R Tannock

Summary

Affiliation: The Hospital for Sick Children
Country: Canada

Publications

  1. ncbi request reprint Methylphenidate improves visual-spatial memory in children with attention-deficit/hyperactivity disorder
    Anne Claude Bedard
    Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada
    J Am Acad Child Adolesc Psychiatry 43:260-8. 2004
  2. ncbi request reprint Attention deficit hyperactivity disorder: advances in cognitive, neurobiological, and genetic research
    R Tannock
    Department of Psychiatry Research Unit, Hospital for Sick Children, Toronto, Ontario, Canada
    J Child Psychol Psychiatry 39:65-99. 1998
  3. ncbi request reprint Methylphenidate improves Stroop naming speed, but not response interference, in children with attention deficit hyperactivity disorder
    Anne Claude Bedard
    Institute of Medical Science, The University of Toronto and Brain and Behaviour Research Unit, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Child Adolesc Psychopharmacol 12:301-9. 2002
  4. ncbi request reprint Naming speed performance and stimulant effects indicate effortful, semantic processing deficits in attention-deficit/hyperactivity disorder
    R Tannock
    Brain and Behavior Research Program, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Abnorm Child Psychol 28:237-52. 2000
  5. doi request reprint Association of ADHD and the Protogenin gene in the chromosome 15q21.3 reading disabilities linkage region
    K G Wigg
    Genetics and Development Division, The Toronto Western Research Institute, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Genes Brain Behav 7:877-86. 2008
  6. ncbi request reprint Association of the dopamine receptor D1 gene, DRD1, with inattention symptoms in families selected for reading problems
    P Luca
    Cell and Molecular Biology Division, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada
    Mol Psychiatry 12:776-85. 2007
  7. ncbi request reprint Association study of the nicotinic acetylcholine receptor alpha4 subunit gene, CHRNA4, in attention-deficit hyperactivity disorder
    J Lee
    Division of Genetics and Development, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada
    Genes Brain Behav 7:53-60. 2008
  8. ncbi request reprint Association of the glutamate receptor subunit gene GRIN2B with attention-deficit/hyperactivity disorder
    K M Dorval
    Cell and Molecular Biology Division, Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    Genes Brain Behav 6:444-52. 2007
  9. ncbi request reprint Association of the calcyon gene (DRD1IP) with attention deficit/hyperactivity disorder
    N Laurin
    Cell and Molecular Biology Division, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada
    Mol Psychiatry 10:1117-25. 2005
  10. ncbi request reprint Further evidence from haplotype analysis for linkage of the dopamine D4 receptor gene and attention-deficit hyperactivity disorder
    C L Barr
    Department of Psychiatry, The Toronto Hospital, Western Division, Ontario, Canada
    Am J Med Genet 96:262-7. 2000

Research Grants

Collaborators

Detail Information

Publications68

  1. ncbi request reprint Methylphenidate improves visual-spatial memory in children with attention-deficit/hyperactivity disorder
    Anne Claude Bedard
    Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada
    J Am Acad Child Adolesc Psychiatry 43:260-8. 2004
    ..Visual-spatial memory is a core component of working memory that has been shown to be impaired in ADHD, irrespective of comorbid reading and/or language problems...
  2. ncbi request reprint Attention deficit hyperactivity disorder: advances in cognitive, neurobiological, and genetic research
    R Tannock
    Department of Psychiatry Research Unit, Hospital for Sick Children, Toronto, Ontario, Canada
    J Child Psychol Psychiatry 39:65-99. 1998
    ..The review closes with suggestions for future interdisciplinary research...
  3. ncbi request reprint Methylphenidate improves Stroop naming speed, but not response interference, in children with attention deficit hyperactivity disorder
    Anne Claude Bedard
    Institute of Medical Science, The University of Toronto and Brain and Behaviour Research Unit, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Child Adolesc Psychopharmacol 12:301-9. 2002
    ..Response interference is a core component of response inhibition that has been shown to be impaired in children with ADHD...
  4. ncbi request reprint Naming speed performance and stimulant effects indicate effortful, semantic processing deficits in attention-deficit/hyperactivity disorder
    R Tannock
    Brain and Behavior Research Program, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Abnorm Child Psychol 28:237-52. 2000
    ..These findings challenge the tenet that naming speed deficits are specific to RD and implicate naming speed deficits associated with effortful semantic processing in ADHD, which are improved but not normalized by stimulant medication...
  5. doi request reprint Association of ADHD and the Protogenin gene in the chromosome 15q21.3 reading disabilities linkage region
    K G Wigg
    Genetics and Development Division, The Toronto Western Research Institute, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Genes Brain Behav 7:877-86. 2008
    ..These findings, while preliminary, identify association of ADHD to a gene that potentially plays a role in cell migration and axon growth...
  6. ncbi request reprint Association of the dopamine receptor D1 gene, DRD1, with inattention symptoms in families selected for reading problems
    P Luca
    Cell and Molecular Biology Division, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada
    Mol Psychiatry 12:776-85. 2007
    ..Furthermore, the association of DRD1 with inattention, but not with RD, or the other reading and reading-related phenotypes analysed, suggests that DRD1 contributes uniquely to inattention, without overlap for reading ability...
  7. ncbi request reprint Association study of the nicotinic acetylcholine receptor alpha4 subunit gene, CHRNA4, in attention-deficit hyperactivity disorder
    J Lee
    Division of Genetics and Development, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada
    Genes Brain Behav 7:53-60. 2008
    ..Based on our results and others, CHRNA4 may be involved in ADHD; however, its role in ADHD symptomatology remains to be clarified...
  8. ncbi request reprint Association of the glutamate receptor subunit gene GRIN2B with attention-deficit/hyperactivity disorder
    K M Dorval
    Cell and Molecular Biology Division, Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    Genes Brain Behav 6:444-52. 2007
    ..Our data suggest an association between variations in the GRIN2B subunit gene and ADHD as measured categorically or as a quantitatively distributed trait...
  9. ncbi request reprint Association of the calcyon gene (DRD1IP) with attention deficit/hyperactivity disorder
    N Laurin
    Cell and Molecular Biology Division, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada
    Mol Psychiatry 10:1117-25. 2005
    ..These findings support the proposed involvement of the calcyon gene in ADHD and implicate haplotype C1 as containing a risk allele...
  10. ncbi request reprint Further evidence from haplotype analysis for linkage of the dopamine D4 receptor gene and attention-deficit hyperactivity disorder
    C L Barr
    Department of Psychiatry, The Toronto Hospital, Western Division, Ontario, Canada
    Am J Med Genet 96:262-7. 2000
    ..We examined the haplotypes of three polymorphisms of the D4 receptor gene and observed biased transmission of two of these haplotypes. Our findings further support the role of the dopamine D4 gene in ADHD...
  11. ncbi request reprint Linkage study of polymorphisms in the gene for myelin oligodendrocyte glycoprotein located on chromosome 6p and attention deficit hyperactivity disorder
    C L Barr
    Department of Psychiatry, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
    Am J Med Genet 105:250-4. 2001
    ..We did not observe biased transmission of the alleles at either polymorphism to ADHD probands or siblings. Our findings using this sample do not support the role of the MOG gene in ADHD...
  12. ncbi request reprint Linkage study of catechol-O-methyltransferase and attention-deficit hyperactivity disorder
    C L Barr
    Department of Psychiatry, Toronto Hospital, Western Division, Toronto, Ontario, Canada
    Am J Med Genet 88:710-3. 1999
    ..A total of 77 nuclear families collected from Toronto were genotyped. We find no evidence for linkage of this polymorphism and ADHD in our sample. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 88:710-713, 1999...
  13. ncbi request reprint Attention-deficit hyperactivity disorder and the gene for the dopamine D5 receptor
    C L Barr
    Department of Psychiatry, The Toronto Western Hospital, Ontario, Canada
    Mol Psychiatry 5:548-51. 2000
    ..The number of informative transmissions for these two alleles was small, therefore it would be premature to make any conclusions from our study concerning the role of DRD5 in ADHD...
  14. ncbi request reprint The SNAP25 gene as a susceptibility gene contributing to attention-deficit hyperactivity disorder
    Y Feng
    Department of Psychiatry, Cellular and Molecular Division, The Toronto Western Research Institute, University Health Network, Toronto, ON, Canada
    Mol Psychiatry 10:998-1005, 973. 2005
    ..Our findings continue to support SNAP25 in the susceptibility to ADHD...
  15. ncbi request reprint 5'-untranslated region of the dopamine D4 receptor gene and attention-deficit hyperactivity disorder
    C L Barr
    Department of Psychiatry, The Toronto Western Hospital, Ontario, Canada
    Am J Med Genet 105:84-90. 2001
    ..We conclude that these three polymorphisms are not related to the ADHD phenotype...
  16. ncbi request reprint Glutamate receptor, ionotropic, N-methyl D-aspartate 2A (GRIN2A) gene as a positional candidate for attention-deficit/hyperactivity disorder in the 16p13 region
    J Adams
    Cell and Molecular Biology Division, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada
    Mol Psychiatry 9:494-9. 2004
    ..There was no significant evidence of linkage between GRIN2A and these phenotypes. While the results were not significant in our sample, the previous association finding suggests that further study of this gene is warranted...
  17. ncbi request reprint Linkage study of the alpha2A adrenergic receptor in attention-deficit hyperactivity disorder families
    C Xu
    Department of Psychiatry, Division of Cellular and Molecular Biology, The Toronto Western Hospital, Toronto, Canada
    Am J Med Genet 105:159-62. 2001
    ..We found no evidence for linkage of the ADRA2A gene with ADHD, using the transmission disequilibrium test in this set of families...
  18. ncbi request reprint Linkage study of two polymorphisms at the dopamine D3 receptor gene and attention-deficit hyperactivity disorder
    C L Barr
    Department of Psychiatry, The Toronto Hospital, Western Division, Toronto, Ontario, Canada
    Am J Med Genet 96:114-7. 2000
    ..Our findings using this particular sample do not support the role of the dopamine D3 gene in ADHD. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:114-117, 2000...
  19. ncbi request reprint Attention-deficit hyperactivity disorder and the adrenergic receptors alpha 1C and alpha 2C
    C L Barr
    Department of Psychiatry, The Toronto Western Hospital, Toronto, Ontario, Canada
    Mol Psychiatry 6:334-7. 2001
    ..We conclude that the alleles at the polymorphisms tested in these two genes are not linked to the ADHD phenotype in this sample of families...
  20. doi request reprint Sex differences in sensorimotor mu rhythms during selective attentional processing
    C Popovich
    Neurosciences and Mental Health Program, The Hospital for Sick Children, Toronto, ON, Canada
    Neuropsychologia 48:4102-10. 2010
    ..These sex differences in attention to somatosensory stimuli may help elucidate the well-documented sex biases in pain processing wherein females typically report greater sensitivity to experimental and clinical pain...
  21. ncbi request reprint Methylphenidate selectively improves story retelling in children with attention deficit hyperactivity disorder
    S Francis
    Brain and Behavior Research Department, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Child Adolesc Psychopharmacol 11:217-28. 2001
    ..CONCLUSION: Story grammar analysis was sensitive to drug effects, which were subtle but specific and clinically meaningful. Results provide evidence for the theoretical linkage between internal responses and attempts...
  22. doi request reprint Effects of a computerized working memory training program on working memory, attention, and academics in adolescents with severe LD and comorbid ADHD: a randomized controlled trial
    S A Gray
    Neurosciences and Mental Health Research Program, SickKids Hospital, Toronto, ON, Canada
    J Child Psychol Psychiatry 53:1277-84. 2012
    ..Emerging evidence suggests that WM might be improved by intensive and adaptive computerized training, but it remains unclear whether this intervention would be effective for adolescents with severe LD and comorbid ADHD...
  23. ncbi request reprint Support for EKN1 as the susceptibility locus for dyslexia on 15q21
    K G Wigg
    Department of Psychiatry, Cell and Molecular Division, The Toronto Western Hospital, University Health Network, Toronto, Ontario M5T 2S8, Canada
    Mol Psychiatry 9:1111-21. 2004
    ..Based on these findings, further studies of this gene in independent samples are now required to determine the relationship of this gene to dyslexia...
  24. ncbi request reprint Confirmation of an inhibitory control deficit in attention-deficit/hyperactivity disorder
    R Schachar
    Department of Psychiatry and the Brain and Behavior Program, The Hospital for Sick Children and the University of Toronto, Ontario, Canada
    J Abnorm Child Psychol 28:227-35. 2000
    ..These results indicate that children with ADHD have deficient inhibition as measured in the stop-signal paradigm and that ADHD occurring in the presence of ADHD + CD may represent a phenocopy of CD rather than a variant of ADHD...
  25. ncbi request reprint Psychiatric, psychosocial, and cognitive functioning of female adolescents with ADHD
    J J Rucklidge
    Hospital for Sick Children, Brain and Behaviour Reseacrh, Toronto, Canada
    J Am Acad Child Adolesc Psychiatry 40:530-40. 2001
    ..Female controls were also compared with male controls to verify gender differences in a nonclinical sample...
  26. ncbi request reprint Time perception deficits in attention-deficit/ hyperactivity disorder and comorbid reading difficulties in child and adolescent samples
    M E Toplak
    Brain and Behaviour Research Programme, Research Institute of the Hospital for Sick Children, Toronto, Canada
    J Child Psychol Psychiatry 44:888-903. 2003
    ..Our objective was to investigate time perception in Attention-Deficit/Hyperactivity Disorder (ADHD) with and without comorbid reading difficulties (RD) in child and adolescent participants...
  27. doi request reprint Cortical dynamics of selective attention to somatosensory events
    C Dockstader
    Neuroscience and Mental Health program, The Hospital for Sick Children, 555 University Avenue, Room 4265, Toronto, Ontario, Canada M5G 1X8
    Neuroimage 49:1777-85. 2010
    ....
  28. ncbi request reprint Linkage of the dopamine receptor D1 gene to attention-deficit/hyperactivity disorder
    V L Misener
    Cell and Molecular Biology Division, Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    Mol Psychiatry 9:500-9. 2004
    ..DNA from 41 children was analysed, and no sequence variations were identified, indicating that the putative DRD1 risk variant for ADHD resides outside of the coding region of the gene...
  29. ncbi request reprint The attributions of children with Attention-Deficit/ Hyperactivity Disorder for their problem behaviors
    I Kaidar
    Department of Human Development and Applied Psychology at the Ontario Institute for Studies in Education of the University of Toronto, Ontario, Canada
    J Atten Disord 6:99-109. 2003
    ..With regards to stigmatization, girls without ADHD reported that their behaviors can bother their teachers, parents, and peers, whereas girls and boys with ADHD did not perceive their behavior as bothersome...
  30. ncbi request reprint Haplotype study of three polymorphisms at the dopamine transporter locus confirm linkage to attention-deficit/hyperactivity disorder
    C L Barr
    Department of Psychiatry, The Toronto Western Hospital, Toronto, Canada
    Biol Psychiatry 49:333-9. 2001
    ..This association was later replicated in additional studies...
  31. ncbi request reprint Selective inhibition in children with attention-deficit hyperactivity disorder off and on stimulant medication
    Anne Claude Bedard
    Institute of Medical Science, The University of Toronto, Toronto, Canada
    J Abnorm Child Psychol 31:315-27. 2003
    ..On the one hand, findings are consistent with purported inhibition deficit in ADHD, but on the other hand, suggest that neither the impairment itself, nor MPH effects, were restricted to inhibition...
  32. ncbi request reprint ADHD outside the laboratory: boys' executive function performance on tasks in videogame play and on a visit to the zoo
    Vivienne Lawrence
    The Graduate School of Education, The University of Western Australia, Perth
    J Abnorm Child Psychol 30:447-62. 2002
    ..Findings from this study suggest that cognitive difficulties in ADHD may be context dependent and that ADHD is associated with deficits in some but not all aspects of behavioral inhibition...
  33. ncbi request reprint Anxiety, methylphenidate response, and working memory in children with ADHD
    Anne Claude Bedard
    University of Toronto, Canada, Hospital for Sick Children, Toronto, Canada
    J Atten Disord 11:546-57. 2008
    ..To investigate the effects of methylphenidate (MPH) on components of working memory (WM) in children with ADHD and determine whether MPH produces differential effects on WM in children with comorbid anxiety (ANX)...
  34. ncbi request reprint Reaction time performance in adolescents with attention deficit/hyperactivity disorder: evidence of inconsistency in the fast and slow portions of the RT distribution
    Benjamin R Williams
    University of Victoria, Victoria, British Columbia, Canada
    J Clin Exp Neuropsychol 29:277-89. 2007
    ..The results highlight the importance of fluctuations in cognitive performance in ADHD and suggest that there may be independent sources of variation in inconsistency affecting the fast and slow portions of the RT distribution...
  35. ncbi request reprint Neuropsychological profiles of adolescents with ADHD: effects of reading difficulties and gender
    Julia J Rucklidge
    The Hospital for Sick Children, Toronto, Canada
    J Child Psychol Psychiatry 43:988-1003. 2002
    ..Females may be less impaired in executive function although adolescent females with ADHD have yet to be studied...
  36. ncbi request reprint Preliminary evidence of beneficial effects of methylphenidate on listening comprehension in children with attention-deficit/hyperactivity disorder
    Alison McInnes
    Faculty of Education, University of Windsor, Windsor, Ontario, Canada
    J Child Adolesc Psychopharmacol 17:35-49. 2007
    ..The effect of methylphenidate (MPH) on listening comprehension for information passages, and on working memory, was examined in a clinical sample of 16 children with attention-deficit/hyperactivity disorder (ADHD)...
  37. ncbi request reprint Effects of methylphenidate on working memory components: influence of measurement
    Anne Claude Bedard
    Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada
    J Child Psychol Psychiatry 48:872-80. 2007
    ..To investigate the effects of methylphenidate (MPH) on components of working memory (WM) in attention-deficit hyperactivity disorder (ADHD) and determine the responsiveness of WM measures to MPH...
  38. ncbi request reprint The gene for synapsin III and attention-deficit hyperactivity disorder
    Rohit Makkar
    Cell and Molecular Biology Division, Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    Psychiatr Genet 17:109-12. 2007
    ..On the basis of the role of synapsin III in the modulation of neurotransmitter release, we tested this gene as a candidate contributing to the genetic susceptibility of attention deficit hyperactivity disorder...
  39. ncbi request reprint Attention deficit hyperactivity disorder and the gene for dopamine Beta-hydroxylase
    Karen Wigg
    Department of Psychiatry, Toronto Western Hospital, Ont, Canada
    Am J Psychiatry 159:1046-8. 2002
    ..One recent study reported an association of an allele of the TaqI polymorphism located in the fifth intron of the gene for dopamine beta-hydroxylase (DBH). The authors' goal was to replicate this finding...
  40. ncbi request reprint Age of onset of ADHD symptoms
    Julia J Rucklidge
    J Am Acad Child Adolesc Psychiatry 41:496-7. 2002
  41. ncbi request reprint The development of selective inhibitory control across the life span
    Anne Claude Bedard
    The Hospital for Sick Children, Toronto, Canada
    Dev Neuropsychol 21:93-111. 2002
    ..Findings are discussed in regard to the decay and maturation of selective inhibitory control across the life span...
  42. ncbi request reprint Association study of the brain-derived neurotropic factor (BDNF) gene in attention deficit hyperactivity disorder
    Jonghun Lee
    Cell and Molecular Biology Division, Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    Am J Med Genet B Neuropsychiatr Genet 144:976-81. 2007
    ..651, P = 0.008). These results should be interpreted cautiously, however, because of the low haplotype frequency. In light of the evidence for an involvement of BDNF in ADHD, further analysis of the BDNF gene in ADHD is warranted...
  43. ncbi request reprint No evidence for genetic association between DARPP-32 (PP1R1B) polymorphisms and attention deficit hyperactivity disorder
    Nancy Laurin
    Division of Genetics and Development, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada
    Am J Med Genet B Neuropsychiatr Genet 147:339-42. 2008
    ..In conclusion, albeit a key regulatory role in dopamine signaling, our data do not support a major contribution of the DARPP-32 gene in ADHD...
  44. ncbi request reprint Association study for genes at chromosome 5p13-q11 in attention deficit hyperactivity disorder
    Nancy Laurin
    Genetics and Development Division, The Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    Am J Med Genet B Neuropsychiatr Genet 147:600-5. 2008
    ..Our results suggest that these six genes are unlikely to be susceptibility genes in the chromosome 5p13-q11 region and other genes should now be considered for priority study...
  45. ncbi request reprint The sounds of silence: language, cognition, and anxiety in selective mutism
    Katharina Manassis
    The Hospital for Sick Children and the University of Toronto, 555 University Avenue, Toronto, Ontario, Canada
    J Am Acad Child Adolesc Psychiatry 46:1187-95. 2007
    ..To determine whether oral language, working memory, and social anxiety differentiate children with selective mutism (SM), children with anxiety disorders (ANX), and normal controls (NCs) and explore predictors of mutism severity...
  46. doi request reprint Neurobiology of attention deficit hyperactivity disorder
    Christian Kieling
    Department of Psychiatry, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2350 2201A 90035 903, Porto Alegre, RS, Brazil
    Child Adolesc Psychiatr Clin N Am 17:285-307, viii. 2008
    ..Finally, the article addresses the longitudinal course of symptoms in ADHD from infancy to adulthood in an attempt to place biological findings for this complex brain disorder in the context of maturation and development...
  47. ncbi request reprint The norepinephrine transporter gene and attention-deficit hyperactivity disorder
    Cathy L Barr
    Department of Psychiatry and Division of Cellular and Molecular Biology, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
    Am J Med Genet 114:255-9. 2002
    ..8%) was similar to that previously reported in a control sample (2.2%), it is unlikely that this variant is related to the ADHD phenotype. Our results do not support the NET1 gene as a major genetic susceptibility factor in ADHD...
  48. ncbi request reprint Measuring anxiety: parent-child reporting differences in clinical samples
    Jose Barbosa
    Hospital for Sick Children, Toronto, University of Toronto, Toronto, Canada
    Depress Anxiety 15:61-5. 2002
    ..Such measures can be useful in monitoring clinical progress, however, provided parent and child reports are examined separately...
  49. ncbi request reprint Investigation of the G protein subunit Galphaolf gene (GNAL) in attention deficit/hyperactivity disorder
    Nancy Laurin
    Cell and Molecular Biology Division, Toronto Western Research Institute, University Health Network, Toronto, Ont, Canada
    J Psychiatr Res 42:117-24. 2008
    ..005) and rs8098539A (P=0.035). These preliminary findings suggest a possible contribution of GNAL in the susceptibility to ADHD, with possible involvement of parent-of-origin effects...
  50. ncbi request reprint Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes
    F Xavier Castellanos
    New York University Child Study Center, 577 First Avenue, CSC 204, New York, New York 10016 6404, USA
    Nat Rev Neurosci 3:617-28. 2002
  51. ncbi request reprint The serotonin receptor HTR1B: gene polymorphisms in attention deficit hyperactivity disorder
    Abel Ickowicz
    The Hospital for Sick Children, Toronto, Ontario, Canada
    Am J Med Genet B Neuropsychiatr Genet 144:121-5. 2007
    ..In addition we did not find evidence to suggest an association between HTR1B and perfectionism in this sample of ADHD families...
  52. ncbi request reprint Listening comprehension and working memory are impaired in attention-deficit hyperactivity disorder irrespective of language impairment
    Alison McInnes
    Brain and Behaviour Research Program, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Abnorm Child Psychol 31:427-43. 2003
    ..Findings that children with ADHD but no LI showed subtle higher-level listening comprehension deficits have implications for both current diagnostic practices and conceptualizations of ADHD...
  53. ncbi request reprint Executive function and ADHD: a comparison of children's performance during neuropsychological testing and real-world activities
    Vivienne Lawrence
    Graduate School of Psychology, University of Western Australia
    J Atten Disord 7:137-49. 2004
    ..This study compared children's performance on both neuropsychological and real-life measures of executive function and processing speed...
  54. ncbi request reprint Replication test for association of the IL-1 receptor antagonist gene, IL1RN, with attention-deficit/hyperactivity disorder
    Virginia L Misener
    Cell and Molecular Biology Division, Toronto Western Research Institute, University Health Network, Toronto, Ont, Canada
    Neuropsychobiology 50:231-4. 2004
    ..e. false-positive) result. These findings highlight the need for further investigations of this marker, in additional independent ADHD samples, in the future...
  55. ncbi request reprint Inconsistency in reaction time across the life span
    Benjamin R Williams
    Department of Psychology, University of Victoria, Victoria, BC, Canada
    Neuropsychology 19:88-96. 2005
    ..The findings highlight the importance of considering moment-to-moment changes in performance in psychological research...
  56. ncbi request reprint Whither causal models in the neuroscience of ADHD?
    Dave Coghill
    Department of Psychiatry, University of Dundee, Ninewella Hospital and Medical School, Dundee, DD1 9SY, Scotland, UK
    Dev Sci 8:105-14. 2005
    ....
  57. ncbi request reprint A meta-analysis of working memory impairments in children with attention-deficit/hyperactivity disorder
    Rhonda Martinussen
    Institute of Medical Science, University of Toronto, Toronto, Canada
    J Am Acad Child Adolesc Psychiatry 44:377-84. 2005
    ..To determine the empirical evidence for deficits in working memory (WM) processes in children and adolescents with attention-deficit/hyperactivity disorder (ADHD)...
  58. ncbi request reprint Inhibition of motor responses in siblings concordant and discordant for attention deficit hyperactivity disorder
    Russell J Schachar
    Department of Psychiatry, The Hospital for Sick Children, University of Toronto, Toronto M5N 2L1, Canada
    Am J Psychiatry 162:1076-82. 2005
    ..The authors sought to determine whether nonaffected siblings of ADHD probands have a motor response inhibition deficit and to assess concordance for this inhibition deficit in ADHD-concordant and ADHD-discordant sibling pairs...
  59. ncbi request reprint A randomized, placebo-controlled study of once-daily atomoxetine in the school setting in children with ADHD
    Margaret Weiss
    University of British Columbia, Vancouver, Canada
    J Am Acad Child Adolesc Psychiatry 44:647-55. 2005
    ..The primary objective of this clinical trial was to assess the efficacy of once-daily atomoxetine compared with placebo using teacher reports...
  60. ncbi request reprint Sequence variation in the 3'-untranslated region of the dopamine transporter gene and attention-deficit hyperactivity disorder (ADHD)
    Yu Feng
    Cell and Molecular Biology Division, Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    Am J Med Genet B Neuropsychiatr Genet 139:1-6. 2005
    ..Our results therefore refute the possibility of the reported DraI variation or alleles of the VNTR as the functional variants contributing to the disorder...
  61. ncbi request reprint Reading comprehension and reading related abilities in adolescents with reading disabilities and attention-deficit/hyperactivity disorder
    Karen Ghelani
    Ontario Institute for Studies in Education, The University of Toronto, Toronto, Canada
    Dyslexia 10:364-84. 2004
    ..Implications for reading interventions are outlined, as well as the clinical relevance for diagnosis...
  62. ncbi request reprint Time perception: modality and duration effects in attention-deficit/hyperactivity disorder (ADHD)
    Maggie E Toplak
    Brain and Behaviour Research Program, Research Institute of the Hospital for Sick Children, Ontario, Canada
    J Abnorm Child Psychol 33:639-54. 2005
    ..These group differences suggest impairments in basic timing mechanisms in ADHD...
  63. ncbi request reprint Temporal information processing in ADHD: findings to date and new methods
    Maggie E Toplak
    Brain and Behaviour Research Program, Research Institute, The Hospital for Sick Children, Toronto, Ont, Canada
    J Neurosci Methods 151:15-29. 2006
    ..This approach can lay the groundwork to provide a more precise understanding of neural network activity during different aspects and stages of temporal information processing in ADHD...
  64. ncbi request reprint Characterizing cognition in ADHD: beyond executive dysfunction
    F Xavier Castellanos
    Institute for Pediatric Neuroscience, NYU Child Study Center, 215 Lexington Avenue, New York, NY 10016, USA
    Trends Cogn Sci 10:117-23. 2006
    ..Such a reconceptualization provides a means to transcend the limits of current models of executive dysfunction in ADHD and suggests a plan for future research on cognition grounded in neurophysiological and developmental considerations...
  65. ncbi request reprint Colour perception in ADHD
    Tobias Banaschewski
    Child and Adolescent Psychiatry, University of Gottingen, Germany
    J Child Psychol Psychiatry 47:568-72. 2006
    ..However, the latter deficit was accounted for similarly by blue-yellow and red-green discrimination abilities. Blue-yellow colour perception problems in ADHD contribute to but do not fully explain the observed slowed colour naming...
  66. ncbi request reprint Working memory impairments in children with attention-deficit hyperactivity disorder with and without comorbid language learning disorders
    Rhonda Martinussen
    Institute of Medical Science, University of Toronto, Canada
    J Clin Exp Neuropsychol 28:1073-94. 2006
    ..The dimensional results are also consistent with prior research demonstrating the neuropsychological impairments are more strongly associated with the inattention symptom dimension than with the hyperactive-impulsive dimension...
  67. ncbi request reprint Gene for the serotonin transporter and ADHD: no association with two functional polymorphisms
    Karen G Wigg
    Department of Psychiatry, Cell and Molecular Division, The Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
    Am J Med Genet B Neuropsychiatr Genet 141:566-70. 2006
    ..These polymorphisms were genotyped in 209 ADHD families identified through an affected proband. We did not find evidence for an association of these polymorphisms, or haplotypes of these polymorphisms, to ADHD in this sample...
  68. ncbi request reprint Characterizing selective mutism: is it more than social anxiety?
    Katharina Manassis
    Department of Psychiatry, Hospital for Sick Children, Toronto, Ontario, Canada
    Depress Anxiety 18:153-61. 2003
    ....

Research Grants1

  1. Intervention for ADHD plus dyslexia: development project
    Rosemary Tannock; Fiscal Year: 2004
    ....