Research Topics
Species | F S FosterSummaryAffiliation: Sunnybrook and Women's College Health Sciences Centre Country: Canada Publications
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Detail Information
Publications
Experimental characterization of fundamental and second harmonic beams for a high-frequency ultrasound transducerEmmanuel W Cherin
Imag Res, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Ultrasound Med Biol 28:635-46. 2002..59 mm. The harmonic beam showed a 3-dB decrease in side lobe levels. Preliminary second harmonic images of mouse tissue in vitro are presented and compared to fundamental imaging at 20 and 40 MHz...- In vivo imaging of embryonic development in the mouse eye by ultrasound biomicroscopyF Stuart Foster
Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Invest Ophthalmol Vis Sci 44:2361-6. 2003..In this study, normal embryonic development of the mouse eye was studied by ultrasound biomicroscopy (UBM), with a focus on the formation of the retina, lens, and cornea... - Dynamic measurement of internal solid displacement in articular cartilage using ultrasound backscatterManuel Fortin
Department of Chemical Engineering, Institute of Biomedical Engineering, Ecole Polytechnique de Montreal, P.O.Box 6079, Station Centre-ville, Que, H3C 3A7, Montreal, Canada
J Biomech 36:443-7. 2003..4 (depending on compression speed), followed by contraction to lower values. A more restricted movement was observed at both the articular surface and near to the subchondral bone than at regions midway between these two locations... - In vivo assessment of postnatal murine ocular development by ultrasound biomicroscopyAllison S Brown
Department of Imaging Research, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
Curr Eye Res 30:45-51. 2005..Ultrasound biomicroscopy (UBM) can noninvasively provide anatomical information about mouse ocular structures. We present the quantitation of postnatal murine eye development using UBM... - Performance and characterization of new micromachined high-frequency linear arraysMarc Lukacs
Imaging Research, Sunnybrook and Women s College Health Science Centre, University of Toronto, Toronto, ON M4N 3M5, Canada
IEEE Trans Ultrason Ferroelectr Freq Control 53:1719-29. 2006..Any significant deviation from simulation can be explained through limitations in apparatus calibration and in device packaging... - A new ultrasound instrument for in vivo microimaging of miceF S Foster
Dept of Medical Biophysics, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Ultrasound Med Biol 28:1165-72. 2002..Noninvasive UBM assessment of development shows striking similarity to invasive atlases of mouse anatomy. The most detailed noninvasive in vivo images of mouse embryonic development achieved using any imaging method are presented... - Ultrasound for the visualization and quantification of tumor microcirculationF S Foster
Sunnybrook and Women s College Health Sciences Centre and the University of Toronto, Ontario, Canada
Cancer Metastasis Rev 19:131-8. 2000..The strengths and weaknesses of these new methods are discussed and the potential for their use in preclinical animal drug studies, clinical drug trials, and prognostic studies is described... - High-frequency color flow imaging of the microcirculationD E Goertz
Department of Medical Biophysics, University of Toronto, Ontario, Canada
Ultrasound Med Biol 26:63-71. 2000..Further experiments examining experimental murine tumors confirmed the successful detection of flow in the tumor microcirculation... 
A method for differentiating targeted microbubbles in real time using subharmonic micro-ultrasound and interframe filteringA Needles
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Ultrasound Med Biol 35:1564-73. 2009....- Advances in ultrasound biomicroscopyF S Foster
Sunnybrook Health Science Centre and Department of Medical Biophysics, University of Toronto, Ontario, Canada
Ultrasound Med Biol 26:1-27. 2000..Ultrasound biomicroscopic studies of mouse embryonic development and tumour biology are presented. Speculation on the continuing evolution of ultrasound biomicroscopy will be discussed... - High-frequency subharmonic pulsed-wave Doppler and color flow imaging of microbubble contrast agentsA Needles
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Ultrasound Med Biol 34:1139-51. 2008.... - Nonlinear contrast imaging with an array-based micro-ultrasound systemA Needles
VisualSonics Inc, Toronto, Ontario, Canada
Ultrasound Med Biol 36:2097-106. 2010.... - Ultrasonic detection and developmental changes in calcification of the placenta during normal pregnancy in miceC Akirav
Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada
Placenta 26:129-37. 2005..These deposits provide an ultrasound detectable marker of the maternal-placental interface that is particularly prominent during the establishment of the chorio-allantoic placenta between days 7.5 and 9.5 of gestation... - High-frequency intracoronary ultrasound imagingF S Foster
Sunnybrook Health Science Centre, Toronto, Ontario, Canada
Semin Interv Cardiol 2:33-41. 1997..There would appear to be no fundamental reason why frequencies in excess of 50 MHz could not be implemented. Studies using prototype IVUS instruments in the 50 MHz range demonstrate significant improvements in image quality... - Quantifying tissue damage due to focused ultrasound heating observed by MRIS J Graham
Sunnybrook and Women s College Health Sciences Centre, and Department of Medical Biophysics, University of Toronto, Ontario, Canada
Magn Reson Med 41:321-8. 1999..These results suggest that quantitative MR guidance of thermal coagulation therapy is feasible, and they provide information useful for designing future investigations in vivo... - Use of microbubble ultrasound contrast agent to demonstrate the iris valve effect in human eye bank eyesC J Pavlin
Department of Ophthalmology, Ontario Cancer Institute, Princess Margaret Hospital, University of Toronto, Canada
Am J Ophthalmol 126:719-20. 1998..To demonstrate that the interface between the normal iris and the lens surface functions as a flap valve... - Interdigital pair bonding for high frequency (20-50 MHz) ultrasonic composite transducersR Liu
Imaging and Bioengineering, Sunnybrook and Women's College Health Sciences Centre, University of Toronto, Toronto, Ontario M4N 3M5, Canada
IEEE Trans Ultrason Ferroelectr Freq Control 48:299-306. 2001.... - Design and fabrication of ultrafine piezoelectric compositesJ Yin
Imaging Research, Sunnybrook and Women s College Health Science Centre, University of Toronto, Toronto, ON M1V 3A5, Canada
Ultrason Imaging 27:54-64. 2005..6 and that there are no noticeable lateral resonances in the frequency range of 55-150 MHz. Design criteria for fine scale elements are also discussed based on theoretical results from finite element analysis (FEA)... - In vitro characterization of the subharmonic ultrasound signal from Definity microbubbles at high frequenciesK Cheung
Imaging Research, Sunnybrook Health Sciences Centre University of Toronto, Toronto, Canada
Phys Med Biol 53:1209-23. 2008..2 microm, respectively. Definity may be a suitable ultrasound contrast agent for subharmonic imaging at 20 MHz with peak-negative pressures between 380 and 590 kPa and pulses greater than or equal to four cycles in duration... 
Use of a high frequency ultrasound microscope to image the action of 2-nitroimidazoles in multicellular spheroidsL R Bérubé
Ontario Cancer Institute, Toronto, Canada
Br J Cancer 65:633-40. 1992..The present work demonstrates the potential usefulness of ultrasound backscatter microscopy in following the action of selected drugs in this in vitro tumour model...- Applications for multifrequency ultrasound biomicroscopy in mice from implantation to adulthoodY Q Zhou
Samuel Lunenfeld Research Institute at Mount Sinai Hospital, Toronto, Ontario, Canada, M5G 1X5
Physiol Genomics 10:113-26. 2002.... - In vitro and in vivo comparison of three different intravascular ultrasound catheter designsS Fort
Schulich Heart Centre, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Ontario, Canada
Catheter Cardiovasc Interv 52:382-92. 2001..There were also small but potentially important differences with regards to clinical events and complications associated with the use of the different IVUS catheters during the PCI procedures, reflecting differences in catheter design... - Model for the ultrasound reflection from micro-beads and cells distributed in layers on a uniform surfaceO Couture
Imaging Research, Sunnybrook Health Sciences Centre University of Toronto, Toronto, Canada
Phys Med Biol 52:4189-204. 2007..The use of such a model could lead to a better understanding of the structures observed in layered tissue images... - Feasibility of linear arrays for interstitial ultrasound thermal therapyR Chopra
Sunnybrook and Women s College Health Sciences Centre and Department of Medical Biophysics, University of Toronto, Ontario, Canada
Med Phys 27:1281-6. 2000..Single element transducers produced excessive heating near the probe surface. Homogeneous blood flow is predicted to reduce the mean temperature within the heated region, with little effect on the spatial pattern... - High frequency acoustic parameters of human and bovine articular cartilage following experimentally-induced matrix degradationG A Joiner
Department of Medical Biophysics, University of Toronto, Sunnybrook and Women's College Health Sciences Centre, ON, Canada
Ultrason Imaging 23:106-16. 2001..These findings suggest that ultrasound can potentially be used to detect morphologic changes in articular cartilage associated with the progression of osteoarthritis... - Ultrahigh frame rate retrospective ultrasound microimaging and blood flow visualization in mice in vivoEmmanuel Cherin
Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
Ultrasound Med Biol 32:683-91. 2006..This technology enables detailed in vivo biomechanical studies of dynamic tissues such as the myocardium of the mouse heart with high temporal resolution... - Fabrication and performance of a 40-MHz linear array based on a 1-3 composite with geometric elevation focusingJeremy A Brown
Sunnybrook Health Sciences Centre, Toronto, ON, Canada
IEEE Trans Ultrason Ferroelectr Freq Control 54:1888-94. 2007..A -3 dB one-way beamwidth of 97 microm was found at a depth of 6 mm. The one-way radiation pattern decreased smoothly to less than -30 dB at a lateral distance of 640 microm... - Golay pulse encoding for microbubble contrast imaging in ultrasoundClaudia Leavens
Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada
IEEE Trans Ultrason Ferroelectr Freq Control 54:2082-90. 2007.... - Noninvasive ultrasonic measurement of regional and local pulse-wave velocity in miceRoss Williams
Sunnybrook Health Sciences Centre, Toronto, ON, Canada
Ultrasound Med Biol 33:1368-75. 2007..80, p<0.001). The mean difference between methods was 0.05+/-0.21 m/s. This study demonstrates the feasibility of measuring both regional and local PWV in mice using image-based high-frequency ultrasound methodologies... - Microultrasound molecular imaging of vascular endothelial growth factor receptor 2 in a mouse model of tumor angiogenesisJoshua J Rychak
VisualSonics, Inc, Toronto, ON
Mol Imaging 6:289-96. 2007..These data demonstrate that contrast-enhanced microultrasound imaging is a useful method for assessing molecular expression of tumor angiogenesis in mice at high resolution... - Innovations in imaging for chronic total occlusions: a glimpse into the future of angiography's blind-spotBrian K Courtney
Division of Cardiology, Schulich Heart Program, Sunnybrook Health Sciences Centre, Room A 253, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
Eur Heart J 29:583-93. 2008..Strategies that combine imaging techniques with the use of interventional therapies may provide significant opportunities to improve results in CTO interventions and represent an active area of investigation... - Interframe clutter filtering for high frequency flow imagingAndrew Needles
Sunnybrook Health Sciences Centre, Toronto, Canada
Ultrasound Med Biol 33:591-600. 2007..Further in vivo experiments examining experimental murine tumors demonstrated the feasibility of performing HF PD and CF imaging at high frame rates using interframe filtering... - Nonlinear ultrasound propagation through layered liquid and tissue-equivalent media: computational and experimental results at high frequencyRoss Williams
Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, M4N 3M5, Canada
Phys Med Biol 51:5809-24. 2006..The results demonstrate significant nonlinear propagation effects for high frequency imaging beams... - A model for reflectivity enhancement due to surface bound submicrometer particlesOlivier Couture
Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Ultrasound Med Biol 32:1247-55. 2006..This suggests the possibility of predicting signal enhancement due to a bound contrast agent in simple geometries... - High-frequency 3-D color-flow imaging of the microcirculationDavid E Goertz
Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
Ultrasound Med Biol 29:39-51. 2003..Experiments conducted on mouse tumors successfully imaged microvessel morphology in the tumor microcirculation... - Developmental changes in left and right ventricular diastolic filling patterns in miceYu-Qing Zhou
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, and Department of Physiology, University of Toronto, Ontario, Canada M5G 1X5
Am J Physiol Heart Circ Physiol 285:H1563-75. 2003..The results suggest that diastolic function matures approximately 3 wk postnatally, presumably in association with maturation of ventricular recoil and relaxation mechanisms... - Multifrequency ultrasound transducers for conformal interstitial thermal therapyRajiv Chopra
Sunnybrook and Women s College Health Sciences Centre, Department of Medical Biophysics, University of Toronto, Toronto, ON M4N 3M5, Canada
IEEE Trans Ultrason Ferroelectr Freq Control 50:881-9. 2003..Practical interstitial designs that enable the generation of shaped thermal lesions are feasible... - Developmental changes in integrated ultrasound backscatter from embryonic blood in vivo in mice at high US frequencyJohann Le Floc'h
Department of Medical Biophysics, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ont, Canada
Ultrasound Med Biol 30:1307-19. 2004..We speculate that developmental changes in red cell morphology are responsible for the observed changes in echogenicity and AIB of embryonic blood with gestational age in mice... - High frequency nonlinear B-scan imaging of microbubble contrast agentsDavid E Goertz
Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
IEEE Trans Ultrason Ferroelectr Freq Control 52:65-79. 2005..The results of this study demonstrate the feasibility of nonlinear microbubble imaging at high frequencies... - Non-invasive high-frequency vascular ultrasound elastographyRoch L Maurice
Laboratory of Biorheology and Medical Ultrasonics, Research Center, University of Montreal Hospital, , Canada
Phys Med Biol 50:1611-28. 2005..The in vivo results give confidence in the feasibility of MicroNIVE as a potential tool to non-invasively study the impact of targeted genes on vascular remodelling in rodents... - Thermal assessment of 40-MHz pulsed Doppler ultrasound in human eyeViviene Cucevic
Imaging Research, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada
Ultrasound Med Biol 31:565-73. 2005..For insonation of the lens, exposure settings no higher than nine cycles (0.225-micros pulse duration) and 10-kHz PRF should be employed and exposure time limited to minimize risk of temperature increases of 1 degree C... - High-frequency, nonlinear flow imaging of microbubble contrast agentsDavid E Goertz
IEEE Trans Ultrason Ferroelectr Freq Control 52:495-502. 2005..In vivo flow imaging of a rabbit ear microvessel was successfully performed. This work indicates the feasibility of performing flow imaging at high frequencies using nonlinear scattering from microbubbles... - Quantitation of hemodynamic function during developmental vascular regression in the mouse eyeAllison S Brown
Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Invest Ophthalmol Vis Sci 46:2231-7. 2005..Vascular development can also be assessed with high-frequency Doppler imaging, which permits detection and characterization of ocular blood flow not detectable at lower, conventional Doppler frequencies...