Research Topics
Genomes and GenesSpecies | Sheldon TobeSummaryAffiliation: Sunnybrook Health Sciences Centre Country: Canada Publications
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Detail Information
Publications
The impact of job strain and marital cohesion on ambulatory blood pressure during 1 year: the double exposure studySheldon W Tobe
Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Am J Hypertens 20:148-53. 2007..Psychosocial and lifestyle stressors, such as job strain and marital factors, have previously been associated with a sustained increase in blood pressure (BP)...
Hypertension management initiative: qualitative results from implementing clinical practice guidelines in primary care through a facilitated practice programSheldon W Tobe
Division of Nephrology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada Electronic address
Can J Cardiol 29:632-5. 2013..Interprofessional collaboration was improved for physicians and nurses but less so for pharmacists. Greater confidence among the nurses to manage hypertension more independently reduced demands on physician time...
Blood pressure 2 years after a chronic disease management intervention studySheldon Tobe
Sunnybrook Health Sciences Centre, Toronto, ON, M4N 3M5, Canada
Int J Circumpolar Health 69:50-60. 2010..The expectation was that blood pressure would return back to the baseline once the study was completed...
Impact of blood pressure variability on cardiac and cerebrovascular complications in hypertensionPaolo Verdecchia
Clinical Research Unit Preventive Cardiology, Hospital R Silvestrini, Perugia, Italy
Am J Hypertens 20:154-61. 2007..The independent prognostic value of daytime and night-time blood pressure (BP) variability estimated by noninvasive 24-h BP monitoring is unclear...
Amlodipine added to quinapril vs quinapril alone for the treatment of hypertension in diabetes: the Amlodipine in Diabetes (ANDI) trialSheldon Tobe
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
J Clin Hypertens (Greenwich) 9:120-7. 2007..In diabetic hypertensive patients, 20 mg/d quinapril plus 5 mg/d amlodipine besylate was a more effective BP-lowering strategy than monotherapy with 40 mg/d quinapril...
The Canadian Hypertension Education Program - a unique Canadian knowledge translation programSheldon W Tobe
Sunnybrook Health Sciences Centre, Toronto, Ontario
Can J Cardiol 23:551-5. 2007..The mission of the Canadian Hypertension Education Program is to reduce the impact of hypertension on cardiovascular disease in Canada...
The impact of endothelin-1 genetic analysis and job strain on ambulatory blood pressureSheldon W Tobe
Division of Nephrology, Sunnybrook Health Sciences Centre, Toronto, Canada
J Psychosom Res 71:97-101. 2011..Using a well-characterized cohort of participants, the impact of associations between genetic factors and job strain on BP was evaluated...
IMPPACT: Investigation of Medical Professionals and Patients Achieving Control TogetherSheldon W Tobe
Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario
Can J Cardiol 24:205-8. 2008..To determine whether home blood pressure monitoring (HBPM) led to physician-initiated medication titration and improved achievement of target BP levels compared with standard, office-based management...
Heart and Stroke Foundation of Ontario (HSFO) high blood pressure strategy's hypertension management initiative study protocolSheldon W Tobe
Division of Nephrology, Suite A240, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada
BMC Health Serv Res 8:251. 2008....
Resistant hypertensionSheldon W Tobe
Division of Nephrology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada
Can J Cardiol 25:315-7. 2009..Referral to a hypertension specialist is appropriate if blood pressure remains uncontrolled despite therapy with three antihypertensive medications...
DreamTel; Diabetes risk evaluation and management tele-monitoring study protocolSheldon W Tobe
Division of Nephrology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada
BMC Endocr Disord 9:13. 2009..TRIAL REGISTRATION: Protocol NCT00325624...
Outcomes of antiproteinuric RAAS blockade: high-dose compared with dual therapySheldon W Tobe
Sunnybrook Health Sciences Centre, A240, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada
Curr Hypertens Rep 11:345-53. 2009..Practitioners using either of these strategies to manage proteinuria should monitor their patients carefully...
Renal athersosclerotic revascularization evaluation (RAVE study): study protocol of a randomized trial [NCT00127738]Sheldon W Tobe
Departments of Medicine and Radiology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada
BMC Nephrol 8:4. 2007....
Atherosclerotic renovascular diseaseSheldon W Tobe
Sunnybrook and Women s College Health Science Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada
Can J Cardiol 22:623-8. 2006..The management of hypertension involves the use of combinations of antihypertensive agents at doses sufficient to control blood pressure. Medical management also includes aggressive lipid-lowering therapy...
Cardiovascular and renal outcomes with telmisartan, ramipril, or both in people at high renal risk: results from the ONTARGET and TRANSCEND studiesSheldon W Tobe
Division of Nephrology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Circulation 123:1098-107. 2011..We hypothesized that dual therapy would be more effective than monotherapy in patients with low glomerular filtration rate and elevated albuminuria...
Identification and management of cardiometabolic risk in Canada: a position paper by the cardiometabolic risk working group (executive summary)Lawrence A Leiter
St Michael s Hospital, Toronto, Ontario, Canada
Can J Cardiol 27:124-31. 2011..Health care professionals must also consider ethnicity-related risk factors in order to appropriately evaluate all individuals in their diverse patient populations...
Hypertension in diabetes: a call to actionNorman R C Campbell
Department of Medicine, University of Calgary, Calgary, Canada
Can J Cardiol 25:299-302. 2009..Intensive individualized lifestyle modification is recommended to prevent and treat hypertension, dyslipidemia, dysglycemia and other vascular risks in people with diabetes...
A framework for discussion on how to improve prevention, management, and control of hypertension in CanadaNorm Campbell
Department of Medicine, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada
Can J Cardiol 28:262-9. 2012..It is hoped the Framework will stimulate discussion and input for its full intended lifespan 2011-2020. The third phase is to work with individuals and organizations on the priorities set in phase 2...
Update on calcium antagonists and the kidneySheldon Tobe
Division of Nephrology, Sunnybrook and Women s College, Health Sciences Center, University of Toronto, Toronto, Canada
Curr Opin Nephrol Hypertens 12:309-15. 2003....
2009 Canadian Hypertension Education Program recommendations: the scientific summary--an annual updateNorman R C Campbell
Department of Medicine, University of Calgary, Calgary, Canada
Can J Cardiol 25:271-7. 2009....
Impact of job and marital strain on ambulatory blood pressure results from the double exposure studySheldon W Tobe
Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Am J Hypertens 18:1046-51. 2005..Psychosocial stressors such as job strain and marital stress have been associated with a sustained increase in blood pressure (BP)...
Hypertension in dialysis and kidney transplant patientsG V Ramesh Prasad
Division of Nephrology, St Michael s Hospital, University of Toronto, Toronto, Canada
Can J Cardiol 25:309-14. 2009....
Treatment of hypertension in patients with nondiabetic chronic kidney diseaseMarcel Ruzicka
Division of Nephrology, University of Ottawa, Ottawa, Ontario
Can J Cardiol 23:595-601. 2007..In this regard, the CHEP will continue to review and update all its recommendations annually...
Applying the 2005 Canadian Hypertension Education Program recommendations: 5. Therapy for patients with hypertension and diabetes mellitusSheldon Tobe
Division of Nephrology, University of Toronto, Toronto, Ont
CMAJ 173:1154-7. 2005
Comparison of two automated sphygmomanometers for use in the office settingMartin G Myers
Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Blood Press Monit 14:45-7. 2009..To compare readings obtained using two automated blood pressure (BP) recording devices, BpTRU and Omron 907, in a clinical setting...
The 2005 Canadian Hypertension Education Program recommendations for the management of hypertension: part 1- blood pressure measurement, diagnosis and assessment of riskBrenda R Hemmelgarn
Division of Nephrology, University of Calgary, Calgary, Canada
Can J Cardiol 21:645-56. 2005..All recommendations reported in the present paper received at least 95% consensus. These guidelines will continue to be updated annually...
The 2006 Canadian Hypertension Education Program recommendations for the management of hypertension: Part I--Blood pressure measurement, diagnosis and assessment of riskB R Hemmelgarn
Division of Nephrology, University of Calgary, and Foothills Hospital, 1403 29th Street Northwest, Calgary, Alberta, Canada
Can J Cardiol 22:573-81. 2006..To provide updated, evidence-based recommendations for the diagnosis and assessment of adults with high blood pressure...
Conventional versus automated measurement of blood pressure in primary care patients with systolic hypertension: randomised parallel design controlled trialMartin G Myers
Schulich Heart Centre, Department of Medicine, University of Toronto, Toronto, ON, Canada
BMJ 342:d286. 2011..To compare the quality and accuracy of manual office blood pressure and automated office blood pressure using the awake ambulatory blood pressure as a gold standard...
Marital support, spousal contact and the course of mild hypertensionBrian Baker
University Health Network, Department of Psychiatry, University of Toronto, Toronto, Canada
J Psychosom Res 55:229-33. 2003....
The use of calcium antagonists in the treatment of hypertensive persons with kidney diseaseSheldon Tobe
Division of Nephrology, Sunnybrook and Womens College HSC, A240 2075 Bayview Avenue, Toronto, Canada M4N 3M5
Curr Hypertens Rep 4:191-4. 2002....
The natural history of the non-nephrotic membranous nephropathy patientMichelle A Hladunewich
University Health Network, University of Toronto, Toronto, Ontario, Canada
Clin J Am Soc Nephrol 4:1417-22. 2009..Although early studies suggest that patients with idiopathic membranous nephropathy (MGN) and subnephrotic range proteinuria overall do well, these studies were small and follow-up was short or difficult to discern...
New algorithm for the diagnosis of hypertensionMartin G Myers
Division of Cardiology, Sunnybrook and Women s Health Sciences Centre, Toronto, Ontario, Canada
Am J Hypertens 18:1369-74. 2005..Out-of-office BP measurements are recommended, whenever feasible, to minimize both measurement error associated with mercury sphygmomanometry and the white coat effect experienced by some patients...
Improving outcomes in diabetes and chronic kidney disease: the basis for Canadian guidelinesPhilip A McFarlane
St Michael s Hospital, Toronto, Ontario
Can J Cardiol 23:585-90. 2007..In the present article, the studies that have influenced these Canadian guidelines are examined, and areas in which further research is still required are identified...
Angiotensin inhibition in renovascular disease: a population-based cohort studyDaniel G Hackam
Division of Clinical Pharmacology, University of Western Ontario, London, Ontario, Canada
Am Heart J 156:549-55. 2008....
Chronic dialysis and death among survivors of acute kidney injury requiring dialysisRon Wald
Division of Nephrology, St Michael s Hospital, 61 Queen St East, 9 140, Toronto, ON M5C 2T2, Canada
JAMA 302:1179-85. 2009..Severe acute kidney injury among hospitalized patients often necessitates initiation of short-term dialysis. Little is known about the long-term outcome of those who survive to hospital discharge...
Effect of nurse-directed hypertension treatment among First Nations people with existing hypertension and diabetes mellitus: the Diabetes Risk Evaluation and Microalbuminuria (DREAM 3) randomized controlled trialSheldon W Tobe
Division of Nephrology, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ont
CMAJ 174:1267-71. 2006....
Microalbuminuria in diabetes mellitusSheldon W Tobe
Sunnybrook and Women's College Health Sciences Centre, Toronto, ON
CMAJ 167:499-503. 2002
Cardiometabolic risk in Canada: a detailed analysis and position paper by the cardiometabolic risk working groupLawrence A Leiter
Li Ka Shing Knowledge Institute of St Michael s Hospital, Toronto, Ontario, Canada
Can J Cardiol 27:e1-e33. 2011..Health care professionals must also consider risk factors related to ethnicity in order to appropriately evaluate everyone in their diverse patient populations...
Hemodialysis infection prevention with polysporin ointmentCharmaine E Lok
University of Toronto, Toronto, Canada
J Am Soc Nephrol 14:169-79. 2003..The prophylactic application of topical Polysporin Triple antibiotic ointment to the central venous catheter insertion site reduced the rate of infections and was associated with improved survival in hemodialysis patients...
Acute interstitial nephritis due to pantoprazoleAmy Ra
Sunnybrook and Women's College Health Sciences Centre, Toronto, Ontario, Canada
Ann Pharmacother 38:41-5. 2004..CONCLUSIONS: Physicians should be aware that drug-induced AIN can be associated with proton-pump inhibitors. Early detection of this rare adverse reaction may prevent acute renal insufficiency...
Diabetes risk evaluation and microalbuminuria (DREAM) studies: ten years of participatory research with a First Nation's home and community model for type 2 diabetes care in Northern SaskatchewanGeorge Pylypchuk
Sunnybrook Health Science Centre, Toronto, Ontario, Canada
Int J Circumpolar Health 67:190-202. 2008..To review the DREAM studies and the role of participatory research using a Home and Community Care model in treating First Nations diabetes...
The 2007 Canadian Hypertension Education Program recommendations for the management of hypertension: part 1- blood pressure measurement, diagnosis and assessment of riskRaj S Padwal
Division of General Internal Medicine, University of Alberta, Edmonton, Alberta
Can J Cardiol 23:529-38. 2007..To provide updated, evidence-based recommendations for the diagnosis and assessment of adults with hypertension...
The 2008 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 1 - blood pressure measurement, diagnosis and assessment of riskRaj J Padwal
Division of General Internal Medicine, University of Alberta, Edmonton, Canada
Can J Cardiol 24:455-63. 2008..To provide updated, evidence-based recommendations for the diagnosis and assessment of adults with hypertension...
More medications, fewer pills: combination medications for the treatment of hypertensionRichard Lewanczuk
Department of Midicine, University of Alberta, Edmonton, Alberta
Can J Cardiol 23:573-6. 2007..Consequently, in the future, fixed-dose combination formulations are likely to become increasingly used in the treatment of cardiovascular disease...
The 2007 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2 - therapyNadia A Khan
Division of General Internal Medicine, University of British Columbia, Vancouver, British Columbia
Can J Cardiol 23:539-50. 2007..To provide updated, evidence-based recommendations for the prevention and management of hypertension in adults...
The effect of alcohol and gender on ambulatory blood pressure: results from the Baseline Double Exposure studySheldon W Tobe
Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto Canada
Am J Hypertens 19:136-9. 2006..Research has demonstrated that psychosocial and lifestyle factors are associated with sustained increases in blood pressure (BP)...
High normal blood pressure and prehypertension: the debate continuesPeter Bolli
Ambulatory Internal Medicine Teaching Clinic, St Catharines, Ontario
Can J Cardiol 23:581-3. 2007..Besides annual follow-up, the Canadian Hypertension Education Program recommends lifestyle therapy for individuals with high normal blood pressure. Ongoing research will establish whether any further management is required...
