Research Topics
| Joanne RovetSummaryAffiliation: The Hospital for Sick Children Country: Canada Publications
| Collaborators
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Detail Information
Publications
Congenital hypothyroidism: a review of current diagnostic and treatment practices in relation to neuropsychologic outcomeJoanne Rovet
Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada
Paediatr Drugs 5:141-9. 2003....- Dissociating attention deficits in children with ADHD and congenital hypothyroidism using multiple CPTsJ F Rovet
Brain and Behaviour Program, The Hospital for Sick Children, Toronto, Ontario, Canada
J Child Psychol Psychiatry 42:1049-56. 2001..These results therefore signify the utility of these tasks in identifying the different mechanisms underlying the specific attention deficits of different groups of children... 
The role of transient hypothyroxinemia of prematurity in development of visual abilitiesJoanne Rovet
Department of Psychology, University of Toronto, Toronto, Ontario, Canada
Semin Perinatol 32:431-7. 2008..These findings therefore suggest that thyroid hormone is necessary for the development of early visual abilities and that THOP may partially explain the visual deficits of preterm infants...- Congenital hypothyroidism: an analysis of persisting deficits and associated factorsJoanne F Rovet
Department of Pediatrics, The University of Toronto Brain and Behaviour Program, The Hospital for Sick Children, Toronto, Ont, Canada
Child Neuropsychol 8:150-62. 2002..Because these four disabilities implicate different neural substrates, the findings described presently will provide insights as to the specific time windows when different brain structures in the human critically need thyroid hormone... - Children with congenital hypothyroidism and their siblings: do they really differ?Joanne F Rovet
Department of Pediatrics, Brain and Behavior Program, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Pediatrics 115:e52-7. 2005..The purpose of this study was to compare the results of children with CH and their unaffected siblings at the same age and with the same test... - Visual development of human milk-fed preterm infants provided with extra energy and nutrients after hospital dischargeDeborah L O'Connor
Physiology and Experimental Medicine Program, The Hospital for Sick Children, Toronto, Canada
JPEN J Parenter Enteral Nutr 36:349-53. 2012..Visual development was used in this study as a surrogate marker for neurodevelopment... - Long-term neurodevelopment of children exposed to maternal nausea and vomiting of pregnancy and diclectinIrena Nulman
Department of Clinical Pharmacology, Hospital for Sick Children, Toronto, Ontario, Canada
J Pediatr 155:45-50, 50.e1-2. 2009..To determine the effects of nausea and vomiting of pregnancy (NVP) and its treatment with diclectin on child neurodevelopment... - Growth and body composition of human milk-fed premature infants provided with extra energy and nutrients early after hospital discharge: 1-year follow-upAshley Aimone
Physiology and Experimental Medicine Program and the Department of Clinical Dietetics, Hospital for Sick Children, and Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
J Pediatr Gastroenterol Nutr 49:456-66. 2009..Data are also presented on general developmental level at 18-month corrected age (CA)... - Impact of neonatal thyroid hormone insufficiency and medical morbidity on infant neurodevelopment and attention following preterm birthNevena Simic
Department of Psychology, University of Toronto, Toronto, Ontario, Canada
Thyroid 19:395-401. 2009..The objective of this study was to examine the effects of reduced thyroid hormone levels on general neurodevelopment and attention at 3 months corrected age... - Social cognitive and emotion processing abilities of children with fetal alcohol spectrum disorders: a comparison with attention deficit hyperactivity disorderRachel L Greenbaum
Children s Mental Health Team, Surrey Place Centre, Toronto, Ontario, Canada
Alcohol Clin Exp Res 33:1656-70. 2009..However, these groups have not been directly compared for social problems or social cognition, nor has social cognition been directly examined in FASDs... - Development of contrast sensitivity in infants with prenatal and neonatal thyroid hormone insufficienciesGiuseppe Mirabella
Department of Ophthalmology and Vision Science, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada
Pediatr Res 57:902-7. 2005..05). There were no significant effects involving the preterm group. These results indicate that thyroid hormone is important for human visual development... - Understanding fetal alcohol spectrum disorders (FASDs): toward identification of a behavioral phenotypeKelly Nash
The Hospital for Sick Children, Toronto and the Ontario Institute for Studies in Education, University of Toronto, Toronto, Canada
ScientificWorldJournal 8:873-82. 2008..We conclude that future research initiatives comparing children with FASDs to nonalcohol-exposed children with similar cognitive and socioemotional profiles should aid in uncovering the unique behavioral phenotype for FASDs... - Visuospatial associative memory and hippocampal functioning in congenital hypothyroidismSarah M Wheeler
Neuroscience and Mental Health Research Program, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
J Int Neuropsychol Soc 18:49-56. 2012..These results suggest that perinatal deprivation of thyroid hormone has longstanding effects on hippocampal function and may account for memory problems experienced by adolescents with congenital hypothyroidism... - A differential approach for examining the behavioural phenotype of fetal alcohol spectrum disordersKelly Nash
Neuroscience and Mental Health program, The Hospital for Sick Children, Toronto, Ontario
J Popul Ther Clin Pharmacol 18:e440-53. 2011..Since many of the items referred to features of Oppositional Defiant/Conduct Disorder (ODD/CD), it was not clear whether the items reflected comorbidity with ODD/CD, or were unique to children with FASD... - Visual abilities at 6 months in preterm infants: impact of thyroid hormone deficiency and neonatal medical morbidityNevena Simic
Department of Psychology, University of Toronto, Toronto, Canada
Thyroid 20:309-15. 2010..To determine the interrelationship between these factors, we measured TH levels in the period ex utero and compared their visual abilities with those of term infants at 6 months (corrected) of age... - Effects of prenatal alcohol exposure on hippocampal volume, verbal learning, and verbal and spatial recall in late childhoodKaren A Willoughby
Neuroscience and Mental Health Research Program, Hospital for Sick Children, Toronto, Ontario, Canada
J Int Neuropsychol Soc 14:1022-33. 2008.... - Social problem solving in children with fetal alcohol spectrum disordersSara A Stevens
Department of Psychology, University of Toronto, and Neuroscience and Mental Health Program, The Hospital for Sick Children, Toronto
J Popul Ther Clin Pharmacol 19:e99-110. 2012..However, the factors underlying these impairments are poorly understood. Recent evidence has shown that social problem solving is a critical component of effective social functioning... - The relations between white matter and declarative memory in older children and adolescentsDonald J Mabbott
Program in Neuroscience and Mental Health, Research Institute, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
Brain Res 1294:80-90. 2009..Our findings support the role of white matter in facilitating connectivity between cerebral regions important for declarative memory... - Growth and nutrient intakes of human milk-fed preterm infants provided with extra energy and nutrients after hospital dischargeDeborah L O'Connor
Department of Clinical Dietetics, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario, Canada M5G 1X8
Pediatrics 121:766-76. 2008..We also assessed the impact of this intervention on the exclusivity of human milk feeding... - Assessment of visual functions following prenatal exposure to organic solventsChristine Till
The Motherisk Program, The Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada
Neurotoxicology 24:725-31. 2003..5-year-old boy following prenatal exposure to perchloroethylene (PCE). These VEP techniques therefore appear promising for the clinical assessment of visual toxicity in pediatric populations... - Agreement between prospective and retrospective reports of maternal exposure to chemicals during pregnancyChristine Till
Department of Psychology, University of Toronto, Toronto, Ontario, Canada
J Occup Environ Med 44:708-13. 2002..These variations in self-reports are of concern because they can severely affect estimates of human teratological risk... - Neurodevelopment of children following prenatal exposure to venlafaxine, selective serotonin reuptake inhibitors, or untreated maternal depressionIrena Nulman
Motherisk Program, Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, University of Toronto, Canada
Am J Psychiatry 169:1165-74. 2012..The authors compared the effects of prenatal exposure to venlafaxine (serotonin-norepinephrine reuptake inhibitor), selective serotonin reuptake inhibitors (SSRIs), and maternal depression... - Vision abnormalities in young children exposed prenatally to organic solventsChristine Till
Toronto Rehabilitation Institute, Toronto, Ont, Canada M5G 2A2
Neurotoxicology 26:599-613. 2005..Increasing levels of exposure may lead to further visual deficits affecting grating acuity. These findings support the need for a re-evaluation of current occupational exposure standards for pregnant women... - Novel approaches to the diagnosis of fetal alcohol spectrum disorderDaniela L Caprara
Division of Clinical Pharmacology Toxicology and Motherisk Program, The Hospital for Sick Children and University of Toronto, 555 University Avenue, Toronto, Ont, Canada M5G 1X8
Neurosci Biobehav Rev 31:254-60. 2007.... 
Meeting report: measuring endocrine-sensitive endpoints within the first years of lifeTye E Arbuckle
Biostatistics and Epidemiology Division, Health Canada, Ottawa, Ontario, Canada
Environ Health Perspect 116:948-51. 2008....- Child neurodevelopmental outcome and maternal occupational exposure to solventsDionne Laslo-Baker
Motherisk Program and Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, Ontario, Canada
Arch Pediatr Adolesc Med 158:956-61. 2004..Reducing exposure in pregnancy is merited until more refined risk assessment is possible. Further studies that address exposure to specific solvents, dose, and gestational timing of exposure are needed... - Turner syndrome: a review of genetic and hormonal influences on neuropsychological functioningJoanne Rovet
Department of Pediatrics and Psychology, University of Toronto, Toronto, Ont, Canada
Child Neuropsychol 10:262-79. 2004..Future research needs to identify the elemental processes that are disturbed in TS and map these both to events in early brain development and subsequent brain function and to specific gene and hormonal contributions... - Neurocognitive correlates of type 1 diabetes mellitus in childhoodMary Desrocher
Department of Psychology, York University, Toronto, Ontario, Canada
Child Neuropsychol 10:36-52. 2004..These findings are not without controversy, and limitations to conclusions will also be presented. Where relevant, recommendations for future research directions will be provided... - Hippocampal size and memory functioning in children and adolescents with congenital hypothyroidismSarah M Wheeler
The Hospital for Sick Children, Toronto, Ontario, Canada
J Clin Endocrinol Metab 96:E1427-34. 2011..One area of particular weakness is memory, especially on tasks known to be mediated by the hippocampus. However, the hippocampus has not been directly studied in this population... - Word and face recognition in children with congenital hypothyroidism: an event-related potential studySandra L Hepworth
Department of Psychology, University of Toronto, ON, Canada
J Clin Exp Neuropsychol 28:509-27. 2006..It is proposed that the dampened neurophysiological response to repeated verbal stimuli by children with CH may explain some of their clinically observed difficulties in short-term recognition memory... - Workplace standards for exposure to toxicants during pregnancyChristine Till
Department of Psychology, York University, Toronto, ON
Can J Public Health 99:472-4. 2008..Management options that can be implemented early to provide added protection when a hazard cannot be reduced or eliminated are recommended... - Iodine supplementation for pregnancy and lactation-United States and Canada: recommendations of the American Thyroid AssociationDavid V Becker
Thyroid 16:949-51. 2006.... - In search of the optimal therapy for congenital hypothyroidismJoanne F Rovet
J Pediatr 144:698-700. 2004