Research Topics
| Jean AddingtonSummaryAffiliation: University of Calgary Country: Canada Publications
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Detail Information
Publications
Affect recognition in people at clinical high risk of psychosisJean Addington
Department of Psychiatry, Faculty of Medicine, University of Calgary, Calgary AB, Canada
Schizophr Res 140:87-92. 2012..While poorer affect recognition may be associated with vulnerability for psychosis, the current results suggest that it may not be a marker of developing a psychotic illness...- North American Prodrome Longitudinal Study (NAPLS 2): overview and recruitmentJean Addington
Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada
Schizophr Res 142:77-82. 2012..This paper describes the overall methodology of the NAPLS-2 project and reports on the ascertainment and demographics at the midway point of the study with (360 CHR) and 180 controls... 
Prediction and prevention of psychosis in youth at clinical high riskJean Addington
Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Alberta, T2N 4N1, Canada
Annu Rev Clin Psychol 8:269-89. 2012..Next, treatment studies are reviewed. The review concludes with a framework for future early identification and treatment studies...
Cognitive behavioral therapy in prodromal psychosisJean Addington
Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Alberta, Canada
Curr Pharm Des 18:558-65. 2012..Relatively few trials have been completed and this paper reviews the existing trials. Implications of these trials for the treatment of this early phase as well as for designing future studies are discussed...- Using the brief core schema scales with individuals at clinical high risk of psychosisJean Addington
Universities of Calgary and Toronto, Canada
Behav Cogn Psychother 37:227-31. 2009..They provide a more useful measure of schemata about self and others than traditional measures of self-esteem... - At clinical high risk for psychosis: outcome for nonconvertersJean Addington
Centre for Mental Health Research and Education, University of Calgary, 3280 Hospital Dr, NW, Calgary, Alberta T2N 4Z6
Am J Psychiatry 168:800-5. 2011..Less is known about the outcome among this group, referred to as false positive individuals... - Three-year outcome of treatment in an early psychosis programJean Addington
Department of Psychiatry, Alberta Centennial Mental Health Research Chair, Calgary, Alberta
Can J Psychiatry 54:626-30. 2009..Little is known about the follow-up arrangements offered to patients when their time in a FEP comes to an end... - A randomized controlled trial of cognitive behavioral therapy for individuals at clinical high risk of psychosisJean Addington
Department of Psychiatry, University of Calgary, Alberta, Canada
Schizophr Res 125:54-61. 2011.... - Outcome after discharge from an early psychosis programJean Addington
Department of Psychiatry, University of Calgary, Calgary, Canada
Schizophr Res 106:363-6. 2008..Results were that, although there was no further improvement in positive symptoms, there was continued improvement in social functioning and signs of improvement in negative symptoms... - Cognitive-behavioral therapy for individuals at high risk of developing psychosisJean Addington
Department of Psychiatry, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N4N1, Canada
J Clin Psychol 65:879-90. 2009..Cognitive behavioral therapy (CBT) has been tested as a potentially effective intervention in this group. Here, we describe two cases that were treated with CBT... - Neurocognitive and social functioning in schizophrenia: a 2.5 year follow-up studyJ Addington
Department of Psychiatry, University of Calgary, Foothills Hospital, Alberta, Calgary, Canada
Schizophr Res 44:47-56. 2000..Verbal ability, verbal memory and vigilance were significant predictors of social problem solving as assessed by the AIPSS. Results suggest that the association between neurocognition and social functioning remains consistent over time... - Symptom remission in first episode patientsJean Addington
Department of Psychiatry, University of Calgary, Calgary, Canada
Schizophr Res 106:281-5. 2008.... - Impact of an early psychosis program on substance useJ Addington
Department of Psychiatry, The University of Calgary, Alberta, Canada
Psychiatr Rehabil J 25:60-7. 2001..This paper describes our 2-year experience with an integrated approach to reduce substance use in a specialized treatment program for individuals experiencing a first episode of psychosis... - Cognitive functioning in first-episode schizophreniaJean Addington
Department of Psychiatry, University of Calgary, Calgary, Alta
J Psychiatry Neurosci 27:188-92. 2002..To compare the cognitive functioning of a sample of patients experiencing their first episode of schizophrenia with that of patients with an established schizophrenia illness... - Negative symptoms in individuals at clinical high risk of psychosisDanijela Piskulic
Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada
Psychiatry Res 196:220-4. 2012..Thus, early and persistent negative symptoms may represent a vulnerability for risk of developing psychosis... - Predictors of disengagement from treatment in an early psychosis programJacqueline Stowkowy
Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Alberta, Canada
Schizophr Res 136:7-12. 2012..The purpose of this study is to determine the rate of disengagement from a three year FE treatment program and the predictors of disengagement... - Patterns of premorbid functioning in first-episode psychosis: initial presentationJean Addington
Department of Psychiatry, University of Calgary, Calgary, AB, Canada
Schizophr Res 62:23-30. 2003.... - Social functioning in individuals at clinical high risk for psychosisJean Addington
Department of Psychiatry, University of Toronto, Toronto, Canada
Schizophr Res 99:119-24. 2008.... - Social and cognitive functioning in psychosisJean Addington
Department of Psychiatry, University of Toronto, Toronto, Canada
Schizophr Res 99:176-81. 2008..This study supports the association between cognition and social functioning but indicates that this is a function of how social functioning is conceptualized and assessed... - Serum monitoring of antipsychotic drug levels during concomitant administration of sertraline and antipsychotic medicationKathleen Pierson
Department of Psychiatry, University of Calgary, Foothills Hospital, Alberta
Can J Psychiatry 51:715-8. 2006..To assess whether pharmacokinetic drug interactions occur when sertraline is added to antipsychotic medications... - Outcome of a first episode of psychosis in adolescence: a 2-year follow-upAlissa Pencer
Department of Psychology, University of Calgary, Calgary, Alberta, Canada
Psychiatry Res 133:35-43. 2005..These adolescents are doing relatively well following their first episode and reinforce the need to address cannabis use as an integral part of a comprehensive treatment program... - Treating young individuals at clinical high risk for psychosisCatherine Marshall
Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada
Early Interv Psychiatry 6:60-8. 2012..Few studies have followed those who do not go on to develop a psychotic illness... - The course of cognitive functioning in first episode psychosis: changes over time and impact on outcomeJean Addington
Department of Psychiatry, University of Toronto, Toronto, Canada
Schizophr Res 78:35-43. 2005..Finally there are implications for improved methodology in the assessment of both cognitive and social functioning... - Facial affect recognition: a mediator between cognitive and social functioning in psychosis?Jean Addington
Department of Psychiatry, University of Toronto, Canada
Schizophr Res 85:142-50. 2006..This 1-year longitudinal study tested the hypothesis that facial affect recognition mediates the relationship between cognitive and social functioning... - Substance use and cognition in early psychosisAlissa Pencer
Department of Psychology, University of Calgary, Calgary, Alta
J Psychiatry Neurosci 28:48-54. 2003..However, substance use may have other detrimental effects on the process of the psychotic illness... - Cognitive functioning in first episode psychosis: initial presentationJean Addington
Department of Psychiatry, University of Calgary, Foothills Hospital, Calgary, Canada
Schizophr Res 62:59-64. 2003..There was no evidence to support differences in cognition among the different schizophrenia spectrum diagnostic groups... - Diagnostic stability over one year in first-episode psychosisJean Addington
Department of Psychiatry, University of Toronto, Toronto, Canada
Schizophr Res 86:71-5. 2006..Schizophrenia can be reliably diagnosed at the initial assessment. There are clinical implications for dealing with the risk of shifting diagnosis for those who present with schizophrenia spectrum and other psychotic disorders... - The association between social anxiety and social functioning in first episode psychosisMarcia Voges
Department of Psychology, University of Calgary, Canada
Schizophr Res 76:287-92. 2005..D.=27.42). Results were that negative symptoms and negative self-statements, but not social anxiety, were significant predictors of social functioning. This has implications for addressing these negative cognitions in early psychosis... - Insight in early psychosis: a 1-year follow-upAlisa R Mintz
Department of Psychology, University of Calgary, Calgary, Alberta, Canada
Schizophr Res 67:213-7. 2004..Insight improved significantly over 12 months, and was negatively correlated with both positive and negative symptoms, and positively correlated with depressive symptoms at admission. There were no associations with cognition... - Using the global functioning social and role scales in a first-episode sampleDanijela Piskulic
Department of Psychiatry, University of Calgary, Calgary, AB, Canada
Early Interv Psychiatry 5:219-23. 2011..The purpose of this study was to determine if these measures would be useful in a first episode population... - Social cognition mediates illness-related and cognitive influences on social function in patients with schizophrenia-spectrum disordersJean Addington
Department of Psychiatry, University of Toronto, Toronto, Canada
J Psychiatry Neurosci 35:49-54. 2010..The objective of the current study was to use structural equation modelling to test the hypothesis that the relation between cognitive performance and social function is mediated by patients' social cognitive abilities... - Social cognition and negative symptoms in psychosisDanijela Piskulic
Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary AB, Canada
Psychiatry Res 188:283-5. 2011.... - Exploring the neural correlates of delusions of referenceMahesh Menon
Department of Psychiatry, University of Toronto, Toronto, Canada
Biol Psychiatry 70:1127-33. 2011..The cortical midline structures (CMS) and subcortical regions, including the amygdala and striatum, are linked with self-reference in healthy adults. Less is known about the neural substrates of altered self-reference in schizophrenia... - Early detection of psychosis: finding those at clinical high riskJean Addington
Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
Early Interv Psychiatry 2:147-53. 2008..The aim of this paper was to describe the development of a research clinic for individuals who appear to be at risk of developing a psychosis and the process for educating the community and obtaining referrals... - The promise of early interventionJean Addington
Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
Early Interv Psychiatry 1:294-307. 2007..However, there are still many unanswered issues which are in developing stages or which require further investigation... - Assessment of premorbid function in first-episode schizophrenia: modifications to the Premorbid Adjustment ScaleSarah Van Mastrigt
Departments of Psychiatry and Psychology, University of Calgary, Calgary, Alta
J Psychiatry Neurosci 27:92-101. 2002..Finally, we make recommendations to enhance the use of the PAS when evaluating patients who have experienced their first episode of schizophrenia... - The diagnosis and assessment of individuals prodromal for schizophrenic psychosisJean Addington
Department of Psychiatry, University of Toronto, Toronto, Canada
CNS Spectr 9:588-94. 2004..This article reviews and describes measures that are currently being used and further developed in order to determine both the diagnostic criteria for the prodromal state and the severity of these putatively prodromal symptoms... - Substance misuse at presentation to an early psychosis programSarah Van Mastrigt
Dept. of Psychiatry, University of Calgary, Calgary, Alberta, Canada
Soc Psychiatry Psychiatr Epidemiol 39:69-72. 2004..CONCLUSIONS: This study confirms the high rates of substance misuse, in particular cannabis, in first-episode psychosis. Implications for treatment are addressed... - The role of family work in early psychosisJean Addington
Department of Psychiatry, University of Toronto, Canada
Schizophr Res 79:77-83. 2005..Thus, thirdly we will describe a recovery model that has its origins in the Calgary First Episode Program and has since been expanded for use in the First Episode Psychosis Program in Toronto, Canada... - The course of cognitive functioning over six months in individuals at clinical high risk for psychosisMariapaola Barbato
Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Alberta, Canada
Psychiatry Res 206:195-9. 2013..Future longitudinal research should address if further decline takes place during the prodrome or after conversion to psychosis... - Performance measures for early psychosis treatment servicesDonald Addington
Department of Psychiatry, the University of Calgary in Alberta, Canada
Psychiatr Serv 56:1570-82. 2005..The requirements of the study were that the processes used to identify measures and gain consensus should be comprehensive, be reproducible, and reflect the perspective of multiple stakeholders in Canada... - Maladaptive schemas as a mediator between social defeat and positive symptoms in young people at clinical high risk for psychosisJacqueline Stowkowy
Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Alberta, Canada
Early Interv Psychiatry 6:87-90. 2012..The aim of this study was to examine whether negative beliefs about the self and others link social defeat to early signs of psychosis... - Double-blind, placebo-controlled comparison of the efficacy of sertraline as treatment for a major depressive episode in patients with remitted schizophreniaDonald Addington
Departments of Psychiatry, University of Calgary, Calgary, Alberta, Canada
J Clin Psychopharmacol 22:20-5. 2002..Testing the efficacy of widely accepted but poorly evaluated treatments should be a research priority. Future studies require a larger sample size and longer duration of treatment... - Youth at ultra high risk for psychosis: using the Revised Network Episode Model to examine pathways to mental health careKatherine M Boydell
Child Health Evaluative Sciences, The Hospital for Sick Children Departments of Psychiatry and Dalla Lana School of Public Health Lawrence S Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada
Early Interv Psychiatry 7:170-86. 2013..Understanding this process and the strategies that support positive early intervention on the part of youth and significant others is critical... - Pathways to care for those at clinical high risk of developing psychosisJacqueline Stowkowy
Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada
Early Interv Psychiatry 7:80-3. 2013....