Mark W Crawford

Summary

Affiliation: The Hospital for Sick Children
Country: Canada

Publications

  1. pmc Propofol syndrome in children
    Mark W Crawford
    CMAJ 168:669; author reply 669-70. 2003
  2. ncbi request reprint Preparation of the Dräger Primus anesthetic machine for malignant hyperthermia-susceptible patients
    Heike Prinzhausen
    Department of Anesthesia, The Hospital for Sick Children, Toronto, Ontario, Canada
    Can J Anaesth 53:885-90. 2006
  3. ncbi request reprint The novel hemoglobin-based oxygen carrier HRC 101 improves survival in murine sickle cell disease
    Mark W Crawford
    Department of Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Canada
    Anesthesiology 107:281-7. 2007
  4. doi request reprint Dose-dependent suppression of the electrically elicited stapedius reflex by general anesthetics in children undergoing cochlear implant surgery
    Mark W Crawford
    Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Anesth Analg 108:1480-7. 2009
  5. ncbi request reprint Accelerating the washout of inhalational anesthetics from the Dräger Primus anesthetic workstation: effect of exchangeable internal components
    Mark W Crawford
    Department of Anesthesia, The Hospital for ick Children, University of Toronto, Canada
    Anesthesiology 106:289-94. 2007
  6. ncbi request reprint Extent and localization of changes in upper airway caliber with varying concentrations of sevoflurane in children
    Mark W Crawford
    Department of Anesthesia, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8
    Anesthesiology 105:1147-52; discussion 5A. 2006
  7. ncbi request reprint Effect of propofol anesthesia and continuous positive airway pressure on upper airway size and configuration in infants
    Mark W Crawford
    Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Ontario, Canada
    Anesthesiology 105:45-50. 2006
  8. ncbi request reprint Development of acute opioid tolerance during infusion of remifentanil for pediatric scoliosis surgery
    Mark W Crawford
    Department of Anesthesia, Division of Orthopedic Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Anesth Analg 102:1662-7. 2006
  9. ncbi request reprint Postoperative morphine consumption in children with sickle-cell disease
    Mark W Crawford
    Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
    Paediatr Anaesth 16:152-7. 2006
  10. ncbi request reprint Preoperative screening for sickle cell disease in children: clinical implications
    Mark W Crawford
    Department of Anesthesia, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada
    Can J Anaesth 52:1058-63. 2005

Collaborators

Detail Information

Publications33

  1. pmc Propofol syndrome in children
    Mark W Crawford
    CMAJ 168:669; author reply 669-70. 2003
  2. ncbi request reprint Preparation of the Dräger Primus anesthetic machine for malignant hyperthermia-susceptible patients
    Heike Prinzhausen
    Department of Anesthesia, The Hospital for Sick Children, Toronto, Ontario, Canada
    Can J Anaesth 53:885-90. 2006
    ..0 min). Increasing the FGF to 18 L.min(-1) decreased the washout time for isoflurane in the Primus, only moderately, to 52 min. We observed a threefold increase in anesthetic concentration in the Primus during the late washout phase...
  3. ncbi request reprint The novel hemoglobin-based oxygen carrier HRC 101 improves survival in murine sickle cell disease
    Mark W Crawford
    Department of Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Canada
    Anesthesiology 107:281-7. 2007
    ....
  4. doi request reprint Dose-dependent suppression of the electrically elicited stapedius reflex by general anesthetics in children undergoing cochlear implant surgery
    Mark W Crawford
    Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Anesth Analg 108:1480-7. 2009
    ..In this study, we evaluated the dose-related effects of sevoflurane, desflurane, isoflurane, and propofol on the intraoperative ESRT and ECAP...
  5. ncbi request reprint Accelerating the washout of inhalational anesthetics from the Dräger Primus anesthetic workstation: effect of exchangeable internal components
    Mark W Crawford
    Department of Anesthesia, The Hospital for ick Children, University of Toronto, Canada
    Anesthesiology 106:289-94. 2007
    ....
  6. ncbi request reprint Extent and localization of changes in upper airway caliber with varying concentrations of sevoflurane in children
    Mark W Crawford
    Department of Anesthesia, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8
    Anesthesiology 105:1147-52; discussion 5A. 2006
    ....
  7. ncbi request reprint Effect of propofol anesthesia and continuous positive airway pressure on upper airway size and configuration in infants
    Mark W Crawford
    Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Ontario, Canada
    Anesthesiology 105:45-50. 2006
    ..The authors studied the interaction of propofol anesthesia and CPAP on airway caliber in infants using magnetic resonance imaging...
  8. ncbi request reprint Development of acute opioid tolerance during infusion of remifentanil for pediatric scoliosis surgery
    Mark W Crawford
    Department of Anesthesia, Division of Orthopedic Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Anesth Analg 102:1662-7. 2006
    ..These data suggest that intraoperative infusion of remifentanil is associated with the development of clinically relevant acute opioid tolerance in adolescents undergoing scoliosis surgery...
  9. ncbi request reprint Postoperative morphine consumption in children with sickle-cell disease
    Mark W Crawford
    Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
    Paediatr Anaesth 16:152-7. 2006
    ..To understand analgesic requirements better, the authors compared postoperative morphine consumption and pain scores in sickle and non-sickle children who had undergone laparoscopic cholecystectomy...
  10. ncbi request reprint Preoperative screening for sickle cell disease in children: clinical implications
    Mark W Crawford
    Department of Anesthesia, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada
    Can J Anaesth 52:1058-63. 2005
    ..We undertook a retrospective study to determine the prevalence of positive test results among those screened preoperatively at our institution and to determine whether amendments to present screening guidelines can be recommended...
  11. ncbi request reprint The upper airway in Weaver syndrome
    Mark W Crawford
    Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Ontario, Canada
    Paediatr Anaesth 15:893-6. 2005
    ....
  12. ncbi request reprint Magnesium deficiency alters the threshold for epinephrine-induced arrhythmias during halothane or sevoflurane anesthesia in the rat
    Mark W Crawford
    Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    J Cardiothorac Vasc Anesth 18:313-6. 2004
    ..To determine the effect of chronic magnesium (Mg2+) deficiency on the relative arrhythmogenicity of halothane and sevoflurane in the rat...
  13. ncbi request reprint Dose-response of remifentanil for tracheal intubation in infants
    Mark W Crawford
    Department of Anesthesia, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario, Canada M5G 1X8
    Anesth Analg 100:1599-604. 2005
    ..Propofol/remifentanil provides clinically acceptable intubating conditions, stable hemodynamics, and a duration of apnea comparable to that with propofol/succinylcholine in infants...
  14. ncbi request reprint Acute chest syndrome shows a predilection for basal lung regions on the side of upper abdominal surgery
    Mark W Crawford
    Department of Anesthesia, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
    Can J Anaesth 51:707-11. 2004
    ..The acute chest syndrome (ACS) is the most common sickle-related postoperative complication. The objective of the study was to characterize the clinical and radiological presentation of ACS complicating cholecystectomy and splenectomy...
  15. doi request reprint Intraoperative low-dose ketamine does not prevent a remifentanil-induced increase in morphine requirement after pediatric scoliosis surgery
    Thomas Engelhardt
    Department of Anesthesia, The Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, Ontario, Canada M5G 1X8
    Anesth Analg 107:1170-5. 2008
    ....
  16. doi request reprint Pre-treatment with morphine does not prevent the development of remifentanil-induced hyperalgesia
    Conor McDonnell
    Department of Anesthesia, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
    Can J Anaesth 55:813-8. 2008
    ..This study involving adolescents undergoing scoliosis surgery evaluated whether pre-treatment with morphine prior to commencing remifentanil infusion would decrease the initial 24-hr morphine consumption and pain scores...
  17. doi request reprint Preparation of the Dräger Fabius GS workstation for malignant hyperthermia-susceptible patients
    Robert J Whitty
    Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON, M5G 1X8, Canada
    Can J Anaesth 56:497-501. 2009
    ....
  18. doi request reprint Drug-induced acute pancreatitis in children receiving chemotherapy for acute leukemia: does propofol increase the risk?
    Mark W Crawford
    Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Anesth Analg 109:379-81. 2009
    ..The use of propofol is controversial in patients with a history of acute pancreatitis or those taking drugs, including certain chemotherapeutic drugs, that are associated with pancreatitis...
  19. ncbi request reprint Effect of low-dose ketamine on voltage requirement for transcranial electrical motor evoked potentials in children
    Christian Zaarour
    Department of Anesthesia, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Spine (Phila Pa 1976) 32:E627-30. 2007
    ....
  20. ncbi request reprint Effect of increasing depth of propofol anesthesia on upper airway configuration in children
    Russell G Evans
    Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Ontario, Canada
    Anesthesiology 99:596-602. 2003
    ..The purpose of the current study was to determine the effect of increasing depth of propofol anesthesia on airway size and configuration in children...
  21. ncbi request reprint PCA-derived factors that may be predictive of postoperative pain in pediatric patients: a possible role for the PCA ratio
    Conor McDonnell
    Department of Anesthesia and Pain Medicine, Hospital for Sick Children, University of Toronto, Toronto, Ontario
    J Opioid Manag 8:39-44. 2012
    ..The authors hypothesized that data derived from patient-controlled analgesia (PCA) pumps (specifically the ratio of patient demands to pump deliveries) may predict which patients would develop severe pain after scoliosis repair...
  22. ncbi request reprint Plasma cyclic guanosine 3',5'-monophosphate levels: a marker of glutamate-nitric oxide-guanyl cyclase activity?
    Thomas Engelhardt
    Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, Ontario, Canada
    J Opioid Manag 7:462-6. 2011
    ....
  23. doi request reprint Effectiveness of preoperative screening for sickle cell disease in a population with a newborn screening program: a cohort study
    James D O'Leary
    Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, ON, Canada
    Can J Anaesth 60:54-9. 2013
    ..The primary objective of this study was to determine the effectiveness of selective preoperative screening for SCD based on at-risk ethnicity in Ontario, a region that has a universal newborn sickle hemoglobinopathy screening program...
  24. doi request reprint Coadministration of propofol and remifentanil for lumbar puncture in children: dose-response and an evaluation of two dose combinations
    Jason A Hayes
    Department of Anesthesia, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
    Anesthesiology 109:613-8. 2008
    ..The authors undertook a two-part study to evaluate coadministration of propofol and remifentanil as an anesthetic technique for lumbar puncture in children...
  25. ncbi request reprint A pilot study of the rectus sheath block for pain control after umbilical hernia repair
    Lisa A Isaac
    Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
    Paediatr Anaesth 16:406-9. 2006
    ..In this pilot study, we compared the efficacy of the rectus sheath block with that of our current standard practice--local anesthetic infiltration into the surgical wound--for pain control after umbilical hernia repair in children...
  26. ncbi request reprint Near-miss injection of an anesthetic agent into a cerebrospinal fluid external ventricular drain: special report
    James M Drake
    Division of Neurosurgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Neurosurgery 56:E1161; discussion E1161. 2005
    ..One method of error prevention is the reporting of a near-miss event. We report that intravenous anesthetic agents were nearly injected into the external ventricular drainage (EVD) of a patient during an emergency shunt procedure...
  27. doi request reprint Major complications related to epidural analgesia in children: a 15-year audit of 3,152 epidurals
    Gail K Wong
    Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON, M5G 1X8, Canada
    Can J Anaesth 60:355-63. 2013
    ..We sought to determine the incidence of major complications with the use of continuous epidural analgesia that occurred in our centre over the past 15 years and to describe the nature of these complications...
  28. ncbi request reprint Complete upper airway obstruction after induction of anesthesia in a child with undiagnosed lingual tonsil hypertrophy
    Mauro Arrica
    Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
    Paediatr Anaesth 16:584-7. 2006
    ..More frequently described in adults than in children, LTH can complicate mask ventilation, intubation or both, with the potential for catastrophic consequences...
  29. doi request reprint Carnitine deficiency increases susceptibility to bupivacaine-induced cardiotoxicity in rats
    Gail K Wong
    Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Anesthesiology 114:1417-24. 2011
    ..The authors hypothesized that carnitine deficiency increases susceptibility to bupivacaine-induced asystole in rats and that acute repletion with L-carnitine reverses this effect...
  30. doi request reprint Review article: reporting guidelines in the biomedical literature
    James D O'Leary
    Department of Anesthesia and Pain Medicine, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON, M5G 1X8, Canada
    Can J Anaesth 60:813-21. 2013
    ....
  31. doi request reprint Phasic Genioglossus and Palatoglossus Muscle Activity during Recovery from Sevoflurane Anesthesia: A Prospective Observational Study in Children
    Ilavajady Srinivasan
    Lecturer, Department of Anesthesia and Pain Medicine, Associate Neurophysiologist, Division of Neurosurgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada Associate Professor and Anesthesiologist in Chief, Curtis Joseph and Harold Groves Chair in Pediatric Anesthesia and Pain Medicine, Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto
    Anesthesiology 119:562-8. 2013
    ..The authors tested the hypothesis that phasic inspiratory genioglossus and palatoglossus activity increases during recovery from sevoflurane anesthesia in a dose-dependent manner in children...
  32. doi request reprint Cardiovascular MRI without sedation or general anesthesia using a feed-and-sleep technique in neonates and infants
    Jonathan Windram
    Department of Diagnostic Imaging, Hospital for Sick Children, 555 University Ave, Toronto, Canada M5G 1X8
    Pediatr Radiol 42:183-7. 2012
    ..MRI in small children generally necessitates the use of general anesthesia...
  33. doi request reprint Bibliographic characteristics of the research output of pediatric anesthesiologists in Canada
    James D O'Leary
    The Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, ON, Canada
    Can J Anaesth 57:573-7. 2010
    ..Although described initially for physical sciences, h-indices are being used to assess research productivity and impact in other disciplines...