Research Topics
| Robert A FowlerSummaryAffiliation: Sunnybrook Health Sciences Centre Country: Canada Publications
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Detail Information
Publications
Duration of antibiotic therapy for bacteremia: a systematic review and meta-analysisThomas C Havey
Department of Medicine, University of Toronto, 1 Kings College Circle, O, M5S 1A8, Canada
Crit Care 15:R267. 2011....- When should a diagnosis of influenza be considered in adults requiring intensive care unit admission? Results of population-based active surveillance in TorontoStefan P Kuster
Mount Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada
Crit Care 15:R182. 2011.... - Critical care resources in the Solomon Islands: a cross-sectional surveyMia Westcott
George Institute For Global Health, PO Box M201, Missenden Road Sydney, NSW 2050, Australia
BMC Int Health Hum Rights 12:1. 2012..abstract:.. - A Canadian Critical Care Trials Group project in collaboration with the international forum for acute care trialists - Collaborative H1N1 Adjuvant Treatment pilot trial (CHAT): study protocol and design of a randomized controlled trialKaren E A Burns
Interdepartmental Division of Critical Care Medicine and Departments of Pharmacy, University of Toronto, Toronto, Ontario, Canada
Trials 12:70. 2011.... - Oncoming tides in the Age(ing) of AquariusDavid W Frost
Department of Medicine and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto M4N 3M5, Canada
Crit Care 13:145. 2009.... - Venous thromboembolism and bleeding in critically ill patients with severe renal insufficiency receiving dalteparin thromboprophylaxis: prevalence, incidence and risk factorsDeborah Cook
Department of Medicine, 1200 Main Street, McMaster University, Hamilton, Canada
Crit Care 12:R32. 2008..The objective of the present study was to evaluate the prevalence, incidence and predictors of DVT and the incidence of bleeding in intensive care unit (ICU) patients with estimated creatinine clearance <30 ml/min... - Multi-drug resistant Acinetobacter infections in critically injured Canadian forces soldiersHomer C Tien
The Trauma Program, and Department of Surgery, Sunnybrook Health Sciences Centre, H186 2075 Bayview Avenue, Toronto, Canada, M4N 3M5
BMC Infect Dis 7:95. 2007..Military members, injured in Afghanistan or Iraq, have returned home with multi-drug resistant Acinetobacter baumannii infections. The source of these infections is unknown... 
Update in critical care 2007Robert A Fowler
Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada
Am J Respir Crit Care Med 177:808-19. 2008
Sex and critical illnessRobert A Fowler
Department of Medicine, Interdepartmental Division of Critical Care Medicine, University of Toronto, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Curr Opin Crit Care 15:442-9. 2009..The article reviews and speculates on potential mechanisms underlying sex-related differences in admission patterns, care delivery and outcome of critical illness...- Sex-and age-based differences in the delivery and outcomes of critical careRobert A Fowler
Interdepartmental Division of Critical Care Medicine and Department of Medicine, University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ont
CMAJ 177:1513-9. 2007..Our objective was to determine whether sex and age are associated with differences in admission practices, processes of care and clinical outcomes for critically ill patients... - Clinical review: critical care in the global context--disparities in burden of illness, access, and economicsRobert A Fowler
Department of Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room D478, Toronto, ON, Canada M4N 3M5
Crit Care 12:225. 2008.... - Early observational research and registries during the 2009-2010 influenza A pandemicRobert A Fowler
Canadian Critical Care Trials Group, Toronto, Ontario, Canada
Crit Care Med 38:e120-32. 2010.... - Transmission of severe acute respiratory syndrome during intubation and mechanical ventilationRobert A Fowler
Interdepartmental Division of Critical Care Medicine, University of Toronto, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
Am J Respir Crit Care Med 169:1198-202. 2004..74; 95% CI, 0.11 to 4.92; p = 0.6) compared with their respective reference cohorts. Specific infection control recommendations concerning the care of critically ill patients may help limit further nosocomial transmission... - Early massive transfusion in trauma patients: Canadian single-centre retrospective cohort studyTushar D Mahambrey
Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Can J Anaesth 56:740-50. 2009..To determine associations between red blood cell (RBC) transfusion and early and late clinical outcomes in massively transfused adult trauma patients... - Critical care and the global burden of critical illness in adultsNeill K J Adhikari
Interdepartmental Division of Critical Care, University of Toronto and Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
Lancet 376:1339-46. 2010.... - 2009 influenza A (H1N1): a clinical reviewJesse W Delaney
University of Toronto Department of Medicine, Toronto, ON, Canada
Hosp Pract (1995) 38:74-81. 2010..With optimal care, mortality rates range from 5% to 7% among those hospitalized and reach approximately 20% among those admitted to the intensive care unit... - Screening and prevention of venous thromboembolism in critically ill patients: a decision analysis and economic evaluationSachin Sud
Trillium Health Center, Mississauga, Ontario, Canada
Am J Respir Crit Care Med 184:1289-98. 2011..Venous thromboembolism is difficult to diagnose in critically ill patients and may increase morbidity and mortality... - Patient and healthcare professional factors influencing end-of-life decision-making during critical illness: a systematic reviewDavid W Frost
Division of General Internal Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada
Crit Care Med 39:1174-89. 2011..DATA SOURCES, SELECTION, AND ABSTRACTION: We conducted a structured search of Ovid Medline for interventional and observational research articles incorporating critical care and end-of-life decision-making terms... - Has mortality from acute respiratory distress syndrome decreased over time?: A systematic reviewJason Phua
F R C P C, Toronto Western Hospital, 399 Bathurst Street, 2MCL 411M, Toronto, ON M5T 2S8, Canada
Am J Respir Crit Care Med 179:220-7. 2009..It is commonly stated that mortality from acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) is decreasing... - Blood conservation for critically ill patientsRobert A Fowler
Sunnybrook and Women s College Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
Crit Care Clin 20:313-24, x. 2004.... - Knowledge translation in critical care: factors associated with prescription of commonly recommended best practices for critically ill patientsRoy Ilan
Sunnybrook Health Sciences Centre, Toronto, ON, Canada
Crit Care Med 35:1696-702. 2007.... - Risk factors associated with resistance to ciprofloxacin in clinical bacterial isolates from intensive care unit patientsPhillip D Levin
Department of Critical Care, Sunnybrook Health Sciences Centre, B121 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
Infect Control Hosp Epidemiol 28:331-6. 2007..To determine risk factors and outcomes associated with ciprofloxacin resistance in clinical bacterial isolates from intensive care unit (ICU) patients... - A multifaceted intervention for quality improvement in a network of intensive care units: a cluster randomized trialDamon C Scales
Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada
JAMA 305:363-72. 2011..Evidence-based practices improve intensive care unit (ICU) outcomes, but eligible patients may not receive them. Community hospitals treat most critically ill patients but may have few resources dedicated to quality improvement... - Cost-effectiveness of defending against bioterrorism: a comparison of vaccination and antibiotic prophylaxis against anthraxRobert A Fowler
Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Ann Intern Med 142:601-10. 2005..Weaponized Bacillus anthracis is one of the few biological agents that can cause death and disease in sufficient numbers to devastate an urban setting... - A long-term follow-up study investigating health-related quality of life and resource use in survivors of severe sepsis: comparison of recombinant human activated protein C with standard careChristopher J Longo
McMaster University, Main Street West, Hamilton, Ontario, Canada, L8S 4M4
Crit Care 11:R128. 2007..The objective of this study was to evaluate prospectively the effect of APC on long-term HRQoL and resource utilization compared with a nonrandomized control group that received standard care... - Impact of interhospital transfer on outcomes for trauma patients: a systematic reviewAndrea D Hill
Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
J Trauma 71:1885-900; discussion 1901. 2011..The purpose of this study was to systematically review the current evidence of the association between transfer status and outcomes for patients... - Utility and safety of draining pleural effusions in mechanically ventilated patients: a systematic review and meta-analysisEwan C Goligher
Interdepartmental Division of Critical Care, Mount Sinai Hospital and the University Health Network, University of Toronto, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada
Crit Care 15:R46. 2011..Pleural effusions are frequently drained in mechanically ventilated patients but the benefits and risks of this procedure are not well established... - Is a mass immunization program for pandemic (H1N1) 2009 good value for money? Evidence from the Canadian ExperienceBeate Sander
Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada
Vaccine 28:6210-20. 2010.... - Prolonged time to alarm in infusion devices operated at low flow ratesRoy Ilan
Department of Medicine, Queen s University and Kingston General Hospital, Kingston, ON, Canada
Crit Care Med 36:2763-5. 2008..To evaluate the time to occlusion alarm for peristaltic infusion devices used in Toronto adult critical care units... - Cost-effectiveness of recombinant human activated protein C and the influence of severity of illness in the treatment of patients with severe sepsisRobert A Fowler
Division of General Medicine and Critical Care Medicine, Department of Medicine, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Ontario, Canada
J Crit Care 18:181-91; discussion 191-4. 2003..To evaluate the cost-effectiveness of recombinant human activated protein C (rhAPC) compared with usual therapy for patients with severe sepsis, and also to determine the influence that severity of illness exerts on cost-effectiveness... - Implementation of a research awareness program in the critical care unit: effects on families and cliniciansCraig Dale
Trauma, Emergency and Critical Care Program, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
Intensive Crit Care Nurs 26:69-74. 2010..Successful conduct of research studies in the critically ill requires communication with families, substitute decision-makers and clinicians... - Critically ill patients with severe acute respiratory syndromeRobert A Fowler
Interdepartmental Division of Critical Care Medicine, University of Toronto, Ontario
JAMA 290:367-73. 2003..Affected patients had primarily single-organ respiratory failure, and half of mechanically ventilated patients died. The SARS outbreak greatly strained regional critical care resources... - The optimal timing of intestinal transplantation for children with intestinal failure: a Markov analysisSteven R Lopushinsky
Department of Surgery, Hospital for Sick Children, Toronto, Ontario, Canada
Ann Surg 246:1092-9. 2007..Identify an optimal approach to the timing of intestinal transplantation for children dependent on total parenteral nutrition (PN)... - Blood conservation in the intensive care unitRobert A Fowler
Department of Medicine and Interdepartmental Division of Critical Care Medicine, Sunnybrook and Women's College Health Sciences Centre, Toronto, Ontario, Canada
Crit Care Med 31:S715-20. 2003..The effects of these strategies on phlebotomy volumes, hemoglobin and hematocrit levels, transfusion requirements, clinical outcomes, as well as intensive care unit and laboratory resources and costs should be further evaluated... - Eligibility criteria of randomized controlled trials published in high-impact general medical journals: a systematic sampling reviewHarriette G C Van Spall
Department of Medicine, University of Toronto, Toronto, Ontario
JAMA 297:1233-40. 2007..Selective eligibility criteria of randomized controlled trials (RCTs) are vital to trial feasibility and internal validity. However, the exclusion of certain patient populations may lead to impaired generalizability of results... - Variability in antibiotic prescribing patterns and outcomes in patients with clinically suspected ventilator-associated pneumoniaRobert A Fowler
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Stanford University School of Medicine, USA
Chest 123:835-44. 2003.... - The arc of the pulmonary artery catheterRobert A Fowler
JAMA 290:2732-4. 2003 - Evidence of airborne transmission of SARSRobert A Fowler
N Engl J Med 351:609-11; author reply 609-11. 2004 - Insights from PAC-Man on flow-monitoring devices: curb your enthusiasmMauricio Ferri
Crit Care Med 36:1953-4. 2008 - Dispersal of respiratory droplets with open vs closed oxygen delivery masks: implications for the transmission of severe acute respiratory syndromeRon Somogyi
University Health Network, Toronto General Hospital, Canada
Chest 125:1155-7. 2004..Maintaining respiratory isolation during the administration of oxygen may reduce the risk of the nosocomial transmission of respiratory infections such as SARS...