M A Tarnopolsky

Summary

Country: Canada

Publications

  1. ncbi Sex differences in carbohydrate metabolism
    M A Tarnopolsky
    Department of Medicine, McMaster University Medical Centre, McMaster University, Hamilton, Ontario, Canada
    Curr Opin Clin Nutr Metab Care 4:521-6. 2001
  2. ncbi Postexercise protein-carbohydrate and carbohydrate supplements increase muscle glycogen in men and women
    M A Tarnopolsky
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada L8S 4K1
    J Appl Physiol 83:1877-83. 1997
  3. ncbi Short-term 17-beta-estradiol administration does not affect metabolism in young males
    M A Tarnopolsky
    Department of Neurology, McMaster University, Hamilton, Ont, Canada
    Int J Sports Med 22:175-80. 2001
  4. ncbi Low glycogen and branched-chain amino acid ingestion do not impair anaplerosis during exercise in humans
    M J Gibala
    Departments of Kinesiology and Medicine, McMaster University, Hamilton, Ontario L8S 4K1
    J Appl Physiol 87:1662-7. 1999
  5. ncbi Creatine-dextrose and protein-dextrose induce similar strength gains during training
    M A Tarnopolsky
    Department of Medicine Neurology and Neurological Rehabilitation, Rm 4U4, McMaster University Medical Center, 1200 Main Street W, Hamilton, Ontario, Canada, L8N 3Z5
    Med Sci Sports Exerc 33:2044-52. 2001
  6. ncbi Short-term 17beta-estradiol decreases glucose R(a) but not whole body metabolism during endurance exercise
    S Carter
    Rehabilitation, McMaster University, Hamilton, Ontario, Canada
    J Appl Physiol 90:139-46. 2001
  7. ncbi Myofibrillar disruption following acute concentric and eccentric resistance exercise in strength-trained men
    M J Gibala
    Department of Kinesiology Neurology and Neurological Rehabilitation, McMaster University, Hamilton, ON, Canada
    Can J Physiol Pharmacol 78:656-61. 2000
  8. ncbi Substrate utilization during endurance exercise in men and women after endurance training
    S L Carter
    Rehabilitation, Department of Medicine, McMaster University, Hamilton, Ontario L8N 3Z5, Canada
    Am J Physiol Endocrinol Metab 280:E898-907. 2001
  9. pmc Myoadenylate deaminase deficiency does not affect muscle anaplerosis during exhaustive exercise in humans
    M A Tarnopolsky
    Department of Medicine and Kinesiology, McMaster University, Hamilton, Ontario, Canada
    J Physiol 533:881-9. 2001
  10. pmc Gene expression profiling in human skeletal muscle during recovery from eccentric exercise
    D J Mahoney
    Department of Medical Sciences, McMaster University Medical Center, 1200 Main Street W, Hamilton, Ontario, Canada
    Am J Physiol Regul Integr Comp Physiol 294:R1901-10. 2008

Collaborators

Detail Information

Publications28

  1. ncbi Sex differences in carbohydrate metabolism
    M A Tarnopolsky
    Department of Medicine, McMaster University Medical Centre, McMaster University, Hamilton, Ontario, Canada
    Curr Opin Clin Nutr Metab Care 4:521-6. 2001
    ..Sex differences in carbohydrate metabolism may have future implications for the care of patients with diabetes and inborn errors of lipid metabolism...
  2. ncbi Postexercise protein-carbohydrate and carbohydrate supplements increase muscle glycogen in men and women
    M A Tarnopolsky
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada L8S 4K1
    J Appl Physiol 83:1877-83. 1997
    ..5 mmol . kg dry muscle-1 . h-1; P < 0.001) with no gender differences. We conclude that postexercise CHO and CHO-Pro-Fat nutritional supplements can increase glycogen resynthesis to a greater extent than Pl for both men and women...
  3. ncbi Short-term 17-beta-estradiol administration does not affect metabolism in young males
    M A Tarnopolsky
    Department of Neurology, McMaster University, Hamilton, Ont, Canada
    Int J Sports Med 22:175-80. 2001
    ..3 --> POST = 237.9; PL-PRE = 582.2 --> POST = 262.4 mmol.kg(-1) [dm]). We concluded that short-term E2 treatment increased plasma E2 to female follicular levels in males but had no effect upon lipid or carbohydrate metabolism...
  4. ncbi Low glycogen and branched-chain amino acid ingestion do not impair anaplerosis during exercise in humans
    M J Gibala
    Departments of Kinesiology and Medicine, McMaster University, Hamilton, Ontario L8S 4K1
    J Appl Physiol 87:1662-7. 1999
    ..Moreover, it appears that low resting glycogen per se does not impair the increase in TCAI during moderate exercise...
  5. ncbi Creatine-dextrose and protein-dextrose induce similar strength gains during training
    M A Tarnopolsky
    Department of Medicine Neurology and Neurological Rehabilitation, Rm 4U4, McMaster University Medical Center, 1200 Main Street W, Hamilton, Ontario, Canada, L8N 3Z5
    Med Sci Sports Exerc 33:2044-52. 2001
    ..We have recently shown that timing of nutrient delivery in the postexercise period can have positive effects on whole body protein turnover (B. D. Roy et al., Med Sci Sports Exerc. 32(8):1412-1418, 2000)...
  6. ncbi Short-term 17beta-estradiol decreases glucose R(a) but not whole body metabolism during endurance exercise
    S Carter
    Rehabilitation, McMaster University, Hamilton, Ontario, Canada
    J Appl Physiol 90:139-46. 2001
    ..05) during exercise after E(2) administration. We concluded that short-term oral E(2) administration decreased glucose R(a) and R(d), maintained plasma glucose homeostasis, but had no effect on substrate oxidation during exercise in men...
  7. ncbi Myofibrillar disruption following acute concentric and eccentric resistance exercise in strength-trained men
    M J Gibala
    Department of Kinesiology Neurology and Neurological Rehabilitation, McMaster University, Hamilton, ON, Canada
    Can J Physiol Pharmacol 78:656-61. 2000
    ..Moreover, it appears that fibre disruption induced by habitual weightlifting exercise is essentially repaired after 5 days of inactivity in trained men...
  8. ncbi Substrate utilization during endurance exercise in men and women after endurance training
    S L Carter
    Rehabilitation, Department of Medicine, McMaster University, Hamilton, Ontario L8N 3Z5, Canada
    Am J Physiol Endocrinol Metab 280:E898-907. 2001
    ..Furthermore, endurance training resulted in a decrease in glucose flux at both ABS and REL exercise intensities after endurance exercise training...
  9. pmc Myoadenylate deaminase deficiency does not affect muscle anaplerosis during exhaustive exercise in humans
    M A Tarnopolsky
    Department of Medicine and Kinesiology, McMaster University, Hamilton, Ontario, Canada
    J Physiol 533:881-9. 2001
    ..4. In summary, complete and partial muscle AMPD deficiency did not affect TCA cycle anaplerosis, phosphocreatine hydrolysis, energy charge or exercise performance...
  10. pmc Gene expression profiling in human skeletal muscle during recovery from eccentric exercise
    D J Mahoney
    Department of Medical Sciences, McMaster University Medical Center, 1200 Main Street W, Hamilton, Ontario, Canada
    Am J Physiol Regul Integr Comp Physiol 294:R1901-10. 2008
    ....
  11. ncbi Gender differences in carbohydrate loading are related to energy intake
    M A Tarnopolsky
    Departments of Medicine Neurology and Rehabilitation, McMaster University, Hamilton, Ontario L8N 3Z5
    J Appl Physiol 91:225-30. 2001
    ..05). There were no gender differences in the proportion of pro- and macroglycogen or hexokinase activity. A low energy intake may explain the previously reported lower capacity for women to glycogen load compared with men...
  12. doi Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men
    Yifan Yang
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON, Canada L8S 4K1
    Br J Nutr 108:1780-8. 2012
    ..These data suggest that, in contrast to younger adults, in whom post-exercise rates of MPS are saturated with 20 g of protein, exercised muscles of older adults respond to higher protein doses...
  13. ncbi Protein and physical performance
    M A Tarnopolsky
    Department of Neurology Neurological Rehabilitation, McMaster University Medical Center, Hamilton, Ontario, Canada
    Curr Opin Clin Nutr Metab Care 2:533-7. 1999
    ..Exercise and nutritional interventions may positively influence the negative effects of aging upon protein metabolism...
  14. ncbi Selective serotonin reuptake inhibitors: Their effect on high-intensity exercise performance
    G Parise
    Departments of Kinesiology and Medicine, McMaster University, Hamilton, Ont, Canada
    Arch Phys Med Rehabil 82:867-71. 2001
    ..05); however, there were no treatment affects on any of the other measurements. CONCLUSION: Acute and chronic SSRI intake does not effect strength or high-intensity exercise performance in young adult men...
  15. ncbi Potential benefits of creatine monohydrate supplementation in the elderly
    M A Tarnopolsky
    Dept of Neurology Neurological Rehabilitation, McMaster University Medical Center, Hamilton, Ontario, Canada
    Curr Opin Clin Nutr Metab Care 3:497-502. 2000
    ....
  16. ncbi Expression of MCT1 and MCT4 in a patient with mitochondrial myopathy
    S K Baker
    Departments of Medicine, Hamilton Health Sciences Corporation, McMaster University Medical Centre, Hamilton, Ontario, L8N 3Z5, Canada
    Muscle Nerve 24:394-8. 2001
    ..These findings support previous work suggesting that the major role of MCT4 is to defend intracellular pH by extruding lactate and H(+) to the interstitium. The role of MCT1 in MM is less clear...
  17. ncbi Creatine transporter and mitochondrial creatine kinase protein content in myopathies
    M A Tarnopolsky
    Department of Medicine Neurology and Rehabilitation, Room 4U4, McMaster University, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
    Muscle Nerve 24:682-8. 2001
    ..This further supports the belief that creatine monohydrate supplementation may benefit patients with low muscle creatine stores, although the reduction in creatine transporter protein may have implications for dosing...
  18. ncbi Effects of acute creatine monohydrate supplementation on leucine kinetics and mixed-muscle protein synthesis
    G Parise
    Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada L8N 3Z5
    J Appl Physiol 91:1041-7. 2001
    ..CrM did not increase total body mass or fat-free mass. We conclude that short-term CrM supplementation may have anticatabolic actions in some proteins (in men), but CrM does not increase whole body or mixed-muscle protein synthesis...
  19. ncbi Cellular adaptation to repeated eccentric exercise-induced muscle damage
    N Stupka
    Department of Kinesiology, Exercise Metabolism Research Group, McMaster University, Hamilton, Ontario, Canada L8S 4K1
    J Appl Physiol 91:1669-78. 2001
    ..05), with a greater increase after bout 2. We conclude that adaptations to eccentric exercise are associated with attenuated serum CK activity and, potentially, an increase in the activity of the ubiquitin proteosome proteolytic pathway...
  20. ncbi Validity of predicting mean arterial blood pressure during exercise
    J D MacDougall
    Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    Med Sci Sports Exerc 31:1876-9. 1999
    ..Our purpose was to test this by directly measuring blood pressure over a wide range of exercise intensities...
  21. doi Mitochondrial DNA shifting in older adults following resistance exercise training
    M A Tarnopolsky
    Department of Pediatrics and Medicine, McMaster University, Hamilton, ON L8N 3Z5, Canada
    Appl Physiol Nutr Metab 34:348-54. 2009
    ..Preliminary data strongly suggest that mitochondrial DNA shifting occurs in skeletal muscle from older adults following resistance-exercise training...
  22. doi The mitochondrial cocktail: rationale for combined nutraceutical therapy in mitochondrial cytopathies
    M A Tarnopolsky
    Department of Pediatrics and Medicine, McMaster University, 1200 Main St W, HSC 2H26, Hamilton, Ontario L8N3Z5, Canada
    Adv Drug Deliv Rev 60:1561-7. 2008
    ....
  23. doi Creatine as a therapeutic strategy for myopathies
    M A Tarnopolsky
    Department of Pediatrics and Medicine, McMaster University, 1200 Main St West, Hamilton, Ontario, Canada
    Amino Acids 40:1397-407. 2011
    ..e., corticosteroids)...
  24. ncbi Post exercise hypotension is sustained during subsequent bouts of mild exercise and simulated activities of daily living
    J R MacDonald
    Department of Kinesiology, McMaster University, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
    J Hum Hypertens 15:567-71. 2001
    ..Although the duration of this relative hypotension needs to be determined, acute exercise may serve as a non-pharmacological aid in the treatment of hypertension...
  25. ncbi An acute oral dose of caffeine does not alter glucose kinetics during prolonged dynamic exercise in trained endurance athletes
    B D Roy
    Dept. of Medicine, McMaster University, Hamilton, ON, Canada
    Eur J Appl Physiol 85:280-6. 2001
    ..However, CAF did lead to elevated plasma lactate concentrations. The exact mechanism of the increase in plasma lactate concentrations remains to be determined...
  26. doi Resistance exercise enhances mTOR and MAPK signalling in human muscle over that seen at rest after bolus protein ingestion
    D R Moore
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada
    Acta Physiol (Oxf) 201:365-72. 2011
    ..We hypothesized that the underlying mechanism for this would be a greater and prolonged phosphorylation of signalling involved in protein translation...
  27. ncbi Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise
    D J Mahoney
    Department of Medical Sciences, McMaster University, Hamilton, Ontario, Canada
    FASEB J 19:1498-500. 2005
    ....
  28. ncbi Potential for creatine and other therapies targeting cellular energy dysfunction in neurological disorders
    M A Tarnopolsky
    Department of Neurology, McMaster University, Hamilton, Ontario, Canada
    Ann Neurol 49:561-74. 2001
    ..These compounds are widely used as dietary supplements; however, they must be subjected to rigorous evaluation through randomized, double-blinded trials to establish efficacy, cost-effectiveness and safety in neurological disorders...