Andrew Loblaw

Summary

Affiliation: Sunnybrook Health Sciences Centre
Country: Canada

Publications

  1. doi request reprint Prostate cancer death of men treated with initial active surveillance: clinical and biochemical characteristics
    Yonah Krakowsky
    Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Urol 184:131-5. 2010
  2. ncbi request reprint Dexamethasone for the prophylaxis of radiation-induced pain flare after palliative radiotherapy for bone metastases: a pilot study
    Edward Chow
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Center, University of Toronto, Toronto, Canada
    Support Care Cancer 15:643-7. 2007
  3. doi request reprint Prostate stereotactic ablative body radiotherapy using a standard linear accelerator: toxicity, biochemical, and pathological outcomes
    Andrew Loblaw
    Department of Radiation Oncology, University of Toronto, Canada
    Radiother Oncol 107:153-8. 2013
  4. doi request reprint Systemic therapy in men with metastatic castration-resistant prostate cancer: a systematic review
    D A Loblaw
    Sunnybrook Health Sciences Centre, Odette Cancer Centre, Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 25:406-30. 2013
  5. doi request reprint A 2011 updated systematic review and clinical practice guideline for the management of malignant extradural spinal cord compression
    D Andrew Loblaw
    Department of Radiation Oncology, Sunnybrook Health Science Centre, University of Toronto, Toronto, Canada
    Int J Radiat Oncol Biol Phys 84:312-7. 2012
  6. ncbi request reprint Functional and pharmacokinetic outcomes after a single intravenous infusion of recombinant human erythropoietin in patients with malignant extradural spinal cord compression
    D A Loblaw
    Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 19:63-70. 2007
  7. doi request reprint Comparing prostate specific antigen triggers for intervention in men with stable prostate cancer on active surveillance
    Andrew Loblaw
    Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Urol 184:1942-6. 2010
  8. doi request reprint Malignant extradural spinal cord compression in men with prostate cancer
    Andrew Loblaw
    Department of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Curr Opin Support Palliat Care 5:206-10. 2011
  9. ncbi request reprint The optimal dose fractionation schema for malignant extradural spinal cord compression
    D Andrew Loblaw
    Department of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Canada
    J Support Oncol 9:121-4. 2011
  10. doi request reprint Is single fraction 15 Gy the preferred high dose-rate brachytherapy boost dose for prostate cancer?
    Gerard Morton
    Sunnybrook Odette Cancer Centre, Toronto, Canada
    Radiother Oncol 100:463-7. 2011

Detail Information

Publications32

  1. doi request reprint Prostate cancer death of men treated with initial active surveillance: clinical and biochemical characteristics
    Yonah Krakowsky
    Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Urol 184:131-5. 2010
    ..This is a detailed report of 5 of 453 patients on surveillance who died of prostate cancer...
  2. ncbi request reprint Dexamethasone for the prophylaxis of radiation-induced pain flare after palliative radiotherapy for bone metastases: a pilot study
    Edward Chow
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Center, University of Toronto, Toronto, Canada
    Support Care Cancer 15:643-7. 2007
    ..To investigate the efficacy of dexamethasone as a prophylactic adjuvant analgesic to decrease pain flare and to assess its safety and tolerance of dexamethasone...
  3. doi request reprint Prostate stereotactic ablative body radiotherapy using a standard linear accelerator: toxicity, biochemical, and pathological outcomes
    Andrew Loblaw
    Department of Radiation Oncology, University of Toronto, Canada
    Radiother Oncol 107:153-8. 2013
    ..The objectives are to report the toxicities, biochemical and pathologic outcomes of this prospective study...
  4. doi request reprint Systemic therapy in men with metastatic castration-resistant prostate cancer: a systematic review
    D A Loblaw
    Sunnybrook Health Sciences Centre, Odette Cancer Centre, Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 25:406-30. 2013
    ..This review was undertaken to determine which systemic therapies improve cancer- or patient-related outcomes in men with mCRPC...
  5. doi request reprint A 2011 updated systematic review and clinical practice guideline for the management of malignant extradural spinal cord compression
    D Andrew Loblaw
    Department of Radiation Oncology, Sunnybrook Health Science Centre, University of Toronto, Toronto, Canada
    Int J Radiat Oncol Biol Phys 84:312-7. 2012
    ..To update the 2005 Cancer Care Ontario practice guidelines for the diagnosis and treatment of adult patients with a suspected or confirmed diagnosis of extradural malignant spinal cord compression (MESCC)...
  6. ncbi request reprint Functional and pharmacokinetic outcomes after a single intravenous infusion of recombinant human erythropoietin in patients with malignant extradural spinal cord compression
    D A Loblaw
    Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 19:63-70. 2007
    ..To determine the cerebrospinal fluid concentrations and the functional and pain outcomes after a single intravenous infusion of erythropoietin at the start of a standard radiotherapy and steroid protocol...
  7. doi request reprint Comparing prostate specific antigen triggers for intervention in men with stable prostate cancer on active surveillance
    Andrew Loblaw
    Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Urol 184:1942-6. 2010
    ..We determined the proportion of men with nonprogressive prostate cancer on active surveillance who had a trigger for treatment using various measures of prostate specific antigen kinetics...
  8. doi request reprint Malignant extradural spinal cord compression in men with prostate cancer
    Andrew Loblaw
    Department of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Curr Opin Support Palliat Care 5:206-10. 2011
    ..Treatment needs to be individualized and estimating the prognosis is critical to achieving a balance between effectiveness therapy and the burden of treatment...
  9. ncbi request reprint The optimal dose fractionation schema for malignant extradural spinal cord compression
    D Andrew Loblaw
    Department of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Canada
    J Support Oncol 9:121-4. 2011
    ..Surgery and radiation should be considered for patients with a more positive prognosis. For patients not getting surgery, enrollment in clinical trials of single vs. multiple fractions of radiation should be a priority...
  10. doi request reprint Is single fraction 15 Gy the preferred high dose-rate brachytherapy boost dose for prostate cancer?
    Gerard Morton
    Sunnybrook Odette Cancer Centre, Toronto, Canada
    Radiother Oncol 100:463-7. 2011
    ..Our purpose is to compare outcomes with a single fraction HDR boost to that with a standard fractionated boost in intermediate risk prostate cancer...
  11. ncbi request reprint Effect of androgen suppression on hemoglobin in prostate cancer patients undergoing salvage radiotherapy plus 2-year buserelin acetate for rising PSA after surgery
    Sarat Chander
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 62:719-24. 2005
    ..To examine the effect of 2-year androgen suppression (AS) on the pattern and extent of hemoglobin (Hb) change...
  12. doi request reprint Determining the incidence of pain flare following palliative radiotherapy for symptomatic bone metastases: results from three canadian cancer centers
    Amanda Hird
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 75:193-7. 2009
    ..To determine the incidence of pain flare following radiotherapy (RT) for painful bone metastases...
  13. doi request reprint Pain flare is a common adverse event in steroid-naïve patients after spine stereotactic body radiation therapy: a prospective clinical trial
    Andrew Chiang
    Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 86:638-42. 2013
    ..To determine the incidence of pain flare after spine stereotactic body radiation therapy (SBRT) in steroid-naïve patients and identify predictive factors...
  14. ncbi request reprint Variants of the hK2 protein gene (KLK2) are associated with serum hK2 levels and predict the presence of prostate cancer at biopsy
    Robert K Nam
    Division of Urology Department of Pathology, Sunnybrook Health Sciences Centre, University Health Network, Mount Sinai Hospital, University of Toronto, Ontario, Canada
    Clin Cancer Res 12:6452-8. 2006
    ..We examined five variants of the KLK2 gene to further define its relevance to prostate cancer susceptibility and hK2 levels...
  15. ncbi request reprint Accuracy of survival prediction by palliative radiation oncologists
    Edward Chow
    Division of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Int J Radiat Oncol Biol Phys 61:870-3. 2005
    ..To examine the accuracy of survival prediction by palliative radiation oncologists...
  16. doi request reprint Clinical results of long-term follow-up of a large, active surveillance cohort with localized prostate cancer
    Laurence Klotz
    Department of Urology, Sunnybrook Health Sciences Centre, 2075 Bayview Ave, MG408, Toronto, Ontario M4N 3M5 Canada
    J Clin Oncol 28:126-31. 2010
    ..Other-cause mortality accounted for almost all of the deaths. Additional studies are warranted to improve the identification of patients who harbor more aggressive disease despite favorable clinical parameters at diagnosis...
  17. doi request reprint Association between germline HOXB13 G84E mutation and risk of prostate cancer
    Mohammad R Akbari
    Women s College Research Institute, Women s College Hospital, Toronto, ON, Canada
    J Natl Cancer Inst 104:1260-2. 2012
    ..7%] vs 2 of 1757 [0.1%], P = .01) and was associated with an increased risk of prostate cancer (unadjusted odds ratio = 5.8, 95% confidence interval = 1.3 to 26.5, P = .01)...
  18. ncbi request reprint Patient costs associated with external beam radiotherapy treatment for localized prostate cancer: the benefits of hypofractionated over conventionally fractionated radiotherapy
    Perakaa Sethukavalan
    Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Can J Urol 19:6165-9. 2012
    ..To estimate the out-of-pocket costs for patients undergoing external beam radiotherapy (EBRT) for prostate cancer and calculate the patient-related savings of being treated with a 5-fraction versus a standard 39-fraction approach...
  19. ncbi request reprint Modeling prostate specific antigen kinetics in patients on active surveillance
    Liying Zhang
    Division of Clinical Trials and Epidemiology, and Department of Radiation Oncology, and Division of Urology, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Urol 176:1392-7; discussion 1397-8. 2006
    ..Prostate specific antigen doubling time was used to stratify patients into groups at low and high risk for progression. The prostate specific antigen kinetics in these 2 groups were modeled...
  20. doi request reprint Dramatic increase in prostate cancer cases by 2021
    Harvey Quon
    Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Ont, Canada
    BJU Int 108:1734-8. 2011
    ..This study also incorporates changes in screening prevalence, sensitivity screening maneuvers and lowering threshold for biopsies...
  21. ncbi request reprint Communication with referring physicians in a palliative radiotherapy clinic
    Elizabeth A Barnes
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, M4 N 3M5, Canada
    Support Care Cancer 12:669-73. 2004
    ..The purpose of this study was to assess how useful referring physicians perceive this interim report and whether this report needs to be modified to meet their information needs...
  22. ncbi request reprint How are hemoglobin levels affected by androgen deprivation in non-metastatic prostate cancer patients?
    Richard Choo
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    Can J Urol 12:2547-52. 2005
    ..To examine the change of hemoglobin in relation to testosterone level in non-metastatic prostate cancer patients receiving 2-year androgen suppression...
  23. ncbi request reprint A comparison of anatomy-based inverse planning with simulated annealing and graphical optimization for high-dose-rate prostate brachytherapy
    Gerard C Morton
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    Brachytherapy 7:12-6. 2008
    ..The purpose of this study is to compare dose distributions achieved using IPSA to those obtained with a graphical optimization (GrO) algorithm for prostate HDR brachytherapy...
  24. ncbi request reprint Computed tomography (CT) evaluation of breast cancer patients with osteolytic bone metastases undergoing palliative radiotherapy--a feasibility study
    Edward Chow
    Rapid Response Radiotherapy Program and Bone Metastases Site Group, Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
    Radiother Oncol 70:291-4. 2004
    ..The median % density change following single 8Gy, 20Gy/5#, 30Gy/10# were: 128 (range 98-255), 141 (79-342), and 145 (65-235), respectively. It is feasible to evaluate remineralization of osteolytic lesions with palliative radiotherapy...
  25. ncbi request reprint Comparative study of dosimetry between high-dose-rate and permanent prostate implant brachytherapies in patients with prostate adenocarcinoma
    Yongjin Wang
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, Toronto, Canada
    Brachytherapy 5:251-5. 2006
    ..To compare the dose coverage, conformity, and homogeneity between high-dose-rate (HDR) brachytherapy and permanent prostate implant (PPI) in the treatment of prostate adenocarcinoma...
  26. doi request reprint Fostering partnerships in survivorship care: report of the 2011 Canadian genitourinary cancers survivorship conference
    Jacqueline L Bender
    ELLICSR Health, Wellness and Cancer Survivorship Centre, Toronto General Hospital, University Health Network, Clinical Services Building, BCS021, 200 Elizabeth Street, Toronto, ON, M5G 2C4, Canada
    J Cancer Surviv 6:296-304. 2012
    ..A group of clinicians in collaboration with the Canadian Urologic Association held a forum for GU cancer survivors, advocacy groups, and health professionals to explore ways to collaboratively enhance survivorship care...
  27. ncbi request reprint Radiotherapeutic approaches to metastatic disease
    Edward Chow
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, 2075 Bayview Avenue, ON M4 N 3M5, Toronto, Canada
    World J Urol 21:229-42. 2003
    ..This article focuses on the management of bone pain and its complications (pathological fractures and spinal cord compression) with radiation treatment...
  28. ncbi request reprint Nomogram prediction for prostate cancer and aggressive prostate cancer at time of biopsy: utilizing all risk factors and tumor markers for prostate cancer
    Robert K Nam
    Division of Urology, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Can J Urol 13:2-10. 2006
    ..There is a large amount of confusion in interpreting prostate specific antigen (PSA) values for prostate cancer. More precise risk assessments for prostate cancer detection are needed for men faced with an abnormal PSA...
  29. ncbi request reprint A population-based study of malignant spinal cord compression in Ontario
    D A Loblaw
    Division of Cancer Care and Epidemiology, Queen s Cancer Research Institute, Queen s University, Kingston Regional Cancer Centre and Kingston General Hospital, Kingston, Ontario, Canada
    Clin Oncol (R Coll Radiol) 15:211-7. 2003
    ..Population-based cohort study...
  30. ncbi request reprint Urolith masquerading as severe acute radiation toxicity: case report
    Daniel Toguri
    Clinical Clerk, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada
    Can J Urol 17:5040-3. 2010
    ..We describe an unusual case of a patient experiencing severe, culture negative urinary symptoms early in a course of salvage radiotherapy...
  31. ncbi request reprint Multidisciplinary radiation oncology palliative care rounds as a continuing educational activity implementing the rapid response radiotherapy program at the toronto sunnybrook regional cancer centre
    Ewa Szumacher
    Department of Radiation Oncology, University of Toronto, Ontario, Canada
    J Cancer Educ 18:86-90. 2003
    ....
  32. ncbi request reprint A phase I/II study to evaluate the toxicity and efficacy of accelerated fractionation radiotherapy for the palliation of dysphagia from carcinoma of the oesophagus
    Z Kassam
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Canada
    Clin Oncol (R Coll Radiol) 20:53-60. 2008
    ..A phase I/II accelerated fractionation study was conducted to evaluate the efficacy and toxicity of this approach...