Robert A Fowler

Summary

Affiliation: Sunnybrook Health Sciences Centre
Country: Canada

Publications

  1. pmc Acute kidney injury among critically ill patients with pandemic H1N1 influenza A in Canada: cohort study
    Sean M Bagshaw
    Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 3C1 12 Walter C Mackenzie Centre, 8440 112 St NW, Edmonton, AB T6G 2B7, Canada
    BMC Nephrol 14:123. 2013
  2. pmc Clinical and temporal patterns of severe pneumonia causing critical illness during Hajj
    Yasser Mandourah
    Department of Intensive Care, Riyadh Military Hospital, P O Box 789711159, Riyadh, Kingdom of Saudi Arabia
    BMC Infect Dis 12:117. 2012
  3. ncbi request reprint End-of-life care in Canada
    Robert Fowler
    Departments of Medicine and Critical Care Medicine, Sunnybrook Hospital, Toronto, Ontario, Canada M4N 3M5
    Clin Invest Med 36:E127-32. 2013
  4. pmc Duration of antibiotic therapy for bacteremia: a systematic review and meta-analysis
    Thomas C Havey
    Department of Medicine, University of Toronto, 1 Kings College Circle, O, M5S 1A8, Canada
    Crit Care 15:R267. 2011
  5. pmc When should a diagnosis of influenza be considered in adults requiring intensive care unit admission? Results of population-based active surveillance in Toronto
    Stefan P Kuster
    Mount Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada
    Crit Care 15:R182. 2011
  6. pmc Critical care resources in the Solomon Islands: a cross-sectional survey
    Mia Westcott
    George Institute For Global Health, PO Box M201, Missenden Road Sydney, NSW 2050, Australia
    BMC Int Health Hum Rights 12:1. 2012
  7. pmc A Canadian Critical Care Trials Group project in collaboration with the international forum for acute care trialists - Collaborative H1N1 Adjuvant Treatment pilot trial (CHAT): study protocol and design of a randomized controlled trial
    Karen E A Burns
    Interdepartmental Division of Critical Care Medicine and Departments of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    Trials 12:70. 2011
  8. pmc Oncoming tides in the Age(ing) of Aquarius
    David W Frost
    Department of Medicine and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto M4N 3M5, Canada
    Crit Care 13:145. 2009
  9. pmc Venous thromboembolism and bleeding in critically ill patients with severe renal insufficiency receiving dalteparin thromboprophylaxis: prevalence, incidence and risk factors
    Deborah Cook
    Department of Medicine, 1200 Main Street, McMaster University, Hamilton, Canada
    Crit Care 12:R32. 2008
  10. pmc Multi-drug resistant Acinetobacter infections in critically injured Canadian forces soldiers
    Homer C Tien
    The Trauma Program, and Department of Surgery, Sunnybrook Health Sciences Centre, H186 2075 Bayview Avenue, Toronto, Canada, M4N 3M5
    BMC Infect Dis 7:95. 2007

Collaborators

Detail Information

Publications48

  1. pmc Acute kidney injury among critically ill patients with pandemic H1N1 influenza A in Canada: cohort study
    Sean M Bagshaw
    Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 3C1 12 Walter C Mackenzie Centre, 8440 112 St NW, Edmonton, AB T6G 2B7, Canada
    BMC Nephrol 14:123. 2013
    ..Our objective was to describe the incidence of AKI (acute kidney injury) in these patients and risk factors for AKI, renal replacement therapy (RRT), and mortality...
  2. pmc Clinical and temporal patterns of severe pneumonia causing critical illness during Hajj
    Yasser Mandourah
    Department of Intensive Care, Riyadh Military Hospital, P O Box 789711159, Riyadh, Kingdom of Saudi Arabia
    BMC Infect Dis 12:117. 2012
    ..We describe the number and temporal onset, co-morbidities, and outcomes of severe pneumonia causing critical illness among pilgrims...
  3. ncbi request reprint End-of-life care in Canada
    Robert Fowler
    Departments of Medicine and Critical Care Medicine, Sunnybrook Hospital, Toronto, Ontario, Canada M4N 3M5
    Clin Invest Med 36:E127-32. 2013
    ..Herein we provide a brief overview of the end-of-life care in the Canadian context, and highlight challenges and opportunities for health care system change in the coming decades...
  4. pmc Duration of antibiotic therapy for bacteremia: a systematic review and meta-analysis
    Thomas C Havey
    Department of Medicine, University of Toronto, 1 Kings College Circle, O, M5S 1A8, Canada
    Crit Care 15:R267. 2011
    ....
  5. pmc When should a diagnosis of influenza be considered in adults requiring intensive care unit admission? Results of population-based active surveillance in Toronto
    Stefan P Kuster
    Mount Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada
    Crit Care 15:R182. 2011
    ....
  6. pmc Critical care resources in the Solomon Islands: a cross-sectional survey
    Mia Westcott
    George Institute For Global Health, PO Box M201, Missenden Road Sydney, NSW 2050, Australia
    BMC Int Health Hum Rights 12:1. 2012
    ..abstract:..
  7. pmc A Canadian Critical Care Trials Group project in collaboration with the international forum for acute care trialists - Collaborative H1N1 Adjuvant Treatment pilot trial (CHAT): study protocol and design of a randomized controlled trial
    Karen E A Burns
    Interdepartmental Division of Critical Care Medicine and Departments of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    Trials 12:70. 2011
    ....
  8. pmc Oncoming tides in the Age(ing) of Aquarius
    David W Frost
    Department of Medicine and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto M4N 3M5, Canada
    Crit Care 13:145. 2009
    ....
  9. pmc Venous thromboembolism and bleeding in critically ill patients with severe renal insufficiency receiving dalteparin thromboprophylaxis: prevalence, incidence and risk factors
    Deborah Cook
    Department of Medicine, 1200 Main Street, McMaster University, Hamilton, Canada
    Crit Care 12:R32. 2008
    ..The objective of the present study was to evaluate the prevalence, incidence and predictors of DVT and the incidence of bleeding in intensive care unit (ICU) patients with estimated creatinine clearance <30 ml/min...
  10. pmc Multi-drug resistant Acinetobacter infections in critically injured Canadian forces soldiers
    Homer C Tien
    The Trauma Program, and Department of Surgery, Sunnybrook Health Sciences Centre, H186 2075 Bayview Avenue, Toronto, Canada, M4N 3M5
    BMC Infect Dis 7:95. 2007
    ..Military members, injured in Afghanistan or Iraq, have returned home with multi-drug resistant Acinetobacter baumannii infections. The source of these infections is unknown...
  11. pmc Early observational research and registries during the 2009-2010 influenza A pandemic
    Robert A Fowler
    Canadian Critical Care Trials Group, Toronto, Ontario, Canada
    Crit Care Med 38:e120-32. 2010
    ....
  12. pmc Clinical review: critical care in the global context--disparities in burden of illness, access, and economics
    Robert A Fowler
    Department of Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room D478, Toronto, ON, Canada M4N 3M5
    Crit Care 12:225. 2008
    ....
  13. pmc Sex-and age-based differences in the delivery and outcomes of critical care
    Robert A Fowler
    Interdepartmental Division of Critical Care Medicine and Department of Medicine, University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ont
    CMAJ 177:1513-9. 2007
    ..Our objective was to determine whether sex and age are associated with differences in admission practices, processes of care and clinical outcomes for critically ill patients...
  14. doi request reprint Update in critical care 2007
    Robert A Fowler
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada
    Am J Respir Crit Care Med 177:808-19. 2008
  15. doi request reprint Sex and critical illness
    Robert A Fowler
    Department of Medicine, Interdepartmental Division of Critical Care Medicine, University of Toronto, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Curr Opin Crit Care 15:442-9. 2009
    ..The article reviews and speculates on potential mechanisms underlying sex-related differences in admission patterns, care delivery and outcome of critical illness...
  16. ncbi request reprint Transmission of severe acute respiratory syndrome during intubation and mechanical ventilation
    Robert A Fowler
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Am J Respir Crit Care Med 169:1198-202. 2004
    ..74; 95% CI, 0.11 to 4.92; p = 0.6) compared with their respective reference cohorts. Specific infection control recommendations concerning the care of critically ill patients may help limit further nosocomial transmission...
  17. doi request reprint Early massive transfusion in trauma patients: Canadian single-centre retrospective cohort study
    Tushar D Mahambrey
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Can J Anaesth 56:740-50. 2009
    ..To determine associations between red blood cell (RBC) transfusion and early and late clinical outcomes in massively transfused adult trauma patients...
  18. doi request reprint Critical care and the global burden of critical illness in adults
    Neill K J Adhikari
    Interdepartmental Division of Critical Care, University of Toronto and Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    Lancet 376:1339-46. 2010
    ....
  19. doi request reprint Patient and healthcare professional factors influencing end-of-life decision-making during critical illness: a systematic review
    David W Frost
    Division of General Internal Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Crit Care Med 39:1174-89. 2011
    ..DATA SOURCES, SELECTION, AND ABSTRACTION: We conducted a structured search of Ovid Medline for interventional and observational research articles incorporating critical care and end-of-life decision-making terms...
  20. doi request reprint Tracheostomy timing in traumatic brain injury: A propensity-matched cohort study
    Aziz S Alali
    From the Sunnybrook Research Institute A S A, D C S, R A F, A K, C D M, A B N, Department of Critical Care D C S, R A F, Division of Neurosurgery T G M, Department of Research Design and Biostatistics A K, and Department of Surgery A B N, Sunnybrook Health Sciences Center Clinical Epidemiology Program A S A, D C S, R A F, J G R, A K, A B N, Institute of Health Policy, Management and Evaluation, Interdepartmental Division of Critical Care D C S, R A F, and Keenan Research Centre of the Li Ka Shing Knowledge Institute J G R, A B N and Department of Medicine J G R, St Michael s Hospital, University of Toronto, Toronto and Division of Neurosurgery A S A, University of Ottawa, Ottawa, Ontario, Canada
    J Trauma Acute Care Surg 76:70-8. 2014
    ....
  21. ncbi request reprint 2009 influenza A (H1N1): a clinical review
    Jesse W Delaney
    University of Toronto Department of Medicine, Toronto, ON, Canada
    Hosp Pract (1995) 38:74-81. 2010
    ..With optimal care, mortality rates range from 5% to 7% among those hospitalized and reach approximately 20% among those admitted to the intensive care unit...
  22. doi request reprint Screening and prevention of venous thromboembolism in critically ill patients: a decision analysis and economic evaluation
    Sachin Sud
    Trillium Health Center, Mississauga, Ontario, Canada
    Am J Respir Crit Care Med 184:1289-98. 2011
    ..Venous thromboembolism is difficult to diagnose in critically ill patients and may increase morbidity and mortality...
  23. doi request reprint Has mortality from acute respiratory distress syndrome decreased over time?: A systematic review
    Jason Phua
    F R C P C, Toronto Western Hospital, 399 Bathurst Street, 2MCL 411M, Toronto, ON M5T 2S8, Canada
    Am J Respir Crit Care Med 179:220-7. 2009
    ..It is commonly stated that mortality from acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) is decreasing...
  24. ncbi request reprint Blood conservation for critically ill patients
    Robert A Fowler
    Sunnybrook and Women s College Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Crit Care Clin 20:313-24, x. 2004
    ....
  25. ncbi request reprint Knowledge translation in critical care: factors associated with prescription of commonly recommended best practices for critically ill patients
    Roy Ilan
    Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    Crit Care Med 35:1696-702. 2007
    ....
  26. doi request reprint Effect of selective decontamination on antimicrobial resistance in intensive care units: a systematic review and meta-analysis
    Nick Daneman
    Trauma, Emergency, and Critical Care Program, Sunnybrook Health Sciences Centre, University of Toronto, ON, Canada
    Lancet Infect Dis 13:328-41. 2013
    ..We aimed to assess the effect of SDD and SOD on antimicrobial resistance rates in patients in ICUs...
  27. ncbi request reprint Cost-effectiveness of defending against bioterrorism: a comparison of vaccination and antibiotic prophylaxis against anthrax
    Robert A Fowler
    Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Ann Intern Med 142:601-10. 2005
    ..Weaponized Bacillus anthracis is one of the few biological agents that can cause death and disease in sufficient numbers to devastate an urban setting...
  28. ncbi request reprint Risk factors associated with resistance to ciprofloxacin in clinical bacterial isolates from intensive care unit patients
    Phillip D Levin
    Department of Critical Care, Sunnybrook Health Sciences Centre, B121 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Infect Control Hosp Epidemiol 28:331-6. 2007
    ..To determine risk factors and outcomes associated with ciprofloxacin resistance in clinical bacterial isolates from intensive care unit (ICU) patients...
  29. doi request reprint A multifaceted intervention for quality improvement in a network of intensive care units: a cluster randomized trial
    Damon C Scales
    Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada
    JAMA 305:363-72. 2011
    ..Evidence-based practices improve intensive care unit (ICU) outcomes, but eligible patients may not receive them. Community hospitals treat most critically ill patients but may have few resources dedicated to quality improvement...
  30. pmc A long-term follow-up study investigating health-related quality of life and resource use in survivors of severe sepsis: comparison of recombinant human activated protein C with standard care
    Christopher J Longo
    McMaster University, Main Street West, Hamilton, Ontario, Canada, L8S 4M4
    Crit Care 11:R128. 2007
    ..The objective of this study was to evaluate prospectively the effect of APC on long-term HRQoL and resource utilization compared with a nonrandomized control group that received standard care...
  31. doi request reprint Impact of acute stress on resident performance during simulated resuscitation episodes: a prospective randomized cross-over study
    Dominique Piquette
    a Department of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada
    Teach Learn Med 26:9-16. 2014
    ..This anticipatory stressful response could impact on resident learning and performance and should be further explored. ..
  32. doi request reprint Impact of interhospital transfer on outcomes for trauma patients: a systematic review
    Andrea D Hill
    Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
    J Trauma 71:1885-900; discussion 1901. 2011
    ..The purpose of this study was to systematically review the current evidence of the association between transfer status and outcomes for patients...
  33. pmc Utility and safety of draining pleural effusions in mechanically ventilated patients: a systematic review and meta-analysis
    Ewan C Goligher
    Interdepartmental Division of Critical Care, Mount Sinai Hospital and the University Health Network, University of Toronto, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada
    Crit Care 15:R46. 2011
    ..Pleural effusions are frequently drained in mechanically ventilated patients but the benefits and risks of this procedure are not well established...
  34. ncbi request reprint Cost-effectiveness of recombinant human activated protein C and the influence of severity of illness in the treatment of patients with severe sepsis
    Robert A Fowler
    Division of General Medicine and Critical Care Medicine, Department of Medicine, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Ontario, Canada
    J Crit Care 18:181-91; discussion 191-4. 2003
    ..To evaluate the cost-effectiveness of recombinant human activated protein C (rhAPC) compared with usual therapy for patients with severe sepsis, and also to determine the influence that severity of illness exerts on cost-effectiveness...
  35. doi request reprint Is a mass immunization program for pandemic (H1N1) 2009 good value for money? Evidence from the Canadian Experience
    Beate Sander
    Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada
    Vaccine 28:6210-20. 2010
    ....
  36. doi request reprint Prolonged time to alarm in infusion devices operated at low flow rates
    Roy Ilan
    Department of Medicine, Queen s University and Kingston General Hospital, Kingston, ON, Canada
    Crit Care Med 36:2763-5. 2008
    ..To evaluate the time to occlusion alarm for peristaltic infusion devices used in Toronto adult critical care units...
  37. doi request reprint Implementation of a research awareness program in the critical care unit: effects on families and clinicians
    Craig Dale
    Trauma, Emergency and Critical Care Program, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    Intensive Crit Care Nurs 26:69-74. 2010
    ..Successful conduct of research studies in the critically ill requires communication with families, substitute decision-makers and clinicians...
  38. ncbi request reprint Critically ill patients with severe acute respiratory syndrome
    Robert A Fowler
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Ontario
    JAMA 290:367-73. 2003
    ..Severe acute respiratory syndrome (SARS) is a newly recognized infectious disease capable of causing severe respiratory failure...
  39. pmc Intracranial pressure monitoring in severe traumatic brain injury: results from the American College of Surgeons Trauma Quality Improvement Program
    Aziz S Alali
    1 Sunnybrook Research Institute, Sunnybrook Health Sciences Center, Toronto, Ontario, Canada
    J Neurotrauma 30:1737-46. 2013
    ..However, variability in ICP monitoring rates contributed only modestly to variability in institutional mortality rates. Identifying other institutional practices that impact on mortality is an important area for future research...
  40. ncbi request reprint The optimal timing of intestinal transplantation for children with intestinal failure: a Markov analysis
    Steven R Lopushinsky
    Department of Surgery, Hospital for Sick Children, Toronto, Ontario, Canada
    Ann Surg 246:1092-9. 2007
    ..Identify an optimal approach to the timing of intestinal transplantation for children dependent on total parenteral nutrition (PN)...
  41. ncbi request reprint Blood conservation in the intensive care unit
    Robert A Fowler
    Department of Medicine and Interdepartmental Division of Critical Care Medicine, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Crit Care Med 31:S715-20. 2003
    ..To describe blood conservation strategies for critically ill patients...
  42. doi request reprint Effects of clinical supervision on resident learning and patient care during simulated ICU scenarios
    Dominique Piquette
    1Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada 2Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada 3Wilson Centre for Research in Education, University of Toronto, Toronto, ON, Canada 4Department of Anesthesia, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada 5Faculty of Medicine, Centre for Health Education Scholarship, University of British Columbia, Vancouver, BC, Canada
    Crit Care Med 41:2705-11. 2013
    ..The objective of this study was to determine the effects of closer supervision on patient care, resident participation, and the development of resident ability to care independently for critically ill patients during simulated scenarios...
  43. ncbi request reprint Eligibility criteria of randomized controlled trials published in high-impact general medical journals: a systematic sampling review
    Harriette G C Van Spall
    Department of Medicine, University of Toronto, Toronto, Ontario
    JAMA 297:1233-40. 2007
    ..Selective eligibility criteria of randomized controlled trials (RCTs) are vital to trial feasibility and internal validity. However, the exclusion of certain patient populations may lead to impaired generalizability of results...
  44. ncbi request reprint Variability in antibiotic prescribing patterns and outcomes in patients with clinically suspected ventilator-associated pneumonia
    Robert A Fowler
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, Stanford University School of Medicine, USA
    Chest 123:835-44. 2003
    ....
  45. ncbi request reprint The arc of the pulmonary artery catheter
    Robert A Fowler
    JAMA 290:2732-4. 2003
  46. doi request reprint Insights from PAC-Man on flow-monitoring devices: curb your enthusiasm
    Mauricio Ferri
    Crit Care Med 36:1953-4. 2008
  47. ncbi request reprint Dispersal of respiratory droplets with open vs closed oxygen delivery masks: implications for the transmission of severe acute respiratory syndrome
    Ron Somogyi
    University Health Network, Toronto General Hospital, Canada
    Chest 125:1155-7. 2004
    ..Maintaining respiratory isolation during the administration of oxygen may reduce the risk of the nosocomial transmission of respiratory infections such as SARS...
  48. ncbi request reprint Evidence of airborne transmission of SARS
    Robert A Fowler
    N Engl J Med 351:609-11; author reply 609-11. 2004