Research Topics
| Leonardo R BrandaoSummaryAffiliation: The Hospital for Sick Children Country: Canada Publications
| Collaborators
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Detail Information
Publications
The use of elastic compression stockings for post-thrombotic syndrome in a childTina T Biss
Department of Haematology Oncology, The Hospital for Sick Children, Toronto, ON, Canada
Pediatr Blood Cancer 53:462-3. 2009..The presented case highlights the subtle nature of symptoms, potential benefits and limitations of ECS use for PTS, and current lack of evidence in children...
Exercise-induced deep vein thrombosis of the upper extremity. 1. Literature reviewLeonardo R Brandao
Division of Haematology Oncology, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ont, Canada
Acta Haematol 115:214-20. 2006..Similarly, the best therapeutic option has not been established and in the lack of evidence-based guidelines, treatment may be extremely challenging especially in children, in whom long-term complications can be particularly disabling...
Neonatal renal vein thrombosisLeonardo R Brandao
Department of Pediatrics, Division of Haematology Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada
Semin Fetal Neonatal Med 16:323-8. 2011..Long term cohort studies and randomized trials may be helpful to clarify the impact of acute versus prolonged antithrombotic therapy for reducing the morbidity that is associated with neonatal RVT...
Pulmonary embolism in childrenLeonardo R Brandao
Department of Paediatrics, Division of Haematology Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada
Semin Thromb Hemost 37:772-85. 2011..Additionally, a section with the diagnostic tools pertaining to children is included. Closing remarks encompass commentaries related to therapy and outcomes, reflecting on current knowledge gaps related to PE in children...
Exercise-induced deep vein thrombosis of the upper extremity. 2. A case series in childrenLeonardo R Brandao
Division of Haematology Oncology, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ont, Canada
Acta Haematol 115:221-9. 2006..Adolescents with UEDVT treated only with anticoagulation seem to have a poor outcome...
A prospective longitudinal multicenter study of coagulation in pediatric patients undergoing allogeneic stem cell transplantationLeonardo R Brandao
Division of Haematology Oncology, The Hospital for Sick Children, Toronto, Canada
Pediatr Blood Cancer 50:1240-6. 2008..There is little published information in children on the impact of SCT on coagulation, as well as potential correlations between altered coagulation and SCT-associated thrombosis and organ failure...
Thrombotic complications and thromboprophylaxis across all three stages of single ventricle heart palliationCedric Manlhiot
Labatt Family Heart Centre, Department of Pediatrics, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada
J Pediatr 161:513-519.e3. 2012..To describe the incidence of thrombotic complications across all 3 stages of single ventricle palliation and the association between thromboprophylaxis use and thrombotic risk...
Longer blood storage is associated with suboptimal outcomes in high-risk pediatric cardiac surgeryCedric Manlhiot
Labatt Family Heart Centre, Department of Pediatrics, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada
Ann Thorac Surg 93:1563-9. 2012..The negative effects of long-term storage of allogeneic red blood cells (RBCs) on outcomes in adult cardiac surgery have been established, but evidence of a similar effect in pediatric cardiac surgery is limited...
Heparin brand is associated with postsurgical outcomes in children undergoing cardiac surgeryColleen E Gruenwald
Labatt Family Heart Centre, The Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada
Ann Thorac Surg 93:878-82. 2012....
Long-term anticoagulation in Kawasaki disease: Initial use of low molecular weight heparin is a viable option for patients with severe coronary artery abnormalitiesCedric Manlhiot
Division of Cardiology, Department of Pediatrics, University of Toronto, Labatt Family Heart Centre, The Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada
Pediatr Cardiol 31:834-42. 2010..03) but not for those on warfarin (P = 0.55). This study suggests that LMWH is a potentially viable alternative for patients, especially young ones, with severe coronary artery involvement after KD...
Safety of anticoagulants in children with arterial ischemic strokeTal Schechter
Division of Hematology Oncology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Blood 119:949-56. 2012..3507). We conclude that ACT is relatively safe in children with AIS, with a 4% risk of symptomatic ICH. Based on the safety of ACT in our study, clinical trials of ACT in childhood AIS are warranted...
Risk, clinical features, and outcomes of thrombosis associated with pediatric cardiac surgeryCedric Manlhiot
The Hospital for Sick Children, 555 University Avenue, Toronto, ON, Canada M5G 1X8
Circulation 124:1511-9. 2011..Thrombosis, usually considered a serious but rare complication of pediatric cardiac surgery, has not been a major clinical and/or research focus in the past...
A reliable and safe method of collecting blood samples from implantable central venous catheters for determination of plasma gentamicin concentrationsJennifer Chen
Department of Pharmacy, The Hospital for Sick Children, Toronto, Ontario, Canada
Pharmacotherapy 31:776-84. 2011....
Thrombotic events after pediatric liver transplantationChee Yee Ooi
SickKids Transplant Centre, Toronto, ON, Canada
Pediatr Transplant 14:476-82. 2010..In conclusion, the incidence of early TE post-pediatric LT was 16%, including DVT in 8%. Prospective studies are necessary to evaluate the role of prophylactic anticoagulation and potential modifiable risk factors post-pediatric LT...
Clinical features and outcome of pulmonary embolism in childrenTina T Biss
Department of Hematology Oncology, The Hospital for Sick Children, Toronto, ON, Canada
Br J Haematol 142:808-18. 2008..Risk factors for PE in children are distinct from adults and morbidity and mortality is significant. Multicentre prospective studies are required to determine optimal treatment and long-term outcome of childhood PE...
Sonography of renal venous thrombosis in neonates and infants: can we predict outcome?Jeannette K Kraft
Department of Diagnostic Imaging, The Hospital for Sick Children, 555 University Ave, Toronto, ON, M5G 1X8, Canada
Pediatr Radiol 41:299-307. 2011..The relationship between sonographic features of renal venous thrombosis (RVT) and outcome has not been described in a large series of patients...
Management of myocardial infarction in children with Kawasaki diseaseNethnapha Paredes
Thrombosis and Atherosclerosis Research Institute TaARI, Hamilton General Hospital Campus, McMaster University, Hamilton, Ontario, Canada
Blood Coagul Fibrinolysis 21:620-31. 2010..This review provides a summary of the available data on the management of children with Kawasaki disease suffering from myocardial infarction or thrombotic complications that can potentially lead to myocardial infarction...
Idiopathic suppurative pylephlebitis: interventional radiological diagnosis and managementConor O Bogue
Division of Image Guided Therapy, Department of Diagnostic Imaging, The Hospital for Sick Children, The University of Toronto, 555 University Avenue, Toronto, ON, M5G 1X8, Canada
Cardiovasc Intervent Radiol 32:1304-7. 2009..Our aim is to increase the awareness of this entity and stress the importance of early diagnosis and appropriate therapy...
Management and monitoring of anticoagulation for children undergoing cardiopulmonary bypass in cardiac surgeryColleen E Gruenwald
Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, Canada
J Extra Corpor Technol 42:9-19. 2010..However, this review article clearly establishes that further studies are necessary to obtain evidence-based protocols for the proper management of anticoagulation of children undergoing cardiopulmonary bypass...
The role of prothrombotic factors in the ocular manifestations of abusive and non-abusive head trauma: a feasibility studyAnna Yu
Institute of Medical Science, University of Toronto, Toronto, Canada
Child Abuse Negl 36:333-41. 2012..Our objective was to determine whether the hypothesis that prothrombotic factors affect specificity of retinal hemorrhage to AHT can be tested. This may have important ramifications both for diagnosis and expert witness testimony...
Neonatal and childhood right atrial thrombosis: recognition and a risk-stratified treatment approachJanet Yk Yang
Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
Blood Coagul Fibrinolysis 21:301-7. 2010..Systemic anticoagulation therapy should be given to all high-risk or symptomatic RAT patients. Surgical thrombectomy or thrombolytic therapy carries significant risk and should be considered individually...
