W M Hanna

Summary

Affiliation: Sunnybrook and Women's College Health Sciences Centre
Country: Canada

Publications

  1. ncbi Aggressive giant fibroepithelial lesion with unusual vascular stroma--a case report
    Wedad Hanna
    Department of Anatomical Pathology, Sunnybrook and Women s College Health Science Center, University of Toronto, Ontario, Canada
    Mod Pathol 16:823-7. 2003
  2. pmc Chromogenic in situ hybridisation for the assessment of HER2 status in breast cancer: an international validation ring study
    Marc van de Vijver
    Netherlands Cancer Institute, Amsterdam, The Netherlands
    Breast Cancer Res 9:R68. 2007
  3. ncbi Defining a test for HER-2/neu evaluation in breast cancer in the diagnostic setting
    W M Hanna
    Sunnybrook and Women s College Health Sciences CentreDepartments of Pathology, University of Toronto, Toronto, Ontario, Canada
    Mod Pathol 14:677-85. 2001
  4. ncbi Testing for HER2 status
    W Hanna
    Sunnybrook and Women s College Health Sciences Centre, Toronto, Ont, Canada
    Oncology 61:22-30. 2001
  5. ncbi Breast adipose tissue concentrations of polychlorinated biphenyls and other organochlorines and breast cancer risk
    K J Aronson
    Department of Community Health and Epidemiology, Queen s University, Kingston, Ontario, Canada
    Cancer Epidemiol Biomarkers Prev 9:55-63. 2000
  6. ncbi Factors affecting distant disease-free survival for primary invasive breast cancer: use of a log-normal survival model
    D R McCready
    Department of Surgical Oncology, Princess Margaret Hospital, Toronto, Ontario, Canada
    Ann Surg Oncol 7:416-26. 2000
  7. ncbi Granuloma annulare: an elastic tissue disease? Case report and literature review
    W M Hanna
    Women s College Hospital, The University of Toronto, Ontario, Canada
    Ultrastruct Pathol 23:33-8. 1999
  8. ncbi Organochlorines and breast cancer risk by receptor status, tumor size, and grade (Canada)
    C G Woolcott
    Department of Community Health and Epidemiology, Queen's University, Kingston, Ontario, Canada
    Cancer Causes Control 12:395-404. 2001
  9. doi Cancer care Ontario guideline recommendations for hormone receptor testing in breast cancer
    S Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    Clin Oncol (R Coll Radiol) 24:684-96. 2012
  10. ncbi "Aberrant elastic" in elastofibroma: an immunohistochemical and ultrastructural study
    H J Kahn
    Department of Pathology, Women s College Hospital, Toronto, Ontario, Canada
    Ultrastruct Pathol 19:45-50. 1995

Collaborators

Detail Information

Publications22

  1. ncbi Aggressive giant fibroepithelial lesion with unusual vascular stroma--a case report
    Wedad Hanna
    Department of Anatomical Pathology, Sunnybrook and Women s College Health Science Center, University of Toronto, Ontario, Canada
    Mod Pathol 16:823-7. 2003
    ..The extensive vascular stroma noted in the primary tumor may have played a role in the malignant transformation of the epithelial and stromal components in this tumor...
  2. pmc Chromogenic in situ hybridisation for the assessment of HER2 status in breast cancer: an international validation ring study
    Marc van de Vijver
    Netherlands Cancer Institute, Amsterdam, The Netherlands
    Breast Cancer Res 9:R68. 2007
    ....
  3. ncbi Defining a test for HER-2/neu evaluation in breast cancer in the diagnostic setting
    W M Hanna
    Sunnybrook and Women s College Health Sciences CentreDepartments of Pathology, University of Toronto, Toronto, Ontario, Canada
    Mod Pathol 14:677-85. 2001
    ..These results show that there is excellent concordance between IH and PCR. However, immunohistochemistry is easier to perform and cheaper than PCR and could be used in routine assessment of HER-2/neu in breast cancer patients...
  4. ncbi Testing for HER2 status
    W Hanna
    Sunnybrook and Women s College Health Sciences Centre, Toronto, Ont, Canada
    Oncology 61:22-30. 2001
    ..Confirmatory HER2 testing using either FISH or quantitative PCR is recommended for indeterminate cases. Additional studies are required to calibrate HER2 testing results to clinical outcome...
  5. ncbi Breast adipose tissue concentrations of polychlorinated biphenyls and other organochlorines and breast cancer risk
    K J Aronson
    Department of Community Health and Epidemiology, Queen s University, Kingston, Ontario, Canada
    Cancer Epidemiol Biomarkers Prev 9:55-63. 2000
    ..Clear associations with breast cancer risk were demonstrated in this study for some PCBs measured in breast adipose tissue...
  6. ncbi Factors affecting distant disease-free survival for primary invasive breast cancer: use of a log-normal survival model
    D R McCready
    Department of Surgical Oncology, Princess Margaret Hospital, Toronto, Ontario, Canada
    Ann Surg Oncol 7:416-26. 2000
    ..Invasive breast cancer is a frequently diagnosed disease that now comes with an ever expanding array of therapeutic management options. We assessed the effects of 20 prognostic factors in a multivariate context...
  7. ncbi Granuloma annulare: an elastic tissue disease? Case report and literature review
    W M Hanna
    Women s College Hospital, The University of Toronto, Ontario, Canada
    Ultrastruct Pathol 23:33-8. 1999
    ..These findings show that the main alteration in GA is elastic fiber degeneration and strongly suggest that the primary target leading to the development of this disorder is injury to the elastic tissue...
  8. ncbi Organochlorines and breast cancer risk by receptor status, tumor size, and grade (Canada)
    C G Woolcott
    Department of Community Health and Epidemiology, Queen's University, Kingston, Ontario, Canada
    Cancer Causes Control 12:395-404. 2001
    ..CONCLUSIONS: The association between organochlorines and breast cancer risk did not significantly differ by subtype, but many PCBs were more strongly associated with tumors of poor prognosis...
  9. doi Cancer care Ontario guideline recommendations for hormone receptor testing in breast cancer
    S Nofech-Mozes
    Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    Clin Oncol (R Coll Radiol) 24:684-96. 2012
    ..A formal external review was conducted to validate the relevance of these recommendations. It is anticipated that widespread adoption of these guidelines will further improve the accuracy of hormone receptor testing in Canada...
  10. ncbi "Aberrant elastic" in elastofibroma: an immunohistochemical and ultrastructural study
    H J Kahn
    Department of Pathology, Women s College Hospital, Toronto, Ontario, Canada
    Ultrastruct Pathol 19:45-50. 1995
    ..Our study suggests that abnormal elastogenesis with subsequent degeneration plays a role in the production of the abnormal elastic fibers in elastofibroma...
  11. ncbi In situ duct carcinoma of the breast: clinical and histopathologic factors and association with recurrent carcinoma
    N A Miller
    Department of Pathology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Breast J 7:292-302. 2001
    ..Longer follow-up will allow further evaluation of the prognostic relevance of the factors assessed...
  12. ncbi Hormone receptor profile of apocrine lesions of the breast
    Michelle Sapp
    Breast J 9:335-6. 2003
  13. ncbi Significance of multifocality in ductal carcinoma in situ: outcomes of women treated with breast-conserving therapy
    Eileen Rakovitch
    Toronto Sunnybrook Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada
    J Clin Oncol 25:5591-6. 2007
    ..The objective of this study is to evaluate the significance of multifocality and the outcomes of women with multifocal DCIS treated with breast-conserving therapy...
  14. ncbi Intratumoral heterogeneity of HER2/neu in breast cancer--a rare event
    Wedad Hanna
    Department of Pathology, Sunnybrook Health Sciences Center, Toronto, Ontario, Canada
    Breast J 13:122-9. 2007
    ....
  15. pmc p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
    Isabel Chu
    Braman Family Breast Cancer Institute of the University of Miami Sylvester Comprehensive Cancer Center and Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Cell 128:281-94. 2007
    ..Importantly, we report that in tamoxifen-resistant breast cancer cell lines, Src inhibition can increase p27 levels and restore tamoxifen sensitivity. These data provide a new rationale for Src inhibitors in cancer therapy...
  16. ncbi The management of ductal carcinoma in situ of the breast: a screened population-based analysis
    Eileen Rakovitch
    Department of Radiation Oncology and Health Policy and Evaluation, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ont, Canada
    Breast Cancer Res Treat 101:335-47. 2007
    ..We report a patterns of care study of women with DCIS to better understand the gap between evidence-based knowledge and the management of DCIS...
  17. ncbi Prognostic and predictive molecular markers in DCIS: a review
    Sharon Nofech-Mozes
    Department of Pathology, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    Adv Anat Pathol 12:256-64. 2005
    ..However, controversies exist regarding the value of these prognostic factors, their interrelationship, and their advantages over morphologic evaluation...
  18. pmc The gene associated with trichorhinophalangeal syndrome in humans is overexpressed in breast cancer
    Laszlo Radvanyi
    Sanofi Pasteur, Toronto, Ontario, Canada M2R 3T4
    Proc Natl Acad Sci U S A 102:11005-10. 2005
    ..1 transgenic mouse. Human T cell lines from HLA-A*0201+ female donors exhibiting TRPS-1-specific cytotoxic T lymphocyte activity could also be generated...
  19. ncbi Is expert breast pathology assessment necessary for the management of ductal carcinoma in situ ?
    Eileen Rakovitch
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, Sunnybrook and Women s College Health Sciences Centre, 2075 Bayview Avenue, Ontario, Canada
    Breast Cancer Res Treat 87:265-72. 2004
    ..The objective of this study was to evaluate the completeness and accuracy of pathologic reporting of DCIS over the past decade and to determine the current impact of expert breast pathology assessment on the management of DCIS...
  20. ncbi The role of HER-2/neu oncogene and vimentin filaments in the production of the Paget's phenotype
    Wedad Hanna
    Department of Pathology, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    Breast J 9:485-90. 2003
    ....
  21. ncbi Current perspectives on HER2 testing: a review of national testing guidelines
    Michael Bilous
    Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales, Australia
    Mod Pathol 16:173-82. 2003
    ..The key point underlined by this review is that whatever method is used to test for HER2 status, the technology must be validated first, and there must be regular internal and external quality control and quality assurance procedures...
  22. ncbi Disruption of the expected positive correlation between breast tumor size and lymph node status in BRCA1-related breast carcinoma
    William D Foulkes
    Department of Oncology, McGill University, Montreal, Quebec, Canada
    Cancer 98:1569-77. 2003
    ..Therefore, the authors questioned whether the known positive correlation between tumor size and lymph node status also was present in women with BRCA1-related breast carcinomas...