Binita M Kamath

Summary

Affiliation: The Hospital for Sick Children
Country: Canada

Publications

  1. doi request reprint Renal anomalies in Alagille syndrome: a disease-defining feature
    Binita M Kamath
    Division of Gastroenterology, Hepatology and Nutrition at The Hospital for Sick Children, Toronto, Ontario, Canada
    Am J Med Genet A 158:85-9. 2012
  2. pmc Pancreatic insufficiency is not a prevalent problem in Alagille syndrome
    Binita M Kamath
    Hospital for Sick Children, Toronto, Canada
    J Pediatr Gastroenterol Nutr 55:612-4. 2012
  3. doi request reprint Outcomes of liver transplantation for patients with Alagille syndrome: the studies of pediatric liver transplantation experience
    Binita M Kamath
    Division of Gastroenterology, Hepatology, and Nutrition, Hospital for Sick Children, Toronto, Canada
    Liver Transpl 18:940-8. 2012
  4. ncbi request reprint Medical management of Alagille syndrome
    Binita M Kamath
    Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Gastroenterol Nutr 50:580-6. 2010
  5. pmc A longitudinal study to identify laboratory predictors of liver disease outcome in Alagille syndrome
    Binita M Kamath
    Division of Gastroenterology, Children s Hospital of Philadelphia, USA
    J Pediatr Gastroenterol Nutr 50:526-30. 2010
  6. doi request reprint Liver transplantation in children: update 2010
    Binita M Kamath
    Department of Pediatrics, University of Toronto, Toronto, ON M5S 1A1, Canada
    Pediatr Clin North Am 57:401-14, table of contents. 2010
  7. pmc Genomic alterations in biliary atresia suggest region of potential disease susceptibility in 2q37.3
    Melissa Leyva-Vega
    Division of Gastroenterology, Hepatology and Nutrition, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Am J Med Genet A 152:886-95. 2010
  8. pmc Alagille syndrome in a Vietnamese cohort: mutation analysis and assessment of facial features
    Henry C Lin
    Division of Gastroenterology, Hepatology, and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Am J Med Genet A 158:1005-13. 2012
  9. pmc SNP array mapping of chromosome 20p deletions: genotypes, phenotypes, and copy number variation
    Binita M Kamath
    Division of Gastroenterology and Nutrition, Department of Pediatrics, The Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Hum Mutat 30:371-8. 2009
  10. doi request reprint Renal involvement and the role of Notch signalling in Alagille syndrome
    Binita M Kamath
    The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
    Nat Rev Nephrol 9:409-18. 2013

Collaborators

Detail Information

Publications14

  1. doi request reprint Renal anomalies in Alagille syndrome: a disease-defining feature
    Binita M Kamath
    Division of Gastroenterology, Hepatology and Nutrition at The Hospital for Sick Children, Toronto, Ontario, Canada
    Am J Med Genet A 158:85-9. 2012
    ..These data also suggest that renal involvement be considered the sixth defining criterion for ALGS...
  2. pmc Pancreatic insufficiency is not a prevalent problem in Alagille syndrome
    Binita M Kamath
    Hospital for Sick Children, Toronto, Canada
    J Pediatr Gastroenterol Nutr 55:612-4. 2012
    ..FE measurements were normal (>200  μg/g) in 40 (95%) and indeterminate (100-200  μg/g) in 2 (5%). As FE is the most reliable screen for PI, these data suggest that PI is not a prevalent problem in ALGS...
  3. doi request reprint Outcomes of liver transplantation for patients with Alagille syndrome: the studies of pediatric liver transplantation experience
    Binita M Kamath
    Division of Gastroenterology, Hepatology, and Nutrition, Hospital for Sick Children, Toronto, Canada
    Liver Transpl 18:940-8. 2012
    ..Although the 1-year survival rate was modestly lower for the ALGS patients versus the BA patients, the clustering of deaths within the first 30 days is notable and warrants increased vigilance and further investigation...
  4. ncbi request reprint Medical management of Alagille syndrome
    Binita M Kamath
    Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Gastroenterol Nutr 50:580-6. 2010
    ..Furthermore, the liver disease in particular requires an appreciation of the natural history and evolution of the profound cholestasis...
  5. pmc A longitudinal study to identify laboratory predictors of liver disease outcome in Alagille syndrome
    Binita M Kamath
    Division of Gastroenterology, Children s Hospital of Philadelphia, USA
    J Pediatr Gastroenterol Nutr 50:526-30. 2010
    ..This poses a challenge to the clinician in terms of timing therapies. The study aim was to identify laboratory markers present in children younger than 5 years that could predict the ultimate outcome of liver disease in AGS...
  6. doi request reprint Liver transplantation in children: update 2010
    Binita M Kamath
    Department of Pediatrics, University of Toronto, Toronto, ON M5S 1A1, Canada
    Pediatr Clin North Am 57:401-14, table of contents. 2010
    ..These issues require constant collaboration between pediatricians, transplant hepatologists, transplant surgeons, nurses, dieticians, social workers, psychologists, and other supporting services...
  7. pmc Genomic alterations in biliary atresia suggest region of potential disease susceptibility in 2q37.3
    Melissa Leyva-Vega
    Division of Gastroenterology, Hepatology and Nutrition, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Am J Med Genet A 152:886-95. 2010
    ..The overlapping 1.76 Mb deletion on chromosome 2q37.3 from 240,936,900 to 242,692,820 constitutes the critical region and the genes within this region could be candidates for susceptibility to BA...
  8. pmc Alagille syndrome in a Vietnamese cohort: mutation analysis and assessment of facial features
    Henry C Lin
    Division of Gastroenterology, Hepatology, and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Am J Med Genet A 158:1005-13. 2012
    ..This is the first report of mutations and phenotypic spectrum of ALGS in a Vietnamese population...
  9. pmc SNP array mapping of chromosome 20p deletions: genotypes, phenotypes, and copy number variation
    Binita M Kamath
    Division of Gastroenterology and Nutrition, Department of Pediatrics, The Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Hum Mutat 30:371-8. 2009
    ..Deletions of the short arm of chromosome 20 are associated with relatively mild and limited clinical anomalies. The use of SNP arrays provides accurate high-resolution definition of genomic abnormalities...
  10. doi request reprint Renal involvement and the role of Notch signalling in Alagille syndrome
    Binita M Kamath
    The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
    Nat Rev Nephrol 9:409-18. 2013
    ..Increased awareness of Alagille syndrome amongst nephrologists may lead to more diagnoses of Alagille syndrome in patients with apparently isolated renal disease...
  11. pmc Pathologic lower extremity fractures in children with Alagille syndrome
    Christina B Bales
    Department of Pediatrics, The Department of Biostatistics and Epidemiology at the University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Pediatr Gastroenterol Nutr 51:66-70. 2010
    ..In this retrospective study, we aimed to determine the incidence and distribution of fractures in patients with Alagille syndrome, 1 of the leading inherited causes of pediatric cholestatic liver disease...
  12. ncbi request reprint Intracranial vascular abnormalities in patients with Alagille syndrome
    Karan M Emerick
    Division of Gastroenterology, The Children s Memorial Hospital and Northwestern University Medical School, Chicago, Illinois 60614, USA
    J Pediatr Gastroenterol Nutr 41:99-107. 2005
    ....
  13. doi request reprint Alagille syndrome and liver transplantation
    Binita M Kamath
    Department of Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    J Pediatr Gastroenterol Nutr 50:11-5. 2010
    ....
  14. ncbi request reprint Glatiramer acetate-induced acute hepatotoxicity in an adolescent with MS
    Naila Makhani
    Hospital for Sick Children, Canada
    Neurology 81:850-2. 2013
    ..Here, we report GA-induced hepatotoxicity in a pediatric patient with multiple sclerosis (MS). ..