Edward Chow

Summary

Affiliation: Sunnybrook Health Sciences Centre
Country: Canada

Publications

  1. ncbi request reprint Role of radiation therapy and radiopharmaceuticals in bone metastases
    Alysa Fairchild
    Department of Radiation Oncology, University of Alberta, Cross Cancer Institute, Edmonton, Alberta, Canada
    Curr Opin Support Palliat Care 1:169-73. 2007
  2. doi request reprint Single versus multiple fractions of repeat radiation for painful bone metastases: a randomised, controlled, non-inferiority trial
    Edward Chow
    Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, ON, Canada Electronic address
    Lancet Oncol 15:164-71. 2014
  3. doi request reprint Update of the international consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 82:1730-7. 2012
  4. doi request reprint International field testing of the reliability and validity of the EORTC QLQ-BM22 module to assess health-related quality of life in patients with bone metastases
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    Cancer 118:1457-65. 2012
  5. doi request reprint Update on the systematic review of palliative radiotherapy trials for bone metastases
    E Chow
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 24:112-24. 2012
  6. ncbi request reprint Palliative radiotherapy trials for bone metastases: a systematic review
    Edward Chow
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    J Clin Oncol 25:1423-36. 2007
  7. ncbi request reprint Symptom clusters in cancer patients with bone metastases
    Edward Chow
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 15:1035-43. 2007
  8. pmc Functional interference clusters in cancer patients with bone metastases: a secondary analysis of RTOG 9714
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 76:1507-11. 2010
  9. ncbi request reprint Mild, moderate, or severe pain categorized by patients with cancer with bone metastases
    Edward Chow
    Rapid Response Therapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Canada
    J Palliat Med 9:850-4. 2006
  10. doi request reprint Understanding the EORTC QLQ-BM22, the module for patients with bone metastases
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto ON M4N 3M5, Canada
    Expert Rev Pharmacoecon Outcomes Res 9:461-5. 2009

Detail Information

Publications118 found, 100 shown here

  1. ncbi request reprint Role of radiation therapy and radiopharmaceuticals in bone metastases
    Alysa Fairchild
    Department of Radiation Oncology, University of Alberta, Cross Cancer Institute, Edmonton, Alberta, Canada
    Curr Opin Support Palliat Care 1:169-73. 2007
    ..We review recent literature for the treatment of bone metastases and spinal cord compression, and address new developments in the prevention of adverse effects secondary to radiotherapy...
  2. doi request reprint Single versus multiple fractions of repeat radiation for painful bone metastases: a randomised, controlled, non-inferiority trial
    Edward Chow
    Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, ON, Canada Electronic address
    Lancet Oncol 15:164-71. 2014
    ..We aimed to assess two dose fractionation schedules in patients with painful bone metastases needing repeat radiation therapy...
  3. doi request reprint Update of the international consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 82:1730-7. 2012
    ....
  4. doi request reprint International field testing of the reliability and validity of the EORTC QLQ-BM22 module to assess health-related quality of life in patients with bone metastases
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    Cancer 118:1457-65. 2012
    ....
  5. doi request reprint Update on the systematic review of palliative radiotherapy trials for bone metastases
    E Chow
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 24:112-24. 2012
    ..To update previous meta-analyses of randomised palliative radiotherapy trials comparing single fractions versus multiple fractions...
  6. ncbi request reprint Palliative radiotherapy trials for bone metastases: a systematic review
    Edward Chow
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    J Clin Oncol 25:1423-36. 2007
    ..The objective is to update previous meta-analyses with a systematic review of randomized palliative radiotherapy (RT) trials comparing single fractions (SFs) versus multiple fractions (MFs)...
  7. ncbi request reprint Symptom clusters in cancer patients with bone metastases
    Edward Chow
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 15:1035-43. 2007
    ..The purpose of this study is to explore whether bone pain "clusters" with other symptoms in patients with bone metastases...
  8. pmc Functional interference clusters in cancer patients with bone metastases: a secondary analysis of RTOG 9714
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 76:1507-11. 2010
    ..To explore the relationships (clusters) among the functional interference items in the Brief Pain Inventory (BPI) in patients with bone metastases...
  9. ncbi request reprint Mild, moderate, or severe pain categorized by patients with cancer with bone metastases
    Edward Chow
    Rapid Response Therapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Canada
    J Palliat Med 9:850-4. 2006
    ..To examine how patients categorize their pain with the two commonly employed scales...
  10. doi request reprint Understanding the EORTC QLQ-BM22, the module for patients with bone metastases
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto ON M4N 3M5, Canada
    Expert Rev Pharmacoecon Outcomes Res 9:461-5. 2009
    ..Bone metastases clinical trial QoL outcomes will be compared across trials through the utilization of a consistent and valid module questionnaire...
  11. ncbi request reprint Symptom clusters in cancer patients with brain metastases
    E Chow
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 20:76-82. 2008
    ..To explore the presence of symptom clusters in patients with brain metastases...
  12. doi request reprint Would larger radiation fields lead to a faster onset of pain relief in the palliation of bone metastases?
    Edward Chow
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada
    Int J Radiat Oncol Biol Phys 74:1563-6. 2009
    ..The primary objective of this study is to examine whether there is a relationship between the areas of radiation treatment and onset of pain relief...
  13. doi request reprint Recursive partitioning analysis of prognostic factors for survival in patients with advanced cancer
    Edward Chow
    Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 73:1169-76. 2009
    ..To construct a predictive model for survival of patients referred to the Rapid Response Radiotherapy Program using recursive partitioning (RP)...
  14. doi request reprint Update on radiation treatment for cancer pain
    Edward Chow
    Department of Radiation Oncology, University of Toronto, Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada
    Curr Opin Support Palliat Care 1:11-5. 2007
    ..This review addresses the latest advances in radiation treatment for cancer pain...
  15. ncbi request reprint Dexamethasone for the prophylaxis of radiation-induced pain flare after palliative radiotherapy for bone metastases: a pilot study
    Edward Chow
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Center, University of Toronto, Toronto, Canada
    Support Care Cancer 15:643-7. 2007
    ..To investigate the efficacy of dexamethasone as a prophylactic adjuvant analgesic to decrease pain flare and to assess its safety and tolerance of dexamethasone...
  16. doi request reprint Predictive model for survival in patients with advanced cancer
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
    J Clin Oncol 26:5863-9. 2008
    ..To derive and validate a simple predictive model for survival of patients with metastatic cancer attending a palliative radiotherapy clinic...
  17. doi request reprint The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire for patients with bone metastases: the EORTC QLQ-BM22
    Edward Chow
    Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N3M5, Canada
    Eur J Cancer 45:1146-52. 2009
    ..The aim of this study was to develop a bone metastases module to supplement the European Organisation for Research and Treatment of Cancer Core Questionnaire (EORTC QLQ-C30) or the EORTC QLQ-C15-PAL for patients with bone metastases...
  18. doi request reprint Comparing baseline symptom severity and demographics over two time periods in an outpatient palliative radiotherapy clinic
    Luluel Khan
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 20:549-55. 2012
    ..The secondary objective was to assess any changes in the baseline demographics of these patients...
  19. doi request reprint Determining the incidence of pain flare following palliative radiotherapy for symptomatic bone metastases: results from three canadian cancer centers
    Amanda Hird
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 75:193-7. 2009
    ..To determine the incidence of pain flare following radiotherapy (RT) for painful bone metastases...
  20. doi request reprint Fatigue in advanced cancer patients attending an outpatient palliative radiotherapy clinic as screened by the Edmonton Symptom Assessment System
    Liang Zeng
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 20:1037-42. 2012
    ..The purpose of this study was to report the presence, severity, and correlating factors of fatigue in advanced cancer patients attending an outpatient palliative radiotherapy clinic...
  21. doi request reprint Minimal clinically important differences in the Edmonton symptom assessment system in patients with advanced cancer
    Gillian Bedard
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Pain Symptom Manage 46:192-200. 2013
    ..Longitudinal symptom monitoring is important in the setting of patients with advanced cancer. Scores over time may naturally fluctuate, although a patient may feel the same...
  22. doi request reprint Symptom clusters in patients with advanced cancer: a reanalysis comparing different statistical methods
    Emily Chen
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Pain Symptom Manage 44:23-32. 2012
    ..The clinical relevance of symptom cluster research remains questionable if inconsistencies, partially attributable to the varying statistical analyses used, exist...
  23. ncbi request reprint Percutaneous vertebroplasty in patients with intractable pain from osteoporotic or metastatic fractures: A prospective study using quality-of-life assessment
    Gordon Cheung
    Bone Metastases Clinic, Toronto Sunnybrook Regional Cancer Centre, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, ON
    Can Assoc Radiol J 57:13-21. 2006
    ..We prospectively evaluate the efficacy of PVP in the relief of pain and improvement in quality of life of patients with intractable pain from osteoporotic and metastatic fractures...
  24. doi request reprint Projected referral to other healthcare services in an outpatient palliative radiotherapy clinic
    Janet Nguyen
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, University of Toronto, Toronto, ON, M4N 3M5, Canada
    Expert Rev Pharmacoecon Outcomes Res 12:237-43. 2012
    ..To investigate the projected referral to other healthcare services in an outpatient palliative radiotherapy clinic...
  25. doi request reprint Patients' and health care professionals' evaluation of health-related quality of life issues in bone metastases
    Kristin Harris
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Eur J Cancer 45:2510-8. 2009
    ..This information has been an important component in the development of a health-related quality of life questionnaire for patients with bone metastases (EORTC QLQ-BM 22)...
  26. doi request reprint Symptom clusters in patients with bone metastases--a reanalysis comparing different statistical methods
    Emily Chen
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 20:2811-20. 2012
    ....
  27. doi request reprint EORTC QLQ-C15-PAL quality of life scores in patients with advanced cancer referred for palliative radiotherapy
    Amanda Caissie
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 20:841-8. 2012
    ....
  28. doi request reprint Comparison of pain response and functional interference outcomes between spinal and non-spinal bone metastases treated with palliative radiotherapy
    Liang Zeng
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada
    Support Care Cancer 20:633-9. 2012
    ....
  29. doi request reprint Physician expectations of treatment outcomes for patients with brain metastases referred for whole brain radiotherapy
    Elizabeth A Barnes
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 76:187-92. 2010
    ..The secondary objectives were to determine the factors influencing the expectations and to examine the accuracy of the physician-estimated patient survival...
  30. doi request reprint An international prospective study establishing minimal clinically important differences in the EORTC QLQ-BM22 and QLQ-C30 in cancer patients with bone metastases
    Liang Zeng
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, Canada M4N 3M5
    Support Care Cancer 20:3307-13. 2012
    ..The purpose of this study was to establish the minimal clinically important difference (MCID) for the European Organisation for Research and Treatment of Cancer (EORTC) bone metastases module (EORTC QLQ-BM22)...
  31. doi request reprint Validation of a predictive model for survival in metastatic cancer patients attending an outpatient palliative radiotherapy clinic
    Edward Chow
    Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 73:280-7. 2009
    ..To validate a predictive model for survival of patients attending a palliative radiotherapy clinic...
  32. ncbi request reprint Quality of life in patients with brain metastases treated with a palliative course of whole-brain radiotherapy
    Megan Doyle
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada
    J Palliat Med 10:367-74. 2007
    ..The secondary objective was to assess the level of agreement between patient and proxy quality of life scores...
  33. doi request reprint Retrospective assessment of cancer pain management in an outpatient palliative radiotherapy clinic using the Pain Management Index
    Gunita Mitera
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada M4N 3M5
    J Pain Symptom Manage 39:259-67. 2010
    ....
  34. doi request reprint Rapid improvement in pain and functional level in a patient with metastatic renal cell carcinoma: a case report and review of the literature
    Amanda E Hird
    Rapid Response Radiotherapy Program, Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    J Palliat Med 11:1156-61. 2008
    ..Concurrently, quality of life and performance status improved dramatically. Although we are unsure of the exact mechanism for such rapid improvement in metastatic bone lesions, the swiftness this improvement deserves reporting...
  35. doi request reprint Prophylaxis of radiotherapy-induced nausea and vomiting in the palliative treatment of bone metastases
    Kristopher Dennis
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 20:1673-8. 2012
    ..To document the incidence and timing of radiotherapy-induced nausea and vomiting (RINV) in the treatment of bone metastases among patients receiving prophylaxis with a 5-HT(3) receptor antagonist...
  36. doi request reprint International patterns of practice in palliative radiotherapy for painful bone metastases: evidence-based practice?
    Alysa Fairchild
    Department of Radiation Oncology, Cross Cancer Institute, Edmonton, AB, Canada
    Int J Radiat Oncol Biol Phys 75:1501-10. 2009
    ..However, according to previous surveys, SF schedules remain underused. The objectives of this study were to determine the current patterns of practice internationally and to investigate the factors influencing this practice...
  37. doi request reprint The palliative performance scale: examining its inter-rater reliability in an outpatient palliative radiation oncology clinic
    Sarah Campos
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Center, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada
    Support Care Cancer 17:685-90. 2009
    ..Currently, it is being used to measure palliative patient performance status in a variety of settings. Despite its widespread use, only one study has examined the inter-rater reliability of the PPS...
  38. doi request reprint Symptoms and quality of life in cancer patients with brain metastases following palliative radiotherapy
    Jennifer Wong
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Canada
    Int J Radiat Oncol Biol Phys 75:1125-31. 2009
    ..To examine prospectively patient self-rated symptoms and quality of life (QOL) indicators in patients with brain metastases following whole brain radiotherapy (WBRT)...
  39. doi request reprint Continued success of the rapid response radiotherapy program: a review of 2004-2008
    Eric de Sa
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada
    Support Care Cancer 17:757-62. 2009
    ..To update the clinical activity of the Rapid Response Radiotherapy Program (RRRP)...
  40. doi request reprint Is response to radiotherapy in patients related to the severity of pretreatment pain?
    Andrea Kirou-Mauro
    Department of Radiation Oncology, Odette Cancer Center, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 71:1208-12. 2008
    ..The primary objective of this study was to determine whether there is a relationship between the severity of pretreatment pain and response to palliative radiotherapy (RT) for painful bone metastases...
  41. doi request reprint Elderly patients with painful bone metastases should be offered palliative radiotherapy
    Sarah Campos
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 76:1500-6. 2010
    ..To investigate the efficacy of palliative radiotherapy (RT) in relieving metastatic bone pain in elderly patients...
  42. doi request reprint Has pain management in cancer patients with bone metastases improved? A seven-year review at an outpatient palliative radiotherapy clinic
    Andrea M Kirou-Mauro
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Pain Symptom Manage 37:77-84. 2009
    ....
  43. doi request reprint Correlation of computed tomography imaging features with pain response in patients with spine metastases after radiation therapy
    Gunita Mitera
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada M4N 3M5
    Int J Radiat Oncol Biol Phys 81:827-30. 2011
    ..To correlate computed tomography (CT) imaging features of spinal metastases with pain relief after radiotherapy (RT)...
  44. doi request reprint Pain flare is a common adverse event in steroid-naïve patients after spine stereotactic body radiation therapy: a prospective clinical trial
    Andrew Chiang
    Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 86:638-42. 2013
    ..To determine the incidence of pain flare after spine stereotactic body radiation therapy (SBRT) in steroid-naïve patients and identify predictive factors...
  45. doi request reprint Symptom clusters using the Spitzer quality of life index in patients with brain metastases--a reanalysis comparing different statistical methods
    Luluel Khan
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 21:467-73. 2013
    ..The purpose of this paper is to determine whether the use of three different statistical methods influences the composition of symptom clusters derived from patients with brain metastases...
  46. doi request reprint Symptom clusters in patients with advanced cancer: sub-analysis of patients reporting exclusively non-zero ESAS scores
    Emily Chen
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Palliat Med 26:826-33. 2012
    ..Varying statistical methods may also contribute to inconsistencies of cluster results...
  47. doi request reprint Quality of life after palliative radiation therapy for patients with painful bone metastases: results of an international study validating the EORTC QLQ-BM22
    Liang Zeng
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 84:e337-42. 2012
    ..The purpose of our study was to compare bone metastasis-specific QOL scores among patients who responded differently to palliative RT...
  48. doi request reprint Do elderly patients with metastatic cancer have worse quality of life scores?
    Kaitlin Koo
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 20:2121-7. 2012
    ..The purpose of this study is to compare self-reported quality of life (QOL) scores in old and young patients with metastatic cancer using the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C15-PAL questionnaire...
  49. doi request reprint International patterns of practice in the management of radiation therapy-induced nausea and vomiting
    Kristopher Dennis
    Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 84:e49-60. 2012
    ..To investigate international patterns of practice in the management of radiation therapy-induced nausea and vomiting (RINV)...
  50. doi request reprint FACT-Br for assessment of quality of life in patients receiving treatment for brain metastases: a literature review
    Karen Lien
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada
    Expert Rev Pharmacoecon Outcomes Res 11:701-8. 2011
    ..We aim to provide a comprehensive review to examine the use of the FACT-Br as a QoL assessment for patients with brain metastases...
  51. doi request reprint Subgroups of advanced cancer patients clustered by their symptom profiles: quality-of-life outcomes
    Amna Husain
    Temmy Latner Centre for Palliative Care, Mount Sinai Hospital, Toronto, Ontario, Canada
    J Palliat Med 14:1246-53. 2011
    ..This study clustered patients by their symptom profiles to identify subgroups that may be at higher risk for poor quality of life (QOL) and that may, therefore, benefit most from targeted interventions...
  52. doi request reprint Symptom clusters in patients with cancer with metastatic bone pain
    Stephanie Hadi
    Department of Radiation Oncology, Odette Cancer Centre, Toronto, Ontario, Canada
    J Palliat Med 11:591-600. 2008
    ..Secondary objectives were to determine whether symptom clusters change with palliative radiotherapy (RT) and to compare the difference between responders and nonresponders to radiation...
  53. doi request reprint Rare bone metastases of the olecranon
    Shaelyn Culleton
    Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Palliat Med 11:1088-91. 2008
    ..The incidence of olecranon metastasis is extremely rare in all cancers and so far only two cases have been reported in literature. We report the third case of an olecranon metastasis in a patient with renal cell carcinoma...
  54. ncbi request reprint Involvement of family physicians in the care of cancer patients seen in the palliative Rapid Response Radiotherapy Program
    Elizabeth A Barnes
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, 2075 Bayview Ave, Toronto, Ontario, Canada, M4N 3M5
    J Clin Oncol 25:5758-62. 2007
    ..Secondary objectives were to identify factors predicting for perceived FP involvement in patient cancer care...
  55. doi request reprint Predictive factors of overall well-being using the EORTC QLQ-C15-PAL extracted from the EORTC QLQ-C30
    Kinsey Lam
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Palliat Med 16:402-8. 2013
    ..The purpose of this study was to compare predictive factors for well-being in the QLQ-C15-PAL extracted from the EORTC Quality of Life Questionnaire - Core 30 (QLQ-C30) with the QLQ-C30 itself...
  56. doi request reprint Quality of life in patients with brain metastases using the EORTC QLQ-BN20+2 and QLQ-C15-PAL
    Amanda Caissie
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 83:1238-45. 2012
    ....
  57. doi request reprint The EORTC QLQ-BN20 for assessment of quality of life in patients receiving treatment or prophylaxis for brain metastases: a literature review
    Andrew Leung
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Expert Rev Pharmacoecon Outcomes Res 11:693-700. 2011
    ..The European Organization for Research and Treatment of Cancer (EORTC) QLQ-BN20 is a QoL assessment specific to brain neoplasms. We aim to provide a review of the current use of the EORTC QLQ-BN20 for patients with brain metastases...
  58. ncbi request reprint Prospective assessment of patient-rated symptoms following whole brain radiotherapy for brain metastases
    Edward Chow
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Center, University of Toronto, Toronto, Ontario, Canada
    J Pain Symptom Manage 30:18-23. 2005
    ..0 to 1.8; drowsiness 1.2 to 1.8; and appetite 2.2 to 2.4. The data demonstrate that certain parameters of quality of life worsen after whole brain radiotherapy...
  59. ncbi request reprint Accuracy of survival prediction by palliative radiation oncologists
    Edward Chow
    Division of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Int J Radiat Oncol Biol Phys 61:870-3. 2005
    ..To examine the accuracy of survival prediction by palliative radiation oncologists...
  60. doi request reprint Preliminary results of the generation of a shortened quality-of-life assessment for patients with advanced cancer: the FACIT-Pal-14
    Liang Zeng
    Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Palliat Med 16:509-15. 2013
    ..The purpose of this study was to identify the most important items of the Functional Assessment of Chronic Illness Therapy-Palliative Care (FACIT-Pal) to create an abbreviated questionnaire for future palliative care trials...
  61. doi request reprint Symptom clusters in patients with metastatic cancer: a literature review
    Nemica Thavarajah
    Department of Radiation Oncology, Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Expert Rev Pharmacoecon Outcomes Res 12:597-604. 2012
    ..Further exploration in metastatic symptom cluster research will ideally improve patient outcomes by facilitating improved symptom management in future clinical practice...
  62. doi request reprint A literature review of symptom clusters in patients with breast cancer
    Janet Nguyen
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Expert Rev Pharmacoecon Outcomes Res 11:533-9. 2011
    ....
  63. doi request reprint A multicenter assessment of the adequacy of cancer pain treatment using the pain management index
    Gunita Mitera
    Department of Radiation Therapy, Odette Cancer Center, University of Toronto, Toronto, Ontario, Canada
    J Palliat Med 13:589-93. 2010
    ....
  64. doi request reprint Exploration of symptoms clusters within cancer patients with brain metastases using the Spitzer Quality of Life Index
    Amanda Hird
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada
    Support Care Cancer 18:335-42. 2010
    ..The objective of this study was to explore the presence of symptom clusters in patients with brain metastases treated with whole brain radiotherapy (WBRT)...
  65. ncbi request reprint Treatment of bone metastases with palliative radiotherapy: patients' treatment preferences
    Ewa Szumacher
    Rapid Response Radiotherapy Program, Bone Metastases Site Group, Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 61:1473-81. 2005
    ..800 cGy in one fraction) for painful bone metastases...
  66. ncbi request reprint Computed tomography (CT) evaluation of breast cancer patients with osteolytic bone metastases undergoing palliative radiotherapy--a feasibility study
    Edward Chow
    Rapid Response Radiotherapy Program and Bone Metastases Site Group, Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
    Radiother Oncol 70:291-4. 2004
    ..The median % density change following single 8Gy, 20Gy/5#, 30Gy/10# were: 128 (range 98-255), 141 (79-342), and 145 (65-235), respectively. It is feasible to evaluate remineralization of osteolytic lesions with palliative radiotherapy...
  67. doi request reprint Comparing prognostic factors in patients with spinal metastases: a literature review
    Marko Popovic
    Department of Radiation Oncology, Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Expert Rev Pharmacoecon Outcomes Res 12:345-56. 2012
    ..For future studies, the authors encourage the development of models capable of inclusion of all patients with spinal metastases...
  68. doi request reprint Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases
    May N Tsao
    Department ofRadiationOncology, OdetteCancerCentre, Toronto, Canada
    Cochrane Database Syst Rev 4:CD003869. 2012
    ..Brain radiotherapy is used to treat cancer participants who have brain metastases from various primary malignancies.This is an update to the original review published in Issue 3, 2006...
  69. ncbi request reprint Communication with referring physicians in a palliative radiotherapy clinic
    Elizabeth A Barnes
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, M4 N 3M5, Canada
    Support Care Cancer 12:669-73. 2004
    ..The purpose of this study was to assess how useful referring physicians perceive this interim report and whether this report needs to be modified to meet their information needs...
  70. doi request reprint Evaluating correlation and interrater reliability for four performance scales in the palliative care setting
    Jeff Myers
    Palliative Care Consult Team, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5, Canada
    J Pain Symptom Manage 39:250-8. 2010
    ..In addition, given that low levels of exact rater agreement could have substantial clinical implications for patients, we suggest that this parameter be considered in the design of future comparative studies...
  71. doi request reprint The role of plain radiographs in management of bone metastases
    Nadia Salvo
    Department of Radiation Oncology, Sunnybrook Odette Cancer Centre, Toronto, Ontario, Canada
    J Palliat Med 12:195-8. 2009
    ..However, plain x-rays can also lead to rare false-positive results. We present a case with a false-positive result in a patient with lung cancer...
  72. ncbi request reprint Multidisciplinary radiation oncology palliative care rounds as a continuing educational activity implementing the rapid response radiotherapy program at the toronto sunnybrook regional cancer centre
    Ewa Szumacher
    Department of Radiation Oncology, University of Toronto, Ontario, Canada
    J Cancer Educ 18:86-90. 2003
    ....
  73. doi request reprint Edmonton symptom assessment scale as a prognosticative indicator in patients with advanced cancer
    Liang Zeng
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Canada
    J Palliat Med 14:337-42. 2011
    ..Few studies incorporate patient self-assessment scales in prognostic models of survival prediction. The Edmonton Symptom Assessment Scale (ESAS) is commonly used as a symptom screening tool in cancer patients...
  74. doi request reprint Self-reported rates of sleep disturbance in patients with symptomatic bone metastases attending an outpatient radiotherapy clinic
    Luluel Khan
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    J Palliat Med 14:708-14. 2011
    ..To examine the reported rates and predictive factors for sleep disturbance in patients with bone metastases...
  75. doi request reprint Prophylaxis of radiation-induced nausea and vomiting using 5-hydroxytryptamine-3 serotonin receptor antagonists: a systematic review of randomized trials
    Nadia Salvo
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Int J Radiat Oncol Biol Phys 82:408-17. 2012
    ..To systematically review the effectiveness and safety of 5-hydroxytryptamine-3 receptor antagonists (5-HT3 RAs) compared with other antiemetic medication or placebo for prophylaxis of radiation-induced nausea and vomiting...
  76. ncbi request reprint Pain flare following external beam radiotherapy and meaningful change in pain scores in the treatment of bone metastases
    Edward Chow
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, Ont M4N 3M5, Canada
    Radiother Oncol 75:64-9. 2005
    ..To examine the incidence of pain flare following external beam radiotherapy and to determine what constitutes a meaningful change in pain scores in the treatment of bone metastases...
  77. doi request reprint Comparison of the EORTC QLQ-BM22 and the FACT-BP for assessment of quality of life in cancer patients with bone metastases
    Marko Popovic
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, M4N 3M5, ON, Canada
    Expert Rev Pharmacoecon Outcomes Res 12:213-9. 2012
    ..The purpose of this study was to compare the development and characteristics of these two tools, as well as their current use in palliative research...
  78. ncbi request reprint International consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases
    Edward Chow
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Ontario, Canada
    Radiother Oncol 64:275-80. 2002
    ..To reach a consensus on a set of optimal endpoint measurements for future external beam radiotherapy trials in bone metastases...
  79. doi request reprint Comparison of the EORTC QLQ-C15-PAL and the FACIT-Pal for assessment of quality of life in patients with advanced cancer
    Karen Lien
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Expert Rev Pharmacoecon Outcomes Res 11:541-7. 2011
    ..Future studies should directly compare these two tools and validate their use through a number of administration modes...
  80. ncbi request reprint Successful salvage using percutaneous vertebroplasty in cancer patients with painful spinal metastases or osteoporotic compression fractures
    Edward Chow
    Bone Metastases Clinic, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Ontario, Canada M4N 3M5
    Radiother Oncol 70:265-7. 2004
    ..Percutaneous vertebroplasty significantly improved pain, mobility and quality of life in cancer patients with bone metastases who failed radiation or with osteoporotic compression fractures. The serious complication is relatively rare...
  81. ncbi request reprint Patient expectation of the partial response and response shift in pain score
    Edward Chow
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Canada
    Support Cancer Ther 4:110-8. 2007
    ..This might become the definition of partial response in future trials. Response shift was observed in this group of patients but in opposing directions and without affecting the overall outcome...
  82. doi request reprint The not-so-crystal ball: the ongoing challenge of physician prognostication
    Sarah Campos
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    J Psychosom Res 65:67-9. 2008
  83. ncbi request reprint Radiotherapeutic management of brain metastases: a systematic review and meta-analysis
    May N Tsao
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, 2075 Bayview Avenue, Toronto, Ont, Canada M4N 3M5
    Cancer Treat Rev 31:256-73. 2005
    ..The management of brain metastases is a significant health care problem. An estimated 20-40% of cancer patients will develop metastatic cancer to the brain during the course of their illness...
  84. doi request reprint Immediate pain relief and improved structural stability after percutaneous vertebroplasty for a severely destructive vertebral compression fracture
    Jennifer Wong
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Toronto, Ontario, Canada
    J Palliat Med 12:97-100. 2009
    ..Percutaneous vertebroplasty provided immediate pain relief and restored structural stability of the diseased vertebra...
  85. ncbi request reprint What should be the optimal cut points for mild, moderate, and severe pain?
    Kathy K Li
    Department of Radiation Oncology, Odette Cancer Centre, Toronto, Ontario, Canada
    J Palliat Med 10:1338-46. 2007
    ..Thus, the purpose of the current study was to identify optimal cut points (CP) of the three pain severity categories for worst, average, and current pain...
  86. doi request reprint Clinical benefit of reirradiation: a case report
    Candi J Flynn
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada
    J Palliat Med 11:112-6. 2008
  87. ncbi request reprint A phase II trial of palliative radiotherapy for metastatic renal cell carcinoma
    Justin Lee
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Cancer 104:1894-900. 2005
    ..The authors conducted a prospective study to assess the effect of RT on symptoms and quality of life (QOL) in patients with metastatic RCC...
  88. ncbi request reprint Symptom control and palliative care content of abstracts presented at the Canadian Association of Radiation Oncologists annual meetings
    Elizabeth A Barnes
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, 2075 Bayview Avenue, Toronto, Ontario, M4 N 3M5, Canada
    Support Care Cancer 12:91-4. 2004
    ..The purpose of this study was to determine the number of abstracts relating to SCPC presented at the annual Canadian Association of Radiation Oncologists (CARO) meetings, and whether this number has increased over time...
  89. ncbi request reprint A predictive model for survival in metastatic cancer patients attending an outpatient palliative radiotherapy clinic
    Edward Chow
    Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Canada
    Int J Radiat Oncol Biol Phys 53:1291-302. 2002
    ..To develop a predictive model for survival from the time of presentation in an outpatient palliative radiotherapy clinic...
  90. ncbi request reprint Review of telephone follow-up experience at the Rapid Response Radiotherapy Program
    Edward Chow
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Support Care Cancer 13:549-53. 2005
    ..To review the feasibility of telephone follow-up following a 3-year experience from 1999 to 2001 at the Rapid Response Radiotherapy Program as a prospective radiotherapy outcome assessment of symptom palliation...
  91. ncbi request reprint Radiotherapeutic approaches to metastatic disease
    Edward Chow
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, 2075 Bayview Avenue, ON M4 N 3M5, Toronto, Canada
    World J Urol 21:229-42. 2003
    ..This article focuses on the management of bone pain and its complications (pathological fractures and spinal cord compression) with radiation treatment...
  92. ncbi request reprint Successful validation of a survival prediction model in patients with metastases in the spinal column
    Edward Chow
    Department of Radiation Oncology, Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 65:1522-7. 2006
    ..The objective of this study was to validate the Dutch model and compare with our previously developed survival model at the Rapid Response Radiotherapy Program (RRRP model)...
  93. ncbi request reprint Do physicians follow systemic treatment and funding policy guidelines?
    Mark Clemons
    Toronto Sunnybrook Regional Cancer Centre, Canada
    Can J Clin Pharmacol 11:e168-78. 2004
    ..In addition we assessed whether or not physicians at these centres are following their local treatment guidelines and funding policies...
  94. ncbi request reprint Utilization of palliative radiotherapy for breast cancer patients with bone metastases treated with bisphosphonates-Toronto Sunnybrook Regional Cancer Centre experience
    Katherine Enright
    University of Western Ontario, London, Ontario, Canada
    Support Care Cancer 12:48-52. 2004
    ..We undertook an evaluation of palliative radiotherapy utilization rates in breast cancer patients who received bisphosphonates for the treatment of bone metastases in a major Canadian cancer center...
  95. doi request reprint A single set of numerical cutpoints to define moderate and severe symptoms for the Edmonton Symptom Assessment System
    Debbie Selby
    Palliative Care Department, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario M4N 3M5, Canada
    J Pain Symptom Manage 39:241-9. 2010
    ..Across all ESAS symptoms, then, 7 or higher represents a severe symptom by patient definition, whereas a cutpoint of either 4 or 5 could reasonably define combined moderate and severe symptoms...
  96. ncbi request reprint Primary treatment endpoint following palliative radiotherapy for painful bone metastases: need for a consensus definition?
    Jackson S Y Wu
    Department of Radiation Oncology, Hamilton Regional Cancer Centre, McMaster University, Ontario, Canada
    Clin Oncol (R Coll Radiol) 14:70-7. 2002
    ....
  97. ncbi request reprint Does psychosocial intervention improve survival in cancer? A meta-analysis
    Edward Chow
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    Palliat Med 18:25-31. 2004
    ..A systematic review of randomized trials that have examined the effectiveness of psychosocial intervention in cancer patients in terms of survival prolongation was conducted...
  98. ncbi request reprint Symptom distress in patients attending an outpatient palliative radiotherapy clinic
    Nicole Bradley
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Center, University of Toronto, Toronto, Ontario, Canada
    J Pain Symptom Manage 30:123-31. 2005
    ..Symptom assessment tools, such as the ESAS, allow for the identification of symptoms and their severity. The appropriate regimen for management of pain and symptoms in metastatic cancer patients can then be planned...
  99. pmc Radiation treatment for breast cancer. Recent advances
    Edward Chow
    Toronto Sunnybrook Regional Cancer Centre, Department of Radiation Oncology, 2075 Bayview Ave, Toronto, ON M4N 3N5
    Can Fam Physician 48:1065-9. 2002
    ..To review recent advances in radiation therapy in treatment of breast cancer...
  100. ncbi request reprint Comparison of the efficacy and acute toxicity of weekly versus daily chemoradiotherapy for non-small-cell lung cancer: a meta-analysis
    Eileen Rakovitch
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 58:196-203. 2004
    ..It remains unknown whether a difference in efficacy or toxicity exists between these approaches. A systematic review was performed to compare the efficacy and toxicity of weekly vs. daily ChRT...
  101. doi request reprint Change in urinary markers of osteoclast activity following palliative radiotherapy for bone metastases
    E Chow
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 21:336-42. 2009
    ..To examine the effect of radiotherapy for bone metastases on urinary markers of osteoclast activity...