure near the end of life
    Tasnim Sinuff
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Crit Care Med 36:789-94. 2008
    ....
  27. doi A multifaceted intervention for quality improvement in a network of intensive care units: a cluster randomized trial
    Damon C Scales
    Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada
    JAMA 305:363-72. 2011
    ..Evidence-based practices improve intensive care unit (ICU) outcomes, but eligible patients may not receive them. Community hospitals treat most critically ill patients but may have few resources dedicated to quality improvement...
  28. doi Medical admission order sets to improve deep vein thrombosis prophylaxis rates and other outcomes
    Chris O'Connor
    Department of Medicine, Trillium Health Centre, Mississauga, Ontario, Canada
    J Hosp Med 4:81-9. 2009
    ..The value of order sets for clinical decision support has not been established...
  29. doi Has mortality from acute respiratory distress syndrome decreased over time?: A systematic review
    Jason Phua
    F R C P C, Toronto Western Hospital, 399 Bathurst Street, 2MCL 411M, Toronto, ON M5T 2S8, Canada
    Am J Respir Crit Care Med 179:220-7. 2009
    ..It is commonly stated that mortality from acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) is decreasing...
  30. pmc A guide for the design and conduct of self-administered surveys of clinicians
    Karen E A Burns
    Interdepartmental Division of Critical Care, University of Toronto, and Keenan Research Centre and the Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ont
    CMAJ 179:245-52. 2008
  31. doi Pay for performance in the intensive care unit--opportunity or threat?
    Kristina Khanduja
    Department of Anaesthesia, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Crit Care Med 37:852-8. 2009
    ..Our objective was to describe these programs and their potential implementation in intensive care units (ICUs)...
  32. pmc Utility and safety of draining pleural effusions in mechanically ventilated patients: a systematic review and meta-analysis
    Ewan C Goligher
    Interdepartmental Division of Critical Care, Mount Sinai Hospital and the University Health Network, University of Toronto, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada
    Crit Care 15:R46. 2011
    ..Pleural effusions are frequently drained in mechanically ventilated patients but the benefits and risks of this procedure are not well established...
  33. pmc Use of non-invasive ventilation to wean critically ill adults off invasive ventilation: meta-analysis and systematic review
    Karen E A Burns
    Interdepartmental Division of Critical Care, St Michael s Hospital, Toronto, ON, Canada M5B 1W8
    BMJ 338:b1574. 2009
    ..To summarise the evidence for early extubation with immediate application of non-invasive ventilation compared with continued invasive weaning on important outcomes in intubated adults with respiratory failure...
  34. pmc Effect of mechanical ventilation in the prone position on clinical outcomes in patients with acute hypoxemic respiratory failure: a systematic review and meta-analysis
    Sachin Sud
    Interdepartmental Division of Critical Care, University of Toronto, Faculty of Science, Toronto, Ont
    CMAJ 178:1153-61. 2008
    ..We sought to determine the effect of mechanical ventilation in the prone position on mortality, oxygenation, duration of ventilation and adverse events in patients with acute hypoxemic respiratory failure...
  35. doi Inhaled nitric oxide does not reduce mortality in patients with acute respiratory distress syndrome regardless of severity: systematic review and meta-analysis*
    Neill K J Adhikari
    1Department of Critical Care Medicine and Sunnybrook Research Institute, Sunnybrook Health Sciences Centre and University of Toronto, Toronto, ON, Canada 2Division of Critical Care Medicine, Department of Medicine, Cooper University Hospital, Camden, NJ 3Department of Anesthesia and Intensive Care, Sahlgrenska University Hospital, Gothenburg, Sweden 4Department of Critical Care and Anesthesiology and SAMU, Hopital Lariboisiere, Universite Paris 7 Denis Diderot, Paris, France 5Department of Anesthesiology and Intensive Care Medicine, University Hospital of Lille, Lille, France 6Departments for Anesthesia, Intensive Care Medicine, and Pain Management, Vivantes Klinikum Neukoelln, Berlin, Germany 7Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine, Suwon, South Korea 8Department of Medicine, Mount Sinai Hospital and University of Toronto, Toronto ON, Canada 9The Keenan Research Centre in the Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto ON, Canada 10Departments of Critical Care and Medicine, The Keenan Research Centre in the Li Ka Shing Knowledge Institute, St Michael s Hospital and University of Toronto, Toronto, ON, Canada
    Crit Care Med 42:404-12. 2014
    ....
  36. doi Update in critical care 2007
    Robert A Fowler
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada
    Am J Respir Crit Care Med 177:808-19. 2008
  37. pmc Survey of information technology in Intensive Care Units in Ontario, Canada
    Stephen E Lapinsky
    Intensive Care Unit, Mount Sinai Hospital, Toronto, Canada
    BMC Med Inform Decis Mak 8:5. 2008
    ..We surveyed ICUs in the province of Ontario, Canada, to determine the availability, implementation and variability of information systems...
  38. pmc The ratio of means method as an alternative to mean differences for analyzing continuous outcome variables in meta-analysis: a simulation study
    Jan O Friedrich
    Department of Medicine, University of Toronto, Toronto, Canada
    BMC Med Res Methodol 8:32. 2008
    ..SMD and RoM allow pooling of outcomes expressed in different units and comparisons of effect sizes across interventions, but RoM interpretation does not require knowledge of the pooled SD, a quantity generally unknown to clinicians...
  39. pmc Does intensive insulin therapy really reduce mortality in critically ill surgical patients? A reanalysis of meta-analytic data
    Jan O Friedrich
    Interdepartmental Division of Critical Care and Department of Medicine, University of Toronto, R, Fraser Elliot Building, 3rd Floor, South Wing, 3S 805, 190 Elizabeth Street, Toronto, Ontario, Canada
    Crit Care 14:324. 2010
    ..Further insights may come from individual patient data meta-analyses or from future large multicenter RCTs in more narrowly defined subgroups of surgical patients...
  40. pmc Clinical review: critical care in the global context--disparities in burden of illness, access, and economics
    Robert A Fowler
    Department of Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room D478, Toronto, ON, Canada M4N 3M5
    Crit Care 12:225. 2008
    ....
  41. doi Implementation of a research awareness program in the critical care unit: effects on families and clinicians
    Craig Dale
    Trauma, Emergency and Critical Care Program, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    Intensive Crit Care Nurs 26:69-74. 2010
    ..Successful conduct of research studies in the critically ill requires communication with families, substitute decision-makers and clinicians...
  42. ncbi Randomized trials stopped early for benefit: a systematic review
    Victor M Montori
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    JAMA 294:2203-9. 2005
    ..Their prevalence, the magnitude and plausibility of their treatment effects, and the extent to which they report information about how investigators decided to stop early are, however, unknown...
  43. doi Prophylactic magnesium for improving neurologic outcome after aneurysmal subarachnoid hemorrhage: systematic review and meta-analysis
    Eyal Golan
    Department of Medicine, University Health Network, Toronto, Ontario, Canada M5T 2S8
    J Crit Care 28:173-81. 2013
    ..Neurologic disability is common after aneurysmal subarachnoid hemorrhage (aSAH). Our objective was to systematically review the prophylactic use of magnesium to improve neurologic outcomes in these patients...
  44. pmc Rosiglitazone: can meta-analysis accurately estimate excess cardiovascular risk given the available data? Re-analysis of randomized trials using various methodologic approaches
    Jan O Friedrich
    Department of Medicine, University of Toronto, Toronto, Canada
    BMC Res Notes 2:5. 2009
    ..The objective of this study was to assess the robustness of the rosiglitazone results by using alternative reasonable methodologic approaches and by analyzing additional related outcomes...
  45. doi Ratio of geometric means to analyze continuous outcomes in meta-analysis: comparison to mean differences and ratio of arithmetic means using empiric data and simulation
    Jan O Friedrich
    Department of Medicine, University of Toronto, Toronto, Canada
    Stat Med 31:1857-86. 2012
    ....
  46. doi Previous cultures are not clinically useful for guiding empiric antibiotics in suspected ventilator-associated pneumonia: secondary analysis from a randomized trial
    Kevin M Sanders
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada M5T 2S8
    J Crit Care 23:58-63. 2008
    ..To examine the predictive validity of prior cultures at predicting the microorganism isolated at the time of suspicion of ventilator-associated pneumonia (VAP)...
  47. doi Ratio of means for analyzing continuous outcomes in meta-analysis performed as well as mean difference methods
    Jan O Friedrich
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    J Clin Epidemiol 64:556-64. 2011
    ..Ratio of means (RoM) is an alternative effect measure that performs comparably in simulation. We compared treatment effects and heterogeneity for RoM, MD, and SMD using empiric data...
  48. doi Real-time automated paging and decision support for critical laboratory abnormalities
    Edward Etchells
    Centre for Patient Safety, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, Canada
    BMJ Qual Saf 20:924-30. 2011
    ..For patients with critical laboratory abnormalities, timely clinical alerts with decision support could improve management and reduce adverse events...
  49. pmc Outcomes of interfacility critical care adult patient transport: a systematic review
    Eddy Fan
    Interdepartmental Division of Critical Care Medicine, University of Toronto, 399 Bathurst Street, F2 150, Toronto, Ontario, M5T 2S8, Canada
    Crit Care 10:R6. 2006
    ..We aimed to determine the adverse events and important prognostic factors associated with interfacility transport of intubated and mechanically ventilated adult patients...
  50. pmc Inclusion of zero total event trials in meta-analyses maintains analytic consistency and incorporates all available data
    Jan O Friedrich
    Interdepartmental Division of Critical Care, University of Toronto, Toronto, Canada
    BMC Med Res Methodol 7:5. 2007
    ..This study examined the influence of such trials on pooled treatment effects...
  51. ncbi Legislative barriers to outpatient e-prescribing in a randomized trial
    Sherman Quan
    Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario
    Healthc Q 10:106-10, 112. 2007
    ....
  52. pmc Drotrecogin alfa (activated): does current evidence support treatment for any patients with severe sepsis?
    Jan O Friedrich
    Interdepartmental Division of Critical Care, University of Toronto, Toronto, Ontario, Canada
    Crit Care 10:145. 2006
    ..Consequently, further randomised trials of this agent in prospectively defined high-risk patients are required to clarify its role in the management of severe sepsis...
  53. doi High-dose renal replacement therapy for acute kidney injury: Systematic review and meta-analysis
    Ryan Van Wert
    Department of Medicine, University of Toronto, Toronto, Canada
    Crit Care Med 38:1360-9. 2010
    ..To determine the effect of renal replacement therapy dose on mortality and dialysis dependence in patients with acute kidney injury...
  54. pmc Routine chest x-rays in intensive care units: a systematic review and meta-analysis
    Anusoumya Ganapathy
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto ON M4N 3M5, Canada
    Crit Care 16:R68. 2012
    ..Chest x-rays (CXRs) are the most frequent radiological tests performed in the intensive care unit (ICU). However, the utility of performing daily routine CXRs is unclear...
  55. ncbi Bilevel noninvasive positive pressure ventilation for acute respiratory failure: survey of Ontario practice
    Karen E A Burns
    Division of Critical Care Medicine, University of Western Ontario, London, Ontario, Canada
    Crit Care Med 33:1477-83. 2005
    ..To determine physicians' stated practices regarding the use of bilevel noninvasive ventilation (NIV) for acute respiratory failure and the predictors of practice variation...
  56. ncbi The evolution of intensive care unit performance assessment
    Marius Terblanche
    Department of Critical Care Medicine, B 702 Sunnybrook and Women s College Health Science Centre, Toronto, Ontario, Canada M4N 3M5
    J Crit Care 21:19-22. 2006
    ..Successful performance assessment requires the quantification of relevant indexes of performance. Although these indexes are increasingly being developed, it will be some time before widely recognized, validated systems are available...
  57. ncbi Maintaining allocation concealment: following your SNOSE
    Damon C Scales
    Interdepartmental Division of Critical Care, University of Toronto, Ontario, Canada
    J Crit Care 20:191-3. 2005