Research Topics
| Lars Grosse-WortmannSummaryAffiliation: The Hospital for Sick Children Country: Canada Publications
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Detail Information
Publications
Aortopulmonary collateral flow volume affects early postoperative outcome after Fontan completion: a multimodality studyLars Grosse-Wortmann
Labatt Family Heart Center, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
J Thorac Cardiovasc Surg 144:1329-36. 2012..However, the significance of aortopulmonary collateral flow for the postoperative outcome after total cavopulmonary connection is unclear and was sought to be determined...- Cardiopulmonary magnetic resonance imaging in children after lung transplantation: preliminary observationsLars Grosse-Wortmann
Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
J Heart Lung Transplant 30:1294-8. 2011..In this pilot study we aimed to assess the feasibility of magnetic resonance imaging (MRI) in 8 pediatric patients after lung transplantation... - Early changes in right ventricular function and their clinical consequences in childhood and adolescent dilated cardiomyopathyLars Grosse-Wortmann
The Labatt Family Heart Centre, Division of Cardiology, Department of Paediatrics, The Hospital for Sick Children, The University of Toronto, Toronto, Canada
Cardiol Young 20:418-25. 2010..Right ventricular size and ejection fraction may be important indicators of sub-clinical cardiac failure and we suggest monitoring them routinely in dilated cardiomyopathy... 
Prevalence of and risk factors for perioperative arrhythmias in neonates and children after cardiopulmonary bypass: continuous holter monitoring before and for three days after surgeryLars Grosse-Wortmann
Department of Paediatric Cardiology, Aachen University Hospital, Aachen, Germany
J Cardiothorac Surg 5:85. 2010....- Late gadolinium enhancement of the right ventricular myocardium: is it really different from the left ?Lars Grosse-Wortmann
Section of Cardiac Imaging, Department of Diagnostic Imaging, The Hospital for Sick Children, The University of Toronto, Toronto, Canada
J Cardiovasc Magn Reson 10:20. 2008..We conclude that sufficient spatial resolution is important for adequate late gadolinium enhancement of the right ventricle... - Impaired right and left ventricular diastolic myocardial mechanics and filling in asymptomatic children and adolescents after repair of tetralogy of FallotMark K Friedberg
Division of Paediatric Cardiology, The Labatt Family Heart Center, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada
Eur Heart J Cardiovasc Imaging 13:905-13. 2012..We hypothesized that children after TOF repair have diastolic dysfunction and dyssynchrony by this measure, and sought to determine their relationship with pulmonary regurgitation (PR), RV enlargement, and aerobic exercise capacity... - Feasibility of quantification of the distribution of blood flow in the normal human fetal circulation using CMR: a cross-sectional studyMike Seed
Department of Paediatrics, Division of Paediatric Cardiology, University of Toronto, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada
J Cardiovasc Magn Reson 14:79. 2012..These were obtained using a retrospective gating technique known as metric optimised gating (MOG)... - Impaired left ventricular myocardial mechanics and their relation to pulmonary regurgitation, right ventricular enlargement and exercise capacity in asymptomatic children after repair of tetralogy of FallotFernanda P Fernandes
Labatt Family Heart Centre, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada
J Am Soc Echocardiogr 25:494-503. 2012..The hypothesis was that impaired LV myocardial mechanics are related to pulmonary regurgitation, right ventricular (RV) enlargement, and exercise capacity... - Aortopulmonary collaterals after bidirectional cavopulmonary connection or Fontan completion: quantification with MRILars Grosse-Wortmann
The Labatt Family Heart Center and the Department of Diagnostic Imaging, The Hospital for Sick Children, The University of Toronto, Toronto, Ontario, Canada
Circ Cardiovasc Imaging 2:219-25. 2009..We aimed to quantify APC flow after bidirectional cavopulmonary connections and Fontan completions, using phase-contrast MRI, and to identify risk factors for the development of APCs... - Can simple echocardiographic measures reduce the number of cardiac magnetic resonance imaging studies to diagnose right ventricular enlargement in congenital heart disease?Mohammed H Alghamdi
Labatt Family Heart Centre, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada
J Am Soc Echocardiogr 25:518-23. 2012..The aim of this study was to investigate whether simple echocardiographic measurements can adequately predict RV volumes below clinical thresholds, thereby reducing the need for CMR in some patients... - Acute effects of the ACE inhibitor enalaprilat on the pulmonary, cerebral and systemic blood flow and resistance after the bidirectional cavopulmonary connectionKyong Jin Lee
The Labatt Family Heart Centre, Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto School of Medicine, Canada
Heart 97:1343-8. 2011..Angiotensin-converting enzyme inhibitors (ACEI) are often used in this complex circulation, but the effects of their vasodilation are unclear... - Phase-contrast magnetic resonance quantification of normal pulmonary venous returnHyun Woo Goo
Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
J Magn Reson Imaging 29:588-94. 2009..To assess the feasibility of phase-contrast magnetic resonance (PCMR) in quantifying the pulmonary venous return in normal subjects... - Relation of right ventricular mechanics to exercise tolerance in children after tetralogy of Fallot repairMark K Friedberg
Division of Paediatric Cardiology, The Labatt Family Heart Center, Hospital for Sick Children and University of Toronto, Toronto, Canada
Am Heart J 165:551-7. 2013..We investigated RV myocardial deformation and dyssynchrony in children after TOF repair and their association with exercise capacity... 
Massive systemic-to-pulmonary collateral arteries in the setting of a cavopulmonary shunt and pulmonary venous stenosisLars Grosse Wortmann
Section of Cardiac Imaging, Department of Diagnostic Imaging, The University of Toronto, Toronto, Canada
Cardiol Young 17:548-50. 2007..The reversal of flow in the left pulmonary artery was accentuated by flow through collateral arteries feeding the left lung. Within 14 months, the collateral flow increased six-fold, resulting in a doubling of the cardiac output...- Hybrid versus Norwood strategies for single-ventricle palliationKenji Baba
Division of Cardiovascular Surgery, The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Circulation 126:S123-31. 2012..Hybrid and Norwood strategies differ substantially in terms of stage II palliative procedures. We sought to compare these strategies with an emphasis on survival and reintervention after stage II and subsequent Fontan completion... - Influence of RV restrictive physiology on LV diastolic function in children after tetralogy of Fallot repairNauman Ahmad
The Labatt Family Heart Center, The Hospital for Sick Children, Toronto, Ontario, Canada
J Am Soc Echocardiogr 25:866-73. 2012..Via diastolic ventricular interaction, RV filling characteristics may influence left ventricular (LV) filling. The aim of this study was to analyze the effect of RV diastolic physiology on LV diastolic properties... - Echocardiographic assessment of right ventricular volumes after surgical repair of tetralogy of Fallot: clinical validation of a new echocardiographic methodAndreea Dragulescu
Division of Cardiology, The Labatt Family Heart Centre, Department of Paediatrics, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada
J Am Soc Echocardiogr 24:1191-8. 2011..The aim of this study was to assess the feasibility and reliability of this novel echocardiographic technique in patients after TOF repair. The accuracy of the method was assessed by comparison with measurements obtained by cardiac MRI... - Pulmonary vein flow pattern in children with bidirectional cavopulmonary connection or Fontan circuitMasoud Shariat
Department of Radiology, Hospital for Sick Children, 555 University Ave, Toronto, Canada
Pediatr Radiol 42:211-4. 2012..Others suggest that the forward propagation of the right ventricular systolic pressure pulse is the major contributor to the S wave... - Echocardiographic assessment of right ventricular volumes: a comparison of different techniques in children after surgical repair of tetralogy of FallotAndrea Dragulescu
Division of Cardiology, Labatt Family Heart Centre, Department of Pediatrics, Hospital for Sick Children, 555, University Avenue, Toronto, Canada M5G 1X8
Eur Heart J Cardiovasc Imaging 13:596-604. 2012..We compared the feasibility, reproducibility and accuracy of three different echocardiographic techniques for measuring RV volumes and ejection fraction (EF) in children after tetralogy of Fallot (TOF) repair... - Assessment of pulmonary veins after atrio-pericardial anastomosis by cardiovascular magnetic resonanceSteven C Greenway
Division of Cardiology, The Hospital for Sick Children, University of Toronto, Ontario, M5G 1X8, Canada
J Cardiovasc Magn Reson 13:72. 2011..We sought to compare the diagnostic value of echocardiography and CMR for assessing pulmonary vein anatomy after the APA... - Borderline hypoplasia of the left ventricle in neonates: insights for decision-making from functional assessment with magnetic resonance imagingLars Grosse-Wortmann
Labatt Family Heart Center at the Hospital for Sick Children, The University of Toronto, Toronto, Ontario, Canada
J Thorac Cardiovasc Surg 136:1429-36. 2008..We sought to compare the usefulness of echocardiography and magnetic resonance imaging in neonates with a borderline small left ventricle... - Magnetic guide-wire navigation in pulmonary and systemic arterial catheterization: initial experience in pigsLars Grosse-Wortmann
Department of Pediatric Cardiology, Aachen University Hospital, Pauwelsstrasse 30, 52057 Aachen, Germany
J Vasc Interv Radiol 18:545-51. 2007..This study addresses the feasibility of navigating a guide wire with a magnetic tip by an external magnetic field through pulmonary and systemic arteries in an experimental porcine model... - Anatomical and functional evaluation of pulmonary veins in children by magnetic resonance imagingLars Grosse Wortmann
Section of Cardiac Imaging, Department of Diagnostic Imaging, The Hospital for Sick Children, The University of Toronto, Toronto, Canada
J Am Coll Cardiol 49:993-1002. 2007.... - Exercise induces biventricular mechanical dyssynchrony in children with repaired tetralogy of FallotS Lucy Roche
The Labatt Family Heart Center, The Hospital for Sick Children, Toronto, Ontario, Canada
Heart 96:2010-5. 2010..This study investigated biventricular dyssynchrony in children with TOF and its relationship to exercise, QRS duration (QRSd) and ventricular mechanics... - Metric optimized gating for fetal cardiac MRIMichael S Jansz
Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
Magn Reson Med 64:1304-14. 2010..Metric optimized gating enables imaging with conventional phase-contrast magnetic resonance imaging sequences in the absence of a gating signal, permitting flow measurements in the great vessels in utero... - Gadolinium in pediatric cardiovascular magnetic resonance: what we know and how we practiceHoward Meng
The Labatt Family Heart Centre, The Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada
J Cardiovasc Magn Reson 14:56. 2012..We aimed at identifying current practice with regards to the use of GBCAs in children who undergo cardiovascular magnetic resonance... - Longitudinal right ventricular function is a better predictor of right ventricular contribution to exercise performance than global or outflow tract ejection fraction in tetralogy of Fallot: A combined echocardiography and Magnetic Resonance StudyMohammed H Alghamdi
Division of Cardiology, Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, Ontario, Canada M5G 1X8
Eur Heart J Cardiovasc Imaging 14:235-9. 2013..Our aim was to characterize the functional role of the RVOT and to identify the most suitable method of assessing RV systolic function in clinical practice... - Poor accuracy of noninvasive cardiac output monitoring using bioimpedance cardiography [PhysioFlow(R)] compared to magnetic resonance imaging in pediatric patientsKatherine Taylor
Department of Anesthesia, Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8, Canada
Anesth Analg 114:771-5. 2012.... - Mesenchymal hamartoma: prenatal diagnosis by MRILeysia Chu
Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Canada
Pediatr Radiol 41:781-4. 2011..An awareness of the characteristic imaging findings will allow accurate diagnosis of this condition, even prenatally, and thus facilitate appropriate perinatal management and surgical planning... - Transpleural pulmonary-to-systemic venous collaterals in a case with obstructed scimitar veinDerek T H Wong
Division of Cardiology, Department of Pediatrics, The Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Canada
Pediatr Cardiol 31:1086-8. 2010..MRI clearly demonstrated transpleural pulmonary-to-systemic venous collaterals draining the obstructed scimitar vein... - Unexpected contained rupture of a ductus arteriosus aneurysm found at surgical repair in an infant with Loeys-Dietz syndromeFrederic Jacques
Department of Surgery and Pediatrics, Division of Cardiovascular Surgery, Labatt Family Heart Centre, Toronto, Ontario, Canada
Ann Thorac Surg 95:710-1. 2013..We report the successful surgical management in a 1-month-old infant with Loeys-Dietz syndrome of a ductus arteriosus aneurysm with an unexpected contained rupture found at the time of surgery... - Images in cardiovascular medicine. Bilateral vertical veins from a common confluence in supracardiac total anomalous pulmonary venous connectionLars Grosse-Wortmann
Labatt Family Heart Center at the Hospital for Sick Children, University of Toronto, Toronto, Canada
Circulation 118:e103-4. 2008 - Cardiovascular MRI without sedation or general anesthesia using a feed-and-sleep technique in neonates and infantsJonathan Windram
Department of Diagnostic Imaging, Hospital for Sick Children, 555 University Ave, Toronto, Canada M5G 1X8
Pediatr Radiol 42:183-7. 2012..MRI in small children generally necessitates the use of general anesthesia... - Magnetic resonance imaging assessment of arrhythmogenic right ventricular cardiomyopathy/dysplasia in childrenShi Joon Yoo
Department of Diagnostic Imaging, The Hospital for Sick Children and Research Institute, University of Toronto, Ontario, Canada
Korean Circ J 40:357-67. 2010..Importantly, MRI should be performed and interpreted by experienced examiners to reduce the number of false positive and false negative readings... - Whole-body MR angiography: initial experience in imaging pediatric vasculopathyTerence S Hong
Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, M5G 1X8, Canada
Pediatr Radiol 41:769-78. 2011..WB-MRA has not been employed in the routine assessment of pediatric vascular disease. The purpose of this article is to describe and illustrate our WB-MRA imaging technique for evaluation of pediatric vasculopathy...