Research Topics
| Benjamin I GoldsteinSummaryAffiliation: Sunnybrook Health Sciences Centre Country: Canada Publications
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Detail Information
Publications
Pharmacologic treatment of bipolar disorder in children and adolescentsBenjamin I Goldstein
Departments of Psychiatry and Pharmacology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Child Adolesc Psychiatr Clin N Am 21:911-39. 2012..A clinical vignette describing a teen with bipolar disorder is presented and bipolar medications, dosing, efficacy, side effects, contraindications, and succinct comments on each medication are summarized...- Recent progress in understanding pediatric bipolar disorderBenjamin I Goldstein
Department of Psychiatry, Sunnybrook Health Sciences Centre, 2075 Bayview Ave, FG53, Toronto, ON M4N 3M5, Canada
Arch Pediatr Adolesc Med 166:362-71. 2012..Preliminary findings regarding biomarkers offer hope that, in the future, these biomarkers may inform diagnostic and treatment decisions... 
The burden of obesity among adults with bipolar disorder in the United StatesBenjamin I Goldstein
Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Bipolar Disord 13:387-95. 2011..We therefore examined this topic in a representative epidemiologic sample...- Preliminary findings regarding proinflammatory markers and brain-derived neurotrophic factor among adolescents with bipolar spectrum disordersBenjamin I Goldstein
Department of Psychiatry, Sunnybrook Health Sciences Centre, Faculty of Medicine, University of Toronto, Toronto, Canada
J Child Adolesc Psychopharmacol 21:479-84. 2011..Hypomanic/manic symptoms were positively associated with hsCRP. BDNF levels were negatively associated with interleukin-6. Forty percent had cardiovascular high-risk hsCRP levels. Larger longitudinal studies are warranted... - Cardiovascular disease and hypertension among adults with bipolar I disorder in the United StatesBenjamin I Goldstein
Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Bipolar Disord 11:657-62. 2009..We therefore examined this topic in a representative epidemiologic sample... - Comorbid substance use disorders among youth with bipolar disorder: opportunities for early identification and preventionBenjamin I Goldstein
Department of Psychiatry, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, FG53, Toronto, Ontario, Canada
J Clin Psychiatry 71:348-58. 2010..This article aims to integrate the extant literature on this topic and to suggest strategies for delaying or preventing SUD among youth with bipolar disorder... - Preliminary findings regarding overweight and obesity in pediatric bipolar disorderBenjamin I Goldstein
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
J Clin Psychiatry 69:1953-9. 2008..Overweight/obesity is highly prevalent among adults with bipolar disorder and has been associated with illness severity. Little is known regarding overweight/obesity among youth with bipolar disorder... - Clinical, demographic, and familial correlates of bipolar spectrum disorders among offspring of parents with bipolar disorderBenjamin I Goldstein
Faculty of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON M4N 3M5, Canada
J Am Acad Child Adolesc Psychiatry 49:388-96. 2010..The identification of risk factors for BP among offspring could improve preventive and treatment strategies. We examined this topic in the Pittsburgh Bipolar Offspring Study (BIOS)... - Factors associated with the persistence and onset of new anxiety disorders in youth with bipolar spectrum disordersRegina Sala
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
J Clin Psychiatry 73:87-94. 2012..Anxiety disorders are among the most common comorbid conditions in youth with bipolar disorder, but, to our knowledge, no studies examined the course of anxiety disorders in youth and adults with bipolar disorder... - Significance of cigarette smoking among youths with bipolar disorderBenjamin I Goldstein
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Am J Addict 17:364-71. 2008..Daily heavy smokers had greater prevalence of SUD and suicide attempts, and worse depression versus daily light smokers. Smoking among youths with BP is independently associated with suicide attempts and SUD... 
The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid metabolic disordersRoger S McIntyre
Mood Disorders Psychopharmacology Unit, University Health Network, Departments of Psychiatry and Pharmacology, University of Toronto, Toronto, Ontario, Canada
Ann Clin Psychiatry 24:69-81. 2012..Our group conducted a comprehensive literature review to provide evidence-based recommendations for treating metabolic comorbidity in individuals with major depressive disorder (MDD) and bipolar disorder (BD)...- Negative life events in children and adolescents with bipolar disorderSoledad Romero
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pennsylvania, USA
J Clin Psychiatry 70:1452-60. 2009.... - Comorbid anxiety in children and adolescents with bipolar spectrum disorders: prevalence and clinical correlatesRegina Sala
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
J Clin Psychiatry 71:1344-50. 2010..Anxiety disorders are among the most common comorbid conditions in youth with bipolar disorder. We aimed to examine the prevalence and correlates of comorbid anxiety disorders among youth with bipolar disorder... - Predictors of prospectively examined suicide attempts among youth with bipolar disorderTina R Goldstein
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pennsylvania 15213, USA
Arch Gen Psychiatry 69:1113-22. 2012..Individuals with early onset of bipolar disorder are at high risk for suicide. Yet, no study to date has examined factors associated with prospective risk for suicide attempts among youth with bipolar disorder... - Psychosocial functioning among bipolar youthTina R Goldstein
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
J Affect Disord 114:174-83. 2009..However, little is known about the association between psychosocial functioning and episodes of illness, demographic, and clinical variables in this population... - Family environment and suicidal ideation among bipolar youthTina R Goldstein
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Arch Suicide Res 13:378-88. 2009..Clinicians treating bipolar youth should consider family stress when conducting suicide risk assessment. Treatment goals may include enhancing family communication and addressing issues of loss... - The CANMAT task force recommendations for the management of patients with mood disorders and comorbid anxiety disordersAyal Schaffer
Mood and Anxiety Disorders Program, Sunnybrook Health Sciences Centre, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
Ann Clin Psychiatry 24:6-22. 2012..This article is part of a set of Canadian Network for Mood and Anxiety Treatments (CANMAT) Comorbidity Task Force papers... - Course of subthreshold bipolar disorder in youth: diagnostic progression from bipolar disorder not otherwise specifiedDavid A Axelson
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Am Acad Child Adolesc Psychiatry 50:1001-16.e3. 2011.... - Prevalence and correlates of bipolar I disorder among adults with primary youth-onset anxiety disordersBenjamin I Goldstein
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, United States
J Affect Disord 103:187-95. 2007.... - Risk for suicidal ideation among the offspring of bipolar parents: results from the Bipolar Offspring Study (BIOS)Tina R Goldstein
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara St, Pittsburgh, PA 15213, USA
Arch Suicide Res 15:207-22. 2011..Offspring of parents with bipolar disorder are at elevated risk for suicidal ideation as compared with offspring of controls. Suicide risk assessment in this population should attend to specific risk factors identified... - Factors associated with temporal priority in comorbid bipolar I disorder and alcohol use disorders: Results from the national epidemiologic survey on alcohol and related conditionsBenjamin I Goldstein
Mood Disorders Program, Department of Psychiatry, Sunnybrook and Women s Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
J Clin Psychiatry 67:643-9. 2006..To compare illness characteristics, comorbidities, treatment utilization, and family history among individuals with comorbid bipolar I disorder and alcohol use disorders (AUD) based on temporal priority of onset... - Further evidence for a developmental subtype of bipolar disorder defined by age at onset: results from the national epidemiologic survey on alcohol and related conditionsBenjamin I Goldstein
Department of Psychiatry, Sunnybrook and Women's Health Sciences Centre, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
Am J Psychiatry 163:1633-6. 2006..CONCLUSIONS: Findings corroborate clinical studies: illness characteristics among adults with childhood-onset bipolar disorder are similar to those described in children with bipolar disorder... - Inflammation and the phenomenology, pathophysiology, comorbidity, and treatment of bipolar disorder: a systematic review of the literatureBenjamin I Goldstein
Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 16213, USA
J Clin Psychiatry 70:1078-90. 2009.... - Course of comorbid anxiety disorders among adults with bipolar disorder in the U.S. populationRegina Sala
Department of Psychiatry, New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 69, New York, NY 10032, USA
J Psychiatr Res 46:865-72. 2012..To examine the prevalence and correlates of comorbid anxiety disorders among individuals with bipolar disorders (BP) and their association with prospectively ascertained comorbidities, treatment, and psychosocial functioning... - The specific burden of comorbid anxiety disorders and of substance use disorders in bipolar I disorderBenjamin I Goldstein
Mood Disorders Program, Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Bipolar Disord 10:67-78. 2008..Moreover, the independent contribution of these comorbidities to the burden of bipolar disorder (BD) is unclear... - Substance use disorders among adolescents with bipolar spectrum disordersBenjamin I Goldstein
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Bipolar Disord 10:469-78. 2008..We set out to examine the prevalence and correlates of substance use disorders (SUD) in a large sample of adolescents with bipolar disorder (BP)... - Factors associated with pain interference in an epidemiologic sample of adults with bipolar I disorderBenjamin I Goldstein
Advanced Center for Intervention and Services Research for Late Life Mood Disorders, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States
J Affect Disord 117:151-6. 2009..Epidemiologic studies have found that major depressive disorder (MDD) and anxiety disorders are associated with pain. However, little is known regarding the prevalence and correlates of pain in bipolar I disorder (BD)... - Childhood onset major depressive disorder: course of illness and psychiatric comorbidity in a community sampleDaphne J Korczak
Department of Psychiatry, The Hospital for Sick Children and the University of Toronto, Toronto, Ontario, Canada
J Pediatr 155:118-23. 2009..To examine the effect of childhood-onset major depressive disorder (MDD) on course of illness and psychiatric comorbidity, as compared with adolescent- and adult-onset MDD, in a large nonclinical sample... - Comorbidity in bipolar disorder among the elderly: results from an epidemiological community sampleBenjamin I Goldstein
Department of Psychiatry, Sunnybrook and Women s Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada M4N 3M5
Am J Psychiatry 163:319-21. 2006..This study sought to determine psychiatric comorbidity among elderly individuals with bipolar disorder... - Schedule for affective disorders and schizophrenia for school-age children (K-SADS-PL) for the assessment of preschool children--a preliminary psychometric studyBoris Birmaher
University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Psychiatr Res 43:680-6. 2009.... - Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013Lakshmi N Yatham
Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada
Bipolar Disord 15:1-44. 2013..Asenapine alone or as adjunctive therapy have been added as third-line options... - Metabolic syndrome and major depressive disorder: co-occurrence and pathophysiologic overlapRoger S McIntyre
Mood Disorders Psychopharmacology Unit, University Health Network, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada
Curr Diab Rep 9:51-9. 2009..This article discusses the rate of co-occurrence and the points of pathophysiologic commonality between the metabolic syndrome and major depressive disorder... - Is current alcohol consumption associated with increased lifetime prevalence of major depression and suicidality? Results from a pilot community surveyBenjamin I Goldstein
Department of Psychiatry, Sunnybrook and Women s Health Sciences Centre, University of Toronto, Toronto, ON, Canada M4N 3M5
Compr Psychiatry 47:330-3. 2006..Alcohol use disorders are associated with increased illness severity and suicidality in major depressive disorder (MDD). However, little is known about how alcohol use across the continuum relates to MDD... - A gender-focused perspective on health service utilization in comorbid bipolar I disorder and alcohol use disorders: results from the national epidemiologic survey on alcohol and related conditionsBenjamin I Goldstein
Mood Disorders Program, Department of Psychiatry, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
J Clin Psychiatry 67:925-32. 2006..This study compares health service utilization by individuals with comorbid lifetime bipolar I disorder and lifetime alcohol use disorders (AUD) to that of individuals with either diagnosis alone, using nationally representative data... - A brief motivational intervention for preventing medication-associated weight gain among youth with bipolar disorder: treatment development and case reportTina R Goldstein
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
J Child Adolesc Psychopharmacol 21:275-80. 2011.... - Panic disorder, cardiac diagnosis and emergency department utilization in an epidemiologic community sampleDaphne J Korczak
Department of Psychiatry, The University of Toronto, Toronto, Ontario, Canada M5S 1A1
Gen Hosp Psychiatry 29:335-9. 2007.... - The effect of tumor necrosis factor antagonists on mood and mental health-associated quality of life: novel hypothesis-driven treatments for bipolar depression?Joanna K Soczynska
Institute of Medical Sciences, University of Toronto, Canada
Neurotoxicology 30:497-521. 2009..e. adalimumab, etanercept, and infliximab) on depressive symptoms and mental health-associated quality of life measures... - Pharmacotherapy of alcoholism in patients with co-morbid psychiatric disordersBenjamin I Goldstein
Department of Psychiatry, Sunnybrook and Women's College Health Sciences Centre, University of Toronto, Toronto, Canada
Drugs 66:1229-37. 2006..Effectiveness, safety and tolerability are considered, and directions for future study are discussed... - The association between moderate alcohol use and illness severity in bipolar disorder: a preliminary reportBenjamin I Goldstein
Department of Psychiatry, University of Toronto, Sunnybrook and Women s College Health Sciences Center, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
J Clin Psychiatry 67:102-6. 2006..To examine the association of alcohol consumption with symptoms, illness course, and health care utilization among non-alcoholic patients with bipolar disorder...