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Genomes and GenesSpecies | M A TarnopolskySummaryCountry: Canada Publications
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Publications
Sex differences in carbohydrate metabolismM A Tarnopolsky
Department of Medicine, McMaster University Medical Centre, McMaster University, Hamilton, Ontario, Canada
Curr Opin Clin Nutr Metab Care 4:521-6. 2001..Sex differences in carbohydrate metabolism may have future implications for the care of patients with diabetes and inborn errors of lipid metabolism...- Postexercise protein-carbohydrate and carbohydrate supplements increase muscle glycogen in men and womenM A Tarnopolsky
Department of Medicine, McMaster University, Hamilton, Ontario, Canada L8S 4K1
J Appl Physiol 83:1877-83. 1997..5 mmol . kg dry muscle-1 . h-1; P < 0.001) with no gender differences. We conclude that postexercise CHO and CHO-Pro-Fat nutritional supplements can increase glycogen resynthesis to a greater extent than Pl for both men and women... - Short-term 17-beta-estradiol administration does not affect metabolism in young malesM A Tarnopolsky
Department of Neurology, McMaster University, Hamilton, Ont, Canada
Int J Sports Med 22:175-80. 2001..3 --> POST = 237.9; PL-PRE = 582.2 --> POST = 262.4 mmol.kg(-1) [dm]). We concluded that short-term E2 treatment increased plasma E2 to female follicular levels in males but had no effect upon lipid or carbohydrate metabolism... - Low glycogen and branched-chain amino acid ingestion do not impair anaplerosis during exercise in humansM J Gibala
Departments of Kinesiology and Medicine, McMaster University, Hamilton, Ontario L8S 4K1
J Appl Physiol 87:1662-7. 1999..Moreover, it appears that low resting glycogen per se does not impair the increase in TCAI during moderate exercise... - Creatine-dextrose and protein-dextrose induce similar strength gains during trainingM A Tarnopolsky
Department of Medicine Neurology and Neurological Rehabilitation, Rm 4U4, McMaster University Medical Center, 1200 Main Street W, Hamilton, Ontario, Canada, L8N 3Z5
Med Sci Sports Exerc 33:2044-52. 2001..We have recently shown that timing of nutrient delivery in the postexercise period can have positive effects on whole body protein turnover (B. D. Roy et al., Med Sci Sports Exerc. 32(8):1412-1418, 2000)... - Myofibrillar disruption following acute concentric and eccentric resistance exercise in strength-trained menM J Gibala
Department of Kinesiology Neurology and Neurological Rehabilitation, McMaster University, Hamilton, ON, Canada
Can J Physiol Pharmacol 78:656-61. 2000..Moreover, it appears that fibre disruption induced by habitual weightlifting exercise is essentially repaired after 5 days of inactivity in trained men... - Short-term 17beta-estradiol decreases glucose R(a) but not whole body metabolism during endurance exerciseS Carter
Rehabilitation, McMaster University, Hamilton, Ontario, Canada
J Appl Physiol 90:139-46. 2001..05) during exercise after E(2) administration. We concluded that short-term oral E(2) administration decreased glucose R(a) and R(d), maintained plasma glucose homeostasis, but had no effect on substrate oxidation during exercise in men... 
Gene expression profiling in human skeletal muscle during recovery from eccentric exerciseD J Mahoney
Department of Medical Sciences, McMaster University Medical Center, 1200 Main Street W, Hamilton, Ontario, Canada
Am J Physiol Regul Integr Comp Physiol 294:R1901-10. 2008....- Myoadenylate deaminase deficiency does not affect muscle anaplerosis during exhaustive exercise in humansM A Tarnopolsky
Department of Medicine and Kinesiology, McMaster University, Hamilton, Ontario, Canada
J Physiol 533:881-9. 2001..4. In summary, complete and partial muscle AMPD deficiency did not affect TCA cycle anaplerosis, phosphocreatine hydrolysis, energy charge or exercise performance... - Substrate utilization during endurance exercise in men and women after endurance trainingS L Carter
Rehabilitation, Department of Medicine, McMaster University, Hamilton, Ontario L8N 3Z5, Canada
Am J Physiol Endocrinol Metab 280:E898-907. 2001..Furthermore, endurance training resulted in a decrease in glucose flux at both ABS and REL exercise intensities after endurance exercise training... - Gender differences in carbohydrate loading are related to energy intakeM A Tarnopolsky
Departments of Medicine Neurology and Rehabilitation, McMaster University, Hamilton, Ontario L8N 3Z5
J Appl Physiol 91:225-30. 2001..05). There were no gender differences in the proportion of pro- and macroglycogen or hexokinase activity. A low energy intake may explain the previously reported lower capacity for women to glycogen load compared with men... - Protein and physical performanceM A Tarnopolsky
Department of Neurology Neurological Rehabilitation, McMaster University Medical Center, Hamilton, Ontario, Canada
Curr Opin Clin Nutr Metab Care 2:533-7. 1999..Exercise and nutritional interventions may positively influence the negative effects of aging upon protein metabolism... - Expression of MCT1 and MCT4 in a patient with mitochondrial myopathyS K Baker
Departments of Medicine, Hamilton Health Sciences Corporation, McMaster University Medical Centre, Hamilton, Ontario, L8N 3Z5, Canada
Muscle Nerve 24:394-8. 2001..These findings support previous work suggesting that the major role of MCT4 is to defend intracellular pH by extruding lactate and H(+) to the interstitium. The role of MCT1 in MM is less clear... - Creatine transporter and mitochondrial creatine kinase protein content in myopathiesM A Tarnopolsky
Department of Medicine Neurology and Rehabilitation, Room 4U4, McMaster University, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
Muscle Nerve 24:682-8. 2001..This further supports the belief that creatine monohydrate supplementation may benefit patients with low muscle creatine stores, although the reduction in creatine transporter protein may have implications for dosing... - Selective serotonin reuptake inhibitors: Their effect on high-intensity exercise performanceG Parise
Departments of Kinesiology and Medicine, McMaster University, Hamilton, Ont, Canada
Arch Phys Med Rehabil 82:867-71. 2001..05); however, there were no treatment affects on any of the other measurements. CONCLUSION: Acute and chronic SSRI intake does not effect strength or high-intensity exercise performance in young adult men... - Potential benefits of creatine monohydrate supplementation in the elderlyM A Tarnopolsky
Dept of Neurology Neurological Rehabilitation, McMaster University Medical Center, Hamilton, Ontario, Canada
Curr Opin Clin Nutr Metab Care 3:497-502. 2000.... - Validity of predicting mean arterial blood pressure during exerciseJ D MacDougall
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Med Sci Sports Exerc 31:1876-9. 1999..Our purpose was to test this by directly measuring blood pressure over a wide range of exercise intensities... - Cellular adaptation to repeated eccentric exercise-induced muscle damageN Stupka
Department of Kinesiology, Exercise Metabolism Research Group, McMaster University, Hamilton, Ontario, Canada L8S 4K1
J Appl Physiol 91:1669-78. 2001..05), with a greater increase after bout 2. We conclude that adaptations to eccentric exercise are associated with attenuated serum CK activity and, potentially, an increase in the activity of the ubiquitin proteosome proteolytic pathway... - Effects of acute creatine monohydrate supplementation on leucine kinetics and mixed-muscle protein synthesisG Parise
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada L8N 3Z5
J Appl Physiol 91:1041-7. 2001..CrM did not increase total body mass or fat-free mass. We conclude that short-term CrM supplementation may have anticatabolic actions in some proteins (in men), but CrM does not increase whole body or mixed-muscle protein synthesis... - An acute oral dose of caffeine does not alter glucose kinetics during prolonged dynamic exercise in trained endurance athletesB D Roy
Dept. of Medicine, McMaster University, Hamilton, ON, Canada
Eur J Appl Physiol 85:280-6. 2001..However, CAF did lead to elevated plasma lactate concentrations. The exact mechanism of the increase in plasma lactate concentrations remains to be determined... - Post exercise hypotension is sustained during subsequent bouts of mild exercise and simulated activities of daily livingJ R MacDonald
Department of Kinesiology, McMaster University, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
J Hum Hypertens 15:567-71. 2001..Although the duration of this relative hypotension needs to be determined, acute exercise may serve as a non-pharmacological aid in the treatment of hypertension... 
The mitochondrial cocktail: rationale for combined nutraceutical therapy in mitochondrial cytopathiesM A Tarnopolsky
Department of Pediatrics and Medicine, McMaster University, 1200 Main St W, HSC 2H26, Hamilton, Ontario L8N3Z5, Canada
Adv Drug Deliv Rev 60:1561-7. 2008....- Mitochondrial DNA shifting in older adults following resistance exercise trainingM A Tarnopolsky
Department of Pediatrics and Medicine, McMaster University, Hamilton, ON L8N 3Z5, Canada
Appl Physiol Nutr Metab 34:348-54. 2009..Preliminary data strongly suggest that mitochondrial DNA shifting occurs in skeletal muscle from older adults following resistance-exercise training... - Resistance exercise enhances mTOR and MAPK signalling in human muscle over that seen at rest after bolus protein ingestionD R Moore
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada
Acta Physiol (Oxf) 201:365-72. 2011..We hypothesized that the underlying mechanism for this would be a greater and prolonged phosphorylation of signalling involved in protein translation... - Creatine as a therapeutic strategy for myopathiesM A Tarnopolsky
Department of Pediatrics and Medicine, McMaster University, 1200 Main St West, Hamilton, Ontario, Canada
Amino Acids 40:1397-407. 2011..e., corticosteroids)... - Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exerciseD J Mahoney
Department of Medical Sciences, McMaster University, Hamilton, Ontario, Canada
FASEB J 19:1498-500. 2005.... - Potential for creatine and other therapies targeting cellular energy dysfunction in neurological disordersM A Tarnopolsky
Department of Neurology, McMaster University, Hamilton, Ontario, Canada
Ann Neurol 49:561-74. 2001..These compounds are widely used as dietary supplements; however, they must be subjected to rigorous evaluation through randomized, double-blinded trials to establish efficacy, cost-effectiveness and safety in neurological disorders...