Research Topics
| Mark W CrawfordSummaryAffiliation: The Hospital for Sick Children Country: Canada Publications
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Detail Information
Publications
Propofol syndrome in childrenMark W Crawford
CMAJ 168:669; author reply 669-70. 2003- Preparation of the Dräger Primus anesthetic machine for malignant hyperthermia-susceptible patientsHeike Prinzhausen
Department of Anesthesia, The Hospital for Sick Children, Toronto, Ontario, Canada
Can J Anaesth 53:885-90. 2006..min(-1). We recommend maintaining a FGF of 10 L.min(-1) for the duration of anesthesia in order to prevent the rebound increase in anesthetic concentration in the FGF... - Extent and localization of changes in upper airway caliber with varying concentrations of sevoflurane in childrenMark W Crawford
Department of Anesthesia, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8
Anesthesiology 105:1147-52; discussion 5A. 2006.... - Dose-dependent suppression of the electrically elicited stapedius reflex by general anesthetics in children undergoing cochlear implant surgeryMark W Crawford
Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Anesth Analg 108:1480-7. 2009..In this study, we evaluated the dose-related effects of sevoflurane, desflurane, isoflurane, and propofol on the intraoperative ESRT and ECAP... - Effect of propofol anesthesia and continuous positive airway pressure on upper airway size and configuration in infantsMark W Crawford
Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Ontario, Canada
Anesthesiology 105:45-50. 2006..The authors studied the interaction of propofol anesthesia and CPAP on airway caliber in infants using magnetic resonance imaging... - Postoperative morphine consumption in children with sickle-cell diseaseMark W Crawford
Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
Paediatr Anaesth 16:152-7. 2006..To understand analgesic requirements better, the authors compared postoperative morphine consumption and pain scores in sickle and non-sickle children who had undergone laparoscopic cholecystectomy... - Preoperative screening for sickle cell disease in children: clinical implicationsMark W Crawford
Department of Anesthesia, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada
Can J Anaesth 52:1058-63. 2005..We undertook a retrospective study to determine the prevalence of positive test results among those screened preoperatively at our institution and to determine whether amendments to present screening guidelines can be recommended... - The upper airway in Weaver syndromeMark W Crawford
Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Ontario, Canada
Paediatr Anaesth 15:893-6. 2005.... - Dose-response of remifentanil for tracheal intubation in infantsMark W Crawford
Department of Anesthesia, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario, Canada M5G 1X8
Anesth Analg 100:1599-604. 2005..Propofol/remifentanil provides clinically acceptable intubating conditions, stable hemodynamics, and a duration of apnea comparable to that with propofol/succinylcholine in infants... - Accelerating the washout of inhalational anesthetics from the Dräger Primus anesthetic workstation: effect of exchangeable internal componentsMark W Crawford
Department of Anesthesia, The Hospital for ick Children, University of Toronto, Canada
Anesthesiology 106:289-94. 2007.... - Acute chest syndrome shows a predilection for basal lung regions on the side of upper abdominal surgeryMark W Crawford
Department of Anesthesia, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
Can J Anaesth 51:707-11. 2004..The acute chest syndrome (ACS) is the most common sickle-related postoperative complication. The objective of the study was to characterize the clinical and radiological presentation of ACS complicating cholecystectomy and splenectomy... - Magnesium deficiency alters the threshold for epinephrine-induced arrhythmias during halothane or sevoflurane anesthesia in the ratMark W Crawford
Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
J Cardiothorac Vasc Anesth 18:313-6. 2004..To determine the effect of chronic magnesium (Mg2+) deficiency on the relative arrhythmogenicity of halothane and sevoflurane in the rat... - The novel hemoglobin-based oxygen carrier HRC 101 improves survival in murine sickle cell diseaseMark W Crawford
Department of Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Canada
Anesthesiology 107:281-7. 2007.... - Development of acute opioid tolerance during infusion of remifentanil for pediatric scoliosis surgeryMark W Crawford
Department of Anesthesia, Division of Orthopedic Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Anesth Analg 102:1662-7. 2006..These data suggest that intraoperative infusion of remifentanil is associated with the development of clinically relevant acute opioid tolerance in adolescents undergoing scoliosis surgery... - Intraoperative low-dose ketamine does not prevent a remifentanil-induced increase in morphine requirement after pediatric scoliosis surgeryThomas Engelhardt
Department of Anesthesia, The Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, Ontario, Canada M5G 1X8
Anesth Analg 107:1170-5. 2008.... - Pre-treatment with morphine does not prevent the development of remifentanil-induced hyperalgesiaConor McDonnell
Department of Anesthesia, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
Can J Anaesth 55:813-8. 2008..This study involving adolescents undergoing scoliosis surgery evaluated whether pre-treatment with morphine prior to commencing remifentanil infusion would decrease the initial 24-hr morphine consumption and pain scores... - Preparation of the Dräger Fabius GS workstation for malignant hyperthermia-susceptible patientsRobert J Whitty
Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON, M5G 1X8, Canada
Can J Anaesth 56:497-501. 2009.... - Drug-induced acute pancreatitis in children receiving chemotherapy for acute leukemia: does propofol increase the risk?Mark W Crawford
Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Anesth Analg 109:379-81. 2009..The use of propofol is controversial in patients with a history of acute pancreatitis or those taking drugs, including certain chemotherapeutic drugs, that are associated with pancreatitis... - Effect of low-dose ketamine on voltage requirement for transcranial electrical motor evoked potentials in childrenChristian Zaarour
Department of Anesthesia, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Spine (Phila Pa 1976) 32:E627-30. 2007.... - Effect of increasing depth of propofol anesthesia on upper airway configuration in childrenRussell G Evans
Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Ontario, Canada
Anesthesiology 99:596-602. 2003..CONCLUSION: Increasing depth of propofol anesthesia in children is associated with upper airway narrowing that occurs throughout the entire upper airway and is most pronounced in the hypopharynx at the level of the epiglottis... - PCA-derived factors that may be predictive of postoperative pain in pediatric patients: a possible role for the PCA ratioConor McDonnell
Department of Anesthesia and Pain Medicine, Hospital for Sick Children, University of Toronto, Toronto, Ontario
J Opioid Manag 8:39-44. 2012..The authors hypothesized that data derived from patient-controlled analgesia (PCA) pumps (specifically the ratio of patient demands to pump deliveries) may predict which patients would develop severe pain after scoliosis repair... - Plasma cyclic guanosine 3',5'-monophosphate levels: a marker of glutamate-nitric oxide-guanyl cyclase activity?Thomas Engelhardt
Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, Ontario, Canada
J Opioid Manag 7:462-6. 2011.... - Coadministration of propofol and remifentanil for lumbar puncture in children: dose-response and an evaluation of two dose combinationsJason A Hayes
Department of Anesthesia, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
Anesthesiology 109:613-8. 2008..The authors undertook a two-part study to evaluate coadministration of propofol and remifentanil as an anesthetic technique for lumbar puncture in children... - A pilot study of the rectus sheath block for pain control after umbilical hernia repairLisa A Isaac
Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
Paediatr Anaesth 16:406-9. 2006..DISCUSSION: Our results suggest that the rectus sheath block has no advantage over infiltration of local anesthetic into the surgical wound for postoperative pain management in children undergoing umbilical hernia repair... - Near-miss injection of an anesthetic agent into a cerebrospinal fluid external ventricular drain: special reportJames M Drake
Division of Neurosurgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Neurosurgery 56:E1161; discussion E1161. 2005..One method of error prevention is the reporting of a near-miss event. We report that intravenous anesthetic agents were nearly injected into the external ventricular drainage (EVD) of a patient during an emergency shunt procedure... - Complete upper airway obstruction after induction of anesthesia in a child with undiagnosed lingual tonsil hypertrophyMauro Arrica
Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
Paediatr Anaesth 16:584-7. 2006..More frequently described in adults than in children, LTH can complicate mask ventilation, intubation or both, with the potential for catastrophic consequences... - Carnitine deficiency increases susceptibility to bupivacaine-induced cardiotoxicity in ratsGail K Wong
Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Anesthesiology 114:1417-24. 2011..The authors hypothesized that carnitine deficiency increases susceptibility to bupivacaine-induced asystole in rats and that acute repletion with L-carnitine reverses this effect... - Cardiovascular MRI without sedation or general anesthesia using a feed-and-sleep technique in neonates and infantsJonathan Windram
Department of Diagnostic Imaging, Hospital for Sick Children, 555 University Ave, Toronto, Canada M5G 1X8
Pediatr Radiol 42:183-7. 2012..MRI in small children generally necessitates the use of general anesthesia... - Bibliographic characteristics of the research output of pediatric anesthesiologists in CanadaJames D O'Leary
The Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, ON, Canada
Can J Anaesth 57:573-7. 2010..Although described initially for physical sciences, h-indices are being used to assess research productivity and impact in other disciplines...