Research Topics
| Mary C TierneySummaryAffiliation: Sunnybrook Health Sciences Centre Country: Canada Publications
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Detail Information
Publications
Intensity of recreational physical activity throughout life and later life cognitive functioning in womenMary C Tierney
Geriatric Research Unit, Brain Sciences, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
J Alzheimers Dis 22:1331-8. 2010..These results support further investigation of the effects of life-long exercise intensity on cognition in later life...
Lifelong estrogen exposure and memory in older postmenopausal womenMary C Tierney
Primary Care Research Unit, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
J Alzheimers Dis 34:601-8. 2013..Replication is required with a larger sample representing a broader cross-section of the aging female population...
Prediction of all-cause dementia using neuropsychological tests within 10 and 5 years of diagnosis in a community-based sampleMary C Tierney
Geriatric Research Unit, Brain Sciences Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
J Alzheimers Dis 22:1231-40. 2010..Regression models were supported with bootstrapping estimates. Neuropsychological tests can accurately predict progression to all-cause dementia within 10 years of diagnosis in a large community-based sample of non-demented participants...
Computerized cognitive assessment in primary care to identify patients with suspected cognitive impairmentMary C Tierney
Geriatric Research Unit, Brain Sciences Program, Sunnybrook Health Sciences Centre, Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada
J Alzheimers Dis 20:823-32. 2010..Thus the existing test batteries show potential for use in primary care but further study is needed to demonstrate their feasibility and effectiveness in this setting...
A randomized double-blind trial of the effects of hormone therapy on delayed verbal recall in older womenMary C Tierney
Brain Sciences, Sunnybrook Health Sciences Centre, Department of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada
Psychoneuroendocrinology 34:1065-74. 2009..HT dose and formulation may have contributed to these beneficial outcomes. Replication is warranted before recommendations can be made in the clinical setting...
Neuropsychological predictors of self-neglect in cognitively impaired older people who live aloneMary C Tierney
Geriatric Research Unit, Sunnybrook Health Sciences Centre, Department of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada
Am J Geriatr Psychiatry 15:140-8. 2007..The authors examined the accuracy of certain neuropsychological tests in the prediction of harm resulting from self-neglect in cognitively impaired seniors who lived alone...
Neuropsychological tests accurately predict incident Alzheimer disease after 5 and 10 yearsMary C Tierney
Geriatric Research Unit, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
Neurology 64:1853-9. 2005..To determine whether neuropsychological tests accurately predict incident Alzheimer disease (AD) after 5 and 10 years in participants of the Canadian Study of Health and Aging (CSHA) who were initially nondemented...
Mild cognitive impairment: an operational definition and its conversion rate to Alzheimer's diseaseDaphne M Geslani
Geriatric Research, Sunnybrook and Women s College Health Sciences Centre, Toronto, Canada
Dement Geriatr Cogn Disord 19:383-9. 2005..We aimed to develop an operational definition of MCI consistent with criteria proposed by the Mayo Alzheimer's Disease Center, and to examine its conversion rate to AD...
Risk factors for harm in cognitively impaired seniors who live alone: a prospective studyMary C Tierney
Geriatric Research Unit, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
J Am Geriatr Soc 52:1435-41. 2004..To identify risk factors for harm due to self-neglect or behaviors related to disorientation in cognitively impaired seniors who live alone that can be used in primary care...
Somatic and affective anxiety symptoms and menopausal hot flashesMiriam A Lermer
Geriatric Research Unit, Brain Sciences, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Menopause 18:129-32. 2011..Because hot flash symptoms are similar to symptoms of somatic anxiety, we wanted to examine the differential contribution of somatic anxiety and affective anxiety to hot flash scores...
Verbal fluency patterns in two subgroups of patients with Alzheimer's diseaseNancy J Fisher
Geriatric Research, Sunnybrook and Women's College Health Sciences Centre, Ontario, Canada
Clin Neuropsychol 18:122-31. 2004..These results support the loss theory in explaining the semantic deficit of LAD, and suggest that retrieval difficulties underlie the fluency problems of RAD...
Risk factors for medication nonadherence in older adults with cognitive impairment who live aloneThulasi Thiruchselvam
Primary Care Research Unit, Sunnybrook Health Sciences Centre, Toronto, Canada
Int J Geriatr Psychiatry 27:1275-82. 2012..The aim of this study was to prospectively examine the influence of cognitive, medical, behavioral, and social risk factors on medication nonadherence in community-dwelling older adults with cognitive impairment...
Effects of cannabis on cognitive function in patients with multiple sclerosisKimia Honarmand
University of Toronto, 27 King s College Circle, Toronto, Ontario, Canada M5S
Neurology 76:1153-60. 2011..Given that MS is associated with cognitive deterioration, the aim of this study was to determine the neuropsychological effects of cannabis use in this population...
Contribution of informant and patient ratings to the accuracy of the mini-mental state examination in predicting probable Alzheimer's diseaseMary C Tierney
Geriatric Research Unit, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Ontario, Canada
J Am Geriatr Soc 51:813-8. 2003..To determine whether the accuracy of the Mini-Mental State Examination (MMSE) in predicting future Alzheimer's disease (AD) could be improved by the addition of patient and informant ratings of cognitive difficulties...
Differential prediction of vascular dementia and Alzheimer's disease in nondemented older adults within 5 years of initial testingPaul W H Brewster
Geriatric Research Unit, Brain Sciences, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Alzheimers Dement 8:528-35. 2012..To determine whether neuropsychological tests and the Hachinski Ischemic Score (HIS) can differentiate incident vascular dementia (VaD) from Alzheimer's disease (AD) in nondemented older adults within 5 years of initial testing...
The validity of the Menopause Specific Quality of Life Questionnaire in older womenSujeetha Kulasingam
Geriatric Research Unit, Neurosciences, Sunnybrook Health Sciences Centre, Canada
Maturitas 60:239-43. 2008..To examine the validity of the Menopause Specific Quality of Life Questionnaire (MENQOL) domains when used with elderly women. We also determined whether MENQOL domain scores were related to depression and cognitive complaints...
Mild cognitive impairmentSerge Gauthier
McGill Center for Studies in Aging, Douglas Hospital, Montreal, Quebec, Canada
Lancet 367:1262-70. 2006..Other definitions and subtypes of mild cognitive impairment need to be studied as potential prodromes of Alzheimer's disease and other types of dementia...
