Research Topics
| Ayal SchafferSummaryAffiliation: Sunnybrook Health Sciences Centre Country: Canada Publications
| Collaborators
|
Detail Information
Publications
The CANMAT task force recommendations for the management of patients with mood disorders and comorbid anxiety disordersAyal Schaffer
Mood and Anxiety Disorders Program, Sunnybrook Health Sciences Centre, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
Ann Clin Psychiatry 24:6-22. 2012..This article is part of a set of Canadian Network for Mood and Anxiety Treatments (CANMAT) Comorbidity Task Force papers...- Randomized, double-blind pilot trial comparing lamotrigine versus citalopram for the treatment of bipolar depressionAyal Schaffer
Mood Disorders Program, Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
J Affect Disord 96:95-9. 2006..The aim of this pilot study was to compare adding a second mood stabilizer or an antidepressant at this treatment decision point... - Differences in prevalence and treatment of bipolar disorder among immigrants: results from an epidemiologic surveyAyal Schaffer
Mood and Anxiety Disorders Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Can J Psychiatry 54:734-42. 2009..To add to the limited data on the prevalence, clinical characteristics, and treatment of bipolar disorder (BD) among immigrants... 
A population-based analysis of distinguishers of bipolar disorder from major depressive disorderAyal Schaffer
Mood and Anxiety Disorders Program, Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Room FG 29 Toronto, Ontario, Canada M4N 3M5
J Affect Disord 125:103-10. 2010..The objective of this study was to identify distinguishers of BD from MDD in a population-based sample...- Correlates of suicidality among patients with psychotic depressionAyal Schaffer
Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Suicide Life Threat Behav 38:403-14. 2008..These findings reinforce the evidence that patients with psychotic depression are at high risk for suicide and underscore the importance of examining correlates of suicidality specific to patients with psychotic depression... - Comparison of antidepressant use between subjects with bipolar disorder and major depressive disorder with or without comorbid anxietyAyal Schaffer
Mood Disorders Program, Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
J Clin Psychiatry 68:1785-92. 2007.... - Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the management of patients with bipolar disorder: consensus and controversiesLakshmi N Yatham
Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada
Bipolar Disord 7:5-69. 2005..These guidelines also discuss issues related to bipolar disorder in women and those with comorbidity and include a section on safety and monitoring... - Community survey of bipolar disorder in Canada: lifetime prevalence and illness characteristicsAyal Schaffer
Sunnybrook and Women s College Health Sciences Center, University of Toronto, Toronto, Ontatrio
Can J Psychiatry 51:9-16. 2006..This study reports on the lifetime prevalence and illness characteristics of bipolar disorder (BD) in a large, representative sample of Canadians... - Bipolar disorder among adolescents and young adults: results from an epidemiological sampleNicole Kozloff
Department of Psychiatry, University of Toronto, Canada
J Affect Disord 125:350-4. 2010..The objective of this study was to measure the lifetime prevalence of BD, and to describe the socio-demographics, comorbidities, and use of mental health services among 15-24-year-olds with BD... - Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2009Lakshmi N Yatham
Department of Psychiatry, University of British Columbia, 2255 Wesbrook Mall, Vancouver, BC V6T 2A1, Canada
Bipolar Disord 11:225-55. 2009..Bipolar II disorder is frequently overlooked in treatment guidelines, but has an important clinical impact on patients' lives. This update provides an expanded look at bipolar II disorder... - The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid substance use disordersSerge Beaulieu
Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
Ann Clin Psychiatry 24:38-55. 2012..Therefore, a review of the available evidence is needed to provide guidance to clinicians facing the challenges of treating patients with comorbid mood disorders and SUDs... - Use of treatment services and pharmacotherapy for bipolar disorder in a general population-based mental health surveyAyal Schaffer
Department of Psychiatry, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Canada
J Clin Psychiatry 67:386-93. 2006..This study examined characteristics of treatment utilization in a large general population-based sample of bipolar subjects... - The sequenced treatment alternatives to relieve depression (STAR*D) trial: a reviewMark Sinyor
Department of Psychiatry, University of Toronto, Toronto, Ontario
Can J Psychiatry 55:126-35. 2010..At a cost of US$35 million over 6 years, STAR*D sought to test the effectiveness both of pharmacotherapy and of cognitive therapy, and to ascertain whether certain treatments are more optimal after one or more failed trials... 
Anxiety as a predictor of treatment outcome in children and adolescents with depressionAmy Cheung
Department of Psychiatry, University of Toronto, Toronto, Canada
J Child Adolesc Psychopharmacol 20:211-6. 2010..The aim of this study was to examine the impact of co-morbid illnesses on treatment outcomes in depressed children and adolescents aged 7-17 who were treated with fluoxetine...- Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013Lakshmi N Yatham
Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada
Bipolar Disord 15:1-44. 2013..Asenapine alone or as adjunctive therapy have been added as third-line options... - The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid personality disordersMichael Rosenbluth
Toronto East General Hospital Day, Treatment Program, East York, Ontario, Canada
Ann Clin Psychiatry 24:56-68. 2012..There is a need for recommendations to assist clinicians in treating these frequently encountered patients... - The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid metabolic disordersRoger S McIntyre
Mood Disorders Psychopharmacology Unit, University Health Network, Departments of Psychiatry and Pharmacology, University of Toronto, Toronto, Ontario, Canada
Ann Clin Psychiatry 24:69-81. 2012..Our group conducted a comprehensive literature review to provide evidence-based recommendations for treating metabolic comorbidity in individuals with major depressive disorder (MDD) and bipolar disorder (BD)... - Factors associated with use of mental health services for depressed and/or suicidal youth aged 15-24Amy Cheung
Health Systems Research and Consulting Unit, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Community Ment Health J 45:300-6. 2009..77, 95% CI 1.14, 2.76), and low income (OR 1.89, 95% CI 1.11, 3.23). The findings suggest differences in the factors associated with mental health service use between youth aged 15-18 and 19-24 with depression and/or suicidality... - Does inclusion of a placebo arm influence response to active antidepressant treatment in randomized controlled trials? Results from pooled and meta-analysesMark Sinyor
Department of Psychiatry, University of Toronto, Ontario, Canada
J Clin Psychiatry 71:270-9. 2010..To determine if the inclusion of a placebo arm and/or the number of active comparators in antidepressant trials influences the response rates of the active medication and/or placebo... - Managing medical and psychiatric comorbidity in individuals with major depressive disorder and bipolar disorderRoger S McIntyre
Mood Disorders Psychopharmacology Unit, University Health Network, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
Ann Clin Psychiatry 24:163-9. 2012..Treating comorbid conditions in patients with mood disorders requires sufficient decision support to inform appropriate treatment... - Substances used in completed suicide by overdose in Toronto: an observational study of coroner's dataMark Sinyor
Department of Psychiatry, University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ontario
Can J Psychiatry 57:184-91. 2012..To identify the substances used by people who die from suicide by overdose in Toronto and to determine the correlates of specific categories of substances used... - Sponsorship, antidepressant dose, and outcome in major depressive disorder: meta-analysis of randomized controlled trialsMark Sinyor
Department of Psychiatry, University of Toronto, Toronto, Canada
J Clin Psychiatry 73:e277-87. 2012..This study aims to determine the relationship between sponsorship and antidepressant dosing and efficacy in randomized controlled trials for major depressive disorder... - Seasonality in a community sample of bipolar, unipolar and control subjectsKaren Shin
Department of Psychiatry, University of Toronto, Canada
J Affect Disord 86:19-25. 2005..Even the non-seasonal bipolar group had as much seasonal fluctuation as the seasonal depression group, which has important implications for the management of bipolar illness... - The burden of obesity among adults with bipolar disorder in the United StatesBenjamin I Goldstein
Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Bipolar Disord 13:387-95. 2011..We therefore examined this topic in a representative epidemiologic sample... - Influence of season and latitude in a community sample of subjects with bipolar disorderAyal Schaffer
Department of Psychiatry, University of Toronto, Mood Disorders Program, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario
Can J Psychiatry 48:277-80. 2003..To report on the prevalence of seasonal bipolar disorder (BD) and the impact of latitude in a community sample in the province of Ontario... - Obesity and the three-year longitudinal course of bipolar disorderBenjamin I Goldstein
aDepartment of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, CanadabDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PAcDepartment of Psychiatry, Columbia University, New York, NY, USA
Bipolar Disord 15:284-93. 2013..By contrast, obesity independently predicts the accumulation of medical conditions among adults with BD. Treatment of obesity could potentially mitigate the psychiatric and medical burden of BD... - Differentiating between Bipolar Disorder types I and II: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)Sivan Bega
Mood and Anxiety Disorders Program, Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
J Affect Disord 138:46-53. 2012..Other putative differences between patients with BD I and II exist and may assist in distinguishing between these two conditions... - Depressive symptoms and alcohol consumption among nonalcoholic depression patients treated with desipramineBenjamin I Goldstein
Department of Psychiatry, University of Toronto, Ontario
Can J Psychiatry 49:859-62. 2004.... - Benzodiazepine use and driving: a meta-analysisMark J Rapoport
Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
J Clin Psychiatry 70:663-73. 2009..The purpose of the present study was to examine the experimental and epidemiologic evidence linking benzodiazepine use to driving impairment... - Effect of antidepressant use on admissions to hospital among elderly bipolar patientsAyal Schaffer
Department of Psychiatry, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Int J Geriatr Psychiatry 21:275-80. 2006..The goal of this study was to examine the association between antidepressant use and hospitalization rate for mania or bipolar depression in a large, community-based sample of elderly bipolar patients... - Pharmacotherapy of alcoholism in patients with co-morbid psychiatric disordersBenjamin I Goldstein
Department of Psychiatry, Sunnybrook and Women's College Health Sciences Centre, University of Toronto, Toronto, Canada
Drugs 66:1229-37. 2006..Effectiveness, safety and tolerability are considered, and directions for future study are discussed... - Evidence review and clinical guidance for the use of ziprasidone in CanadaDavid M Gardner
Department of Psychiatry, Dalhousie University, Halifax, NS, Canada
Ann Gen Psychiatry 12:1. 2013..Key challenges in practice include the need for dosing on a full stomach and managing its early onset adverse effect of restlessness. Addressing these issues are critical to its long-term success... - Utility scores of symptom profiles in major depressionAyal Schaffer
Mood and Anxiety Disorders Program, Department of Psychiatry, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, Canada
Psychiatry Res 110:189-97. 2002..Patients with a current depression were willing to accept a greater risk of death to avoid suffering from lifelong depressive symptoms as compared to patients with a past depression or healthy controls... - Double-blind, placebo-controlled pilot study of mexiletine for acute mania or hypomaniaAyal Schaffer
J Clin Psychopharmacol 25:507-8. 2005