William B Hanley

Summary

Affiliation: The Hospital for Sick Children
Country: Canada

Publications

  1. ncbi request reprint Adult phenylketonuria
    W B Hanley
    Phenylketonuria Programme, Division of Clinical and Biochemical Genetics, Department of Pediatrics and the Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada
    Am J Med 117:590-5. 2004
  2. ncbi request reprint Maternal Phenylketonuria Collaborative Study (MPKUCS)--the 'outliers'
    W B Hanley
    PKU Programme, Hospital for Sick Children, Toronto, Ontario, Canada
    J Inherit Metab Dis 27:711-23. 2004
  3. doi request reprint Finding the fertile woman with phenylketonuria
    William B Hanley
    Division of Clinical and Biochemical Genetics, Department of Paediatrics, The Hospital for Sick Children and the University of Toronto, Faculty of Medicine, 555 University Avenue, Toronto, ON M5G 1X8, Canada
    Eur J Obstet Gynecol Reprod Biol 137:131-5. 2008
  4. pmc Randomised controlled trial of tyrosine supplementation on neuropsychological performance in phenylketonuria
    M L Smith
    Department of Psychology, University of Toronto, Mississauga, Ontario, Canada
    Arch Dis Child 78:116-21. 1998
  5. ncbi request reprint "Hypotyrosinemia" in phenylketonuria
    W B Hanley
    Division of Clinical and Biochemical Genetics, The Hospital for Sick Children, Toronto, Ontario, Canada
    Mol Genet Metab 69:286-94. 2000
  6. ncbi request reprint Impact of the phenylalanine hydroxylase gene on maternal phenylketonuria outcome
    Flemming Guttler
    Department of Inherited Metabolic Disease and Molecular Genetics, The John F Kennedy Institute, Glostrup, Denmark
    Pediatrics 112:1530-3. 2003
  7. ncbi request reprint Pregnancy experiences in the woman with mild hyperphenylalaninemia
    Harvey L Levy
    Division of Genetics, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    Pediatrics 112:1548-52. 2003
  8. ncbi request reprint Tetrahydrobiopterin and mild phenylketonuria
    William B Hanley
    N Engl J Med 348:1722-4; author reply 1722-4. 2003

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Adult phenylketonuria
    W B Hanley
    Phenylketonuria Programme, Division of Clinical and Biochemical Genetics, Department of Pediatrics and the Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada
    Am J Med 117:590-5. 2004
    ..New investigative methods and treatment options are on the horizon. There is an urgent need for physicians who will orchestrate the care of adults with phenylketonuria...
  2. ncbi request reprint Maternal Phenylketonuria Collaborative Study (MPKUCS)--the 'outliers'
    W B Hanley
    PKU Programme, Hospital for Sick Children, Toronto, Ontario, Canada
    J Inherit Metab Dis 27:711-23. 2004
    ..Not all offspring from the same (untreated) PKU mother may be similarly affected. Finding the source of these modifiers might effect the treatment of MPKU...
  3. doi request reprint Finding the fertile woman with phenylketonuria
    William B Hanley
    Division of Clinical and Biochemical Genetics, Department of Paediatrics, The Hospital for Sick Children and the University of Toronto, Faculty of Medicine, 555 University Avenue, Toronto, ON M5G 1X8, Canada
    Eur J Obstet Gynecol Reprod Biol 137:131-5. 2008
    ..quot;Selective Prenatal Screening or Case-Finding" for fertile women with PKU is recommended and a template is presented...
  4. pmc Randomised controlled trial of tyrosine supplementation on neuropsychological performance in phenylketonuria
    M L Smith
    Department of Psychology, University of Toronto, Mississauga, Ontario, Canada
    Arch Dis Child 78:116-21. 1998
    ..To test the efficacy of tyrosine supplementation, as an adjunct to dietary treatment, on neuropsychological test performance in individuals with phenylketonuria...
  5. ncbi request reprint "Hypotyrosinemia" in phenylketonuria
    W B Hanley
    Division of Clinical and Biochemical Genetics, The Hospital for Sick Children, Toronto, Ontario, Canada
    Mol Genet Metab 69:286-94. 2000
    ..8 micromol/L in infants, children, and adolescents in the literature review. Our data support the previously undocumented statements in the literature that plasma tyrosine levels are low in PKU...
  6. ncbi request reprint Impact of the phenylalanine hydroxylase gene on maternal phenylketonuria outcome
    Flemming Guttler
    Department of Inherited Metabolic Disease and Molecular Genetics, The John F Kennedy Institute, Glostrup, Denmark
    Pediatrics 112:1530-3. 2003
    ....
  7. ncbi request reprint Pregnancy experiences in the woman with mild hyperphenylalaninemia
    Harvey L Levy
    Division of Genetics, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    Pediatrics 112:1548-52. 2003
    ..A major issue in maternal phenylketonuria (MPKU) has been whether maternal non-PKU mild hyperphenylalaninemia (MHP) is teratogenic. Such untreated pregnancies and their outcomes are presented on this report...
  8. ncbi request reprint Tetrahydrobiopterin and mild phenylketonuria
    William B Hanley
    N Engl J Med 348:1722-4; author reply 1722-4. 2003