Research Topics
Species | Sharon Nofech-MozesSummaryAffiliation: Sunnybrook Health Sciences Centre Country: Canada Publications
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Publications
Prognostic and predictive molecular markers in DCIS: a reviewSharon Nofech-Mozes
Department of Pathology, Sunnybrook and Women's College Health Sciences Center, Toronto, Ontario, Canada
Adv Anat Pathol 12:256-64. 2005..However, controversies exist regarding the value of these prognostic factors, their interrelationship, and their advantages over morphologic evaluation...
Systematic review on hormone receptor testing in breast cancerSharon Nofech-Mozes
Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, Canada
Appl Immunohistochem Mol Morphol 20:214-63. 2012..Proficiency testing or quality assurance of immunohistochemistry is described...- Cancer care ontario guideline recommendations for hormone receptor testing in breast cancerS Nofech-Mozes
Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada Electronic address
Clin Oncol (R Coll Radiol) 24:684-96. 2012..A formal external review was conducted to validate the relevance of these recommendations. It is anticipated that widespread adoption of these guidelines will further improve the accuracy of hormone receptor testing in Canada... - Detection of HPV-DNA by a PCR-based method in formalin-fixed, paraffin-embedded tissue from rare endocervical carcinoma typesSharon Nofech-Mozes
Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Appl Immunohistochem Mol Morphol 18:80-5. 2010..Our observation is particularly significant in cervical cancer prevention as we enter the HPV vaccination era... - Immunophenotyping of serous carcinoma of the female genital tractSharon Nofech-Mozes
Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Mod Pathol 21:1147-55. 2008..HER2/neu was exclusively overexpressed in serous carcinomas of endometrial origin... - Adenomyosis is associated with myometrial invasion by FIGO 1 endometrial adenocarcinomaNadia D Ismiil
Department of Pathology, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
Int J Gynecol Pathol 26:278-83. 2007..When compared with their counterparts that occur in the absence of adenomyosis, these tumors are significantly more likely to invade the myometrium... - Adenomyosis involved by endometrial adenocarcinoma is a significant risk factor for deep myometrial invasionNadia Ismiil
Department of Pathology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada M4N 3M5
Ann Diagn Pathol 11:252-7. 2007..When compared with tumors that do not involve adenomyosis, these tumors are not only more likely to invade the myometrium but are significantly more prone to achieve deep invasion into the outer half... - Endometrial endometrioid adenocarcinoma: a pathologic analysis of 827 consecutive casesSharon Nofech-Mozes
Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada M4N 3M5
Am J Clin Pathol 129:110-4. 2008..0065), and LVI (P > .0001).EEA manifests most commonly with low tumor grade and without deep myometrial invasion. High tumor grade is significantly associated with deep myometrial invasion, cervical involvement, and LVI... - Lymphovascular invasion is a significant predictor for distant recurrence in patients with early-stage endometrial endometrioid adenocarcinomaSharon Nofech-Mozes
Department of Anatomic Pathology, Sunnybrook Health Sciences Center, Toronto, ON, Canada
Am J Clin Pathol 129:912-7. 2008..Multivariate analysis revealed LVI as the only independent predictor for distant recurrence (HR, 2.841; CI, 1.282-6.297). Studies to examine the role of adjuvant systemic therapy in patients with early-stage disease should be considered... - Significance of multifocality in ductal carcinoma in situ: outcomes of women treated with breast-conserving therapyEileen Rakovitch
Toronto Sunnybrook Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada
J Clin Oncol 25:5591-6. 2007..The objective of this study is to evaluate the significance of multifocality and the outcomes of women with multifocal DCIS treated with breast-conserving therapy... - Intraoperative consultation for axillary sentinel lymph node biopsy: an 8-year auditSharon Nofech-Mozes
Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Int J Surg Pathol 18:129-37. 2010..Intraoperative consultation via FS for SLNB is a safe practice that can reliably save clinically node-negative patients a second surgery... - Postradical vaginal trachelectomy follow-up by isthmic-vaginal smear cytology: a 13-year auditZeina Ghorab
Department of Pathology, Sunnybrook Health Sciences Center, Toronto, Ontario, Canada M4N 3M5
Diagn Cytopathol 37:641-6. 2009..This study summarizes our experience, emphasizing the role of isthmic-vaginal smears for early detection of central recurrence and highlighting the role of LUSEC and reactive changes as potential overcall pitfalls... - Immunohistochemical characterization of primary and recurrent adult granulosa cell tumorsSharon Nofech-Mozes
Department of Anatomic Pathology, Sunnybrook Health Sciences Centre and University of Toronto, Toronto, Ontario, Canada
Int J Gynecol Pathol 31:80-90. 2012.... - Intratumoral heterogeneity of HER2/neu in breast cancer--a rare eventWedad Hanna
Department of Pathology, Sunnybrook Health Sciences Center, Toronto, Ontario, Canada
Breast J 13:122-9. 2007.... - Patterns of recurrence in the basal and non-basal subtypes of triple-negative breast cancersSharon Nofech-Mozes
Department of Pathology, Sunnybrook Health Sciences Center and University of Toronto, Toronto, ON, Canada
Breast Cancer Res Treat 118:131-7. 2009..The prognosis of these women may be superior to that of basal-like breast cancers but firm conclusions cannot be made... - Intraoperative consultation in gynecologic pathology: a 6-year audit at a tertiary care medical centerNadia Ismiil
Department of Pathology, Sunnybrook Health Sciences Center, Toronto, Ontario, Canada
Int J Gynecol Cancer 19:152-7. 2009..This study addresses a wide range of quality assurance issues regarding this practice through a comprehensive audit of our experience... - Is ductal carcinoma in situ with "possible invasion" more predictive of invasive carcinoma than pure ductal carcinoma in situ?Tal Arazi-Kleinman
Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada
Can Assoc Radiol J 63:146-52. 2012.... - Lymphatic vessel density as a prognostic marker in clinical stage I endocervical adenocarcinomaReda S Saad
Department of Pathology, Sunnybrook Health Sciences Center University of Toronto, Ontario Canada
Int J Gynecol Pathol 29:386-93. 2010..Our study showed that both angiogenesis and lymphangiogenesis play an important role in the progression of endocervical adenocarcinoma, and that peritumoral D2-40 LVD is an independent predictor of lymph node metastasis... - Can we select individuals with low risk ductal carcinoma in situ (DCIS)? A population-based outcomes analysisEileen Rakovitch
Department of Radiation Oncology, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada
Breast Cancer Res Treat 138:581-90. 2013..The omission of radiotherapy after BCS for DCIS resulted in substantive recurrences that might have been avoided with treatment. Additional markers are needed to identify a low risk group in whom radiation can be safely omitted... - Breast metastasis by medullary thyroid carcinoma detected by FDG positron emission tomographySharon Nofech-Mozes
Department of Anatomical Pathology, Sunnybrook Health Sciences Center, Toronto, ON, Canada M4N 3M5
Ann Diagn Pathol 12:67-71. 2008.... - Toker cells revisitedSharon Nofech-Mozes
Department of Pathology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Breast J 15:394-8. 2009..The substantial number and the clustering of Toker cells should not be mistaken for PD of the nipple. Unlike PD, Toker cells have small bland nuclei and are characterized by CK7+ and HER2/neu ER and PR negative immunoprofile... - Evaluation of two management strategies for preoperative grade 1 endometrial cancerMarcus Q Bernardini
Division of Gynaecologic Oncology, University Health Network, Toronto, Ontario, Canada
Obstet Gynecol 114:7-15. 2009..To compare the practices, adjuvant treatment, and outcomes of patients with preoperatively assessed grade 1 endometrioid endometrial cancer between two academic gynecologic oncology centers that use different treatment strategies... - Fine-needle aspiration biopsy of breast adenomyoepithelioma: a potential false positive pitfall and presence of intranuclear cytoplasmic inclusionsReda S Saad
Department of Pathology, Sunnybrook Health Sciences Center University of Toronto, Toronto, ON, Canada
Diagn Cytopathol 40:1005-9. 2012..Cytopathologists should be familiarized with this entity to avoid a misdiagnosis of carcinoma... - The role of cytokeratin 5/6 as an adjunct diagnostic tool in breast core needle biopsiesSharon Nofech-Mozes
Department of Pathology, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada
Int J Surg Pathol 16:399-406. 2008..Cytokeratin 5/6 can be a useful adjunct in cases with ductal hyperplasia but not in columnar cell lesions, where it is universally negative... - Cyclooxygenase-2 (COX-2) immunostaining does not correlate with the degree of vulvar neoplasiaSharon Nofech-Mozes
Department of Pathology, Sunnybrook and Women's College Health Sciences Centre, Toronto ON, USA
J Obstet Gynaecol Can 28:290-4. 2006..CONCLUSION: COX-2 staining in inflamed, dysplastic, and malignant vulvar epithelium is variable but, as shown in this study, does not correlate with the degree of vulvar dysplasia or malignancy...