P W Wales

Summary

Affiliation: The Hospital for Sick Children
Country: Canada

Publications

  1. doi request reprint Is the use of parenteral omega-3 lipid emulsions justified in surgical neonates with mild parenteral nutrition-associated liver dysfunction?
    Ahmed Nasr
    Group for Improvement of Intestinal Function and Treatment GIFT, The Hospital for Sick Children, Toronto, Canada
    J Pediatr Surg 45:980-6. 2010
  2. doi request reprint Delayed primary serial transverse enteroplasty as a novel management strategy for infants with congenital ultra-short bowel syndrome
    Paul W Wales
    Division of Pediatric Surgery, The Hospital for Sick Children, Toronto, Canada, M5G 1X8
    J Pediatr Surg 48:993-9. 2013
  3. doi request reprint Novel lipid-based approaches to pediatric intestinal failure-associated liver disease
    Ivan R Diamond
    Child Health Evaluative Sciences Program, The Hospital for Sick Children, Toronto, Ontario, Canada
    Arch Pediatr Adolesc Med 166:473-8. 2012
  4. doi request reprint Ethanol locks to prevent catheter-related bloodstream infections in parenteral nutrition: a meta-analysis
    Carol Oliveira
    Group for Improvement of Intestinal Function and Treatment GIFT, Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada
    Pediatrics 129:318-29. 2012
  5. doi request reprint Short bowel syndrome: epidemiology and etiology
    Paul W Wales
    Group for Improvement of Intestinal Function and Treatment GIFT, Hospital for Sick Children, Toronto, Ontario, Canada
    Semin Pediatr Surg 19:3-9. 2010
  6. ncbi request reprint Surgical therapy for short bowel syndrome
    Paul W Wales
    Division of General Surgery, The Hospital for Sick Children, 555 University Avenue, Rm 1526, Toronto, Ontario M5G 1X8, Canada
    Pediatr Surg Int 20:647-57. 2004
  7. ncbi request reprint Intermediate outcomes after serial transverse enteroplasty in children with short bowel syndrome
    Paul W Wales
    Division of General Surgery, The Hospital for Sick Children, Toronto, Canada M5G 1X8
    J Pediatr Surg 42:1804-10. 2007
  8. ncbi request reprint Serial transverse enteroplasty as primary therapy for neonates with proximal jejunal atresia
    Paul W Wales
    Division of General Surgery, The Hospital for Sick Children, Toronto, Ontario, M5G 1X8, Canada
    J Pediatr Surg 40:E31-4. 2005
  9. ncbi request reprint Neonatal short bowel syndrome: a cohort study
    Paul W Wales
    Division of General Surgery, The Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8
    J Pediatr Surg 40:755-62. 2005
  10. doi request reprint Ethanol lock therapy to reduce the incidence of catheter-related bloodstream infections in home parenteral nutrition patients with intestinal failure: preliminary experience
    Paul W Wales
    The Group for Improvement of Intestinal Function and Treatment, The Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8
    J Pediatr Surg 46:951-6. 2011

Collaborators

Detail Information

Publications43

  1. doi request reprint Is the use of parenteral omega-3 lipid emulsions justified in surgical neonates with mild parenteral nutrition-associated liver dysfunction?
    Ahmed Nasr
    Group for Improvement of Intestinal Function and Treatment GIFT, The Hospital for Sick Children, Toronto, Canada
    J Pediatr Surg 45:980-6. 2010
    ....
  2. doi request reprint Delayed primary serial transverse enteroplasty as a novel management strategy for infants with congenital ultra-short bowel syndrome
    Paul W Wales
    Division of Pediatric Surgery, The Hospital for Sick Children, Toronto, Canada, M5G 1X8
    J Pediatr Surg 48:993-9. 2013
    ..Congenital ultra-short bowel syndrome (USBS) is a challenging problem with a poor outcome. We report a new management approach for USBS infants that attempts to optimize gut growth potential...
  3. doi request reprint Novel lipid-based approaches to pediatric intestinal failure-associated liver disease
    Ivan R Diamond
    Child Health Evaluative Sciences Program, The Hospital for Sick Children, Toronto, Ontario, Canada
    Arch Pediatr Adolesc Med 166:473-8. 2012
    ..Therefore, there is currently insufficient evidence to support the use of these novel therapies as standard of care in children with no or early IFALD with the goal of preventing the progression of liver disease...
  4. doi request reprint Ethanol locks to prevent catheter-related bloodstream infections in parenteral nutrition: a meta-analysis
    Carol Oliveira
    Group for Improvement of Intestinal Function and Treatment GIFT, Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada
    Pediatrics 129:318-29. 2012
    ....
  5. doi request reprint Short bowel syndrome: epidemiology and etiology
    Paul W Wales
    Group for Improvement of Intestinal Function and Treatment GIFT, Hospital for Sick Children, Toronto, Ontario, Canada
    Semin Pediatr Surg 19:3-9. 2010
    ..There are very few estimates of SBS incidence and mortality in the literature. The epidemiology of SBS is reviewed and the limitations of the published literature are discussed...
  6. ncbi request reprint Surgical therapy for short bowel syndrome
    Paul W Wales
    Division of General Surgery, The Hospital for Sick Children, 555 University Avenue, Rm 1526, Toronto, Ontario M5G 1X8, Canada
    Pediatr Surg Int 20:647-57. 2004
    ..The goal of this review article is to summarize the process of intestinal adaptation and then to outline the surgical principles and techniques available to surgeons who treat this complicated group of patients...
  7. ncbi request reprint Intermediate outcomes after serial transverse enteroplasty in children with short bowel syndrome
    Paul W Wales
    Division of General Surgery, The Hospital for Sick Children, Toronto, Canada M5G 1X8
    J Pediatr Surg 42:1804-10. 2007
    ..The aim of this study was to report intermediate outcomes in patients who have received the STEP at our institution using clinical and biochemical assessment of intestinal function...
  8. ncbi request reprint Serial transverse enteroplasty as primary therapy for neonates with proximal jejunal atresia
    Paul W Wales
    Division of General Surgery, The Hospital for Sick Children, Toronto, Ontario, M5G 1X8, Canada
    J Pediatr Surg 40:E31-4. 2005
    ....
  9. ncbi request reprint Neonatal short bowel syndrome: a cohort study
    Paul W Wales
    Division of General Surgery, The Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8
    J Pediatr Surg 40:755-62. 2005
    ..By applying more rigorous methodology, our aim was to determine outcomes of SBS neonates compared with a control group of neonates without SBS...
  10. doi request reprint Ethanol lock therapy to reduce the incidence of catheter-related bloodstream infections in home parenteral nutrition patients with intestinal failure: preliminary experience
    Paul W Wales
    The Group for Improvement of Intestinal Function and Treatment, The Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8
    J Pediatr Surg 46:951-6. 2011
    ..Ethanol lock of central venous catheters may decrease CRBSI, but limited pediatric data are available...
  11. ncbi request reprint Percutaneous cholangiography for the treatment of parenteral nutrition-associated cholestasis in surgical neonates: preliminary experience
    Paul W Wales
    Division of General Surgery, Faculty of Medicine, The Hospital for Sick Children, University of Toronto, Toronto, ON M5G 1X8, Canada
    J Pediatr Surg 42:1913-8. 2007
    ..Our aim was to evaluate the effectiveness of percutaneous transhepatic transcholecystic cholangiography (PTTC) in the treatment of PNAC in surgical neonates...
  12. doi request reprint Advantages of the distal sigmoid colostomy in the management of infants with short bowel syndrome
    Ivan R Diamond
    Division of General Surgery, Group for Improvement of Intestinal Function and Treatment, Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Canada
    J Pediatr Surg 43:1464-7. 2008
    ..Restoring intestinal continuity may create difficulty with perineal soiling. We propose creation of a distal sigmoid colostomy as an option for select infants with SBS...
  13. doi request reprint Establishing norms for intestinal length in children
    Marie Chantal Struijs
    Group for Improvement of Intestinal Function and Treatment, The Hospital for Sick Children, Toronto, Canada
    J Pediatr Surg 44:933-8. 2009
    ..Existing data on pediatric intestinal length (IL) are limited because most studies report postmortem values. Using prospective data, appropriate norms for IL were developed...
  14. ncbi request reprint The use of conjugated hyperbilirubinemia greater than 100 micromol/L as an indicator of irreversible liver disease in infants with short bowel syndrome
    Ahmed Nasr
    Division of General Surgery, Faculty of Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Canada M5G 1X8
    J Pediatr Surg 42:359-62. 2007
    ..Knowledge of when to refer such children for evaluation for transplantation is crucial. A commonly used criterion is conjugated hyperbilirubinemia greater than 100 micromol/L (CB100)...
  15. doi request reprint Changing the paradigm: omegaven for the treatment of liver failure in pediatric short bowel syndrome
    Ivan R Diamond
    The Hospital for Sick Children, Toronto, Canada
    J Pediatr Gastroenterol Nutr 48:209-15. 2009
    ..Parenteral omega-3 fatty acids, such as Omegaven, may benefit patients with pediatric short bowel syndrome (SBS) who develop parenteral nutrition-associated liver disease (PNALD)...
  16. doi request reprint Routine use of a SILASTIC spring-loaded silo for infants with gastroschisis: a multicenter randomized controlled trial
    Aimee C Pastor
    Pediatric General Surgery, Hospital for Sick Children, Toronto, ON, Canada
    J Pediatr Surg 43:1807-12. 2008
    ..Retrospective studies have suggested that routine use of a preformed silo for infants with gastroschisis may be associated with improved outcomes. We performed a prospective multicenter randomized controlled trial to test this hypothesis...
  17. ncbi request reprint What is the current role for parenteral lipid emulsions containing omega-3 fatty acids in infants with short bowel syndrome?
    I R Diamond
    Group for Improvement of Intestinal Function and Treatment GIFT, Hospital for Sick Children, Toronto, ON, Canada
    Minerva Pediatr 61:263-72. 2009
    ..Given the promising results and apparent safety of these emulsions, we shall also consider what the current role for PN lipid emulsions containing w3FA in children with SBS should be...
  18. ncbi request reprint Neonatal short bowel syndrome: population-based estimates of incidence and mortality rates
    Paul W Wales
    Division of General Surgery, The Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Surg 39:690-5. 2004
    ..No accurate population estimates of incidence and mortality exist because of differences in definition, follow-up, and regional referral patterns...
  19. doi request reprint Absence of the interstitial cells of Cajal in a child with chronic pseudoobstruction
    Marie Chantal Struijs
    Group for Improvement of Intestinal Function and Treatment GIFT, The Hospital for Sick Children, Toronto, Canada M5G 1X8
    J Pediatr Surg 43:e25-9. 2008
    ..This report highlights that abnormalities of the ICCs in intestinal pseudoobstruction should be considered early in the diagnostic workup of children with intestinal pseudoobstruction...
  20. ncbi request reprint Population demographic indicators associated with incidence of pyloric stenosis
    Teresa To
    Population Health Sciences, Research Institute and Departments of Surgery and Pediatrics, Hospital for Sick Children, Toronto, Ontario
    Arch Pediatr Adolesc Med 159:520-5. 2005
    ..To calculate incidence rates of pyloric stenosis (estimated by the rate of pyloromyotomy) among infants in Ontario and determine their association with population sociodemographic indicators...
  21. doi request reprint Does the colon play a role in intestinal adaptation in infants with short bowel syndrome? A multiple variable analysis
    Ivan R Diamond
    Group for Improvement of Intestinal Function and Treatment GIFT, The Hospital for Sick Children, Toronto, Canada M5G 1X8
    J Pediatr Surg 45:975-9. 2010
    ..We sought to examine in a multiple variable model the impact of residual colonic length on time to intestinal adaptation in a cohort of infants with short bowel syndrome...
  22. ncbi request reprint Long-term outcome after nonoperative management of complete traumatic pancreatic transection in children
    P W Wales
    Division of Pediatric General Surgery and Department of Radiology, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Surg 36:823-7. 2001
    ..To the authors' knowledge, this is the first report to show the effectiveness of nonoperative management after complete pancreatic transection...
  23. doi request reprint What's the incidence of delayed splenic bleeding in children after blunt trauma? An institutional experience and review of the literature
    Dafydd A Davies
    Division of General Surgery, Hospital for Sick Children, Toronto, Ontario, Canada
    J Trauma 67:573-7. 2009
    ..The existence and incidence of delayed splenic bleeding (DSB) in children are controversial but the implications are significant. We sought to determine the incidence of DSB in children and to look for similarities between reported cases...
  24. ncbi request reprint The versatility of the umbilical incision in the management of Hirschsprung's disease
    Carolien J E Sauer
    Division of General Surgery, Hospital for Sick Children, Toronto, Ontario, M5G 1X8, Canada
    J Pediatr Surg 40:385-9. 2005
    ..The aim of this report is to describe how the umbilical incision provides a quick and safe alternative to laparoscopy or other abdominal incisions in the management of Hirschsprung's disease (HD)...
  25. doi request reprint Pediatric blunt and penetrating trauma deaths in Ontario: a population-based study
    Ivan R Diamond
    The Hospital for Sick Children, Toronto, Canada
    J Pediatr Surg 44:981-6. 2009
    ..The purpose of the study was to describe the mechanisms of injury and causes of death in children dying in a modern, integrated trauma system...
  26. doi request reprint Predictors of metachronous inguinal hernias in children
    Mohammed Zamakhshardy
    Division of General Surgery, The Hospital for Sick Children, Room 1526, 555 University Avenue, Toronto, ON, M5G 1X8, Canada
    Pediatr Surg Int 25:69-71. 2009
    ..Surgical management of the contralateral groin in unilateral inguinal hernia remains controversial. Our aim was to determine predictors of metachronous inguinal hernias in children using multivariable analysis...
  27. ncbi request reprint Fundoplication and gastrostomy versus image-guided gastrojejunal tube for enteral feeding in neurologically impaired children with gastroesophageal reflux
    Paul W Wales
    Division of Pediatric General Surgery and the Department Diagnostic Imaging, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Surg 37:407-12. 2002
    ..The authors evaluated the image-guided gastrojejunal tube (GJ) as an alternative approach for this group of patients...
  28. ncbi request reprint Neonatal short bowel syndrome outcomes after the establishment of the first Canadian multidisciplinary intestinal rehabilitation program: preliminary experience
    Ivan R Diamond
    Division of General Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8
    J Pediatr Surg 42:806-11. 2007
    ....
  29. ncbi request reprint Lung torsion after tracheoesophageal fistula repair: a case report and review of literature
    Carol Oliveira
    Division of General Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Surg 42:E5-9. 2007
    ..Patients with complete interlobar fissures may benefit from pulmonary lobe fixation as a prophylaxis against occurrence or recurrence of this complication...
  30. ncbi request reprint Isolated liver transplantation in pediatric short bowel syndrome: is there a role?
    Ivan R Diamond
    Group for the Improvement of Intestinal Function and Treatment GIFT and the Pediatric Academic Multi organ Transplant Program, Division of General Surgery, The Hospital for Sick Children, Toronto, Canada M5G 1X8
    J Pediatr Surg 41:955-9. 2006
    ..The role of isolated liver transplantation in infants with parenteral nutrition-associated cholestasis (PNAC) associated with short bowel syndrome (SBS) is unclear...
  31. ncbi request reprint The optimal timing of intestinal transplantation for children with intestinal failure: a Markov analysis
    Steven R Lopushinsky
    Department of Surgery, Hospital for Sick Children, Toronto, Ontario, Canada
    Ann Surg 246:1092-9. 2007
    ..Identify an optimal approach to the timing of intestinal transplantation for children dependent on total parenteral nutrition (PN)...
  32. doi request reprint The rationale for the use of parenteral omega-3 lipids in children with short bowel syndrome and liver disease
    Ivan R Diamond
    Group for Improvement of Intestinal Function and Treatment GIFT, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, Canada, M5G 1X8
    Pediatr Surg Int 24:773-8. 2008
    ..The early clinical experience with omega3FAs in SBS and PNALD is briefly reviewed and the implications of such, and future directions are considered...
  33. doi request reprint Ectopic drainage of the common bile duct into the lesser curvature of the gastric antrum in a newborn with pyloric atresia, annular pancreas and congenital short bowel syndrome
    Nicola Scheida
    Department of Diagnostic Imaging, Division of Image Guided Therapy, The Hospital for Sick Children, 555 University Ave, Toronto M5G 1X8, Canada
    Pediatr Radiol 39:66-9. 2009
    ..Radiologic, sonographic and percutaneous transhepatic transcholecystic cholangiographic (PTTC) findings, with surgical correlation, are presented...
  34. ncbi request reprint Predicting the need for fundoplication at the time of congenital diaphragmatic hernia repair
    Ivan R Diamond
    Division of General Surgery, The Hospital for Sick Children, Toronto, Canada M5G 1X8
    J Pediatr Surg 42:1066-70. 2007
    ..This study was conducted to examine the preoperative factors predictive of subsequent intervention for gastroesophageal reflux (GER) in children with congenital diaphragmatic hernia (CDH)...
  35. ncbi request reprint Survival after CCAM associated with ascites: a report of a case and review of the literature
    Ivan R Diamond
    Division of Pediatric General Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Surg 38:E1-3. 2003
    ..This has important implications for prenatal counseling particularly in centers in which fetal intervention is not available...
  36. ncbi request reprint Understanding neonatal bowel obstruction: building knowledge to advance practice
    Nicole T de Silva
    NICU, Hospital for Sick Children, Ontario, Canada
    Neonatal Netw 25:303-18. 2006
    ..This article describes features of the neonatal GI tract and discusses common causes of neonatal bowel obstruction...
  37. ncbi request reprint The use of Surgisis for abdominal wall reconstruction in the separation of omphalopagus conjoined twins
    Roshni Dasgupta
    Division of Pediatric General Surgery, Hospital for Sick Children, Toronto, ON, Canada
    Pediatr Surg Int 23:923-6. 2007
    ..Surgisis can be successfully used for the reconstruction of complex abdominal wall defects in the pediatric patient, including reconstruction after separation of conjoined twins...
  38. doi request reprint Omega-3 lipids for intestinal failure associated liver disease
    Ivan R Diamond
    Group for Improvement of Intestinal Function and Treatment GIFT, The Hospital for Sick Children, Toronto, Canada
    Semin Pediatr Surg 18:239-45. 2009
    ..Mechanisms explaining their effects will be considered as will future research directions...
  39. ncbi request reprint Outcomes and management of rectal injuries in children
    Arnaud Bonnard
    Division of General Surgery, Hospital for Sick Children, Room 1526, 555 University Avenue, Toronto, ON, Canada M5G 1X8
    Pediatr Surg Int 23:1071-6. 2007
    ..Laparoscopy may be used for the immediate management of the penetrating trauma patient to rule out intraperitoneal extension, repair a perforation and guide the colostomy if necessary...
  40. doi request reprint Delayed, life-threatening lower gastrointestinal hemorrhage in an infant after serial transverse enteroplasty: treatment with transcatheter n-butyl-2-cyanoacrylate embolization
    Conor O Bogue
    Division of Image Guided Therapy, Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto M5G 1X8, Canada
    Pediatr Radiol 39:1098-101. 2009
    ..To the best of our knowledge this is both the first report of successful glue embolization for LGI bleeding in a child and also the first report of severe hemorrhage after the STEP procedure...
  41. doi request reprint Management of blunt splenic injury in children: evolution of the nonoperative approach
    Dafydd A Davies
    Division of Pediatric General Surgery, The Hospital for Sick Children, Toronto, ON, Canada
    J Pediatr Surg 44:1005-8. 2009
    ..Since that time, treatment of patients with BSI has evolved from routine splenectomy to an aggressive spleen-preserving philosophy. This report summarizes our institutional experience for the last 50 years...
  42. doi request reprint Preventable pediatric trauma deaths in Ontario: a comparative population-based study
    Ivan R Diamond
    Division of General Surgery, The Hospital for Sick Children, Toronto, Canada
    J Trauma 66:1189-94; discussion 1194-5. 2009
    ..This study aims to examine the current preventable trauma death rate in our system using identical methodology to our previous study...
  43. ncbi request reprint Nonoperative management of perianal abscess in infants is associated with decreased risk for fistula formation
    Emily R Christison-Lagay
    Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Pediatrics 120:e548-52. 2007
    ..We sought to determine the frequency of progression in infants of perianal abscess with and without surgical drainage to fistula in ano to optimize a treatment plan for these children...