Research Topics
| Natalie G CoburnSummaryAffiliation: Sunnybrook Health Sciences Centre Country: Canada Publications
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Detail Information
Publications
Surgical management of intrahepatic cholangiocarcinoma--a population-based studyJensen C C Tan
Department of Surgery, Division of General Surgery, University of Toronto, Toronto, Canada
Ann Surg Oncol 15:600-8. 2008..Cholangiocarcinoma (CCA) is associated with poor survival and therapeutic nihilism. To date, there has not been an examination of the surgical management of CCA at a population level...
Surgeons' knowledge of quality indicators for gastric cancer surgeryLucy K Helyer
Department of Surgical Oncology, Princess Margaret Hospital, University Health Network, 610 University Avenue, Toronto, Ontario, M5G 2M9, Canada
Gastric Cancer 10:205-14. 2007..We hypothesize that the majority of surgeons performing gastric cancer surgery in North America are unaware of the recommended standards...
CT, MRI and ultrasound scanning rates: evaluation of cancer diagnosis, staging and surveillance in OntarioNatalie Coburn
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
J Surg Oncol 98:490-9. 2008..To examine practice patterns and rates of computed tomography (CT), magnetic resonance imaging (MRI), and abdominal ultrasound (AUS) during staging, treatment and surveillance for cancer patients...
Management of gastric cancer in OntarioNatalie G Coburn
Department of Surgery, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
J Surg Oncol 102:54-63. 2010..To describe the processes of care for gastric cancer in Ontario and identify areas in which care and possibly survival can be improved...
Lymph nodes and gastric cancerNatalie G Coburn
Division of Surgical Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
J Surg Oncol 99:199-206. 2009..Currently, surgery is the only possible cure. Nodal status is an important prognostic indicator for gastric cancer, and despite results of randomized controlled trials, debate continues over the importance of aggressive lymphadenectomy...
Evaluation of CT and MRI scanning among cancer patients in OntarioNatalie Coburn
Institute for Clinical Evaluative Sciences, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
Clin Imaging 35:301-8. 2011..This study was conducted to determine trends in utilization of CT and MRI in cancer patients in Ontario over a period of 9 years...
Treatment variation by insurance status for breast cancer patientsNatalie Coburn
University of Toronto, Division of Surgical Oncology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Breast J 14:128-34. 2008..Reduction of disparities in breast cancer presentation and treatment may be possible by increasing enrollment of uninsured, program-eligible women in a state-supported screening and treatment program...
Stage-specific effect of adjuvant therapy following gastric cancer resection: a population-based analysis of 4,041 patientsNatalie G Coburn
Department of Surgery, University of Toronto, Toronto, Ontario, Canada
Ann Surg Oncol 15:500-7. 2008..Our objective was to examine the impact of adjuvant treatment on overall survival (OS) in the general population...
Adjuvant therapy for resected gastric cancer--rapid, yet incomplete adoption following results of intergroup 0116 trialNatalie G Coburn
Department of Surgery, University of Toronto, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 70:1073-80. 2008..This study examined the adoption of adjuvant treatment following the trial results and the factors associated with its use...
Significant regional variation in adequacy of lymph node assessment and survival in gastric cancerNatalie G Coburn
Division of Surgical Oncology, Toronto Sunnybrook Regional Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Cancer 107:2143-51. 2006..The 1997 American Joint Commission on Cancer/Union Internationale Contre le Cancer guidelines were revised, requiring examination of > or =15 LN for staging...
How many lymph nodes should be assessed in patients with gastric cancer? A systematic reviewRajini Seevaratnam
Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Canada
Gastric Cancer 15:S70-88. 2012..However, the number of LNs assessed in each GC case varies, and in many cases the number examined per gastric specimen is less than current recommendations...
Population-based assessment of the surgical management of locally advanced colorectal cancerAnand Govindarajan
Division of General Surgery, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
J Natl Cancer Inst 98:1474-81. 2006..The geographic variation in the application of this procedure in patients with colon cancer suggests that local organizational structures and processes of care may play an important role in patient treatment and, therefore, prognosis...
A systematic review of patient surveillance after curative gastrectomy for gastric cancer: a brief reviewRoberta Cardoso
Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Canada
Gastric Cancer 15:S164-7. 2012..Many clinicians perform post-operative follow-up for these patients, although there is no consensus on the regimen, frequency of visits, mode of testing, or the rationale of a follow-up program...
What is the accuracy of sentinel lymph node biopsy for gastric cancer? A systematic reviewRoberta Cardoso
Division of Surgical Oncology, Sunnybrook Research Institute, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Suite T2 60, 2075 Bayview Ave, Toronto, ON, M4N 3M5, Canada
Gastric Cancer 15:S48-59. 2012..We aimed to identify and synthesize findings on the performance of SLN biopsies in gastric cancer...
Variations in surgical treatment and outcomes of patients with pancreatic cancer: a population-based studyAnand Govindarajan
Division of General Surgery, University of Toronto, Toronto, Canada
Ann Surg Oncol 15:175-85. 2008..There is ongoing debate on how variations in surgical technique affect outcomes in pancreatic cancer. This population-based study examines current surgical practice and outcomes for cancer of the pancreatic head...
A novel approach to T classification in tumor-node-metastasis staging of breast cancerNatalie G Coburn
Department of Surgical Oncology, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Ave, Suite T2-102, Toronto, Ontario, M4N 3M5 Canada
Am J Surg 192:434-8. 2006..This new T category shows a clinically and statistically significant linear relationship for both incidence of lymph node metastases and hazard ratio of death...
Multivisceral resection for gastric cancer: a systematic reviewSavtaj S Brar
Division of Surgical Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Suite T2 60, 2075 Bayview Ave, Toronto, ON, M4N 3M5, Canada
Gastric Cancer 15:S100-7. 2012..One of the most powerful predictors of outcomes in gastric cancer surgery is an R0 resection. However, the extent of the required surgical resection and the additional benefit of multivisceral resection (MVR) are controversial...
A systematic review of the accuracy and utility of peritoneal cytology in patients with gastric cancerPierre Anthony Leake
Department of Surgery, University of Toronto, Toronto, ON, Canada
Gastric Cancer 15:S27-37. 2012..In this review, we aimed to identify and synthesize findings on the use of peritoneal cytology in predicting peritoneal recurrence and overall survival in curative gastric cancer patients...
A systematic review of surgery for non-curative gastric cancerAlyson L Mahar
Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Canada
Gastric Cancer 15:S125-37. 2012....
Quality indicators for gastric cancer surgery: a survey of practicing pathologists in OntarioAlia P Qureshi
Division of General Surgery, University of Toronto, Toronto, ON, Canada
Ann Surg Oncol 16:1883-9. 2009..Because disease management is highly collaborative, we surveyed pathologists to assess their knowledge of LN assessment and margins for processing gastric cancer specimens...
Improving the quality of processing gastric cancer specimens: the pathologist's perspectiveAlyson L Mahar
Centre for Health Services Sciences, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
J Surg Oncol 101:195-9. 2010..To understand factors affecting optimal assessment we surveyed pathologists to identify external barriers...
A descriptive analysis of gastric cancer specimen processing techniquesAlyson L Mahar
Sunnybrook Research Institute, Toronto, Ontario, Canada
J Surg Oncol 103:248-56. 2011..A survey of pathologists in Ontario was performed to outline the processing techniques and practices for assessing gastric cancer specimens...
Improving size, lymph node metastatic rate, breast conservation, and mortality of invasive breast cancer in Rhode Island women, a well-screened populationNatalie G Coburn
Division of Surgical Oncology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
Breast Cancer Res Treat 135:831-7. 2012..3 vs. 22.6 deaths per 100,000) and 41 % comparing the period from 1990 to 2008, which may exceed the goal of 50 % mortality reduction by 2015 established by the American Cancer Society...
Surgery for gallbladder cancer: a population-based analysisNatalie G Coburn
Department of Surgery, University of Toronto, Toronto, Ontario, Canada
J Am Coll Surg 207:371-82. 2008..Single institutional studies report an aggressive surgical approach improves survival. This analysis was performed to examine the components of surgical resection and resultant survival...
A systematic review of the accuracy and indications for diagnostic laparoscopy prior to curative-intent resection of gastric cancerPierre Anthony Leake
Department of Surgery, University of Toronto, Toronto, ON, Canada
Gastric Cancer 15:S38-47. 2012..We aimed to identify and synthesize findings on the value of DL for patients with gastric cancer, in this era of improved preoperative imaging...
Compliance, attitudes and barriers to post-operative colorectal cancer follow-upJonathan Cardella
Department of Surgery, University of Toronto, Toronto, Ontario, Canada
J Eval Clin Pract 14:407-15. 2008..Our multidisciplinary team adopted a stringent CRC follow-up (FU) guideline in 2000. The purpose of this study was to assess adherence and barriers to FU for CRC...
Use of colonic stents in emergent malignant left colonic obstruction: a Markov chain Monte Carlo decision analysisAnand Govindarajan
Division of General Surgery, University of Toronto, Toronto, Ontario, Canada
Dis Colon Rectum 50:1811-24. 2007..This decision analysis examines the cost-effectiveness of colonic stenting as a bridge to surgery vs. surgery alone in the management of emergent, malignant left colonic obstruction...
Decreased breast cancer tumor size, stage, and mortality in Rhode Island: an example of a well-screened populationNatalie G Coburn
Department of Surgery, Rhode Island Hospital, Brown University School of Medicine, Providence, RI 02903, USA
Cancer Control 11:222-30. 2004..CONCLUSIONS: High mammography rates in Rhode Island are associated with smaller and earlier-stage breast cancers. This largely accounts for the decreased mortality from breast cancer and the increased rate of BCS...
Treatment considerations for gallbladder cancer should include extent of surgerySean P Cleary
J Clin Oncol 26:4521-2; author reply 4524-6. 2008
