Ayal Schaffer

Summary

Affiliation: Sunnybrook Health Sciences Centre
Country: Canada

Publications

  1. ncbi request reprint The CANMAT task force recommendations for the management of patients with mood disorders and comorbid anxiety disorders
    Ayal Schaffer
    Mood and Anxiety Disorders Program, Sunnybrook Health Sciences Centre, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Ann Clin Psychiatry 24:6-22. 2012
  2. doi request reprint A population-based analysis of distinguishers of bipolar disorder from major depressive disorder
    Ayal Schaffer
    Mood and Anxiety Disorders Program, Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Room FG 29 Toronto, Ontario, Canada M4N 3M5
    J Affect Disord 125:103-10. 2010
  3. ncbi request reprint Differences in prevalence and treatment of bipolar disorder among immigrants: results from an epidemiologic survey
    Ayal Schaffer
    Mood and Anxiety Disorders Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Can J Psychiatry 54:734-42. 2009
  4. doi request reprint Correlates of suicidality among patients with psychotic depression
    Ayal Schaffer
    Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Suicide Life Threat Behav 38:403-14. 2008
  5. ncbi request reprint Comparison of antidepressant use between subjects with bipolar disorder and major depressive disorder with or without comorbid anxiety
    Ayal Schaffer
    Mood Disorders Program, Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    J Clin Psychiatry 68:1785-92. 2007
  6. ncbi request reprint Randomized, double-blind pilot trial comparing lamotrigine versus citalopram for the treatment of bipolar depression
    Ayal Schaffer
    Mood Disorders Program, Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Affect Disord 96:95-9. 2006
  7. doi request reprint Bipolar disorder among adolescents and young adults: results from an epidemiological sample
    Nicole Kozloff
    Department of Psychiatry, University of Toronto, Canada
    J Affect Disord 125:350-4. 2010
  8. ncbi request reprint Community survey of bipolar disorder in Canada: lifetime prevalence and illness characteristics
    Ayal Schaffer
    Sunnybrook and Women s College Health Sciences Center, University of Toronto, Toronto, Ontatrio
    Can J Psychiatry 51:9-16. 2006
  9. ncbi request reprint Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the management of patients with bipolar disorder: consensus and controversies
    Lakshmi N Yatham
    Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada
    Bipolar Disord 7:5-69. 2005
  10. ncbi request reprint The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid substance use disorders
    Serge Beaulieu
    Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
    Ann Clin Psychiatry 24:38-55. 2012

Detail Information

Publications36

  1. ncbi request reprint The CANMAT task force recommendations for the management of patients with mood disorders and comorbid anxiety disorders
    Ayal Schaffer
    Mood and Anxiety Disorders Program, Sunnybrook Health Sciences Centre, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Ann Clin Psychiatry 24:6-22. 2012
    ..This article is part of a set of Canadian Network for Mood and Anxiety Treatments (CANMAT) Comorbidity Task Force papers...
  2. doi request reprint A population-based analysis of distinguishers of bipolar disorder from major depressive disorder
    Ayal Schaffer
    Mood and Anxiety Disorders Program, Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Room FG 29 Toronto, Ontario, Canada M4N 3M5
    J Affect Disord 125:103-10. 2010
    ..The objective of this study was to identify distinguishers of BD from MDD in a population-based sample...
  3. ncbi request reprint Differences in prevalence and treatment of bipolar disorder among immigrants: results from an epidemiologic survey
    Ayal Schaffer
    Mood and Anxiety Disorders Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Can J Psychiatry 54:734-42. 2009
    ..To add to the limited data on the prevalence, clinical characteristics, and treatment of bipolar disorder (BD) among immigrants...
  4. doi request reprint Correlates of suicidality among patients with psychotic depression
    Ayal Schaffer
    Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Suicide Life Threat Behav 38:403-14. 2008
    ..These findings reinforce the evidence that patients with psychotic depression are at high risk for suicide and underscore the importance of examining correlates of suicidality specific to patients with psychotic depression...
  5. ncbi request reprint Comparison of antidepressant use between subjects with bipolar disorder and major depressive disorder with or without comorbid anxiety
    Ayal Schaffer
    Mood Disorders Program, Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    J Clin Psychiatry 68:1785-92. 2007
    ....
  6. ncbi request reprint Randomized, double-blind pilot trial comparing lamotrigine versus citalopram for the treatment of bipolar depression
    Ayal Schaffer
    Mood Disorders Program, Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Affect Disord 96:95-9. 2006
    ..The aim of this pilot study was to compare adding a second mood stabilizer or an antidepressant at this treatment decision point...
  7. doi request reprint Bipolar disorder among adolescents and young adults: results from an epidemiological sample
    Nicole Kozloff
    Department of Psychiatry, University of Toronto, Canada
    J Affect Disord 125:350-4. 2010
    ..The objective of this study was to measure the lifetime prevalence of BD, and to describe the socio-demographics, comorbidities, and use of mental health services among 15-24-year-olds with BD...
  8. ncbi request reprint Community survey of bipolar disorder in Canada: lifetime prevalence and illness characteristics
    Ayal Schaffer
    Sunnybrook and Women s College Health Sciences Center, University of Toronto, Toronto, Ontatrio
    Can J Psychiatry 51:9-16. 2006
    ..This study reports on the lifetime prevalence and illness characteristics of bipolar disorder (BD) in a large, representative sample of Canadians...
  9. ncbi request reprint Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the management of patients with bipolar disorder: consensus and controversies
    Lakshmi N Yatham
    Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada
    Bipolar Disord 7:5-69. 2005
    ..These guidelines also discuss issues related to bipolar disorder in women and those with comorbidity and include a section on safety and monitoring...
  10. ncbi request reprint The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid substance use disorders
    Serge Beaulieu
    Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
    Ann Clin Psychiatry 24:38-55. 2012
    ..Therefore, a review of the available evidence is needed to provide guidance to clinicians facing the challenges of treating patients with comorbid mood disorders and SUDs...
  11. doi request reprint Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2009
    Lakshmi N Yatham
    Department of Psychiatry, University of British Columbia, 2255 Wesbrook Mall, Vancouver, BC V6T 2A1, Canada
    Bipolar Disord 11:225-55. 2009
    ..Bipolar II disorder is frequently overlooked in treatment guidelines, but has an important clinical impact on patients' lives. This update provides an expanded look at bipolar II disorder...
  12. ncbi request reprint Use of treatment services and pharmacotherapy for bipolar disorder in a general population-based mental health survey
    Ayal Schaffer
    Department of Psychiatry, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Canada
    J Clin Psychiatry 67:386-93. 2006
    ..This study examined characteristics of treatment utilization in a large general population-based sample of bipolar subjects...
  13. doi request reprint Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013
    Lakshmi N Yatham
    Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada
    Bipolar Disord 15:1-44. 2013
    ..Asenapine alone or as adjunctive therapy have been added as third-line options...
  14. ncbi request reprint The sequenced treatment alternatives to relieve depression (STAR*D) trial: a review
    Mark Sinyor
    Department of Psychiatry, University of Toronto, Toronto, Ontario
    Can J Psychiatry 55:126-35. 2010
    ..At a cost of US$35 million over 6 years, STAR*D sought to test the effectiveness both of pharmacotherapy and of cognitive therapy, and to ascertain whether certain treatments are more optimal after one or more failed trials...
  15. pmc Anxiety as a predictor of treatment outcome in children and adolescents with depression
    Amy Cheung
    Department of Psychiatry, University of Toronto, Toronto, Canada
    J Child Adolesc Psychopharmacol 20:211-6. 2010
    ..The aim of this study was to examine the impact of co-morbid illnesses on treatment outcomes in depressed children and adolescents aged 7-17 who were treated with fluoxetine...
  16. pmc Obesity and the three-year longitudinal course of bipolar disorder
    Benjamin I Goldstein
    Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Bipolar Disord 15:284-93. 2013
    ..Despite substantial cross-sectional evidence that obesity is associated with an increased medical and psychiatric burden in bipolar disorder (BD), few longitudinal studies have examined this topic...
  17. ncbi request reprint The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid metabolic disorders
    Roger S McIntyre
    Mood Disorders Psychopharmacology Unit, University Health Network, Departments of Psychiatry and Pharmacology, University of Toronto, Toronto, Ontario, Canada
    Ann Clin Psychiatry 24:69-81. 2012
    ..Our group conducted a comprehensive literature review to provide evidence-based recommendations for treating metabolic comorbidity in individuals with major depressive disorder (MDD) and bipolar disorder (BD)...
  18. ncbi request reprint The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid personality disorders
    Michael Rosenbluth
    Toronto East General Hospital Day, Treatment Program, East York, Ontario, Canada
    Ann Clin Psychiatry 24:56-68. 2012
    ..There is a need for recommendations to assist clinicians in treating these frequently encountered patients...
  19. doi request reprint Factors associated with use of mental health services for depressed and/or suicidal youth aged 15-24
    Amy Cheung
    Health Systems Research and Consulting Unit, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Community Ment Health J 45:300-6. 2009
    ..77, 95% CI 1.14, 2.76), and low income (OR 1.89, 95% CI 1.11, 3.23). The findings suggest differences in the factors associated with mental health service use between youth aged 15-18 and 19-24 with depression and/or suicidality...
  20. doi request reprint Does inclusion of a placebo arm influence response to active antidepressant treatment in randomized controlled trials? Results from pooled and meta-analyses
    Mark Sinyor
    Department of Psychiatry, University of Toronto, Ontario, Canada
    J Clin Psychiatry 71:270-9. 2010
    ..To determine if the inclusion of a placebo arm and/or the number of active comparators in antidepressant trials influences the response rates of the active medication and/or placebo...
  21. ncbi request reprint Managing medical and psychiatric comorbidity in individuals with major depressive disorder and bipolar disorder
    Roger S McIntyre
    Mood Disorders Psychopharmacology Unit, University Health Network, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Ann Clin Psychiatry 24:163-9. 2012
    ..Treating comorbid conditions in patients with mood disorders requires sufficient decision support to inform appropriate treatment...
  22. ncbi request reprint Substances used in completed suicide by overdose in Toronto: an observational study of coroner's data
    Mark Sinyor
    Department of Psychiatry, University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ontario
    Can J Psychiatry 57:184-91. 2012
    ..To identify the substances used by people who die from suicide by overdose in Toronto and to determine the correlates of specific categories of substances used...
  23. doi request reprint Sponsorship, antidepressant dose, and outcome in major depressive disorder: meta-analysis of randomized controlled trials
    Mark Sinyor
    Department of Psychiatry, University of Toronto, Toronto, Canada
    J Clin Psychiatry 73:e277-87. 2012
    ..This study aims to determine the relationship between sponsorship and antidepressant dosing and efficacy in randomized controlled trials for major depressive disorder...
  24. pmc The burden of obesity among adults with bipolar disorder in the United States
    Benjamin I Goldstein
    Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Bipolar Disord 13:387-95. 2011
    ..We therefore examined this topic in a representative epidemiologic sample...
  25. ncbi request reprint Seasonality in a community sample of bipolar, unipolar and control subjects
    Karen Shin
    Department of Psychiatry, University of Toronto, Canada
    J Affect Disord 86:19-25. 2005
    ..This study examined seasonality in a community sample of five diagnostic groups: normal subjects, those with non-seasonal depression (NSD), seasonal depression (SD), non-seasonal bipolar disorder (NSBD) and seasonal bipolar disorder (SBD)...
  26. ncbi request reprint Influence of season and latitude in a community sample of subjects with bipolar disorder
    Ayal Schaffer
    Department of Psychiatry, University of Toronto, Mood Disorders Program, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario
    Can J Psychiatry 48:277-80. 2003
    ..To report on the prevalence of seasonal bipolar disorder (BD) and the impact of latitude in a community sample in the province of Ontario...
  27. doi request reprint Differentiating between Bipolar Disorder types I and II: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)
    Sivan Bega
    Mood and Anxiety Disorders Program, Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Affect Disord 138:46-53. 2012
    ..Other putative differences between patients with BD I and II exist and may assist in distinguishing between these two conditions...
  28. ncbi request reprint Depressive symptoms and alcohol consumption among nonalcoholic depression patients treated with desipramine
    Benjamin I Goldstein
    Department of Psychiatry, University of Toronto, Ontario
    Can J Psychiatry 49:859-62. 2004
    ..Similarly, the effect of antidepressant treatment on alcohol consumption in this group is not yet understood. This study focuses on changes in depressive symptoms and alcohol consumption in response to treatment with desipramine...
  29. doi request reprint Benzodiazepine use and driving: a meta-analysis
    Mark J Rapoport
    Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    J Clin Psychiatry 70:663-73. 2009
    ..The purpose of the present study was to examine the experimental and epidemiologic evidence linking benzodiazepine use to driving impairment...
  30. ncbi request reprint Effect of antidepressant use on admissions to hospital among elderly bipolar patients
    Ayal Schaffer
    Department of Psychiatry, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Int J Geriatr Psychiatry 21:275-80. 2006
    ..The goal of this study was to examine the association between antidepressant use and hospitalization rate for mania or bipolar depression in a large, community-based sample of elderly bipolar patients...
  31. ncbi request reprint Characterizing suicide in toronto: an observational study and cluster analysis
    Mark Sinyor
    Psychiatrist, Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario Assistant Professor, Department of Psychiatry, University of Toronto, Toronto, Ontario
    Can J Psychiatry 59:26-33. 2014
    ..Identifying and studying subgroups of suicides may advance our understanding of the heterogeneous nature of suicide and help to inform development of more targeted suicide prevention strategies. ..
  32. ncbi request reprint Pharmacotherapy of alcoholism in patients with co-morbid psychiatric disorders
    Benjamin I Goldstein
    Department of Psychiatry, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Canada
    Drugs 66:1229-37. 2006
    ..Effectiveness, safety and tolerability are considered, and directions for future study are discussed...
  33. doi request reprint Use of mental health telemetry to enhance identification and predictive value of early changes during augmentation treatment of major depression
    Ayal Schaffer
    From the Department of Psychiatry, Sunnybrook Health Sciences Centre Department of Psychiatry, University of Toronto and Centre for Mobile Computing in Mental Health, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    J Clin Psychopharmacol 33:775-81. 2013
    ....
  34. pmc Evidence review and clinical guidance for the use of ziprasidone in Canada
    David M Gardner
    Department of Psychiatry, Dalhousie University, Halifax, NS, Canada
    Ann Gen Psychiatry 12:1. 2013
    ..Key challenges in practice include the need for dosing on a full stomach and managing its early onset adverse effect of restlessness. Addressing these issues are critical to its long-term success...
  35. ncbi request reprint Utility scores of symptom profiles in major depression
    Ayal Schaffer
    Mood and Anxiety Disorders Program, Department of Psychiatry, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, Canada
    Psychiatry Res 110:189-97. 2002
    ..Patients with a current depression were willing to accept a greater risk of death to avoid suffering from lifelong depressive symptoms as compared to patients with a past depression or healthy controls...
  36. ncbi request reprint Double-blind, placebo-controlled pilot study of mexiletine for acute mania or hypomania
    Ayal Schaffer
    J Clin Psychopharmacol 25:507-8. 2005