Cory C Toth

Summary

Country: Canada

Publications

  1. ncbi A patient with bilateral sciatic neuropathies
    Erin K O'Ferrall
    Can J Neurol Sci 34:365-7. 2007
  2. doi Local erythropoietin signaling enhances regeneration in peripheral axons
    C Toth
    Department of Clinical Neurosciences and the Hotchkiss Brain Institute, University of Calgary, Northwest, Calgary, Alberta, Canada
    Neuroscience 154:767-83. 2008
  3. doi Levodopa, methylmalonic acid, and neuropathy in idiopathic Parkinson disease
    Cory Toth
    Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada
    Ann Neurol 68:28-36. 2010
  4. doi Absence of clinical relationship between oxidized low density lipoproteins and diabetic peripheral neuropathy: a case control study
    Alma Rosales-Hernandez
    Department of Clinical Neurosciences, The Hotchkiss Brain Institute, and the University of Calgary, Calgary, AB, Canada
    Lipids Health Dis 13:32. 2014
  5. doi Presence of neuropathic pain may explain poor performances on olfactory testing in diabetes mellitus patients
    Shauna Brady
    Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada
    Chem Senses 38:497-507. 2013
  6. doi An enriched-enrolment, randomized withdrawal, flexible-dose, double-blind, placebo-controlled, parallel assignment efficacy study of nabilone as adjuvant in the treatment of diabetic peripheral neuropathic pain
    Cory Toth
    The Department of Clinical Neurosciences, The Hotchkiss Brain Institute, and the University of Calgary, Calgary, Alberta, Canada
    Pain 153:2073-82. 2012
  7. doi Drug safety evaluation of pregabalin
    Cory Toth
    University of Calgary, Department of Clinical Neurosciences, 3330 Hospital Drive NW, Calgary, Alberta, T2N 4N1, Canada
    Expert Opin Drug Saf 11:487-502. 2012
  8. ncbi Unusual clinical, laboratory, and muscle histopathological findings in a family with myotonic dystrophy type 2
    Cory Toth
    Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta T2N 4N1, Canada
    Muscle Nerve 35:259-64. 2007
  9. pmc Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain
    Cory C Toth
    Department of Clinical Neurosciences and the Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada
    Mol Pain 6:16. 2010
  10. doi Substitution of gabapentin therapy with pregabalin therapy in neuropathic pain due to peripheral neuropathy
    Cory Toth
    Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Pain Med 11:456-65. 2010

Collaborators

Detail Information

Publications48

  1. ncbi A patient with bilateral sciatic neuropathies
    Erin K O'Ferrall
    Can J Neurol Sci 34:365-7. 2007
  2. doi Local erythropoietin signaling enhances regeneration in peripheral axons
    C Toth
    Department of Clinical Neurosciences and the Hotchkiss Brain Institute, University of Calgary, Northwest, Calgary, Alberta, Canada
    Neuroscience 154:767-83. 2008
    ..Exogenous EPO may have a therapeutic role in a large number of peripheral nerve diseases through its impact on regeneration...
  3. doi Levodopa, methylmalonic acid, and neuropathy in idiopathic Parkinson disease
    Cory Toth
    Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada
    Ann Neurol 68:28-36. 2010
    ..We sought to examine the prevalence of PN in a population of IPD patients and a potential relationship to levodopa use and fasting methylmalonic acid (MMA) levels...
  4. doi Absence of clinical relationship between oxidized low density lipoproteins and diabetic peripheral neuropathy: a case control study
    Alma Rosales-Hernandez
    Department of Clinical Neurosciences, The Hotchkiss Brain Institute, and the University of Calgary, Calgary, AB, Canada
    Lipids Health Dis 13:32. 2014
    ..Oxidized low density lipoprotein (oxLDL) is a form of cholesterol that exerts direct toxic effects and contributes to pathogenicity through ligating a receptor called lectin-like receptor (LOX-1)...
  5. doi Presence of neuropathic pain may explain poor performances on olfactory testing in diabetes mellitus patients
    Shauna Brady
    Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada
    Chem Senses 38:497-507. 2013
    ..The presence of neuropathic pain, associated with limited attention and concentration, may explain at least a portion of the olfactory dysfunction witnessed in the diabetic patient population...
  6. doi An enriched-enrolment, randomized withdrawal, flexible-dose, double-blind, placebo-controlled, parallel assignment efficacy study of nabilone as adjuvant in the treatment of diabetic peripheral neuropathic pain
    Cory Toth
    The Department of Clinical Neurosciences, The Hotchkiss Brain Institute, and the University of Calgary, Calgary, Alberta, Canada
    Pain 153:2073-82. 2012
    ..Flexible-dose nabilone 1-4 mg/day was effective in relieving DPN symptoms, improving disturbed sleep, quality of life, and overall patient status. Nabilone was well tolerated and successful as adjuvant in patients with DPN...
  7. doi Drug safety evaluation of pregabalin
    Cory Toth
    University of Calgary, Department of Clinical Neurosciences, 3330 Hospital Drive NW, Calgary, Alberta, T2N 4N1, Canada
    Expert Opin Drug Saf 11:487-502. 2012
    ..Pregabalin is an anticonvulsant with one known mechanism of action which is used most specifically in the management of neuropathic pain...
  8. ncbi Unusual clinical, laboratory, and muscle histopathological findings in a family with myotonic dystrophy type 2
    Cory Toth
    Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta T2N 4N1, Canada
    Muscle Nerve 35:259-64. 2007
    ..When found in the proper clinical context, athleticism and pathological subsarcolemmal vacuoles should not dissuade the clinician from the possible diagnosis of DM2...
  9. pmc Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain
    Cory C Toth
    Department of Clinical Neurosciences and the Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada
    Mol Pain 6:16. 2010
    ..We provided either intranasal or intraperitoneal cannabinoid agonists/antagonists at multiple doses both at the initiation of diabetes as well as after establishment of diabetes and its related NeP state...
  10. doi Substitution of gabapentin therapy with pregabalin therapy in neuropathic pain due to peripheral neuropathy
    Cory Toth
    Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Pain Med 11:456-65. 2010
    ..To determine the utility of substitution of pregabalin (PGB) for gabapentin (GBP) therapy in the relief of neuropathic pain (NeP) in patients with peripheral neuropathy (PN)...
  11. doi The prevalence and impact of chronic pain with neuropathic pain symptoms in the general population
    Cory Toth
    Department of Clinical Neurosciences and the University of Calgary, Calgary, Canada
    Pain Med 10:918-29. 2009
    ..We performed a prevalence estimate of chronic pain with neuropathic pain (NeP) symptoms to determine its frequency and associations with morbidity...
  12. ncbi Dramatic MRI improvement with refractory neurosarcoidosis treated with infliximab
    C Toth
    Department of Clinical Neurosciences, University of Calgary, Calgary, AB, Canada
    Acta Neurol Scand 116:259-62. 2007
    ..Neurosarcoidosis is often a devastating, refractory condition without definite pharmacotherapies beyond corticosteroids...
  13. ncbi Receptor for advanced glycation end products (RAGEs) and experimental diabetic neuropathy
    Cory Toth
    University of Calgary, Department of Clinical Neurosciences, Room 155, 3330 Hospital Dr, N W, Calgary, Alberta T2N 4N1, Canada
    Diabetes 57:1002-17. 2008
    ..We studied experimental diabetic neuropathy and its relationship with RAGE expression using streptozotocin-induced diabetic mice including a RAGE(-/-) cohort exposed to long-term diabetes compared with littermates without diabetes...
  14. pmc Hemisensory syndrome is associated with a low diagnostic yield and a nearly uniform benign prognosis
    C Toth
    Division of Neurology, Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    J Neurol Neurosurg Psychiatry 74:1113-6. 2003
    ..To describe the diagnostic yield and prognosis for patients with hemisensory syndrome...
  15. doi The epidemiology of injuries to the nervous system resulting from sport and recreation
    Cory Toth
    Department of Clinical Neurosciences, University of Calgary, Heritage Medical Research Bldg, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada
    Neurol Clin 26:1-31; vii. 2008
    ..The association between particular forms of injuries and the sports in which they are likely to be incurred are also investigated. Further assessment of preventative measures is provided when possible...
  16. doi Peripheral nerve injuries attributable to sport and recreation
    Cory Toth
    Department of Clinical Neurosciences, University of Calgary, Heritage Medical Research Building, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1
    Neurol Clin 26:89-113; viii-ix. 2008
    ..This article should be of assistance for the neurologist, neurosurgeon, orthopedic surgeon, physiatrist, sports medicine doctor, and general physician in contact with athletes at risk for neurologic injuries...
  17. ncbi RAGE, diabetes, and the nervous system
    Cory Toth
    Department of Clinical Neurosciences and the Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada
    Curr Mol Med 7:766-76. 2007
    ..This review will discuss current knowledge of diabetes- and RAGE-mediated neurodegeneration, involving the distal-most level of epidermal nerve fibers in skin, major peripheral nerve trunks, dorsal root ganglia, spinal cord, and brain...
  18. doi Poor tolerability of high dose ascorbic acid in a population of genetically confirmed adult Charcot-Marie-Tooth 1A patients
    C Toth
    Department of Clinical Neurosciences, University of Calgary, Calgary, AB, Canada
    Acta Neurol Scand 120:134-8. 2009
    ..Preclinical studies have suggested that ascorbic acid (AA) treatment in a mouse model of Charcot-Marie-Tooth type 1A (CMT1A) improves motor function and prolongs lifespan...
  19. ncbi Acetylcholine receptor antibodies in myasthenia gravis are associated with greater risk of diabetes and thyroid disease
    C Toth
    Department of Clinical Neurosciences, University of Calgary and the Calgary Health Region, Calgary, Alberta, Canada
    Acta Neurol Scand 114:124-32. 2006
    ..Along with features of MG, the presence of the AChRAb may relate to the existence of other immune-mediated diseases. We sought to determine the association of SPMG with other potential autoimmune diseases...
  20. ncbi Diabetes, leukoencephalopathy and rage
    Cory Toth
    Department of Clinical Neurosciences and the Neuroscience Research Group, University of Calgary, Alberta, Canada
    Neurobiol Dis 23:445-61. 2006
    ..Our findings identify a robust and novel model of cerebral, particularly white matter, involvement with diabetes associated with abnormal RAGE signaling...
  21. ncbi Validation of a weight-based nomogram for the use of intravenous heparin in transient ischemic attack or stroke
    Cory Toth
    Division of Neurology, Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Stroke 33:670-4. 2002
    ..We attempted to validate the use of a weight-based nomogram for heparin-adjusted therapy during hospital admission of patients with TIA or stroke...
  22. ncbi Representational bias does not affect bisection of lines with a pictorially or semantically defined top by patients with left hemispatial neglect
    Cory Toth
    Division of Neurology, Department of Medicine, University of Saskatchewan, Saskatoon, Canada
    Brain Cogn 50:167-77. 2002
    ....
  23. ncbi Medications and substances as a cause of headache: a systematic review of the literature
    Cory Toth
    Department of Clinical Neurosciences, University of Calgary, Alberta, Canada
    Clin Neuropharmacol 26:122-36. 2003
    ..Suggestions for improved identification of this phenomenon and its avoidance are provided. More scientific evaluation of substances and their possible association with headache is required with almost all substances indicated herein...
  24. ncbi The use of a bolus of intravenous heparin while initiating heparin therapy in anticoagulation following transient ischemic attack or stroke does not lead to increased morbidity or mortality
    Cory Toth
    Department of Medicine, University of Saskatchewan, Saskatoon, Canada
    Blood Coagul Fibrinolysis 14:463-8. 2003
    ..The use of an intravenous heparin bolus during initiation of anticoagulation for TIA or stroke does not appear to be associated with greater risks and can achieve a minimum therapeutic range faster than therapy without heparin bolus...
  25. doi A prospective identification of neuropathic pain in specific chronic polyneuropathy syndromes and response to pharmacological therapy
    Cory Toth
    Department of Clinical Neurosciences, University of Calgary, HMRB Room 155, 3330 Hospital Drive NW, Calgary, Alta T2N4N1, Canada
    Pain 138:657-66. 2008
    ..Future studies assessing longer duration of follow-up and quality of life changes with the use of various pharmacotherapies for management of NeP due to PN will be important...
  26. ncbi Mononeuropathy multiplex in association with livedoid vasculitis
    Cory Toth
    Department of Neurological Sciences, Room 165, Heritage Medical Research Building, University of Calgary, 3330 Hospital Dr NW, Calgary, Alberta T2N 4N1, Canada
    Muscle Nerve 28:634-9. 2003
    ..We propose that peripheral nervous system involvement arises from multifocal areas of ischemia due to fibrin and thrombin deposition within both the wall and lumen of vasa nervorum...
  27. ncbi Anomalies of asymmetry of clinical signs in parkinsonism
    Cory Toth
    Division of Neurology, Department of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Mov Disord 19:151-7. 2004
    ....
  28. ncbi Central nervous system injuries in sport and recreation: a systematic review
    Cory Toth
    Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Sports Med 35:685-715. 2005
    ....
  29. ncbi Peripheral nervous system injuries in sport and recreation: a systematic review
    Cory Toth
    Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Sports Med 35:717-38. 2005
    ..This review should be of assistance for the neurologist, neurosurgeon, orthopaedic surgeon, physiatrist, sports medicine doctor, athletic trainer and general physician in contact with athletes possessing neurological injuries...
  30. ncbi Remote neurotrophic support of epidermal nerve fibres in experimental diabetes
    C Toth
    Department of Clinical Neurosciences and the Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada
    Diabetologia 49:1081-8. 2006
    ..In diabetic neuropathy, distal loss of axons is an important clinical and pathological feature. We hypothesised that insulin and IGF-1 delivered intrathecally could support the most distal epidermal nerve fibres...
  31. doi Neuropathy as a potential complication of levodopa use in Parkinson's disease
    Cory Toth
    Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Mov Disord 23:1850-9. 2008
    ..PN in PD patients may be associated with iatrogenic Cbl metabolic abnormalities. Alternatively PN may be a peripheral nervous system manifestation of PD...
  32. pmc Comparison of central versus peripheral delivery of pregabalin in neuropathic pain states
    Jose A Martinez
    Department of Clinical Neurosciences and the University of Calgary, Calgary, AB, Canada
    Mol Pain 8:3. 2012
    ..Direct targeting of the central nervous system may be beneficial for the avoidance of systemic side effects...
  33. doi An open-label comparison of nabilone and gabapentin as adjuvant therapy or monotherapy in the management of neuropathic pain in patients with peripheral neuropathy
    Jennifer A Bestard
    Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Pain Pract 11:353-68. 2011
    ..We advocate for head-to-head randomized, double-blind studies for current therapies for NeP in order to determine potential advantages beneficial in this patient population...
  34. doi Locally synthesized calcitonin gene-related Peptide has a critical role in peripheral nerve regeneration
    Cory C Toth
    Departments of Clinical Neurosciences and the Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada
    J Neuropathol Exp Neurol 68:326-37. 2009
    ..These findings indicate that robust localized intra-axonal translation of the CGRP neuropeptide during regeneration signals Schwann cell proliferation, behavior that is critical for partnering during adult peripheral nerve regrowth...
  35. ncbi Does diabetes mellitus target motor neurons?
    Noor Ramji
    University of Calgary, Department of Clinical Neurosciences, Room 168, 3330 Hospital Drive, N W, Calgary, Alberta, Canada T2N 4N1
    Neurobiol Dis 26:301-11. 2007
    ..Overall these findings indicate that although motor neurons are resistant to irretrievable dropout, they are targeted nonetheless by diabetes and gradually withdraw their terminals from distal innervation...
  36. pmc Association of metformin, elevated homocysteine, and methylmalonic acid levels and clinically worsened diabetic peripheral neuropathy
    Daryl J Wile
    Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    Diabetes Care 33:156-61. 2010
    ..We hypothesized that metformin exposure would be associated with lower Cbl levels, elevated Hcy and MMA levels, and more severe peripheral neuropathy...
  37. ncbi Intranasal treatment of neurodegenerative diseases and stroke
    Diana Gómez
    Department of Clinical Neurosciences and the Hotchkiss Brain Institute, The University of Calgary, Calgary, AB, Canada
    Front Biosci (Schol Ed) 4:74-89. 2012
    ..We will examine the evidence behind the use of intranasal delivery in chronic neurodegenerative conditions such as Alzheimer's Disease and diabetes-mediated cerebral degeneration, as well as in acute conditions such as stroke...
  38. pmc Ndel1 promotes axon regeneration via intermediate filaments
    Cory Toth
    Department of Clinical Neurosciences, University of Calgary, Hotchkiss Brain Institute, Calgary, Canada
    PLoS ONE 3:e2014. 2008
    ..Thus, Ndel1 promotes axonal regeneration; activating this endogenous repair mechanism may enhance neuroregeneration during acute and chronic axonal degeneration...
  39. pmc Intranasal insulin ameliorates experimental diabetic neuropathy
    George Francis
    Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Diabetes 58:934-45. 2009
    ....
  40. ncbi Persistent cerebrospinal fluid abnormalities in the syndrome of headache, neurological deficit, and cerebrospinal fluid lymphocytosis despite resolution of clinical symptomatology
    Cory C Toth
    Division of Neurology, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Headache 42:1038-43. 2002
  41. ncbi Recurrence of migraine with aura due to tacrolimus therapy in a liver transplant recipient successfully treated with sirolimus substitution
    Cory C Toth
    University of Calgary, Neurosciences, Calgary, Alberta, Canada
    Headache 45:245-6. 2005
    ....
  42. doi Intranasal insulin prevents cognitive decline, cerebral atrophy and white matter changes in murine type I diabetic encephalopathy
    George J Francis
    Department of Clinical Neurosciences and the Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada
    Brain 131:3311-34. 2008
    ..This therapy and delivery mode, available in humans, may be of clinical utility for the prevention of pathological changes in the diabetic human brain...
  43. ncbi Pseudomigraine with lymphocytic pleocytosis: a calcium channelopathy? Clinical description of 10 cases and genetic analysis of the familial hemiplegic migraine gene CACNA1A
    Kristine M Chapman
    Division of Neurology, University of British Columbia, Vancouver, BC, Canada
    Headache 43:892-5. 2003
    ..To report the clinical findings of 10 patients diagnosed with pseudomigraine with lymphocytic pleocytosis and the results of mutational analysis of the CACNA1A gene in 8 of these patients...
  44. ncbi Primary CNS lymphoma as a cause of Korsakoff syndrome
    Cory Toth
    Division of Neurology, Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Surg Neurol 57:41-5. 2002
    ..The most common etiology of Korsakoff syndrome is thiamine deficiency secondary to alcoholism. There are limited case reports of structural lesions causing Korsakoff syndrome...
  45. ncbi Other autonomic neuropathies
    Cory Toth
    Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Semin Neurol 23:373-80. 2003
    ..This article reviews the clinical presentation, diagnosis, pathogenesis, and management of the acquired forms of autonomic neuropathy...
  46. ncbi Anti-MuSK myasthenia gravis presenting with Epstein-Barr virus-associated mononucleosis and immune-mediated diabetes mellitus
    Arunee Bhibhatbhan
    Department of Clinical Neurosciences, University of Calgary, 3330 Hospital Drive NW, HMRB Room 155, Calgary, Alberta T2N 4N1, Canada
    Muscle Nerve 36:264-6. 2007
    ..The simultaneous onset of these two autoimmune diseases preceded by a systemic viral illness supports a causal relationship between MuSK antibodies and myasthenia gravis and suggests the possibility of a viral trigger in some cases...
  47. ncbi Autonomic disorders and the eye
    Cory Toth
    J Neuroophthalmol 25:1-4. 2005
  48. doi Sports neurology. Preface
    Cory Toth
    Neurol Clin 26:xv-xvi. 2008