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Genomes and Genes
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Publications
Incorporating linguistic, probabilistic, and possibilistic information in a risk-based approach for ranking contaminated sitesKejiang Zhang
Department of Civil Engineering, University of Calgary, Alberta, Canada
Integr Environ Assess Manag 6:711-24. 2010..This methodology can use the original site information directly as much as possible. The case study shows that this systematic methodology provides more reasonable results...
An ontology for Xenopus anatomy and developmentErik Segerdell
Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada
BMC Dev Biol 8:92. 2008..A controlled, structured vocabulary for Xenopus anatomy and development is essential for organizing these data...
Mind-body interventions in oncologyLinda E Carlson
Department of Psychosocial Resources, Tom Baker Cancer Centre Alberta Cancer Board, Holy Cross Site, Calgary, AB, Canada
Curr Treat Options Oncol 9:127-34. 2008....
Long chain fatty acid uptake in vivo: comparison of [125I]-BMIPP and [3H]-bromopalmitateJane Shearer
Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA
Lipids 43:703-11. 2008..Exercise preferentially exacerbates the breakdown of [3H]-BROMO, making [125I]-BMIPP the analogue of choice for prolonged (>30 min) experimental protocols with elevated metabolic demands...
Aldosterone and the autocrine modulation of potassium currents and oxidative stress in the diabetic rat heartY Shimoni
Department of Physiology and Biophysics, Health Sciences Centre, University of Calgary, Calgary, Alberta, Canada
Br J Pharmacol 154:675-87. 2008..Aldosterone plays a major role in cardiac pathology. This study was designed to investigate the role of cardiac aldosterone in modulating K(+) currents and oxidative stress in the streptozotocin-induced diabetic rat heart...
Within- and between-nervous-system inhibition of return: observation is as good as performanceTimothy N Welsh
Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada
Psychon Bull Rev 14:950-6. 2007..These results indicate that mirror neuron system may be involved in both higher-order and automatic cognitive behavior...
Role of viral infections in asthma and chronic obstructive pulmonary diseaseDavid Proud
Department of Physiology and Biophysics, University of Calgary, HSC 1627, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1 Canada
Am J Respir Cell Mol Biol 35:513-8. 2006..A better understanding of the mechanisms underlying viral modulation of these diseases, therefore, may lead to new therapeutic approaches...
Mental disorders in a population sample with musculoskeletal disordersScott B Patten
Department of Community Health Sciences, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada
BMC Musculoskelet Disord 7:37. 2006..One study reported an association between lifetime substance use disorders and arthritis...
Metabolic syndrome: a marker of patients at high cardiovascular riskDavid C W Lau
Department of Medicine, Julia McFarlane Diabetes Research Centre, Calgary, Alberta
Can J Cardiol 22:85B-90B. 2006..Given the prevalence of the metabolic syndrome and the exaggerated CVD risks, innovative therapeutic approaches continue to evolve...
Scrotal hair in identical twin infantsAlexander K C Leung
Department of Pediatrics, University of Calgary, Canada
Int J Dermatol 44:1042-4. 2005
Inhibition of thrombin-induced vascular endothelial growth factor production in human neuroblastoma (NB-1) cells by argatrobanKrishna Pada Sarker
Department of Laboratory and Vascular Medicine, Cardiovascular and Respiratory Disorders, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan
Pathophysiol Haemost Thromb 34:41-7. 2005..Here, it appears that argatroban may be effective in controlling disorders linked to thrombin-induced VEGF production in neuronal cells...
Applicant attraction to organizations and job choice: a meta-analytic review of the correlates of recruiting outcomesDerek S Chapman
Department of Psychology, University of Calgary, AB, Canada
J Appl Psychol 90:928-44. 2005..Path analyses showed that applicant attitudes and intentions mediated the predictor-job choice relationships. The authors discuss the implications of these findings for recruiting theory, research, and practice...
Should tendon and aponeurosis be considered in series?Marcelo Epstein
Department of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, Alta, Canada T2N 1N4
J Biomech 39:2020-5. 2006..Unfortunately, this requirement eliminates, for all but the simplest cases, a theoretical approach of muscle modeling based on intuitive free-body diagrams...
Hypertension surveillance in Canada: minimum standards for assessing blood pressure in surveysNorm R C Campbell
Department of Medicine, University of Calgary, Calgary, AB
Can J Public Health 96:217-20. 2005....
Diagnosis and treatment of dementia: 4. Approach to management of mild to moderate dementiaDavid B Hogan
Departments of Medicine and Clinical Neurosciences, University of Calgary, Calgary, Alta
CMAJ 179:787-93. 2008..In this article, we provide practical guidance on management based on recommendations from the Third Canadian Consensus Conference on the Diagnosis and Treatment of Dementia...
The evolving understanding of major depression epidemiology: implications for practice and policyScott B Patten
Department of Community Health Sciences and Hotchkiss Brain Institute, University of Calgary, Alberta
Can J Psychiatry 53:689-95. 2008..The objective of this commentary is to explore the implications of these new epidemiologic findings for policy and practice in Canada...
Diagnosis and treatment of dementia: 5. Nonpharmacologic and pharmacologic therapy for mild to moderate dementiaDavid B Hogan
Department of Clinical Neurosciences, Health Sciences Centre, University of Calgary, 3330 Hospital Dr NW, Calgary, ABT2N4N1
CMAJ 179:1019-26. 2008....
Proteinuria in childrenAlexander K C Leung
University of Calgary Faculty of Medicine, Calgary, Alberta, Canada
Am Fam Physician 82:645-51. 2010....
Computer-aided detection of architectural distortion in prior mammograms of interval cancerRangaraj M Rangayyan
Department of Electrical and Computer Engineering, Schulich School of Engineering, Calgary, AB T2N1N4, Canada
J Digit Imaging 23:611-31. 2010..80 at 7.6 false positives per image. The methods have good potential in detecting architectural distortion in mammograms of interval cancer cases...
Highly luminescent terpyridinyl-ethynyl functionalized dithieno[3,2-b:2',3'-d]phospholes: synthesis, properties and complexation behaviorDong Ren Bai
Department of Chemistry, University of Calgary, 2500 University Drive NW, Calgary, AB, CanadaT2N 1N4
Dalton Trans 39:1250-60. 2010....
Practice pattern variation in oral glucocorticoid therapy after the induction of response in proliferative lupus nephritisM Walsh
Department of Medicine, University of Calgary, Calgary, AB, Canada
Lupus 19:628-33. 2010..This variability likely represents clinical equipoise. A randomized trial evaluating the effect of glucocorticoid use after induction of response is warranted...
Predicting defibrillation outcome based on phase of ventricular activity during ICD implantationGo Suzuki
Electrical and Computer Engineering Department, University of Calgary, Alberta, Canada
Conf Proc IEEE Eng Med Biol Soc 2009:4759-62. 2009..78). From our results, timing of defibrillation shock attempt is not a factor in successful termination of VF for patients undergoing ICD implantation...
Time-frequency phase analysis of ictal EEG recordings with the S-transformC Robert Pinnegar
Department of Clinical Neurosciences, Foothills Medical Centre, University of Calgary, Calgary, AB, Canada
IEEE Trans Biomed Eng 56:2583-93. 2009..The differences between the recording times of spike-wave discharges at different electrodes exhibit behavior that is strongly dependent on time and frequency...
Cancer attractors: a systems view of tumors from a gene network dynamics and developmental perspectiveSui Huang
Institute for Biocomplexity and Informatics, Biological Sciences Bldg, University of Calgary, 2500 University Drive, Calgary AB, Canada
Semin Cell Dev Biol 20:869-76. 2009....
The Arctic as a model for anticipating, preventing, and mitigating climate change impacts on host-parasite interactionsSusan J Kutz
Department of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada T2N 4N1
Vet Parasitol 163:217-28. 2009....
Ecology of the gastrointestinal parasites of Colobus vellerosus at Boabeng-Fiema, Ghana: possible anthropozoonotic transmissionJulie A Teichroeb
Department of Anthropology, University of Calgary, Calgary, Alberta, Canada T2N 1N4
Am J Phys Anthropol 140:498-507. 2009..that morphologically resembled the human species I. belli. The presence of this parasite and G. duodenalis Assemblage B indicates possible anthropozoonotic and/or zoonotic transmission between humans and colobus monkeys at this site...
Ethnic variation in acute myocardial infarction presentation and access to careKathryn M King
Faculty of Nursing, Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
Am J Cardiol 103:1368-73. 2009....
2009 Canadian Hypertension Education Program recommendations: the scientific summary--an annual updateNorman R C Campbell
Department of Medicine, University of Calgary, Calgary, Canada
Can J Cardiol 25:271-7. 2009....
Service barriers of Chinese family caregivers in CanadaDaniel W L Lai
Faculty of Social Work, The University of Calgary, Calgary, Alberta, Canada
J Gerontol Soc Work 51:315-36. 2008..The findings indicate the importance of culturally sensitive support for family caregivers in order to reduce the access barriers...
Cholinergic depletion of the medial septum followed by phase shifting does not impair memory or rest-activity rhythms measured under standard light/dark conditions in ratsLaura A Craig
Canadian Centre for Behavioural Neuroscience, Department of Neuroscience, University of Lethbridge, 4401 University Drive West, Lethbridge, AB, Canada T1K 3M4
Brain Res Bull 79:53-62. 2009....
Increases in glycogenin and glycogenin mRNA accompany glycogen resynthesis in human skeletal muscleJane Shearer
Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
Am J Physiol Endocrinol Metab 289:E508-14. 2005..This may facilitate rapid glycogen resynthesis by providing the glycogenin backbone of proglycogen, the major component of glycogen synthesized in early recovery...
Which older patients are competent to drive? Approaches to office-based assessmentDavid B Hogan
University of Calgary, Alberta
Can Fam Physician 51:362-8. 2005..To review three proposed approaches to office-based assessment of older drivers and to evaluate recommendations made about dementia and driving...
Intrinsic optical signals in the rat optic nerve: role for K(+) uptake via NKCC1 and swelling of astrocytesBrian A MacVicar
Department of Physiology and Biophysics, University of Calgary, Calgary, Alberta, Canada
Glia 37:114-23. 2002..In summary, these results indicated that KCl uptake into astrocytes via an Na-K-2Cl cotransporter during raised [K(+)](o) contributes to the generation of cellular swelling and the intrinsic optical signals...
Peritubular capillary basement membrane reduplication in allografts and native kidney disease: a clinicopathologic study of 278 consecutive renal specimensJ Gough
Department of Surgery, The University of Calgary, Foothills Medical Centre, Calgary, Alberta, Canada
Transplantation 71:1390-3. 2001..Although such an association is of practical and theoretical importance, only one prospective study has tried to confirm it...
Evidence that nitric oxide- and opioid-containing interneurons innervate vessels in the dorsal horn of the spinal cord of ratsD W Zochodne
Department of Clinical Neurosciences and the Neuroscience Research Group, University of Calgary, Calgary, Alberta, Canada, T2N 4N1
J Physiol 532:749-58. 2001..Collateral innervation of blood vessels may explain this property...
Psychosocial components of cardiac recovery and rehabilitation attendanceK M King
EPICORE Centre CQIN, Division of Cardiology, 213 Heritage Medical Research Centre, University of Alberta, Edmonton, Alberta T6G 2S2, Canada
Heart 85:290-4. 2001..To examine the relations between demographic factors, specific psychosocial factors, and cardiac rehabilitation attendance...
The microenvironment of injured and regenerating peripheral nervesD W Zochodne
Department of Clinical Neurosciences, University of Calgary, Room 182A, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada
Muscle Nerve Suppl 9:S33-8. 2000..A better understanding of the injured peripheral nerve microenvironment may allow therapeutic approaches that can enhance regeneration and diminish pain...
Canadian experiences in telehealth: equalizing access to quality careP A Jennett
Health Telematics Unit, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
Telemed J E Health 6:367-71. 2000..Key issues including access, evaluation, implementation, privacy, confidentiality, security, and interoperability are of universal concern to participants. Research that examines the benefits and costs of telehealth is needed...
Hemispheric equivalence and age-related differences in judgments of simultaneity to somatosensory stimuliL N Brown
Department of Psychology, University of Calgary, Calgary, Alberta, Canada
J Clin Exp Neuropsychol 22:587-98. 2000..As well, relative to younger adults, older adults had significantly higher simultaneity thresholds...
Neurohypophysial peptides as retrograde transmitters in the supraoptic nucleus of the ratQ J Pittman
Department of Physiology and Biophysics, University of Calgary, Alberta, Canada
Exp Physiol 85:139S-143S. 2000..We discuss the possible significance of these results in terms of the physiological role of oxytocin in the intact animal and suggest possible avenues for further experimentation...
Giardia vaccinationM E Olson
Departments of Microbiology and Infectious Diseases and Biological Sciences, University of Calgary, Alberta, Canada
Parasitol Today 16:213-7. 2000..Here, Merle Olson, Howard Ceri and Douglas Morck describe studies that led to the development of this vaccine and subsequent efficacy studies. Immunoprophylaxis and immunotherapeutic application of the vaccine are discussed...
A role for voltage-gated potassium channels in the outgrowth of retinal axons in the developing visual systemS McFarlane
University of Calgary, Department of Cell Biology and Anatomy, Calgary, Alberta T2N 4N1, Canada
J Neurosci 20:1020-9. 2000..With the higher doses, <25% of embryos had a normal optic projection. These data suggest that Kv channel activity regulates the guidance of growing axons in the vertebrate brain...
The impact of early onset otitis media on babbling and early language developmentS Rvachew
Speech Language Pathology, Alberta Children s Hospital, Calgary, Canada
J Acoust Soc Am 105:467-75. 1999..In addition, a relationship between canonical babbling ability and expressive vocabulary size was observed at 18 months of age...
Group treatment for substance abuse in schizophreniaJ Addington
Department of Psychiatry, University of Calgary, Alberta
Can J Psychiatry 43:843-5. 1998..The components of the group were support, psychoeducation, and skills training. Attention was also paid to the stage of recovery...
Loss-of-function mutations in a calcium-channel alpha1-subunit gene in Xp11.23 cause incomplete X-linked congenital stationary night blindnessN T Bech-Hansen
Department of Medical Genetics, University of Calgary, Alberta, Canada
Nat Genet 19:264-7. 1998..These findings establish that loss-of-function mutations in CACNA1F cause incomplete CSNB, making this disorder an example of a human channelopathy of the retina...
Dual-track CME: accuracy and outcomeJocelyn M Lockyer
University of Calgary, 3330 Hospital Drive, Canada
Acad Med 77:S61-3. 2002
Development of healthy public policy: feminist analysis of conflict, collaboration and social changeC M Scott
Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
Health Care Women Int 23:530-9. 2002..We suggest that such a shift will be facilitated by strengthening collaborative relations among points of conflict within society and among policy makers and women's organizations...
Rat heart NCX1.1 stoichiometry measured in a transfected cell systemJonathan Lytton
Cardiovascular Research Group, Department of Biochemistry Molecular Biology, University of Calgary, Calgary, AB, Canada T2N 4N1
Ann N Y Acad Sci 976:137-41. 2002....
Nitric oxide and the common coldDavid Proud
Respiratory Research Group and Department of Physiology and Biophysics, University of Calgary, Calgary, Alberta, Canada
Curr Opin Allergy Clin Immunol 5:37-42. 2005..There is growing interest in host innate defence responses that may regulate the severity of viral responses. We will review recent evidence that nitric oxide is an important contributor to the host response during colds...
Varied-mapping conjunction search: evidence for rule-based learningCharles T Scialfa
Department of Psychology, University of Calgary, Calgary AB, T2N 1N4, Canada
Spat Vis 17:543-57. 2004..These studies demonstrate the role of top-down mechanisms in the development of efficient VM search and present several challenges to strength-theoretic views on the mechanisms underlying automaticity...
The impact of two multiple-choice question formats on the problem-solving strategies used by novices and expertsSylvain P Coderre
Department of Medicine, University of Calgary, Health Sciences Centre, 3330 Hospital Drive NW, T2N 4N1, Calgary, Alberta, Canada
BMC Med Educ 4:23. 2004..Secondly, the impact of the alternatives number on psychometrics and problem-solving strategies was examined...
Management of bleeding in patients with advanced cancerJose Pereira
Department of Oncology, University of Calgary, Palliative Care Office, Room 710, South Tower, Foothills Medical Centre, 1403 29th Avenue NW, Calgary, Alberta, T2N 2T9, Canada
Oncologist 9:561-70. 2004..Considerations at the end of life are described...
A Homeric view of kidney evolution: A reprint of H.W. Smith's classic essay with a new introduction. Evolution of the kidney. 1943Peter D Vize
Department of Biological Science, University of Calgary, Alberta, Canada
Anat Rec A Discov Mol Cell Evol Biol 277:344-54. 2004
Biological mediators of acute inflammationJames A Rankin
University of Calgary, Faculty of Nursing, Calgary, Alberta, Canada
AACN Clin Issues 15:3-17. 2004..Rather, the author provides a review of inflammation, an overview of the role of certain biological mediators in inflammation, and a discussion of the implications of certain biological response modifiers in clinical practice...
Control of NKT cell differentiation by tissue-specific microenvironmentsYang Yang
Department of Biochemistry, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
J Immunol 171:5913-20. 2003..The results of the present study suggest that the costimulatory signals of tissue-specific APCs are key factors for NKT cell differentiation, and these signals cannot be replaced by anti-CD28 or anti-CD40 ligand Abs...
Valuing food safety improvements using willingness to payMarjon van der Pol
Health Economics Research Unit, University of Aberdeen, Scotland
Appl Health Econ Health Policy 2:99-107. 2003..Two hundred members of the general public were interviewed and the results show that people are willing to pay extra for food safety. WTP is found to be sensitive to the elicitation format...
Is the target for thalamic deep brain stimulation the same as for thalamotomy?Zelma H T Kiss
Department of Clinical Neurosciences, University of Calgary, Foothills Hospital Calgary Health Region, Calgary, Alberta, Canada
Mov Disord 18:1169-75. 2003..034) to the ideal thalamotomy target. This mismatch may reflect the compromise required between adverse and beneficial effects with chronic stimulation, but it also suggests different mechanisms of effect of DBS and thalamotomy...
Neural substrates of microstimulation-evoked tingling: a chronaxie study in human somatosensory thalamusZelma H T Kiss
Department of Clinical Neuroscience, University of Calgary, 3330 Hospital Dr NW, Calgary, Alberta T2N 4 N1, Canada
Eur J Neurosci 18:728-32. 2003..Therefore, excitations of local axons and/or cell bodies can both contribute to the paraesthesia evoked during intra-operative thalamic mapping...
A national survey on the patterns of treatment of inflammatory bowel disease in CanadaRobert J Hilsden
Department of Medicine, University of Calgary, Calgary, AB, Canada
BMC Gastroenterol 3:10. 2003....
Coumarin therapy in thrombosisGraham Pineo
Foothills Hospital, 601 South Tower, 1403 29 Street, NW, Calgary, Alberta T29 2T9, Canada
Hematol Oncol Clin North Am 17:201-16, viii. 2003..This article reviews the pharmacology of warfarin sodium, the most commonly used oral anticoagulant in North America, and discusses practical aspects of the use of this agent in thrombotic disorder management...
Measuring chemotaxis and chemokinesis: the under-agarose cell migration assayBryan Heit
Immunology Research Group, Department of Physiology and Biophysics, Faculty of Medicine, University of Calgary, Alberta T2N 4N1, Canada
Sci STKE 2003:PL5. 2003..With its relative simplicity, flexibility, and precision, this method is a key tool for the study of cellular chemotactic responses and the signaling processes underlying them...
Neural connectivity only accounts for a small part of neural correlation in auditory cortexJ J Eggermont
Department of Psychology, University of Calgary, Alberta, Canada
Exp Brain Res 110:379-91. 1996..Cross-interval analysis suggests that the correlations in auditory cortex are dynamic and may show random switching between states of stronger and weaker synchronization...
Research Grants
- Enteric Nervous System 2003Keith Sharkey; Fiscal Year: 2003..From this picture there will be gaps - these are the challenges for the future. ..
- Xenbase: a Xenopus Model Organism DatabasePETER VIZE; Fiscal Year: 2009..abstract_text> ..
- Xenbase: a Xenopus Model Organism DatabasePETER VIZE; Fiscal Year: 2007..abstract_text> ..
- Molecular Identification of an Endogenous AdjuvantYan Shi; Fiscal Year: 2006..In all assays, the substance will be tested side by side with uric acid crystals for a direct comparison of their potencies. ..
- 2006 GRC MSK Biology & BioengineeringCYRIL FRANK; Fiscal Year: 2006....
- Bioreactor Expansion and Transplantation of ES Cell Derived Osteoblasts and ChondJohn Matyas; Fiscal Year: 2007....
- The biological relevance of adenosine deamination in immune activationYan Shi; Fiscal Year: 2007..This study deals with a new concept in immune regulation, and will have impact on vaccine development, autoimmune disease intervention and cancer immunotherapy. ..
- PARKINSON'S DISEASE NEUROPROTECTION CLINICAL TRIALS: CLINICAL CENTEROksana Suchowersky; Fiscal Year: 2007..The Movement Disorders Program at the University of Calgary is the only PD clinic in Southern Alberta, serving a population of almost 2 million...
- In vivo studies of cerebral angiogenesis and oxygenationJeffrey Dunn; Fiscal Year: 2007....
- Near infrared/MR system for imaging brain oxygenationJeffrey Dunn; Fiscal Year: 2003..This grant will produce a novel imaging modality which can non-invasively monitor cerebral oxygenation, structure, and blood flow. ..
- Molecular Basis and Treatment of Cardiac ArrhythmiasSUI RONG CHEN; Fiscal Year: 2009....
- GENETIC RISK FACTORS FOR HYPERHOMOCYSTEINEMIAROY GRAVEL; Fiscal Year: 2000..These studies, will determine the importance of genotype in the metabolic causes of hyperhomocysteinemia and risk of cardiovascular disease. (End of Abstract) ..
- Molecular Basis of Cardiac Arrhythmia and Sudden DeathSUI RONG CHEN; Fiscal Year: 2007....
- GENETIC RISK FACTORS FOR HYPERHOMOCYSTEINEMIAROY GRAVEL; Fiscal Year: 2006..In summary, our study will give a biochemical and physiological face to the impact of 122M on enzyme function, development and disease. ..
- Molecular Basis and Treatment of Cardiac ArrhythmiasSUI RONG WAYNE CHEN; Fiscal Year: 2010....
