Research Topics
| Edward ChowSummaryAffiliation: Toronto-Sunnybrook Regional Cancer Centre Country: Canada Publications
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Detail Information
Publications
Cutaneous and subcutaneous Ewing's sarcoma: an indolent diseaseE Chow
Department of Radiation Oncology, St Jude Children s Research Hospital, Memphis, TN, USA
Int J Radiat Oncol Biol Phys 46:433-8. 2000..A retrospective review of patients with cutaneous or subcutaneous ES was conducted to analyze outcome and patterns of failure...
Does psychosocial intervention improve survival in cancer? A meta-analysisEdward Chow
Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Ontario, Canada
Palliat Med 18:25-31. 2004..A systematic review of randomized trials that have examined the effectiveness of psychosocial intervention in cancer patients in terms of survival prolongation was conducted...
Radiotherapeutic approaches to metastatic diseaseEdward Chow
Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, 2075 Bayview Avenue, ON M4 N 3M5, Toronto, Canada
World J Urol 21:229-42. 2003..This article focuses on the management of bone pain and its complications (pathological fractures and spinal cord compression) with radiation treatment...
A predictive model for survival in metastatic cancer patients attending an outpatient palliative radiotherapy clinicEdward Chow
Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Canada
Int J Radiat Oncol Biol Phys 53:1291-302. 2002..To develop a predictive model for survival from the time of presentation in an outpatient palliative radiotherapy clinic...
Patients with advanced cancer: a survey of the understanding of their illness and expectations from palliative radiotherapy for symptomatic metastasesE Chow
Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Canada
Clin Oncol (R Coll Radiol) 13:204-8. 2001..We plan to provide educational pamphlets for use in referring doctors' surgeries and clinics in order to inform patients of the nature, rationale and anticipated benefits and side-effects of palliative radiotherapy...
How accurate are physicians' clinical predictions of survival and the available prognostic tools in estimating survival times in terminally ill cancer patients? A systematic reviewE Chow
Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Canada
Clin Oncol (R Coll Radiol) 13:209-18. 2001..However, there is weak evidence to support that clinicians' estimates alone could be specifically employed for survival prediction...
Referring physicians' satisfaction with the rapid response radiotherapy programme. Survey results at the Toronto-Sunnybrook Regional Cancer CentreE Chow
Division of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Canada
Support Care Cancer 8:405-9. 2000..As a result of this survey we corrected some of our deficiencies. We plan to survey our patients' needs and satisfaction to further improve our programme, since the patients are the ultimate consumers of the service...
Comparing baseline symptom severity and demographics over two time periods in an outpatient palliative radiotherapy clinicLuluel Khan
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Support Care Cancer 20:549-55. 2012..The secondary objective was to assess any changes in the baseline demographics of these patients...
Symptom clusters in patients with advanced cancer: a reanalysis comparing different statistical methodsEmily Chen
Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
J Pain Symptom Manage 44:23-32. 2012..The clinical relevance of symptom cluster research remains questionable if inconsistencies, partially attributable to the varying statistical analyses used, exist...
Percutaneous vertebroplasty in patients with intractable pain from osteoporotic or metastatic fractures: A prospective study using quality-of-life assessmentGordon Cheung
Bone Metastases Clinic, Toronto Sunnybrook Regional Cancer Centre, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, ON
Can Assoc Radiol J 57:13-21. 2006..We prospectively evaluate the efficacy of PVP in the relief of pain and improvement in quality of life of patients with intractable pain from osteoporotic and metastatic fractures...
Determining the incidence of pain flare following palliative radiotherapy for symptomatic bone metastases: results from three canadian cancer centersAmanda Hird
Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
Int J Radiat Oncol Biol Phys 75:193-7. 2009..To determine the incidence of pain flare following radiotherapy (RT) for painful bone metastases...
Projected referral to other healthcare services in an outpatient palliative radiotherapy clinicJanet Nguyen
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, University of Toronto, Toronto, ON, M4N 3M5, Canada
Expert Rev Pharmacoecon Outcomes Res 12:237-43. 2012..To investigate the projected referral to other healthcare services in an outpatient palliative radiotherapy clinic...
Fatigue in advanced cancer patients attending an outpatient palliative radiotherapy clinic as screened by the Edmonton Symptom Assessment SystemLiang Zeng
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Support Care Cancer 20:1037-42. 2012..The purpose of this study was to report the presence, severity, and correlating factors of fatigue in advanced cancer patients attending an outpatient palliative radiotherapy clinic...
Symptom clusters in patients with bone metastases--a reanalysis comparing different statistical methodsEmily Chen
Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Support Care Cancer 20:2811-20. 2012....
EORTC QLQ-C15-PAL quality of life scores in patients with advanced cancer referred for palliative radiotherapyAmanda Caissie
Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Support Care Cancer 20:841-8. 2012....
Comparison of pain response and functional interference outcomes between spinal and non-spinal bone metastases treated with palliative radiotherapyLiang Zeng
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada
Support Care Cancer 20:633-9. 2012....
Physician expectations of treatment outcomes for patients with brain metastases referred for whole brain radiotherapyElizabeth A Barnes
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 76:187-92. 2010..The secondary objectives were to determine the factors influencing the expectations and to examine the accuracy of the physician-estimated patient survival...
Validation of a predictive model for survival in metastatic cancer patients attending an outpatient palliative radiotherapy clinicEdward Chow
Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 73:280-7. 2009..To validate a predictive model for survival of patients attending a palliative radiotherapy clinic...
Retrospective assessment of cancer pain management in an outpatient palliative radiotherapy clinic using the Pain Management IndexGunita Mitera
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada M4N 3M5
J Pain Symptom Manage 39:259-67. 2010....
Prophylaxis of radiotherapy-induced nausea and vomiting in the palliative treatment of bone metastasesKristopher Dennis
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Support Care Cancer 20:1673-8. 2012..To document the incidence and timing of radiotherapy-induced nausea and vomiting (RINV) in the treatment of bone metastases among patients receiving prophylaxis with a 5-HT(3) receptor antagonist...
FACT-Br for assessment of quality of life in patients receiving treatment for brain metastases: a literature reviewKaren Lien
Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada
Expert Rev Pharmacoecon Outcomes Res 11:701-8. 2011..We aim to provide a comprehensive review to examine the use of the FACT-Br as a QoL assessment for patients with brain metastases...
International patterns of practice in palliative radiotherapy for painful bone metastases: evidence-based practice?Alysa Fairchild
Department of Radiation Oncology, Cross Cancer Institute, Edmonton, AB, Canada
Int J Radiat Oncol Biol Phys 75:1501-10. 2009..However, according to previous surveys, SF schedules remain underused. The objectives of this study were to determine the current patterns of practice internationally and to investigate the factors influencing this practice...
Symptoms and quality of life in cancer patients with brain metastases following palliative radiotherapyJennifer Wong
Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Canada
Int J Radiat Oncol Biol Phys 75:1125-31. 2009..To examine prospectively patient self-rated symptoms and quality of life (QOL) indicators in patients with brain metastases following whole brain radiotherapy (WBRT)...
Has pain management in cancer patients with bone metastases improved? A seven-year review at an outpatient palliative radiotherapy clinicAndrea M Kirou-Mauro
Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
J Pain Symptom Manage 37:77-84. 2009....
Quality of life in patients with brain metastases treated with a palliative course of whole-brain radiotherapyMegan Doyle
Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada
J Palliat Med 10:367-74. 2007..The secondary objective was to assess the level of agreement between patient and proxy quality of life scores...
Elderly patients with painful bone metastases should be offered palliative radiotherapySarah Campos
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 76:1500-6. 2010..To investigate the efficacy of palliative radiotherapy (RT) in relieving metastatic bone pain in elderly patients...
Correlation of computed tomography imaging features with pain response in patients with spine metastases after radiation therapyGunita Mitera
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada M4N 3M5
Int J Radiat Oncol Biol Phys 81:827-30. 2011..To correlate computed tomography (CT) imaging features of spinal metastases with pain relief after radiotherapy (RT)...
Dexamethasone for the prophylaxis of radiation-induced pain flare after palliative radiotherapy for bone metastases: a pilot studyEdward Chow
Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Center, University of Toronto, Toronto, Canada
Support Care Cancer 15:643-7. 2007..To investigate the efficacy of dexamethasone as a prophylactic adjuvant analgesic to decrease pain flare and to assess its safety and tolerance of dexamethasone...
Patients' and health care professionals' evaluation of health-related quality of life issues in bone metastasesKristin Harris
Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
Eur J Cancer 45:2510-8. 2009..This information has been an important component in the development of a health-related quality of life questionnaire for patients with bone metastases (EORTC QLQ-BM 22)...
Quality of life after palliative radiation therapy for patients with painful bone metastases: results of an international study validating the EORTC QLQ-BM22Liang Zeng
Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
Int J Radiat Oncol Biol Phys 84:e337-42. 2012..The purpose of our study was to compare bone metastasis-specific QOL scores among patients who responded differently to palliative RT...
Symptom clusters in patients with advanced cancer: sub-analysis of patients reporting exclusively non-zero ESAS scoresEmily Chen
Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Palliat Med 26:826-33. 2012..Varying statistical methods may also contribute to inconsistencies of cluster results...
Do elderly patients with metastatic cancer have worse quality of life scores?Kaitlin Koo
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Support Care Cancer 20:2121-7. 2012..The purpose of this study is to compare self-reported quality of life (QOL) scores in old and young patients with metastatic cancer using the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C15-PAL questionnaire...
International patterns of practice in the management of radiation therapy-induced nausea and vomitingKristopher Dennis
Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Int J Radiat Oncol Biol Phys 84:e49-60. 2012..To investigate international patterns of practice in the management of radiation therapy-induced nausea and vomiting (RINV)...
Subgroups of advanced cancer patients clustered by their symptom profiles: quality-of-life outcomesAmna Husain
Temmy Latner Centre for Palliative Care, Mount Sinai Hospital, Toronto, Ontario, Canada
J Palliat Med 14:1246-53. 2011..This study clustered patients by their symptom profiles to identify subgroups that may be at higher risk for poor quality of life (QOL) and that may, therefore, benefit most from targeted interventions...
Involvement of family physicians in the care of cancer patients seen in the palliative Rapid Response Radiotherapy ProgramElizabeth A Barnes
Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, 2075 Bayview Ave, Toronto, Ontario, Canada, M4N 3M5
J Clin Oncol 25:5758-62. 2007..Secondary objectives were to identify factors predicting for perceived FP involvement in patient cancer care...
Predictive model for survival in patients with advanced cancerEdward Chow
Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
J Clin Oncol 26:5863-9. 2008..To derive and validate a simple predictive model for survival of patients with metastatic cancer attending a palliative radiotherapy clinic...
Rare bone metastases of the olecranonShaelyn Culleton
Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
J Palliat Med 11:1088-91. 2008..The incidence of olecranon metastasis is extremely rare in all cancers and so far only two cases have been reported in literature. We report the third case of an olecranon metastasis in a patient with renal cell carcinoma...
Continued success of the rapid response radiotherapy program: a review of 2004-2008Eric de Sa
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada
Support Care Cancer 17:757-62. 2009..To update the clinical activity of the Rapid Response Radiotherapy Program (RRRP)...
Rapid improvement in pain and functional level in a patient with metastatic renal cell carcinoma: a case report and review of the literatureAmanda E Hird
Rapid Response Radiotherapy Program, Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
J Palliat Med 11:1156-61. 2008..Concurrently, quality of life and performance status improved dramatically. Although we are unsure of the exact mechanism for such rapid improvement in metastatic bone lesions, the swiftness this improvement deserves reporting...
Quality of life in patients with brain metastases using the EORTC QLQ-BN20+2 and QLQ-C15-PALAmanda Caissie
Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Int J Radiat Oncol Biol Phys 83:1238-45. 2012....
Update of the international consensus on palliative radiotherapy endpoints for future clinical trials in bone metastasesEdward Chow
Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 82:1730-7. 2012....
The EORTC QLQ-BN20 for assessment of quality of life in patients receiving treatment or prophylaxis for brain metastases: a literature reviewAndrew Leung
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Expert Rev Pharmacoecon Outcomes Res 11:693-700. 2011..The European Organization for Research and Treatment of Cancer (EORTC) QLQ-BN20 is a QoL assessment specific to brain neoplasms. We aim to provide a review of the current use of the EORTC QLQ-BN20 for patients with brain metastases...
Is response to radiotherapy in patients related to the severity of pretreatment pain?Andrea Kirou-Mauro
Department of Radiation Oncology, Odette Cancer Center, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 71:1208-12. 2008..The primary objective of this study was to determine whether there is a relationship between the severity of pretreatment pain and response to palliative radiotherapy (RT) for painful bone metastases...
The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire for patients with bone metastases: the EORTC QLQ-BM22Edward Chow
Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N3M5, Canada
Eur J Cancer 45:1146-52. 2009..The aim of this study was to develop a bone metastases module to supplement the European Organisation for Research and Treatment of Cancer Core Questionnaire (EORTC QLQ-C30) or the EORTC QLQ-C15-PAL for patients with bone metastases...
Communication with referring physicians in a palliative radiotherapy clinicElizabeth A Barnes
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, M4 N 3M5, Canada
Support Care Cancer 12:669-73. 2004..The purpose of this study was to assess how useful referring physicians perceive this interim report and whether this report needs to be modified to meet their information needs...
Recursive partitioning analysis of prognostic factors for survival in patients with advanced cancerEdward Chow
Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 73:1169-76. 2009..To construct a predictive model for survival of patients referred to the Rapid Response Radiotherapy Program using recursive partitioning (RP)...
Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastasesMay N Tsao
Department ofRadiationOncology, OdetteCancerCentre, Toronto, Canada
Cochrane Database Syst Rev 4:CD003869. 2012..Brain radiotherapy is used to treat cancer participants who have brain metastases from various primary malignancies.This is an update to the original review published in Issue 3, 2006...
A literature review of symptom clusters in patients with breast cancerJanet Nguyen
Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Expert Rev Pharmacoecon Outcomes Res 11:533-9. 2011....
Prospective assessment of patient-rated symptoms following whole brain radiotherapy for brain metastasesEdward Chow
Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Center, University of Toronto, Toronto, Ontario, Canada
J Pain Symptom Manage 30:18-23. 2005..0 to 1.8; drowsiness 1.2 to 1.8; and appetite 2.2 to 2.4. The data demonstrate that certain parameters of quality of life worsen after whole brain radiotherapy...
Computed tomography (CT) evaluation of breast cancer patients with osteolytic bone metastases undergoing palliative radiotherapy--a feasibility studyEdward Chow
Rapid Response Radiotherapy Program and Bone Metastases Site Group, Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
Radiother Oncol 70:291-4. 2004..The median % density change following single 8Gy, 20Gy/5#, 30Gy/10# were: 128 (range 98-255), 141 (79-342), and 145 (65-235), respectively. It is feasible to evaluate remineralization of osteolytic lesions with palliative radiotherapy...
A multicenter assessment of the adequacy of cancer pain treatment using the pain management indexGunita Mitera
Department of Radiation Therapy, Odette Cancer Center, University of Toronto, Toronto, Ontario, Canada
J Palliat Med 13:589-93. 2010....
The palliative performance scale: examining its inter-rater reliability in an outpatient palliative radiation oncology clinicSarah Campos
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Center, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada
Support Care Cancer 17:685-90. 2009..Currently, it is being used to measure palliative patient performance status in a variety of settings. Despite its widespread use, only one study has examined the inter-rater reliability of the PPS...
Exploration of symptoms clusters within cancer patients with brain metastases using the Spitzer Quality of Life IndexAmanda Hird
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada
Support Care Cancer 18:335-42. 2010..The objective of this study was to explore the presence of symptom clusters in patients with brain metastases treated with whole brain radiotherapy (WBRT)...
Accuracy of survival prediction by palliative radiation oncologistsEdward Chow
Division of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
Int J Radiat Oncol Biol Phys 61:870-3. 2005..To examine the accuracy of survival prediction by palliative radiation oncologists...
Comparing prognostic factors in patients with spinal metastases: a literature reviewMarko Popovic
Department of Radiation Oncology, Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Expert Rev Pharmacoecon Outcomes Res 12:345-56. 2012..For future studies, the authors encourage the development of models capable of inclusion of all patients with spinal metastases...
International field testing of the reliability and validity of the EORTC QLQ-BM22 module to assess health-related quality of life in patients with bone metastasesEdward Chow
Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
Cancer 118:1457-65. 2012....
Evaluating correlation and interrater reliability for four performance scales in the palliative care settingJeff Myers
Palliative Care Consult Team, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5, Canada
J Pain Symptom Manage 39:250-8. 2010..In addition, given that low levels of exact rater agreement could have substantial clinical implications for patients, we suggest that this parameter be considered in the design of future comparative studies...
Treatment of bone metastases with palliative radiotherapy: patients' treatment preferencesEwa Szumacher
Rapid Response Radiotherapy Program, Bone Metastases Site Group, Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 61:1473-81. 2005..800 cGy in one fraction) for painful bone metastases...
Functional interference clusters in cancer patients with bone metastases: a secondary analysis of RTOG 9714Edward Chow
Department of Radiation Oncology, Odette Cancer Centre, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 76:1507-11. 2010..To explore the relationships (clusters) among the functional interference items in the Brief Pain Inventory (BPI) in patients with bone metastases...
The role of plain radiographs in management of bone metastasesNadia Salvo
Department of Radiation Oncology, Sunnybrook Odette Cancer Centre, Toronto, Ontario, Canada
J Palliat Med 12:195-8. 2009..However, plain x-rays can also lead to rare false-positive results. We present a case with a false-positive result in a patient with lung cancer...
Mild, moderate, or severe pain categorized by patients with cancer with bone metastasesEdward Chow
Rapid Response Therapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Canada
J Palliat Med 9:850-4. 2006..To examine how patients categorize their pain with the two commonly employed scales...
Would larger radiation fields lead to a faster onset of pain relief in the palliation of bone metastases?Edward Chow
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada
Int J Radiat Oncol Biol Phys 74:1563-6. 2009..The primary objective of this study is to examine whether there is a relationship between the areas of radiation treatment and onset of pain relief...
Prophylaxis of radiation-induced nausea and vomiting using 5-hydroxytryptamine-3 serotonin receptor antagonists: a systematic review of randomized trialsNadia Salvo
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
Int J Radiat Oncol Biol Phys 82:408-17. 2012..To systematically review the effectiveness and safety of 5-hydroxytryptamine-3 receptor antagonists (5-HT3 RAs) compared with other antiemetic medication or placebo for prophylaxis of radiation-induced nausea and vomiting...
Self-reported rates of sleep disturbance in patients with symptomatic bone metastases attending an outpatient radiotherapy clinicLuluel Khan
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
J Palliat Med 14:708-14. 2011..To examine the reported rates and predictive factors for sleep disturbance in patients with bone metastases...
Edmonton symptom assessment scale as a prognosticative indicator in patients with advanced cancerLiang Zeng
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Canada
J Palliat Med 14:337-42. 2011..Few studies incorporate patient self-assessment scales in prognostic models of survival prediction. The Edmonton Symptom Assessment Scale (ESAS) is commonly used as a symptom screening tool in cancer patients...
Survey on use of palliative radiotherapy in hospice careStephen Lutz
Department of Radiation Oncology, Blanchard Valley Regional Cancer Center, Findlay, OH 45840, USA
J Clin Oncol 22:3581-6. 2004....
Comparison of the EORTC QLQ-BM22 and the FACT-BP for assessment of quality of life in cancer patients with bone metastasesMarko Popovic
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, M4N 3M5, ON, Canada
Expert Rev Pharmacoecon Outcomes Res 12:213-9. 2012..The purpose of this study was to compare the development and characteristics of these two tools, as well as their current use in palliative research...
Comparison of the EORTC QLQ-C15-PAL and the FACIT-Pal for assessment of quality of life in patients with advanced cancerKaren Lien
Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Expert Rev Pharmacoecon Outcomes Res 11:541-7. 2011..Future studies should directly compare these two tools and validate their use through a number of administration modes...
Successful salvage using percutaneous vertebroplasty in cancer patients with painful spinal metastases or osteoporotic compression fracturesEdward Chow
Bone Metastases Clinic, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Ontario, Canada M4N 3M5
Radiother Oncol 70:265-7. 2004..Percutaneous vertebroplasty significantly improved pain, mobility and quality of life in cancer patients with bone metastases who failed radiation or with osteoporotic compression fractures. The serious complication is relatively rare...
Multidisciplinary radiation oncology palliative care rounds as a continuing educational activity implementing the rapid response radiotherapy program at the toronto sunnybrook regional cancer centreEwa Szumacher
Department of Radiation Oncology, University of Toronto, Ontario, Canada
J Cancer Educ 18:86-90. 2003....
Immediate pain relief and improved structural stability after percutaneous vertebroplasty for a severely destructive vertebral compression fractureJennifer Wong
Rapid Response Radiotherapy Program, Odette Cancer Centre, Toronto, Ontario, Canada
J Palliat Med 12:97-100. 2009..Percutaneous vertebroplasty provided immediate pain relief and restored structural stability of the diseased vertebra...
Symptom clusters in patients with cancer with metastatic bone painStephanie Hadi
Department of Radiation Oncology, Odette Cancer Centre, Toronto, Ontario, Canada
J Palliat Med 11:591-600. 2008..Secondary objectives were to determine whether symptom clusters change with palliative radiotherapy (RT) and to compare the difference between responders and nonresponders to radiation...
Radiotherapeutic management of brain metastases: a systematic review and meta-analysisMay N Tsao
Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, 2075 Bayview Avenue, Toronto, Ont, Canada M4N 3M5
Cancer Treat Rev 31:256-73. 2005..The management of brain metastases is a significant health care problem. An estimated 20-40% of cancer patients will develop metastatic cancer to the brain during the course of their illness...
Patient expectation of the partial response and response shift in pain scoreEdward Chow
Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Canada
Support Cancer Ther 4:110-8. 2007..This might become the definition of partial response in future trials. Response shift was observed in this group of patients but in opposing directions and without affecting the overall outcome...
A phase II trial of palliative radiotherapy for metastatic renal cell carcinomaJustin Lee
Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
Cancer 104:1894-900. 2005..Improvements in global pain and QOL appear to be limited by the effects of progressive systemic disease...
What should be the optimal cut points for mild, moderate, and severe pain?Kathy K Li
Department of Radiation Oncology, Odette Cancer Centre, Toronto, Ontario, Canada
J Palliat Med 10:1338-46. 2007..Thus, the purpose of the current study was to identify optimal cut points (CP) of the three pain severity categories for worst, average, and current pain...
Palliative radiotherapy trials for bone metastases: a systematic reviewEdward Chow
Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Ontario, Canada
J Clin Oncol 25:1423-36. 2007..The objective is to update previous meta-analyses with a systematic review of randomized palliative radiotherapy (RT) trials comparing single fractions (SFs) versus multiple fractions (MFs)...
Clinical benefit of reirradiation: a case reportCandi J Flynn
Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada
J Palliat Med 11:112-6. 2008
Pain flare following external beam radiotherapy and meaningful change in pain scores in the treatment of bone metastasesEdward Chow
Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, Ont M4N 3M5, Canada
Radiother Oncol 75:64-9. 2005..To examine the incidence of pain flare following external beam radiotherapy and to determine what constitutes a meaningful change in pain scores in the treatment of bone metastases...
Palliative radiotherapy for bone metastases: an ASTRO evidence-based guidelineStephen Lutz
Department of Radiation Oncology, Blanchard Valley Regional Cancer Center, Findlay, OH 45840, USA
Int J Radiat Oncol Biol Phys 79:965-76. 2011..To present guidance for patients and physicians regarding the use of radiotherapy in the treatment of bone metastases according to current published evidence and complemented by expert opinion...
Understanding the EORTC QLQ-BM22, the module for patients with bone metastasesEdward Chow
Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto ON M4N 3M5, Canada
Expert Rev Pharmacoecon Outcomes Res 9:461-5. 2009..Bone metastases clinical trial QoL outcomes will be compared across trials through the utilization of a consistent and valid module questionnaire...
The not-so-crystal ball: the ongoing challenge of physician prognosticationSarah Campos
Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
J Psychosom Res 65:67-9. 2008
Do physicians follow systemic treatment and funding policy guidelines?Mark Clemons
Toronto Sunnybrook Regional Cancer Centre, Canada
Can J Clin Pharmacol 11:e168-78. 2004..In addition we assessed whether or not physicians at these centres are following their local treatment guidelines and funding policies...
Comparison of the efficacy and acute toxicity of weekly versus daily chemoradiotherapy for non-small-cell lung cancer: a meta-analysisEileen Rakovitch
Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 58:196-203. 2004..It remains unknown whether a difference in efficacy or toxicity exists between these approaches. A systematic review was performed to compare the efficacy and toxicity of weekly vs. daily ChRT...
Symptom control and palliative care content of abstracts presented at the Canadian Association of Radiation Oncologists annual meetingsElizabeth A Barnes
Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, 2075 Bayview Avenue, Toronto, Ontario, M4 N 3M5, Canada
Support Care Cancer 12:91-4. 2004..The purpose of this study was to determine the number of abstracts relating to SCPC presented at the annual Canadian Association of Radiation Oncologists (CARO) meetings, and whether this number has increased over time...
Utilization of palliative radiotherapy for breast cancer patients with bone metastases treated with bisphosphonates-Toronto Sunnybrook Regional Cancer Centre experienceKatherine Enright
University of Western Ontario, London, Ontario, Canada
Support Care Cancer 12:48-52. 2004..There is a trend of initiating bisphosphonates before delivery of palliative radiotherapy. The latter was also delivered earlier in the course of bone metastases...
Update on radiation treatment for cancer painEdward Chow
Department of Radiation Oncology, University of Toronto, Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada
Curr Opin Support Palliat Care 1:11-5. 2007..This review addresses the latest advances in radiation treatment for cancer pain...
Palliative radiation therapyAndre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Semin Oncol 32:156-64. 2005..Radiation has also been found to be effective in palliating recurrent cancer that has already received definitive radiation...
Primary treatment endpoint following palliative radiotherapy for painful bone metastases: need for a consensus definition?Jackson S Y Wu
Department of Radiation Oncology, Hamilton Regional Cancer Centre, McMaster University, Ontario, Canada
Clin Oncol (R Coll Radiol) 14:70-7. 2002....
Radiation treatment for breast cancer. Recent advancesEdward Chow
Toronto Sunnybrook Regional Cancer Centre, Department of Radiation Oncology, 2075 Bayview Ave, Toronto, ON M4N 3N5
Can Fam Physician 48:1065-9. 2002..There have been great advances in radiation therapy in the last decade, but they have raised controversy. Further studies are needed to address the controversies...
Role of radiation therapy and radiopharmaceuticals in bone metastasesAlysa Fairchild
Department of Radiation Oncology, University of Alberta, Cross Cancer Institute, Edmonton, Alberta, Canada
Curr Opin Support Palliat Care 1:169-73. 2007..We review recent literature for the treatment of bone metastases and spinal cord compression, and address new developments in the prevention of adverse effects secondary to radiotherapy...
International consensus on palliative radiotherapy endpoints for future clinical trials in bone metastasesEdward Chow
Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Ontario, Canada
Radiother Oncol 64:275-80. 2002..It is intended that the consensus will be re-examined every 5 years. Areas of further research were identified...
A single set of numerical cutpoints to define moderate and severe symptoms for the Edmonton Symptom Assessment SystemDebbie Selby
Palliative Care Department, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario M4N 3M5, Canada
J Pain Symptom Manage 39:241-9. 2010..Across all ESAS symptoms, then, 7 or higher represents a severe symptom by patient definition, whereas a cutpoint of either 4 or 5 could reasonably define combined moderate and severe symptoms...
Symptom distress in patients attending an outpatient palliative radiotherapy clinicNicole Bradley
Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Center, University of Toronto, Toronto, Ontario, Canada
J Pain Symptom Manage 30:123-31. 2005..Symptom assessment tools, such as the ESAS, allow for the identification of symptoms and their severity. The appropriate regimen for management of pain and symptoms in metastatic cancer patients can then be planned...
Review of telephone follow-up experience at the Rapid Response Radiotherapy ProgramEdward Chow
Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
Support Care Cancer 13:549-53. 2005..To review the feasibility of telephone follow-up following a 3-year experience from 1999 to 2001 at the Rapid Response Radiotherapy Program as a prospective radiotherapy outcome assessment of symptom palliation...
Symptom clusters in cancer patients with bone metastasesEdward Chow
Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, ON, Canada
Support Care Cancer 15:1035-43. 2007..The purpose of this study is to explore whether bone pain "clusters" with other symptoms in patients with bone metastases...
Review of patterns of practice and patients' preferences in the treatment of bone metastases with palliative radiotherapyNicole M E Bradley
Department of Health Studies and Gerontology, Faculty of Applied Health Sciences, University of Waterloo, Waterloo, Canada
Support Care Cancer 15:373-85. 2007..Since the 1980s, randomized clinical trials showed that single fraction radiotherapy (RT) provided equal pain relief as multiple fractions of RT in the treatment of bone metastases...
Diarrhea as a radiation side effect "welcomed" by patients taking opioidsKristin Harris
J Pain Symptom Manage 31:97-8. 2006
Palliative treatment of multiple bone metastasisMeagan Doyle
Support Care Cancer 13:199. 2005
Has the pattern of practice in the prescription of radiotherapy for the palliation of thoracic symptoms changed between 1999 and 2006 at the rapid response radiotherapy program?Alysa Fairchild
Rapid Access Palliative Radiotherapy Program, Cross Cancer Institute, Edmonton, Alberta, Canada
Int J Radiat Oncol Biol Phys 70:693-700. 2008..A subsequent RCT assessing 20 Gy/5 found worse survival versus 16 Gy/2. This study examines whether the RT prescription for lung cancer palliation in the Rapid Response Radiotherapy Program (RRRP) has changed over time...
What do patients living with advanced cancer and their carers want to know? - a needs assessmentRebecca K S Wong
University of Toronto, Department of Radiation Oncology, University Health Network, Princess Margaret Hospital, 5th Floor, 610 University Avenue, Toronto, Ontario, M5G 2M9, Canada
Support Care Cancer 10:408-15. 2002..The investment of future effort in evaluating the impact of 1 on 1 interviews and 'short written materials' on the informational needs of patients and carers living with advanced cancer is warranted...
