Paul Craig Nathan

Summary

Affiliation: The Hospital for Sick Children
Country: Canada

Publications

  1. ncbi The prevalence of overweight and obesity in pediatric survivors of cancer
    Paul C Nathan
    Division of Haematology Oncology, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr 149:518-25. 2006
  2. ncbi Childhood cancer survivorship educational resources in North American pediatric hematology/oncology fellowship training programs: a survey study
    Paul C Nathan
    The Hospital for Sick Children, Toronto, ON, Canada
    Pediatr Blood Cancer 57:1186-90. 2011
  3. ncbi Health-related quality of life in adult survivors of childhood Wilms tumor or neuroblastoma: A report from the childhood cancer survivor study
    Paul C Nathan
    The Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Blood Cancer 49:704-15. 2007
  4. ncbi Guidelines for identification of, advocacy for, and intervention in neurocognitive problems in survivors of childhood cancer: a report from the Children's Oncology Group
    Paul C Nathan
    Division of Haematology Oncology, The Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8, Canada
    Arch Pediatr Adolesc Med 161:798-806. 2007
  5. ncbi Medical care in long-term survivors of childhood cancer: a report from the childhood cancer survivor study
    Paul C Nathan
    Division of Haematology Oncology, Hospital for Sick Children, Toronto, ON, Canada
    J Clin Oncol 26:4401-9. 2008
  6. ncbi A pilot study of ondansetron plus metopimazine vs. ondansetron monotherapy in children receiving highly emetogenic chemotherapy: a Bayesian randomized serial N-of-1 trials design
    P C Nathan
    Division of Haematology Oncology, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada
    Support Care Cancer 14:268-76. 2006
  7. ncbi Long-term outcomes in survivors of childhood acute lymphoblastic leukemia
    Paul C Nathan
    Division of Hematology Oncology, Department of Paediatrics, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada
    Hematol Oncol Clin North Am 23:1065-82, vi-vii. 2009
  8. ncbi Screening and surveillance for second malignant neoplasms in adult survivors of childhood cancer: a report from the childhood cancer survivor study
    Paul Craig Nathan
    Hospital for Sick Children, Toronto, Ontario, Canada, USA
    Ann Intern Med 153:442-51. 2010
  9. ncbi Critical issues in transition and survivorship for adolescents and young adults with cancers
    Paul C Nathan
    The Hospital for Sick Children, Toronto, Ontario, Canada
    Cancer 117:2335-41. 2011
  10. ncbi Health behaviors, medical care, and interventions to promote healthy living in the Childhood Cancer Survivor Study cohort
    Paul C Nathan
    Hospital for Sick Children, Ontario, Canada
    J Clin Oncol 27:2363-73. 2009

Detail Information

Publications31

  1. ncbi The prevalence of overweight and obesity in pediatric survivors of cancer
    Paul C Nathan
    Division of Haematology Oncology, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr 149:518-25. 2006
    ..To compare the prevalence of overweight in a cohort of pediatric survivors of cancer with that in the general population...
  2. ncbi Childhood cancer survivorship educational resources in North American pediatric hematology/oncology fellowship training programs: a survey study
    Paul C Nathan
    The Hospital for Sick Children, Toronto, ON, Canada
    Pediatr Blood Cancer 57:1186-90. 2011
    ..We surveyed North American pediatric hematology/oncology training programs to evaluate their resources and capacity for educating medical trainees about survivorship...
  3. ncbi Health-related quality of life in adult survivors of childhood Wilms tumor or neuroblastoma: A report from the childhood cancer survivor study
    Paul C Nathan
    The Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Blood Cancer 49:704-15. 2007
    ..Long-term survivors of Wilms tumor and neuroblastoma may experience significant late adverse effects from their disease and its therapy. Little is known, however, about the health-related quality of life experienced by these survivors...
  4. ncbi Guidelines for identification of, advocacy for, and intervention in neurocognitive problems in survivors of childhood cancer: a report from the Children's Oncology Group
    Paul C Nathan
    Division of Haematology Oncology, The Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8, Canada
    Arch Pediatr Adolesc Med 161:798-806. 2007
    ..Finally, we list resources that can guide patients, their parents, and their medical caregivers as they face the long-term neurocognitive consequences of cancer therapy...
  5. ncbi Medical care in long-term survivors of childhood cancer: a report from the childhood cancer survivor study
    Paul C Nathan
    Division of Haematology Oncology, Hospital for Sick Children, Toronto, ON, Canada
    J Clin Oncol 26:4401-9. 2008
    ..To evaluate whether childhood cancer survivors receive regular medical care focused on the specific morbidities that can arise from their therapy...
  6. ncbi A pilot study of ondansetron plus metopimazine vs. ondansetron monotherapy in children receiving highly emetogenic chemotherapy: a Bayesian randomized serial N-of-1 trials design
    P C Nathan
    Division of Haematology Oncology, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada
    Support Care Cancer 14:268-76. 2006
    ..The present study was designed to assess its efficacy in children with cancer, a group in which it has not been studied previously...
  7. ncbi Long-term outcomes in survivors of childhood acute lymphoblastic leukemia
    Paul C Nathan
    Division of Hematology Oncology, Department of Paediatrics, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada
    Hematol Oncol Clin North Am 23:1065-82, vi-vii. 2009
    ....
  8. ncbi Screening and surveillance for second malignant neoplasms in adult survivors of childhood cancer: a report from the childhood cancer survivor study
    Paul Craig Nathan
    Hospital for Sick Children, Toronto, Ontario, Canada, USA
    Ann Intern Med 153:442-51. 2010
    ..Survivors of childhood cancer may develop a second malignant neoplasm during adulthood and therefore require regular surveillance...
  9. ncbi Critical issues in transition and survivorship for adolescents and young adults with cancers
    Paul C Nathan
    The Hospital for Sick Children, Toronto, Ontario, Canada
    Cancer 117:2335-41. 2011
    ..The limitations in cancer center resources (along with survivor preference) strongly suggest that the long-term care of survivors will need to be shared between the cancer centers and primary care providers in survivors' communities...
  10. ncbi Health behaviors, medical care, and interventions to promote healthy living in the Childhood Cancer Survivor Study cohort
    Paul C Nathan
    Hospital for Sick Children, Ontario, Canada
    J Clin Oncol 27:2363-73. 2009
    ..Despite their long-term risks, many survivors of childhood cancer engage in risky health behaviors and do not receive adequate risk-based medical care...
  11. ncbi Optimizing emetic control in children receiving antineoplastic therapy: beyond the guidelines
    L Lee Dupuis
    Department of Pharmacy, The Hospital for Sick Children, Toronto, Ontario, Canada
    Paediatr Drugs 12:51-61. 2010
    ....
  12. ncbi A cross Canada survey of sperm banking practices in pediatric oncology centers
    Amy Lee Chong
    The Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Blood Cancer 55:1356-61. 2010
    ..Sperm banking is an established fertility preservation option in pubertal males. We sought to describe current practices in Canadian pediatric oncology programs, and to identify perceived barriers to sperm banking for male adolescents...
  13. ncbi Meta-analysis: effect of prophylactic hematopoietic colony-stimulating factors on mortality and outcomes of infection
    Lillian Sung
    Division of Haematology Oncology, The University of Toronto, The Hospital for Sick Children, and University Health Network, Toronto, Ontario, Canada
    Ann Intern Med 147:400-11. 2007
    ..Benefits of prophylactic hematopoietic colony-stimulating factors (CSFs) in adults and children receiving cancer chemotherapy or undergoing stem-cell transplantation (SCT) are unclear...
  14. ncbi Options for the prevention and management of acute chemotherapy-induced nausea and vomiting in children
    L Lee Dupuis
    Department of Pharmacy, Division of Haematology Oncology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Paediatr Drugs 5:597-613. 2003
    ..Complementary interventions such as acupuncture, hypnosis, counseling, or ginger may also be of benefit. Further study is required to establish optimal antiemetic strategies in children...
  15. ncbi Corticosteroids versus intravenous immune globulin for the treatment of acute immune thrombocytopenic purpura in children: a systematic review and meta-analysis of randomized controlled trials
    Carolyn E Beck
    Division of Paediatric Medicine, The Hospital for Sick Children, and the University of Toronto, Toronto, Ontario, Canada
    J Pediatr 147:521-7. 2005
    ..To compare the effectiveness of corticosteroids with intravenous immune globulin (IVIG) for the initial treatment of children with acute immune thrombocytopenic purpura (ITP)...
  16. ncbi Comparison of long-term neurocognitive outcomes in young children with acute lymphoblastic leukemia treated with cranial radiation or high-dose or very high-dose intravenous methotrexate
    Brenda J Spiegler
    Department of Paediatrics, Division of Haematology Oncology, The Hospital for Sick Children, The University of Toronto, Toronto, Ontario, Canada
    J Clin Oncol 24:3858-64. 2006
    ..The impact of chemotherapy-only protocols on neurocognitive outcomes is unclear, and the importance of systemic MTX dose has not been established...
  17. ncbi Association of the t(12;22)(q13;q12) EWS/ATF1 rearrangement with polyphenotypic round cell sarcoma of bone: a case report
    Gino R Somers
    Department of Paediatric Laboratory Medicine, Hospital for Sick Children, Toronto, Ontario, Canada
    Am J Surg Pathol 29:1673-9. 2005
    ..However, given the lack of morphologic features usually present in CCS, a diagnosis of polyphenotypic round cell sarcoma was made. This tumor thus expands the spectrum of neoplasms associated with the t(12;22)(q13;q12) rearrangement...
  18. ncbi CNS-directed therapy in young children with T-lineage acute lymphoblastic leukemia: High-dose methotrexate versus cranial irradiation
    Paul C Nathan
    Department of Paediatrics, Division of Haematology/Oncology, The Hospital for Sick Children Research Institute, The University of Toronto, Toronto, Ontario, Canada
    Pediatr Blood Cancer 42:24-9. 2004
    ..CONCLUSIONS: The use of HD-MTX instead of CRT as CNS-directed therapy in very young children with T-ALL does not compromise survival, while avoiding the adverse long-term effects of cranial irradiation...
  19. ncbi Prophylactic granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor decrease febrile neutropenia after chemotherapy in children with cancer: a meta-analysis of randomized controlled trials
    Lillian Sung
    Department of Pediatrics, University of Toronto, Ontario, Canada
    J Clin Oncol 22:3350-6. 2004
    ....
  20. ncbi Consolidation therapy with autologous bone marrow transplantation in adults with acute myeloid leukemia: a meta-analysis
    Paul C Nathan
    Department of Paediatrics, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Natl Cancer Inst 96:38-45. 2004
    ..01, 95% CI = 0.89 to 1.15; P =.86). CONCLUSION: Our results do not support the routine use of autologous bone marrow transplantation in adult acute myeloid leukemia patients in first remission...
  21. ncbi Unusual reactions to 5-HT3 receptor antagonists in a child with rhabdomyosarcoma
    Candace Y W Lee
    Division of Clinical Pharmacology and Toxicology, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada
    Can J Clin Pharmacol 17:e1-4. 2010
    ..Potential mechanisms for these reactions are discussed...
  22. ncbi Toxicity and outcome of children with treatment related acute myeloid leukemia
    Uri Tabori
    Departments of Hematology Oncology and Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Canada
    Pediatr Blood Cancer 50:17-23. 2008
    ..The aim of this study was to evaluate the clinical course and outcome of children with treatment related acute myeloid leukemia (tAML) and compare them to children with primary AML (pAML)...
  23. ncbi Survival and late effects in children with Hodgkin's lymphoma treated with MOPP/ABV and low-dose, extended-field irradiation
    Lionel M L Chow
    Division of Haematology and Oncology, Department of Paediatrics, Toronto Sunnybrook Regional Cancer Centre, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Clin Oncol 24:5735-41. 2006
    ....
  24. ncbi Twenty years of follow-up among survivors of childhood and young adult acute myeloid leukemia: a report from the Childhood Cancer Survivor Study
    Daniel A Mulrooney
    Department of Pediatrics, University of Minnesota Medical School and Cancer Center, Minneapolis, MN 55455, USA
    Cancer 112:2071-9. 2008
    ..Limited data exist on the comprehensive assessment of late medical and social effects experienced by survivors of childhood and young adult acute myeloid leukemia (AML)...
  25. ncbi Challenges after curative treatment for childhood cancer and long-term follow up of survivors
    Kevin C Oeffinger
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Pediatr Clin North Am 55:251-73, xiii. 2008
    ....
  26. ncbi The impact of limitations in physical, executive, and emotional function on health-related quality of life among adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
    Kirsten K Ness
    Department of Epidemiology and Cancer Control, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Arch Phys Med Rehabil 89:128-36. 2008
    ....
  27. ncbi Treatment late effects in long-term survivors of pediatric sarcoma
    Patrick Mansky
    Division of Intramural Research, National Center for Complementary and Alternative Medicine, National Institutes of Health, DHHS, Bethesda, Maryland 20892, USA
    Pediatr Blood Cancer 48:192-9. 2007
    ..To assess health and musculoskeletal function in survivors of pediatric sarcomas...
  28. ncbi Successful treatment of life-threatening generalized infantile myofibromatosis using low-dose chemotherapy
    Minal M Gandhi
    Department of Haematology/Oncology, Great Ormond Street Hospital for Sick Children NHS Trust, London, United Kingdom
    J Pediatr Hematol Oncol 25:750-4. 2003
    ..The authors propose a prospective international trial using a safe low-dose chemotherapy protocol to test the efficacy of this treatment strategy...
  29. ncbi Very high-dose methotrexate (33.6 g/m(2)) as central nervous system preventive therapy for childhood acute lymphoblastic leukemia: results of National Cancer Institute/Children's Cancer Group trials CCG-191P, CCG-134P and CCG-144P
    Paul C Nathan
    Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Leuk Lymphoma 47:2488-504. 2006
    ..VHD-MTX achieved similar survival to other CNS-directed therapies without the long-term impact on intelligence, but with substantial acute toxicities...
  30. ncbi Adjuvant chemotherapy for the treatment of advanced pediatric nonrhabdomyosarcoma soft tissue sarcoma: the National Cancer Institute experience
    Paul C Nathan
    National Cancer Institute, Pediatric Oncology Branch, Bethesda, MD 20892, USA
    Pediatr Blood Cancer 44:449-54. 2005
    ..Prospective randomized trials are needed to quantify the contribution of chemotherapy and to determine the ideal regimen...
  31. ncbi Challenges to the measurement of health-related quality of life in children receiving cancer therapy
    Paul C Nathan
    National Cancer Institute, Pediatric Oncology Branch, Bethesda, Maryland, USA
    Pediatr Blood Cancer 43:215-23. 2004
    ....