Harriette J Kahn

Summary

Affiliation: Sunnybrook and Women's College Health Sciences Centre
Country: Canada

Publications

  1. ncbi request reprint Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi's sarcoma and a subset of angiosarcomas
    Harriette J Kahn
    Department of Pathology, Women s College Campus, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Mod Pathol 15:434-40. 2002
  2. ncbi request reprint A new monoclonal antibody, D2-40, for detection of lymphatic invasion in primary tumors
    Harriette J Kahn
    Department of Pathology, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Lab Invest 82:1255-7. 2002
  3. ncbi request reprint Analysis of the HER2/neu gene amplification in microdissected breast cancer tumour samples
    Rishie M Seth
    Department of Anatomic Pathology, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Anticancer Res 26:927-31. 2006
  4. ncbi request reprint Biological significance of occult micrometastases in histologically negative axillary lymph nodes in breast cancer patients using the recent American Joint Committee on Cancer breast cancer staging system
    Harriette J Kahn
    Department of Pathology, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    Breast J 12:294-301. 2006
  5. ncbi request reprint Breast cancer metastasis in a human bone NOD/SCID mouse model
    Wenyi Yang
    Division of Molecular and Cellular Biology, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada
    Cancer Biol Ther 6:1289-94. 2007
  6. ncbi request reprint RT-PCR amplification of CK19 mRNA in the blood of breast cancer patients: correlation with established prognostic parameters
    H J Kahn
    Department of Pathology, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Breast Cancer Res Treat 60:143-51. 2000
  7. ncbi request reprint Ascertaining prognosis for breast cancer in node-negative patients with innovative survival analysis
    Judith Anne W Chapman
    Department of Public Health Sciences, Faculty of Medicine, University of Toronto, and Department of Laboratory Medicine and Pathology, St Michael s Hospital, Toronto, Ontario, Canada
    Breast J 12:37-47. 2006
  8. doi request reprint Lymphatic invasion identified by monoclonal antibody D2-40, younger age, and ulceration: predictors of sentinel lymph node involvement in primary cutaneous melanoma
    Firouzeh Niakosari
    Department of Pathology, Sunnybrook Health Sciences Centre, University Health Network, Room E4 33, 2075 Bayview Ave, Toronto, ON M4N 3M5, Canada
    Arch Dermatol 144:462-7. 2008
  9. ncbi request reprint Prognostic significance of circulating tumour cells enumerated after filtration enrichment in early and metastatic breast cancer patients
    Nan Soon Wong
    Department of Medical Oncology, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Breast Cancer Res Treat 99:63-9. 2006
  10. ncbi request reprint Significance of lymph vessel invasion identified by the endothelial lymphatic marker D2-40 in node negative breast cancer
    Angel Arnaout-Alkarain
    Department of Surgery, Sunnybrook Health Sciences Centre and Women s College Hospital, University of Toronto, Toronto, ON, Canada
    Mod Pathol 20:183-91. 2007

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi's sarcoma and a subset of angiosarcomas
    Harriette J Kahn
    Department of Pathology, Women s College Campus, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Mod Pathol 15:434-40. 2002
    ..We conclude that D2-40 is a new selective marker of lymphatic endothelium in normal tissues and vascular lesions and is valuable for studying benign and malignant vascular disorders in routinely processed tissue specimens...
  2. ncbi request reprint A new monoclonal antibody, D2-40, for detection of lymphatic invasion in primary tumors
    Harriette J Kahn
    Department of Pathology, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Lab Invest 82:1255-7. 2002
  3. ncbi request reprint Analysis of the HER2/neu gene amplification in microdissected breast cancer tumour samples
    Rishie M Seth
    Department of Anatomic Pathology, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Anticancer Res 26:927-31. 2006
    ..Our results indicated that LCM is a powerful technique for isolating pure populations of cells from paraffin-embedded tissue sections and that these cells can be used to study genomic alterations at the DNA level...
  4. ncbi request reprint Biological significance of occult micrometastases in histologically negative axillary lymph nodes in breast cancer patients using the recent American Joint Committee on Cancer breast cancer staging system
    Harriette J Kahn
    Department of Pathology, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    Breast J 12:294-301. 2006
    ..This information is important with regard to the practice of sentinel node biopsy and subsequent axillary node dissection and to the decision to administer adjuvant therapy based on detection of micrometastases in lymph nodes...
  5. ncbi request reprint Breast cancer metastasis in a human bone NOD/SCID mouse model
    Wenyi Yang
    Division of Molecular and Cellular Biology, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada
    Cancer Biol Ther 6:1289-94. 2007
    ..With this model, we can distinguish between primary invasive breast tumors with and without bone metastatic potential...
  6. ncbi request reprint RT-PCR amplification of CK19 mRNA in the blood of breast cancer patients: correlation with established prognostic parameters
    H J Kahn
    Department of Pathology, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Breast Cancer Res Treat 60:143-51. 2000
    ..In a small number of patients with distant metastases, increased intensity of the CK19 RT-PCR signal was associated with a reduced survival...
  7. ncbi request reprint Ascertaining prognosis for breast cancer in node-negative patients with innovative survival analysis
    Judith Anne W Chapman
    Department of Public Health Sciences, Faculty of Medicine, University of Toronto, and Department of Laboratory Medicine and Pathology, St Michael s Hospital, Toronto, Ontario, Canada
    Breast J 12:37-47. 2006
    ..Estimated prognoses may differ substantially by survival analysis model type, by amounts that might affect patient management, and we think that the log-normal model has a major advantage over the Cox model for survival analysis...
  8. doi request reprint Lymphatic invasion identified by monoclonal antibody D2-40, younger age, and ulceration: predictors of sentinel lymph node involvement in primary cutaneous melanoma
    Firouzeh Niakosari
    Department of Pathology, Sunnybrook Health Sciences Centre, University Health Network, Room E4 33, 2075 Bayview Ave, Toronto, ON M4N 3M5, Canada
    Arch Dermatol 144:462-7. 2008
    ....
  9. ncbi request reprint Prognostic significance of circulating tumour cells enumerated after filtration enrichment in early and metastatic breast cancer patients
    Nan Soon Wong
    Department of Medical Oncology, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Breast Cancer Res Treat 99:63-9. 2006
    ..We previously found a higher incidence of circulating tumour cells (CTCs) in women with metastatic breast cancer compared to early disease. In this study, we present follow-up data to explore the prognostic significance of these findings...
  10. ncbi request reprint Significance of lymph vessel invasion identified by the endothelial lymphatic marker D2-40 in node negative breast cancer
    Angel Arnaout-Alkarain
    Department of Surgery, Sunnybrook Health Sciences Centre and Women s College Hospital, University of Toronto, Toronto, ON, Canada
    Mod Pathol 20:183-91. 2007
    ..02) were associated with overall shorter survival in univariate analysis. These data indicate that D2-40 identifies lymphatic invasion in breast tumors and is a significant predictor of outcome in breast cancer...
  11. ncbi request reprint A novel RING-type ubiquitin ligase breast cancer-associated gene 2 correlates with outcome in invasive breast cancer
    Angelika M Burger
    Laboratories of Molecular Pathology, Department of Anatomic Pathology, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Cancer Res 65:10401-12. 2005
    ..Its association with clinical measures and its effects on cell growth indicate that BCA2 may be important for the ubiquitin modification of proteins crucial to breast carcinogenesis and growth...
  12. ncbi request reprint Imaging of HER2/neu-positive BT-474 human breast cancer xenografts in athymic mice using (111)In-trastuzumab (Herceptin) Fab fragments
    Ying Tang
    Division of Nuclear Medicine, University Health Network, Toronto, Ontario, M5G 2C4, Canada
    Nucl Med Biol 32:51-8. 2005
    ..7+/-0.7% ID/g and 7.0+/-0.9 for (111)In-HuM195 anti-CD33 Fab (significantly different, P<.001). Small (3-5 mm in diameter) BT-474 tumors were imaged with (111)In-trastuzumab Fab as early as 24 h postinjection...
  13. ncbi request reprint Etiologic factors associated with p53 immunostaining in cutaneousmalignant melanoma
    Mark P Purdue
    Division of Preventive Oncology, Cancer Care Ontario, Toronto, Ontario, Canada
    Int J Cancer 117:486-93. 2005
    ....
  14. ncbi request reprint Enumeration of circulating tumor cells in the blood of breast cancer patients after filtration enrichment: correlation with disease stage
    Harriette J Kahn
    Department of Pathology, Sunnybrook and Women s College Health Sciences Centre SWCHSC, Toronto, Ontario, Canada
    Breast Cancer Res Treat 86:237-47. 2004
    ..Our results support the concept that CTC can be detected and enumerated in peripheral blood and that this minimally invasive assay merits further evaluation as a potential prognostic indicator and marker of disease progression...
  15. ncbi request reprint Intratumoral heterogeneity of HER2/neu in breast cancer--a rare event
    Wedad Hanna
    Department of Pathology, Sunnybrook Health Sciences Center, Toronto, Ontario, Canada
    Breast J 13:122-9. 2007
    ....
  16. ncbi request reprint Detection of lymphatic invasion in primary melanoma with monoclonal antibody D2-40: a new selective immunohistochemical marker of lymphatic endothelium
    Firouzeh Niakosari
    Departments of Pathology and Dermatology, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    Arch Dermatol 141:440-4. 2005
    ....
  17. ncbi request reprint Prognostic factors affecting the natural history of node-negative breast cancer
    Maureen E Trudeau
    Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    Breast Cancer Res Treat 89:35-45. 2005
    ..We undertook a natural history investigation of a broad selection of prognostic factors in a cohort of women with node-negative breast cancer...
  18. doi request reprint D2-40 is expressed on the luminal surface of pulmonary airspaces in normal developing and adult lung but is lost in conditions associated with intra-alveolar infiltrates
    Christopher G Sherman
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Room E432, Toronto, ON, M4N 3M5, Canada
    Pediatr Dev Pathol 15:259-64. 2012
    ..These results suggest that D2-40 may have a cell membrane protective function...
  19. doi request reprint Breast metastasis by medullary thyroid carcinoma detected by FDG positron emission tomography
    Sharon Nofech-Mozes
    Department of Anatomical Pathology, Sunnybrook Health Sciences Center, Toronto, ON, Canada M4N 3M5
    Ann Diagn Pathol 12:67-71. 2008
    ....