Research Topics
| Adrienne EinarsonSummaryAffiliation: The Hospital for Sick Children Country: Canada Publications
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Detail Information
Publications
Counseling pregnant women treated with paroxetine. Concern about cardiac malformationsAdrienne Einarson
Can Fam Physician 52:593-4. 2006..Failure to treat depression during pregnancy can have severe consequences for both mothers and babies and is the strongest predictor of postpartum depression...
Longitudinal study of depression, anxiety, irritability, and stress in pregnancy following evidence-based counseling on the use of antidepressantsLisa O'Brien
Hospital for Sick Children, Toronto and Institute of Medical Science, University of Toronto
J Psychiatr Pract 13:33-9. 2007..Little information exists on the effect of continuation of antidepressants on depressive symptoms during pregnancy...
Smoking in pregnancy and lactation: a review of risks and cessation strategiesAdrienne Einarson
The Hospital for Sick Children, Division of Clinical Pharmacology, University of Toronto, Toronto, ON, Canada
Eur J Clin Pharmacol 65:325-30. 2009..Despite documented evidence of harm to fetus and infant, a substantial number of women continue to smoke during pregnancy and lactation...- Challenges for healthcare providers in treating women with psychiatric disorders during pregnancyAdrienne Einarson
The Motherisk Program, The Hospital for Sick Children, Toronto, Ontario, Canada
J Popul Ther Clin Pharmacol 19:e371-5. 2012.... - Do findings differ across research design? The case of antidepressant use in pregnancy and malformationsThomas R Einarson
The Motherisk Program, The Hospital for Sick Children, Toronto, Ontario, Canada
J Popul Ther Clin Pharmacol 19:e334-48. 2012..Many studies examining the teratogenic potential of antidepressants have been published. A variety of observational designs have been used with apparent conflicting results, although odds ratios were rarely >2... - Seroprevalence of Toxoplasma gondii infection among veterinary staff in Ontario, Canada (2002): implications for teratogenic riskSamar Shuhaiber
The Motherisk Program, Division of Clinical Pharmacology Toxicology, The Hospital for Sick Children, University of Toronto, Ontario, Canada
BMC Infect Dis 3:8. 2003..gondii antibody among veterinary staff, to ascertain whether they have an increased risk through occupational exposure. Our secondary objective was to examine their practices regarding cats, toxoplasma infection, and pregnancy... - A survey of physicians knowledge regarding awareness of maternal alcohol use and the diagnosis of FASAlexandra C Nevin
The University of Toronto Medical School
BMC Fam Pract 3:2. 2002..The objectives of this study were twofold: 1) to evaluate the experience, knowledge and confidence of family physicians with respect to the diagnosis of FAS and 2) to evaluate physicians awareness of maternal drinking patterns... - Incidence of major malformations in infants following antidepressant exposure in pregnancy: results of a large prospective cohort studyAdrienne Einarson
The Motherisk Program, The Hospital for Sick Children, Toronto, Ontario, Canada
Can J Psychiatry 54:242-6. 2009..To ascertain if antidepressants, as a group, increase the risk for major malformations, as well as assessing each individual antidepressant... - How physicians perceive and utilize information from a teratogen information service: the Motherisk ProgramAdrienne Einarson
The Motherisk Program, The Hospital for Sick Children Toronto, Canada
BMC Med Educ 4:6. 2004..Our primary objective was to evaluate the perception and utilization of information received from us by physicians. Our secondary objective was to examine their information seeking behavior, in particular regarding teratogen information... - The safety of psychotropic drug use during pregnancy: a reviewAdrienne Einarson
The Motherisk Program, Division of Clinical Pharmacology Toxicology, The Hospital for Sick Children, The University of Toronto, Ontario, Canada
MedGenMed 7:3. 2005.... - Evaluation of the risk of congenital cardiovascular defects associated with use of paroxetine during pregnancyAdrienne Einarson
Motherisk Program, Hospital for Sick Children, Division of Clinical Pharmacology, University of Toronto, 555 University Ave, Toronto, Ontario M5G 1X8, Canada
Am J Psychiatry 165:749-52. 2008..In this study, the authors sought to determine whether paroxetine was associated with an increased risk of cardiovascular defects in infants of women exposed to the drug during the first trimester of pregnancy... - Quality and content of abstracts in papers reporting about drug exposures during pregnancyThomas R Einarson
Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada
Birth Defects Res A Clin Mol Teratol 76:621-8. 2006..Our objectives were to evaluate the quality of information in abstracts reporting human fetal outcomes following drug exposure during pregnancy... - Prescribing antidepressants to pregnant women: what is a family physician to do?Adrienne Einarson
Motherisk Program, Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8
Can Fam Physician 53:1412-4, 1423-5. 2007 - Adverse effects of antidepressant use in pregnancy: an evaluation of fetal growth and preterm birthA Einarson
The Motherisk Program, The Hospital for Sick Children, Toronto, Canada
Depress Anxiety 27:35-8. 2010..To compare the rates of low birth weight, preterm delivery and small for gestational age (SGA), in pregnancy outcomes among women who were exposed and nonexposed to antidepressants during pregnancy... - Nausea and vomiting of pregnancy (NVP) and depression: cause or effect?Pina Bozzo
The Motherisk Program, The Hospital forSick Children, Toronto, Canada
Clin Invest Med 34:E245. 2011..Several studies have linked depression with nausea and vomiting of pregnancy (NVP); however, researchers were unable to determine whether depression was caused by NVP or by a pre-existing condition... - Outcomes of infants exposed to multiple antidepressants during pregnancy: results of a cohort studyA Einarson
The Motherisk Program, The Hospital for Sick Children, Toronto, Canada
J Popul Ther Clin Pharmacol 18:e390-6. 2011..A single study has been published documenting an increased risk for adverse pregnancy outcomes following use of more than one antidepressant during pregnancy... - Exposure to mirtazapine during pregnancy: a prospective, comparative study of birth outcomesJosephine Djulus
Motherisk Program, Division of Clinical Pharmacology, The Hospital for Sick Children, Toronto, Ontario, Canada
J Clin Psychiatry 67:1280-4. 2006..However, the higher number of spontaneous abortions in the antidepressant groups confirms the higher rates of spontaneous abortions in pregnant women taking antidepressant medications found in previous studies... - Pregnancy outcome of women using atypical antipsychotic drugs: a prospective comparative studyKate McKenna
Motherisk Program, The Hospital for Sick Children, Toronto, Ontario, Canada
J Clin Psychiatry 66:444-9; quiz 546. 2005..05), and the rate of therapeutic abortions (p = .003). CONCLUSION: These results suggest that atypical antipsychotics do not appear to be associated with an increased risk for major malformations... - Prospective comparative study of the safety and effectiveness of ginger for the treatment of nausea and vomiting in pregnancyGalina Portnoi
The Motherisk Program, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
Am J Obstet Gynecol 189:1374-7. 2003..3+/-2.9 SD. CONCLUSION: These results suggest that ginger does not appear to increase the rates of major malformations above the baseline rate of 1% to 3% and that it has a mild effect in the treatment of NVP... - Determinants of women's decision making on whether to treat nausea and vomiting of pregnancy pharmacologicallyAnne Baggley
The Motherisk Program, The Hospital for Sick Children, Toronto, Ontario, Canada
J Midwifery Womens Health 49:350-4. 2004..Of the women who did use Diclectin, the most convincing reassuring information that it was safe to use came from friends and family. Many other factors play a large role in a women's decision making... - Pregnancy outcomes following use of escitalopram: a prospective comparative cohort studyChagit Klieger-Grossmann
Motherisk Program, The Hospital for Sick Children, Toronto, Ontario, Canada
J Clin Pharmacol 52:766-70. 2012..In addition, the higher rates of spontaneous abortions in both antidepressant groups confirmed previous findings... - MotherNature: establishing a Canadian research network for natural health products (NHPs) during pregnancy and lactationGideon Koren
Motherisk Program, Hospital for Sick Children, Toronto, Ontario, Canada
J Altern Complement Med 14:369-72. 2008.... - The safety of ondansetron for nausea and vomiting of pregnancy: a prospective comparative studyAdrienne Einarson
The Motherisk Program, The Hospital for Sick Children, The University of Toronto, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8
BJOG 111:940-3. 2004..CONCLUSIONS: This drug does not appear (although the sample size is limited) to be associated with an increased risk for major malformations above baseline... - Paroxetine and congenital malformations: meta-Analysis and consideration of potential confounding factorsBenjamin Bar Oz
Motherisk Program, The Hospital for Sick Children, Toronto, Ontario, Canada
Clin Ther 29:918-26. 2007..Antidepressants have been commonly used by women of childbearing age. Recent studies suggest that paroxetine, a selective serotonin reuptake inhibitor (SSRI), might specifically increase teratogenic risk... - Does paroxetine cause cardiac malformations?Lisa O'Brien
The Motherisk Program, The Hospital for Sick Children, Toronto, Toronto ON
J Obstet Gynaecol Can 30:696-701. 2008..Debate has recently arisen about the safety of paroxetine use in pregnancy, prompted by reports of increased risks for cardiac defects following first trimester exposure... - A pilot study of paternal drug exposure: the Motherisk experienceCandace Y W Lee
Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
Reprod Toxicol 29:353-60. 2010..Here, we reviewed for the first time our experience with PEx... - Citalopram use in pregnancy: prospective comparative evaluation of pregnancy and fetal outcomeAnna Sivojelezova
The Motherisk Program, Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Ontario, Canada
Am J Obstet Gynecol 193:2004-9. 2005..The safety of this medication in pregnancy has not been fully established. The purpose of this study was to investigate whether citalopram is associated with an increased incidence of adverse pregnancy outcomes... - Glucosamine use in pregnancy: an evaluation of pregnancy outcomeAnna Sivojelezova
The Motherisk Program, Division of Clinical Pharmacology, The Hospital for Sick Children, The University of Toronto, Canada
J Womens Health (Larchmt) 16:345-8. 2007..There is no information regarding its use in pregnancy. Our objective was to determine whether GLS treatment in pregnancy is associated with an increased risk of major malformations or other adverse outcomes... - Is maternal use of selective serotonin reuptake inhibitors in the third trimester of pregnancy harmful to neonates?Gideon Koren
Motherisk Program, The Hospital for Sick Children and University of Toronto, Toronto, Ont
CMAJ 172:1457-9. 2005 - FDA pregnancy risk categories and the CPS: do they help or are they a hindrance?Ruth Law
Leslie Dan Faculty of Pharmacy, University of Toronto
Can Fam Physician 56:239-41. 2010..The FDA announced in May 2008 that it is dropping its pregnancy risk categories and adopting a method similar to the one we use at Motherisk... - Providing information regarding exposures in pregnancy: a survey of North American Teratology Information ServicesRebecca L Hancock
Department of Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Canada
Reprod Toxicol 25:381-7. 2008..Teratology Information Services (TIS) provide information on exposures during pregnancy and breast-feeding. Maintaining ongoing funding is a challenge. The purpose was to gather descriptive information on current TIS operations... - Abrupt discontinuation of psychotropic drugs following confirmation of pregnancy: a risky practiceAdrienne Einarson
Motherisk Program, The Hospital for Sick Children, Toronto, ON
J Obstet Gynaecol Can 27:1019-22. 2005..Therefore, it is not good practice to discontinue these medications abruptly upon diagnosis of pregnancy... - The effectiveness of Teratology Information Services (TIS)Rebecca L Hancock
Department of Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Canada
Reprod Toxicol 23:125-32. 2007..The objective of this review is to highlight published reports of the effectiveness of TIS in improving maternal and neonatal health... - The safety of antidepressant use in pregnancySanjog Kalra
The Hospital for Sick Children, The Motherisk Program, Division of Clinical Pharmacology and Toxicology, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
Expert Opin Drug Saf 4:273-84. 2005..This evidence-based information will be helpful to women and their healthcare providers, when the decision of whether or not to treat with anti-depressants during pregnancy must be made... - Rates of spontaneous and therapeutic abortions following use of antidepressants in pregnancy: results from a large prospective databaseAdrienne Einarson
The Motherisk Program, The Hospital for Sick Children, Toronto, ON
J Obstet Gynaecol Can 31:452-6. 2009..We sought to examine whether use of antidepressants increases the rates of spontaneous abortion (SA) and therapeutic abortion (TA) in women exposed in early pregnancy... - Use and safety of antipsychotic drugs during pregnancyAdrienne Einarson
Motherisk Program, Division of Clinical Pharmacology, The Hospital for Sick Children, University of Toronto, Canada
J Psychiatr Pract 15:183-92. 2009.... - Pregnancy outcome of women exposed to bupropion during pregnancy: a prospective comparative studyBrian Chun-Fai-Chan
The Motherisk Program, The Hospital for Sick Children, Toronto, Ontario, Canada
Am J Obstet Gynecol 192:932-6. 2005..The higher rates of spontaneous abortions are similar to other studies examining the safety of antidepressants during pregnancy... - Knowledge transfer and translation: examining how teratogen information is disseminatedIlan Shahin
University of Toronto, Toronto, Ontario, Canada
Birth Defects Res A Clin Mol Teratol 91:956-61. 2011..Therefore, it is important to disseminate evidenced-based information to pregnant women and their health care providers, enabling them to make empowered decisions regarding exposures during pregnancy... - Risks/safety of psychotropic medication use during pregnancy--Motherisk Update 2008Adrienne Einarson
The Motherisk Program, The Hospital for Sick Children, Toronto, Ontario
Can J Clin Pharmacol 16:e58-65. 2009..All pregnancies where a mother has a serious psychiatric disorder should be considered high risk and the mother and fetus must be carefully monitored... - International practices in the provision of teratology information: a survey of international teratogen information programmes and comparisons with the North American modelRebecca L Hancock
University of Toronto, Institute of Medical Science, Department of Child Health Evaluative Sciences, Hospital for Sick Children, Toronto, ON, Canada
J Eval Clin Pract 16:957-63. 2010..The survey objective was to compare international TIS to North American TIS, with an aim to identify strengths and challenges that can lead to service improvement... - Newer antidepressants in pregnancy and rates of major malformations: a meta-analysis of prospective comparative studiesThomas R Einarson
Faculty of Pharmacy, Department of Clinical Pharmacology, Faculty of Medicine, University of Toronto, Ont, Canada
Pharmacoepidemiol Drug Saf 14:823-7. 2005..The summary relative risk was 1.01 (95%CI: 0.57-1.80). CONCLUSIONS: As a group, the newer antidepressants are not associated with an increased risk of major malformations above the baseline of 1-3% in the population... - Proceedings from Motherisk Update 2008. Introduction: reproductive mental healthAdrienne Einarson
The Motherisk Program, The Hospital for Sick Children, Toronto, Canada
Can J Clin Pharmacol 16:e1-5. 2009.... - Diclectin therapy for nausea and vomiting of pregnancy: effects of optimal dosingRada Boskovic
The Motherisk Program, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
J Obstet Gynaecol Can 25:830-3. 2003..1) To quantify rates of suboptimal use of pyridoxine hydrochloride-doxylamine (Diclectin); and (2) to study responses to optimal doses of Diclectin in women previously taking a suboptimal dose... - Perception of teratogenic risk and the rated likelihood of pregnancy termination: association with maternal depressionAsnat Walfisch
The Motherisk Program, The Hospital for Sick Children, Toronto, Ontario
Can J Psychiatry 56:761-7. 2011..Our objectives were to explore the association between maternal depression, teratogenic risk perception, and the rated likelihood to terminate pregnancy. Additionally, we evaluated possible benefits of counselling... - Introduction: reproductive mental health--Motherisk update 2008Adrienne Einarson
The Motherisk Program, The Hospital for Sick Children, Toronto, Canada
Can J Clin Pharmacol 16:e1-5. 2009.... - Montelukast use during pregnancy: a multicentre, prospective, comparative study of infant outcomesMoumita Sarkar
The Motherisk Program, Toronto, Canada
Eur J Clin Pharmacol 65:1259-64. 2009..Currently, there are limited prospective, comparative studies in the literature examining the safety of montelukast use in pregnancy... - Trimethoprim-sulfonamide combination therapy in early pregnancyAnna Sivojelezova
Hospital for Sick Children, Toronto, Ont
Can Fam Physician 49:1085-6. 2003..If clinically possible, physicians are advised to use alternative antimicrobial medications for treatment of urinary tract infections during early pregnancy... - Antidepressant use during pregnancy and the rates of spontaneous abortions: a meta-analysisMichiel E H Hemels
Department of Pharmacology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Ann Pharmacother 39:803-9. 2005..45 (1.19 to 1.77; n = 3567). No differences were found among antidepressant classes. CONCLUSIONS: Maternal exposure to antidepressants may be associated with increased risk for SA; however, depression itself cannot be ruled out... - New antidepressants in pregnancyAdrienne Einarson
Hospital for Sick Children, Toronto, Ont
Can Fam Physician 50:227-9. 2004.... - Effectiveness of bupropion for smoking cessation during pregnancyBrian Chan
Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, Canada
J Addict Dis 24:19-23. 2005..047). Bupropion appears to be effective for smoking cessation therapy during pregnancy... - The Motherisk Alcohol and Substance Use Helpline: 10 years of experience and countingEunji Kim
The Alcohol and Substance use Helpline, The Motherisk Program, The Hospital for Sick Children, Toronto, Canada
J Popul Ther Clin Pharmacol 17:e269-80. 2010..Thus, further efforts are required to reach out to the subgroup of women at high risk of continuing their harmful behaviors during pregnancy and lactation... - Negative impact of non-evidence-based information received by women taking antidepressants during pregnancy from health care providers and othersEva Mulder
The Motherisk Program, The Hospital for Sick Children, Toronto, ON
J Obstet Gynaecol Can 34:66-71. 2012.... - Perinatal risks of untreated depression during pregnancyLori Bonari
The Hospital for Sick Children and the Department of of Pharmacology, University of Toronto, Toronto, Ontario
Can J Psychiatry 49:726-35. 2004..Because they are not aware of the potentially catastrophic outcome of untreated maternal depression, this imbalance may lead women suffering from depression to fear teratogenic effects and refuse treatment... - Ruminative worrying during pregnancy: a case seriesAdrienne Einarson
The Motherisk Program, The Hospital for Sick Children, Toronto, ON, Canada, and The Women's Life Center of The Semel Institute for Neuroscience and Human Behavior, Geffen School of Medicine at UCLA, Los Angeles, CA, USA
J Obstet Gynaecol Can 28:724-7. 2006..CONCLUSION: A collaborative effort between caregivers in psychiatry and obstetrics, as well as other health professionals, is required to provide management for these women during pregnancy... - Risks of untreated depression during pregnancyLori Bonari
Motherisk Team, Hospital for Sick Children, Toronto, Ont
Can Fam Physician 50:37-9. 2004.... - Antidepressant use in pregnancy and persistent pulmonary hypertension of the newborn (PPHN): a systematic reviewGeert W 't Jong
The Motherisk Program, Division of Clinical Pharmacology, Hospital for Sick Children, Toronto, Canada
Reprod Toxicol 34:293-7. 2012..An association between PPHN and antidepressant use in pregnancy has been reported... - Pregnant women's perception of risk with use of the H1N1 vaccineSachi Sakaguchi
The Motherisk Program, Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario
J Obstet Gynaecol Can 33:460-7. 2011..We wished to explore pregnant women's perception of risk and the factors associated with deciding whether or not to receive the vaccine... - Safety of triptans for migraine headaches during pregnancy and breastfeedingSilvia Duong
Leslie Dan Faculty of Pharmacy, University of Toronto, Canada
Can Fam Physician 56:537-9. 2010..Information regarding safety of triptans while breastfeeding is limited but also reassuring, as the minimal amounts excreted into the milk are insufficient to cause any adverse effects on the breastfeeding infant... - Significant changes in antipsychotic drug use during pregnancyKate McKenna
Department of Pharmacology, University of Toronto, Toronto, Ontario, Canada
Vet Hum Toxicol 46:44-6. 2004..Since the introduction of atypical antipsychotics, more women requiring antipsychotic drug therapy have been planning or becoming pregnant. This increase may have substantial public health implications... - Treatment of heartburn and acid reflux associated with nausea and vomiting during pregnancyRuth Law
Leslie DanFaculty of Pharmacy, University of Toronto, Toronto, Canada
Can Fam Physician 56:143-4. 2010..Antacids, histamine-2 receptor antagonists, and proton pump inhibitors can be used safely during pregnancy, as large studies have been published with no evidence of adverse fetal effects... - A multicentre prospective controlled study to determine the safety of trazodone and nefazodone use during pregnancyAdrienne Einarson
Motherisk Program, Division of Clinical Pharmacology, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8
Can J Psychiatry 48:106-10. 2003..Secondary outcomes of interest included rates of spontaneous and therapeutic abortions, rates of premature labour, and birth weight... - The incidence of nausea and vomiting of pregnancy (NVP): a comparison between depressed women treated with antidepressants and non-depressed womenPina Bozzo
The Motherisk Program, The Hospital for Sick Children, Toronto, Ontario, Canada
Clin Invest Med 29:347-50. 2006..In many cases NVP causes changes i n family, social, o roccupational functioning. Several studies have linked NVP with depression; however, whether depression preceded or resulted from NVP, has not been established... - Taking ginger for nausea and vomiting during pregnancyKiran Chandra
Hospital for Sick Children, Toronto, Ont
Can Fam Physician 48:1441-2. 2002..On the other hand, its efficacy has been documented in two randomized, blinded controlled trials... - Outcome following high-dose methotrexate in pregnancies misdiagnosed as ectopicLaila Nurmohamed
Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, ON, Canada
Am J Obstet Gynecol 205:533.e1-3. 2011..The objective of this study was to report the outcomes of intrauterine pregnancies misdiagnosed as ectopic and exposed to methotrexate, a major teratogen... - Update on motherisk updates. Seven years of questions and answersAdrienne Einarson
Hospital for Sick Children, Toronto, Ont
Can Fam Physician 48:1301-4. 2002..Most questions are about drug exposures. The three classes of drugs asked about most often are antidepressants, antiepileptics, and antihistamines... - Motherisk-PUQE (pregnancy-unique quantification of emesis and nausea) scoring system for nausea and vomiting of pregnancyGideon Koren
Motherisk Program, The Hospital for Sick Children, Toronto, Ontario, Canada
Am J Obstet Gynecol 186:S228-31. 2002..95;P <.0001). CONCLUSION: The new PUQE score yields similar results to the gold standard, but more cumbersome, Rhode's score. Clinicians and researchers can easily use PUQE... - The use of CAM by women suffering from nausea and vomiting during pregnancyTaras Hollyer
Canadian College of Naturopathic Medicine, Toronto, Canada
BMC Complement Altern Med 2:5. 2002..Our primary objective was to examine the prevalence of CAM usage by women suffering from NVP. Our secondary objective was to ascertain if women had any supervision in the use of these treatments... - Prevalence of depression during pregnancy: systematic reviewHeather A Bennett
Faculty of Pharmacy and Department of Medicine, University of Toronto, Ontario, Canada
Obstet Gynecol 103:698-709. 2004.... - The safety of drugs for the treatment of nausea and vomiting of pregnancySimerpal K Gill
The Hospital for Sick Children, The Motherisk Program, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada
Expert Opin Drug Saf 6:685-94. 2007..Also included is a treatment algorithm that can assist the healthcare provider in treating this condition in pregnant safely and effectively... - Safety of hair products during pregnancy: personal use and occupational exposureAngela Chua-Gocheco
Motherisk Team, Hospital for Sick Children, Toronto, Ont
Can Fam Physician 54:1386-8. 2008..Evidence suggests there is minimal systemic absorption of hair products, so personal use by pregnant women 3 to 4 times throughout pregnancy is not considered to be of concern... - The relationship between stress and hair cortisol in healthy pregnant womenSanjog Kalra
The Motherisk Program, Hospital for Sick Children and University of Toronto, ON, Canada
Clin Invest Med 30:E103-7. 2007..Stress has been shown to cause a large range of adverse fetal effects. This pilot study is the first attempt to examine cortisol level in the hair of pregnant women and assess its potential as a biomarker of gestational stress... - Do we have a knowledge transfer and translation plan at Teratogen Information Services?Adrienne Einarson
The Motherisk Program, Population Health Sciences, Division of Clinical Pharmacology, The Hospital for Sick Children, The University of Toronto, 555 University Avenue, Toronto, Ont, Canada M5G 1X8
Reprod Toxicol 22:542-5. 2006..In this brief review/comment, an attempt will be made to help the readers understand the meaning of this new terminology and how it impacts Teratogen Information Services... - Herbal medicine use in pregnancy: a new frontier in clinical teratologyMichael Gallo
The Motherisk Program, The Hospital for Sick Children, Toronto, Ontario, Canada
Birth Defects Res B Dev Reprod Toxicol 68:499-500. 2003 - Nausea and vomiting of pregnancy. Evidence-based treatment algorithmZina Levichek
Hospital for Sick Children, Toronto, Ont
Can Fam Physician 48:267-8, 277. 2002..What should my priority be? ANSWER: An algorithm used by Motherisk to manage thousands of patients takes a hierarchical approach to this condition. This approach is evidence based with regard to fetal safety as well as efficacy... - Vaginal yeast infections during pregnancyDerrick Soong
Leslie Dan Faculty of Pharmacy, University of Toronto
Can Fam Physician 55:255-6. 2009..Topical azole antifungals are the recommended treatment during pregnancy for at least 7 days owing to increased efficacy. Topical corticosteroids can be used for symptomatic relief... - Electric shock during pregnancyRan D Goldman
Motherisk Team at the Hospital for Sick Children, Toronto, Ont, Canada
Can Fam Physician 49:297-8. 2003..In this case, it appears the current did not travel through her abdomen. Recommendations for fetal monitoring after electrocution have been published... - A prospective-controlled study of pregnant veterinary staff exposed to inhaled anesthetics and x-raysSamaer Shuhaiber
Faculty of Pharmacy, University of Toronto, Motherisk Program, Division of Clinical Pharmacology/Toxicology, Hospital for Sick Children, Toronto, Ontario, Canada
Int J Occup Med Environ Health 15:363-73. 2002..4%) cases in the control group. These results suggest that Ontario female veterinary staff exposed to inhaled anesthetics and/or radiation do not seem to be at an increased risk for major malformations above baseline risk... - SSRIs and birth defectsVivien Burt
Epidemiology 18:410-1; author reply 412-3. 2007 - Re: use of contemporary antidepressants during breastfeeding: a proposal for a specific safety indexAdrienne Einarson
Drug Saf 30:643; author reply 643-4. 2007 - Comment: paroxetine use during pregnancy: is it safe?Wende Wood
Ann Pharmacother 40:2281-2. 2006 - Cancer in pregnancy: Motherisk on-line question and answer forumSandy Grupp
Can Fam Physician 53:1891-2. 2007..Questions about the safety of chemotherapeutic drugs before and during pregnancy and about possible exacerbation of previous cancer by pregnancy are most common... - Defective alleles may not have contributed to adverse effectsAdrienne Einarson
Ther Drug Monit 28:142-3; author reply 143. 2006 - Pregnancy and antidepressant counselingAdrienne Einarson
Am J Psychiatry 161:2137. 2004 - Use of warfarin during pregnancyShirin Abadi
Hospital for Sick Children in Toronto, Ont
Can Fam Physician 48:695-7. 2002..Unfractionated heparin or low molecular weight heparin could be substituted when appropriate because these agents do not cross the placenta and are considered the anticoagulant drugs of choice during pregnancy... - Problems with maternal antidepressant treatment and neonatal outcomes studyThomas R Einarson
Arch Gen Psychiatry 64:866; author reply 867-8. 2007 - Physicians' participation in researchShauna Tsuchiya
CMAJ 176:1861. 2007 - Effects and treatment of inflammatory bowel disease during pregnancyHarvinder Brar
Can Fam Physician 54:981-3. 2008..There are limited data on the use of infliximab during pregnancy, although no pattern of defects or complications has been reported to date... - Treatment of nausea and vomiting in pregnancy: an updated algorithmAdrienne Einarson
Can Fam Physician 53:2109-11. 2007 - Smoking habits, nicotine use, and congenital malformationsAdrienne Einarson
Obstet Gynecol 107:1167; author reply 1168. 2006