Sharon Nofech-Mozes

Summary

Affiliation: Sunnybrook Health Sciences Centre
Country: Canada

Publications

  1. ncbi request reprint Prognostic and predictive molecular markers in DCIS: a review
    Sharon Nofech-Mozes
    Department of Pathology, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    Adv Anat Pathol 12:256-64. 2005
  2. doi request reprint Systematic review on hormone receptor testing in breast cancer
    Sharon Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, Canada
    Appl Immunohistochem Mol Morphol 20:214-63. 2012
  3. doi request reprint Cancer care Ontario guideline recommendations for hormone receptor testing in breast cancer
    S Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    Clin Oncol (R Coll Radiol) 24:684-96. 2012
  4. doi request reprint Immunophenotyping of serous carcinoma of the female genital tract
    Sharon Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Mod Pathol 21:1147-55. 2008
  5. doi request reprint Detection of HPV-DNA by a PCR-based method in formalin-fixed, paraffin-embedded tissue from rare endocervical carcinoma types
    Sharon Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Appl Immunohistochem Mol Morphol 18:80-5. 2010
  6. ncbi request reprint Adenomyosis is associated with myometrial invasion by FIGO 1 endometrial adenocarcinoma
    Nadia D Ismiil
    Department of Pathology, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    Int J Gynecol Pathol 26:278-83. 2007
  7. ncbi request reprint Adenomyosis involved by endometrial adenocarcinoma is a significant risk factor for deep myometrial invasion
    Nadia Ismiil
    Department of Pathology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada M4N 3M5
    Ann Diagn Pathol 11:252-7. 2007
  8. ncbi request reprint Endometrial endometrioid adenocarcinoma: a pathologic analysis of 827 consecutive cases
    Sharon Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada M4N 3M5
    Am J Clin Pathol 129:110-4. 2008
  9. doi request reprint Lymphovascular invasion is a significant predictor for distant recurrence in patients with early-stage endometrial endometrioid adenocarcinoma
    Sharon Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Center, Toronto, ON, Canada
    Am J Clin Pathol 129:912-7. 2008
  10. doi request reprint Intraoperative consultation for axillary sentinel lymph node biopsy: an 8-year audit
    Sharon Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Int J Surg Pathol 18:129-37. 2010

Detail Information

Publications26

  1. ncbi request reprint Prognostic and predictive molecular markers in DCIS: a review
    Sharon Nofech-Mozes
    Department of Pathology, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    Adv Anat Pathol 12:256-64. 2005
    ..However, controversies exist regarding the value of these prognostic factors, their interrelationship, and their advantages over morphologic evaluation...
  2. doi request reprint Systematic review on hormone receptor testing in breast cancer
    Sharon Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, Canada
    Appl Immunohistochem Mol Morphol 20:214-63. 2012
    ..Proficiency testing or quality assurance of immunohistochemistry is described...
  3. doi request reprint Cancer care Ontario guideline recommendations for hormone receptor testing in breast cancer
    S Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    Clin Oncol (R Coll Radiol) 24:684-96. 2012
    ..A formal external review was conducted to validate the relevance of these recommendations. It is anticipated that widespread adoption of these guidelines will further improve the accuracy of hormone receptor testing in Canada...
  4. doi request reprint Immunophenotyping of serous carcinoma of the female genital tract
    Sharon Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Mod Pathol 21:1147-55. 2008
    ..HER2/neu was exclusively overexpressed in serous carcinomas of endometrial origin...
  5. doi request reprint Detection of HPV-DNA by a PCR-based method in formalin-fixed, paraffin-embedded tissue from rare endocervical carcinoma types
    Sharon Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Appl Immunohistochem Mol Morphol 18:80-5. 2010
    ..Our observation is particularly significant in cervical cancer prevention as we enter the HPV vaccination era...
  6. ncbi request reprint Adenomyosis is associated with myometrial invasion by FIGO 1 endometrial adenocarcinoma
    Nadia D Ismiil
    Department of Pathology, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    Int J Gynecol Pathol 26:278-83. 2007
    ..When compared with their counterparts that occur in the absence of adenomyosis, these tumors are significantly more likely to invade the myometrium...
  7. ncbi request reprint Adenomyosis involved by endometrial adenocarcinoma is a significant risk factor for deep myometrial invasion
    Nadia Ismiil
    Department of Pathology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada M4N 3M5
    Ann Diagn Pathol 11:252-7. 2007
    ..When compared with tumors that do not involve adenomyosis, these tumors are not only more likely to invade the myometrium but are significantly more prone to achieve deep invasion into the outer half...
  8. ncbi request reprint Endometrial endometrioid adenocarcinoma: a pathologic analysis of 827 consecutive cases
    Sharon Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada M4N 3M5
    Am J Clin Pathol 129:110-4. 2008
    ..0065), and LVI (P > .0001).EEA manifests most commonly with low tumor grade and without deep myometrial invasion. High tumor grade is significantly associated with deep myometrial invasion, cervical involvement, and LVI...
  9. doi request reprint Lymphovascular invasion is a significant predictor for distant recurrence in patients with early-stage endometrial endometrioid adenocarcinoma
    Sharon Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Center, Toronto, ON, Canada
    Am J Clin Pathol 129:912-7. 2008
    ..Multivariate analysis revealed LVI as the only independent predictor for distant recurrence (HR, 2.841; CI, 1.282-6.297). Studies to examine the role of adjuvant systemic therapy in patients with early-stage disease should be considered...
  10. doi request reprint Intraoperative consultation for axillary sentinel lymph node biopsy: an 8-year audit
    Sharon Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Int J Surg Pathol 18:129-37. 2010
    ..Intraoperative consultation via FS for SLNB is a safe practice that can reliably save clinically node-negative patients a second surgery...
  11. ncbi request reprint Significance of multifocality in ductal carcinoma in situ: outcomes of women treated with breast-conserving therapy
    Eileen Rakovitch
    Toronto Sunnybrook Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada
    J Clin Oncol 25:5591-6. 2007
    ..The objective of this study is to evaluate the significance of multifocality and the outcomes of women with multifocal DCIS treated with breast-conserving therapy...
  12. doi request reprint Is routine appendectomy at the time of primary surgery for mucinous ovarian neoplasms beneficial?
    Tomer Feigenberg
    Division of Gynecologic Oncology, University of Toronto, Toronto, Ontario, Canada
    Int J Gynecol Cancer 23:1205-9. 2013
    ..Removal of the appendix in the setting of mucinous histologic type is primarily driven by the existing challenge to distinguish between primary ovarian mucinous neoplasm and metastatic appendiceal carcinoma to the ovary...
  13. doi request reprint Postradical vaginal trachelectomy follow-up by isthmic-vaginal smear cytology: a 13-year audit
    Zeina Ghorab
    Department of Pathology, Sunnybrook Health Sciences Center, Toronto, Ontario, Canada M4N 3M5
    Diagn Cytopathol 37:641-6. 2009
    ..This study summarizes our experience, emphasizing the role of isthmic-vaginal smears for early detection of central recurrence and highlighting the role of LUSEC and reactive changes as potential overcall pitfalls...
  14. doi request reprint Immunohistochemical characterization of primary and recurrent adult granulosa cell tumors
    Sharon Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre and University of Toronto, Toronto, Ontario, Canada
    Int J Gynecol Pathol 31:80-90. 2012
    ....
  15. doi request reprint Intraoperative consultation in gynecologic pathology: a 6-year audit at a tertiary care medical center
    Nadia Ismiil
    Department of Pathology, Sunnybrook Health Sciences Center, Toronto, Ontario, Canada
    Int J Gynecol Cancer 19:152-7. 2009
    ..This study addresses a wide range of quality assurance issues regarding this practice through a comprehensive audit of our experience...
  16. doi request reprint Patterns of recurrence in the basal and non-basal subtypes of triple-negative breast cancers
    Sharon Nofech-Mozes
    Department of Pathology, Sunnybrook Health Sciences Center and University of Toronto, Toronto, ON, Canada
    Breast Cancer Res Treat 118:131-7. 2009
    ..The prognosis of these women may be superior to that of basal-like breast cancers but firm conclusions cannot be made...
  17. ncbi request reprint Intratumoral heterogeneity of HER2/neu in breast cancer--a rare event
    Wedad Hanna
    Department of Pathology, Sunnybrook Health Sciences Center, Toronto, Ontario, Canada
    Breast J 13:122-9. 2007
    ....
  18. doi request reprint Is ductal carcinoma in situ with "possible invasion" more predictive of invasive carcinoma than pure ductal carcinoma in situ?
    Tal Arazi-Kleinman
    Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada
    Can Assoc Radiol J 63:146-52. 2012
    ....
  19. doi request reprint Lymphatic vessel density as a prognostic marker in clinical stage I endocervical adenocarcinoma
    Reda S Saad
    Department of Pathology, Sunnybrook Health Sciences Center University of Toronto, Ontario Canada
    Int J Gynecol Pathol 29:386-93. 2010
    ..Our study showed that both angiogenesis and lymphangiogenesis play an important role in the progression of endocervical adenocarcinoma, and that peritumoral D2-40 LVD is an independent predictor of lymph node metastasis...
  20. doi request reprint Can we select individuals with low risk ductal carcinoma in situ (DCIS)? A population-based outcomes analysis
    Eileen Rakovitch
    Department of Radiation Oncology, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada
    Breast Cancer Res Treat 138:581-90. 2013
    ..The omission of radiotherapy after BCS for DCIS resulted in substantive recurrences that might have been avoided with treatment. Additional markers are needed to identify a low risk group in whom radiation can be safely omitted...
  21. doi request reprint Breast metastasis by medullary thyroid carcinoma detected by FDG positron emission tomography
    Sharon Nofech-Mozes
    Department of Anatomical Pathology, Sunnybrook Health Sciences Center, Toronto, ON, Canada M4N 3M5
    Ann Diagn Pathol 12:67-71. 2008
    ....
  22. doi request reprint Toker cells revisited
    Sharon Nofech-Mozes
    Department of Pathology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Breast J 15:394-8. 2009
    ..The substantial number and the clustering of Toker cells should not be mistaken for PD of the nipple. Unlike PD, Toker cells have small bland nuclei and are characterized by CK7+ and HER2/neu ER and PR negative immunoprofile...
  23. doi request reprint Evaluation of two management strategies for preoperative grade 1 endometrial cancer
    Marcus Q Bernardini
    Division of Gynaecologic Oncology, University Health Network, Toronto, Ontario, Canada
    Obstet Gynecol 114:7-15. 2009
    ..To compare the practices, adjuvant treatment, and outcomes of patients with preoperatively assessed grade 1 endometrioid endometrial cancer between two academic gynecologic oncology centers that use different treatment strategies...
  24. doi request reprint Fine-needle aspiration biopsy of breast adenomyoepithelioma: a potential false positive pitfall and presence of intranuclear cytoplasmic inclusions
    Reda S Saad
    Department of Pathology, Sunnybrook Health Sciences Center University of Toronto, Toronto, ON, Canada
    Diagn Cytopathol 40:1005-9. 2012
    ..Cytopathologists should be familiarized with this entity to avoid a misdiagnosis of carcinoma...
  25. doi request reprint The role of cytokeratin 5/6 as an adjunct diagnostic tool in breast core needle biopsies
    Sharon Nofech-Mozes
    Department of Pathology, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada
    Int J Surg Pathol 16:399-406. 2008
    ..Cytokeratin 5/6 can be a useful adjunct in cases with ductal hyperplasia but not in columnar cell lesions, where it is universally negative...
  26. ncbi request reprint Cyclooxygenase-2 (COX-2) immunostaining does not correlate with the degree of vulvar neoplasia
    Sharon Nofech-Mozes
    Department of Pathology, Sunnybrook and Women s College Health Sciences Centre, Toronto ON, USA
    J Obstet Gynaecol Can 28:290-4. 2006
    ..In the last decade, its biological role has been investigated in various pre-invasive and invasive cancers with the hope that it can serve as a target for cancer prevention and treatment...