Edward Chow

Summary

Affiliation: Sunnybrook Health Sciences Centre
Country: Canada

Publications

  1. ncbi Review of patterns of practice and patients' preferences in the treatment of bone metastases with palliative radiotherapy
    Nicole M E Bradley
    Department of Health Studies and Gerontology, Faculty of Applied Health Sciences, University of Waterloo, Waterloo, Canada
    Support Care Cancer 15:373-85. 2007
  2. ncbi Role of radiation therapy and radiopharmaceuticals in bone metastases
    Alysa Fairchild
    Department of Radiation Oncology, University of Alberta, Cross Cancer Institute, Edmonton, Alberta, Canada
    Curr Opin Support Palliat Care 1:169-73. 2007
  3. ncbi Update of the international consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 82:1730-7. 2012
  4. ncbi International field testing of the reliability and validity of the EORTC QLQ-BM22 module to assess health-related quality of life in patients with bone metastases
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    Cancer 118:1457-65. 2012
  5. ncbi Update on the systematic review of palliative radiotherapy trials for bone metastases
    E Chow
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 24:112-24. 2012
  6. ncbi Dexamethasone for the prophylaxis of radiation-induced pain flare after palliative radiotherapy for bone metastases: a pilot study
    Edward Chow
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Center, University of Toronto, Toronto, Canada
    Support Care Cancer 15:643-7. 2007
  7. ncbi Functional interference clusters in cancer patients with bone metastases: a secondary analysis of RTOG 9714
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 76:1507-11. 2010
  8. ncbi Update on radiation treatment for cancer pain
    Edward Chow
    Department of Radiation Oncology, University of Toronto, Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada
    Curr Opin Support Palliat Care 1:11-5. 2007
  9. ncbi Understanding the EORTC QLQ-BM22, the module for patients with bone metastases
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto ON M4N 3M5, Canada
    Expert Rev Pharmacoecon Outcomes Res 9:461-5. 2009
  10. ncbi Symptom clusters in cancer patients with brain metastases
    E Chow
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 20:76-82. 2008

Detail Information

Publications112 found, 100 shown here

  1. ncbi Review of patterns of practice and patients' preferences in the treatment of bone metastases with palliative radiotherapy
    Nicole M E Bradley
    Department of Health Studies and Gerontology, Faculty of Applied Health Sciences, University of Waterloo, Waterloo, Canada
    Support Care Cancer 15:373-85. 2007
    ..Since the 1980s, randomized clinical trials showed that single fraction radiotherapy (RT) provided equal pain relief as multiple fractions of RT in the treatment of bone metastases...
  2. ncbi Role of radiation therapy and radiopharmaceuticals in bone metastases
    Alysa Fairchild
    Department of Radiation Oncology, University of Alberta, Cross Cancer Institute, Edmonton, Alberta, Canada
    Curr Opin Support Palliat Care 1:169-73. 2007
    ..We review recent literature for the treatment of bone metastases and spinal cord compression, and address new developments in the prevention of adverse effects secondary to radiotherapy...
  3. ncbi Update of the international consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 82:1730-7. 2012
    ....
  4. ncbi International field testing of the reliability and validity of the EORTC QLQ-BM22 module to assess health-related quality of life in patients with bone metastases
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    Cancer 118:1457-65. 2012
    ....
  5. ncbi Update on the systematic review of palliative radiotherapy trials for bone metastases
    E Chow
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 24:112-24. 2012
    ..To update previous meta-analyses of randomised palliative radiotherapy trials comparing single fractions versus multiple fractions...
  6. ncbi Dexamethasone for the prophylaxis of radiation-induced pain flare after palliative radiotherapy for bone metastases: a pilot study
    Edward Chow
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Center, University of Toronto, Toronto, Canada
    Support Care Cancer 15:643-7. 2007
    ..To investigate the efficacy of dexamethasone as a prophylactic adjuvant analgesic to decrease pain flare and to assess its safety and tolerance of dexamethasone...
  7. ncbi Functional interference clusters in cancer patients with bone metastases: a secondary analysis of RTOG 9714
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 76:1507-11. 2010
    ..To explore the relationships (clusters) among the functional interference items in the Brief Pain Inventory (BPI) in patients with bone metastases...
  8. ncbi Update on radiation treatment for cancer pain
    Edward Chow
    Department of Radiation Oncology, University of Toronto, Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada
    Curr Opin Support Palliat Care 1:11-5. 2007
    ..This review addresses the latest advances in radiation treatment for cancer pain...
  9. ncbi Understanding the EORTC QLQ-BM22, the module for patients with bone metastases
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto ON M4N 3M5, Canada
    Expert Rev Pharmacoecon Outcomes Res 9:461-5. 2009
    ..Bone metastases clinical trial QoL outcomes will be compared across trials through the utilization of a consistent and valid module questionnaire...
  10. ncbi Symptom clusters in cancer patients with brain metastases
    E Chow
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 20:76-82. 2008
    ..To explore the presence of symptom clusters in patients with brain metastases...
  11. ncbi Palliative radiotherapy trials for bone metastases: a systematic review
    Edward Chow
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    J Clin Oncol 25:1423-36. 2007
    ..The objective is to update previous meta-analyses with a systematic review of randomized palliative radiotherapy (RT) trials comparing single fractions (SFs) versus multiple fractions (MFs)...
  12. ncbi Symptom clusters in cancer patients with bone metastases
    Edward Chow
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 15:1035-43. 2007
    ..The purpose of this study is to explore whether bone pain "clusters" with other symptoms in patients with bone metastases...
  13. ncbi Mild, moderate, or severe pain categorized by patients with cancer with bone metastases
    Edward Chow
    Rapid Response Therapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Canada
    J Palliat Med 9:850-4. 2006
    ..To examine how patients categorize their pain with the two commonly employed scales...
  14. ncbi Recursive partitioning analysis of prognostic factors for survival in patients with advanced cancer
    Edward Chow
    Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 73:1169-76. 2009
    ..To construct a predictive model for survival of patients referred to the Rapid Response Radiotherapy Program using recursive partitioning (RP)...
  15. ncbi Predictive model for survival in patients with advanced cancer
    Edward Chow
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
    J Clin Oncol 26:5863-9. 2008
    ..To derive and validate a simple predictive model for survival of patients with metastatic cancer attending a palliative radiotherapy clinic...
  16. ncbi Would larger radiation fields lead to a faster onset of pain relief in the palliation of bone metastases?
    Edward Chow
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada
    Int J Radiat Oncol Biol Phys 74:1563-6. 2009
    ..The primary objective of this study is to examine whether there is a relationship between the areas of radiation treatment and onset of pain relief...
  17. ncbi The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire for patients with bone metastases: the EORTC QLQ-BM22
    Edward Chow
    Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N3M5, Canada
    Eur J Cancer 45:1146-52. 2009
    ..The aim of this study was to develop a bone metastases module to supplement the European Organisation for Research and Treatment of Cancer Core Questionnaire (EORTC QLQ-C30) or the EORTC QLQ-C15-PAL for patients with bone metastases...
  18. ncbi Comparing baseline symptom severity and demographics over two time periods in an outpatient palliative radiotherapy clinic
    Luluel Khan
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 20:549-55. 2012
    ..The secondary objective was to assess any changes in the baseline demographics of these patients...
  19. ncbi Determining the incidence of pain flare following palliative radiotherapy for symptomatic bone metastases: results from three canadian cancer centers
    Amanda Hird
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 75:193-7. 2009
    ..To determine the incidence of pain flare following radiotherapy (RT) for painful bone metastases...
  20. ncbi Symptom clusters in patients with advanced cancer: a reanalysis comparing different statistical methods
    Emily Chen
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Pain Symptom Manage 44:23-32. 2012
    ..The clinical relevance of symptom cluster research remains questionable if inconsistencies, partially attributable to the varying statistical analyses used, exist...
  21. ncbi Percutaneous vertebroplasty in patients with intractable pain from osteoporotic or metastatic fractures: A prospective study using quality-of-life assessment
    Gordon Cheung
    Bone Metastases Clinic, Toronto Sunnybrook Regional Cancer Centre, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, ON
    Can Assoc Radiol J 57:13-21. 2006
    ..We prospectively evaluate the efficacy of PVP in the relief of pain and improvement in quality of life of patients with intractable pain from osteoporotic and metastatic fractures...
  22. ncbi Projected referral to other healthcare services in an outpatient palliative radiotherapy clinic
    Janet Nguyen
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, University of Toronto, Toronto, ON, M4N 3M5, Canada
    Expert Rev Pharmacoecon Outcomes Res 12:237-43. 2012
    ..To investigate the projected referral to other healthcare services in an outpatient palliative radiotherapy clinic...
  23. ncbi Fatigue in advanced cancer patients attending an outpatient palliative radiotherapy clinic as screened by the Edmonton Symptom Assessment System
    Liang Zeng
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 20:1037-42. 2012
    ..The purpose of this study was to report the presence, severity, and correlating factors of fatigue in advanced cancer patients attending an outpatient palliative radiotherapy clinic...
  24. ncbi Patients' and health care professionals' evaluation of health-related quality of life issues in bone metastases
    Kristin Harris
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Eur J Cancer 45:2510-8. 2009
    ..This information has been an important component in the development of a health-related quality of life questionnaire for patients with bone metastases (EORTC QLQ-BM 22)...
  25. ncbi Symptom clusters in patients with bone metastases--a reanalysis comparing different statistical methods
    Emily Chen
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 20:2811-20. 2012
    ....
  26. ncbi EORTC QLQ-C15-PAL quality of life scores in patients with advanced cancer referred for palliative radiotherapy
    Amanda Caissie
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 20:841-8. 2012
    ....
  27. ncbi Comparison of pain response and functional interference outcomes between spinal and non-spinal bone metastases treated with palliative radiotherapy
    Liang Zeng
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada
    Support Care Cancer 20:633-9. 2012
    ....
  28. ncbi Physician expectations of treatment outcomes for patients with brain metastases referred for whole brain radiotherapy
    Elizabeth A Barnes
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 76:187-92. 2010
    ..The secondary objectives were to determine the factors influencing the expectations and to examine the accuracy of the physician-estimated patient survival...
  29. ncbi Quality of life in patients with brain metastases treated with a palliative course of whole-brain radiotherapy
    Megan Doyle
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada
    J Palliat Med 10:367-74. 2007
    ..The secondary objective was to assess the level of agreement between patient and proxy quality of life scores...
  30. ncbi Retrospective assessment of cancer pain management in an outpatient palliative radiotherapy clinic using the Pain Management Index
    Gunita Mitera
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada M4N 3M5
    J Pain Symptom Manage 39:259-67. 2010
    ....
  31. ncbi Validation of a predictive model for survival in metastatic cancer patients attending an outpatient palliative radiotherapy clinic
    Edward Chow
    Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 73:280-7. 2009
    ..To validate a predictive model for survival of patients attending a palliative radiotherapy clinic...
  32. ncbi Prophylaxis of radiotherapy-induced nausea and vomiting in the palliative treatment of bone metastases
    Kristopher Dennis
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 20:1673-8. 2012
    ..To document the incidence and timing of radiotherapy-induced nausea and vomiting (RINV) in the treatment of bone metastases among patients receiving prophylaxis with a 5-HT(3) receptor antagonist...
  33. ncbi The palliative performance scale: examining its inter-rater reliability in an outpatient palliative radiation oncology clinic
    Sarah Campos
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Center, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada
    Support Care Cancer 17:685-90. 2009
    ..Currently, it is being used to measure palliative patient performance status in a variety of settings. Despite its widespread use, only one study has examined the inter-rater reliability of the PPS...
  34. ncbi International patterns of practice in palliative radiotherapy for painful bone metastases: evidence-based practice?
    Alysa Fairchild
    Department of Radiation Oncology, Cross Cancer Institute, Edmonton, AB, Canada
    Int J Radiat Oncol Biol Phys 75:1501-10. 2009
    ..However, according to previous surveys, SF schedules remain underused. The objectives of this study were to determine the current patterns of practice internationally and to investigate the factors influencing this practice...
  35. ncbi Has pain management in cancer patients with bone metastases improved? A seven-year review at an outpatient palliative radiotherapy clinic
    Andrea M Kirou-Mauro
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Pain Symptom Manage 37:77-84. 2009
    ....
  36. ncbi Symptoms and quality of life in cancer patients with brain metastases following palliative radiotherapy
    Jennifer Wong
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Canada
    Int J Radiat Oncol Biol Phys 75:1125-31. 2009
    ..To examine prospectively patient self-rated symptoms and quality of life (QOL) indicators in patients with brain metastases following whole brain radiotherapy (WBRT)...
  37. ncbi Continued success of the rapid response radiotherapy program: a review of 2004-2008
    Eric de Sa
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada
    Support Care Cancer 17:757-62. 2009
    ..To update the clinical activity of the Rapid Response Radiotherapy Program (RRRP)...
  38. ncbi Elderly patients with painful bone metastases should be offered palliative radiotherapy
    Sarah Campos
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 76:1500-6. 2010
    ..To investigate the efficacy of palliative radiotherapy (RT) in relieving metastatic bone pain in elderly patients...
  39. ncbi Is response to radiotherapy in patients related to the severity of pretreatment pain?
    Andrea Kirou-Mauro
    Department of Radiation Oncology, Odette Cancer Center, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 71:1208-12. 2008
    ..The primary objective of this study was to determine whether there is a relationship between the severity of pretreatment pain and response to palliative radiotherapy (RT) for painful bone metastases...
  40. ncbi Correlation of computed tomography imaging features with pain response in patients with spine metastases after radiation therapy
    Gunita Mitera
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada M4N 3M5
    Int J Radiat Oncol Biol Phys 81:827-30. 2011
    ..To correlate computed tomography (CT) imaging features of spinal metastases with pain relief after radiotherapy (RT)...
  41. ncbi Quality of life after palliative radiation therapy for patients with painful bone metastases: results of an international study validating the EORTC QLQ-BM22
    Liang Zeng
    Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 84:e337-42. 2012
    ..The purpose of our study was to compare bone metastasis-specific QOL scores among patients who responded differently to palliative RT...
  42. ncbi Do elderly patients with metastatic cancer have worse quality of life scores?
    Kaitlin Koo
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Support Care Cancer 20:2121-7. 2012
    ..The purpose of this study is to compare self-reported quality of life (QOL) scores in old and young patients with metastatic cancer using the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C15-PAL questionnaire...
  43. ncbi Symptom clusters in patients with advanced cancer: sub-analysis of patients reporting exclusively non-zero ESAS scores
    Emily Chen
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Palliat Med 26:826-33. 2012
    ..Varying statistical methods may also contribute to inconsistencies of cluster results...
  44. ncbi International patterns of practice in the management of radiation therapy-induced nausea and vomiting
    Kristopher Dennis
    Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 84:e49-60. 2012
    ..To investigate international patterns of practice in the management of radiation therapy-induced nausea and vomiting (RINV)...
  45. ncbi FACT-Br for assessment of quality of life in patients receiving treatment for brain metastases: a literature review
    Karen Lien
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada
    Expert Rev Pharmacoecon Outcomes Res 11:701-8. 2011
    ..We aim to provide a comprehensive review to examine the use of the FACT-Br as a QoL assessment for patients with brain metastases...
  46. ncbi Subgroups of advanced cancer patients clustered by their symptom profiles: quality-of-life outcomes
    Amna Husain
    Temmy Latner Centre for Palliative Care, Mount Sinai Hospital, Toronto, Ontario, Canada
    J Palliat Med 14:1246-53. 2011
    ..This study clustered patients by their symptom profiles to identify subgroups that may be at higher risk for poor quality of life (QOL) and that may, therefore, benefit most from targeted interventions...
  47. ncbi Rapid improvement in pain and functional level in a patient with metastatic renal cell carcinoma: a case report and review of the literature
    Amanda E Hird
    Rapid Response Radiotherapy Program, Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    J Palliat Med 11:1156-61. 2008
    ..Concurrently, quality of life and performance status improved dramatically. Although we are unsure of the exact mechanism for such rapid improvement in metastatic bone lesions, the swiftness this improvement deserves reporting...
  48. ncbi Involvement of family physicians in the care of cancer patients seen in the palliative Rapid Response Radiotherapy Program
    Elizabeth A Barnes
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, 2075 Bayview Ave, Toronto, Ontario, Canada, M4N 3M5
    J Clin Oncol 25:5758-62. 2007
    ..Secondary objectives were to identify factors predicting for perceived FP involvement in patient cancer care...
  49. ncbi Rare bone metastases of the olecranon
    Shaelyn Culleton
    Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Palliat Med 11:1088-91. 2008
    ..The incidence of olecranon metastasis is extremely rare in all cancers and so far only two cases have been reported in literature. We report the third case of an olecranon metastasis in a patient with renal cell carcinoma...
  50. ncbi Symptom clusters in patients with cancer with metastatic bone pain
    Stephanie Hadi
    Department of Radiation Oncology, Odette Cancer Centre, Toronto, Ontario, Canada
    J Palliat Med 11:591-600. 2008
    ..Secondary objectives were to determine whether symptom clusters change with palliative radiotherapy (RT) and to compare the difference between responders and nonresponders to radiation...
  51. ncbi Quality of life in patients with brain metastases using the EORTC QLQ-BN20+2 and QLQ-C15-PAL
    Amanda Caissie
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 83:1238-45. 2012
    ....
  52. ncbi The EORTC QLQ-BN20 for assessment of quality of life in patients receiving treatment or prophylaxis for brain metastases: a literature review
    Andrew Leung
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Expert Rev Pharmacoecon Outcomes Res 11:693-700. 2011
    ..The European Organization for Research and Treatment of Cancer (EORTC) QLQ-BN20 is a QoL assessment specific to brain neoplasms. We aim to provide a review of the current use of the EORTC QLQ-BN20 for patients with brain metastases...
  53. ncbi Accuracy of survival prediction by palliative radiation oncologists
    Edward Chow
    Division of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Int J Radiat Oncol Biol Phys 61:870-3. 2005
    ..To examine the accuracy of survival prediction by palliative radiation oncologists...
  54. ncbi Prospective assessment of patient-rated symptoms following whole brain radiotherapy for brain metastases
    Edward Chow
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Center, University of Toronto, Toronto, Ontario, Canada
    J Pain Symptom Manage 30:18-23. 2005
    ..0 to 1.8; drowsiness 1.2 to 1.8; and appetite 2.2 to 2.4. The data demonstrate that certain parameters of quality of life worsen after whole brain radiotherapy...
  55. ncbi Symptom clusters in patients with metastatic cancer: a literature review
    Nemica Thavarajah
    Department of Radiation Oncology, Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Expert Rev Pharmacoecon Outcomes Res 12:597-604. 2012
    ..Further exploration in metastatic symptom cluster research will ideally improve patient outcomes by facilitating improved symptom management in future clinical practice...
  56. ncbi A literature review of symptom clusters in patients with breast cancer
    Janet Nguyen
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Expert Rev Pharmacoecon Outcomes Res 11:533-9. 2011
    ....
  57. ncbi Treatment of bone metastases with palliative radiotherapy: patients' treatment preferences
    Ewa Szumacher
    Rapid Response Radiotherapy Program, Bone Metastases Site Group, Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 61:1473-81. 2005
    ..800 cGy in one fraction) for painful bone metastases...
  58. ncbi A multicenter assessment of the adequacy of cancer pain treatment using the pain management index
    Gunita Mitera
    Department of Radiation Therapy, Odette Cancer Center, University of Toronto, Toronto, Ontario, Canada
    J Palliat Med 13:589-93. 2010
    ....
  59. ncbi Computed tomography (CT) evaluation of breast cancer patients with osteolytic bone metastases undergoing palliative radiotherapy--a feasibility study
    Edward Chow
    Rapid Response Radiotherapy Program and Bone Metastases Site Group, Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
    Radiother Oncol 70:291-4. 2004
    ..The median % density change following single 8Gy, 20Gy/5#, 30Gy/10# were: 128 (range 98-255), 141 (79-342), and 145 (65-235), respectively. It is feasible to evaluate remineralization of osteolytic lesions with palliative radiotherapy...
  60. ncbi Exploration of symptoms clusters within cancer patients with brain metastases using the Spitzer Quality of Life Index
    Amanda Hird
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada
    Support Care Cancer 18:335-42. 2010
    ..The objective of this study was to explore the presence of symptom clusters in patients with brain metastases treated with whole brain radiotherapy (WBRT)...
  61. ncbi Comparing prognostic factors in patients with spinal metastases: a literature review
    Marko Popovic
    Department of Radiation Oncology, Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Expert Rev Pharmacoecon Outcomes Res 12:345-56. 2012
    ..For future studies, the authors encourage the development of models capable of inclusion of all patients with spinal metastases...
  62. ncbi Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases
    May N Tsao
    Department ofRadiationOncology, OdetteCancerCentre, Toronto, Canada
    Cochrane Database Syst Rev 4:CD003869. 2012
    ..Brain radiotherapy is used to treat cancer participants who have brain metastases from various primary malignancies.This is an update to the original review published in Issue 3, 2006...
  63. ncbi The role of plain radiographs in management of bone metastases
    Nadia Salvo
    Department of Radiation Oncology, Sunnybrook Odette Cancer Centre, Toronto, Ontario, Canada
    J Palliat Med 12:195-8. 2009
    ..However, plain x-rays can also lead to rare false-positive results. We present a case with a false-positive result in a patient with lung cancer...
  64. ncbi Evaluating correlation and interrater reliability for four performance scales in the palliative care setting
    Jeff Myers
    Palliative Care Consult Team, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5, Canada
    J Pain Symptom Manage 39:250-8. 2010
    ..In addition, given that low levels of exact rater agreement could have substantial clinical implications for patients, we suggest that this parameter be considered in the design of future comparative studies...
  65. ncbi Communication with referring physicians in a palliative radiotherapy clinic
    Elizabeth A Barnes
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, M4 N 3M5, Canada
    Support Care Cancer 12:669-73. 2004
    ..The purpose of this study was to assess how useful referring physicians perceive this interim report and whether this report needs to be modified to meet their information needs...
  66. ncbi An international prospective study establishing minimal clinically important differences in the EORTC QLQ-BM22 and QLQ-C30 in cancer patients with bone metastases
    Liang Zeng
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, Canada, M4N 3M5
    Support Care Cancer 20:3307-13. 2012
    ..The purpose of this study was to establish the minimal clinically important difference (MCID) for the European Organisation for Research and Treatment of Cancer (EORTC) bone metastases module (EORTC QLQ-BM22)...
  67. ncbi Multidisciplinary radiation oncology palliative care rounds as a continuing educational activity implementing the rapid response radiotherapy program at the toronto sunnybrook regional cancer centre
    Ewa Szumacher
    Department of Radiation Oncology, University of Toronto, Ontario, Canada
    J Cancer Educ 18:86-90. 2003
    ....
  68. ncbi Edmonton symptom assessment scale as a prognosticative indicator in patients with advanced cancer
    Liang Zeng
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Canada
    J Palliat Med 14:337-42. 2011
    ..Few studies incorporate patient self-assessment scales in prognostic models of survival prediction. The Edmonton Symptom Assessment Scale (ESAS) is commonly used as a symptom screening tool in cancer patients...
  69. ncbi Self-reported rates of sleep disturbance in patients with symptomatic bone metastases attending an outpatient radiotherapy clinic
    Luluel Khan
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    J Palliat Med 14:708-14. 2011
    ..To examine the reported rates and predictive factors for sleep disturbance in patients with bone metastases...
  70. ncbi Prophylaxis of radiation-induced nausea and vomiting using 5-hydroxytryptamine-3 serotonin receptor antagonists: a systematic review of randomized trials
    Nadia Salvo
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Int J Radiat Oncol Biol Phys 82:408-17. 2012
    ..To systematically review the effectiveness and safety of 5-hydroxytryptamine-3 receptor antagonists (5-HT3 RAs) compared with other antiemetic medication or placebo for prophylaxis of radiation-induced nausea and vomiting...
  71. ncbi Pain flare following external beam radiotherapy and meaningful change in pain scores in the treatment of bone metastases
    Edward Chow
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, Ont M4N 3M5, Canada
    Radiother Oncol 75:64-9. 2005
    ..To examine the incidence of pain flare following external beam radiotherapy and to determine what constitutes a meaningful change in pain scores in the treatment of bone metastases...
  72. ncbi Comparison of the EORTC QLQ-BM22 and the FACT-BP for assessment of quality of life in cancer patients with bone metastases
    Marko Popovic
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, M4N 3M5, ON, Canada
    Expert Rev Pharmacoecon Outcomes Res 12:213-9. 2012
    ..The purpose of this study was to compare the development and characteristics of these two tools, as well as their current use in palliative research...
  73. ncbi International consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases
    Edward Chow
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Ontario, Canada
    Radiother Oncol 64:275-80. 2002
    ..It is intended that the consensus will be re-examined every 5 years. Areas of further research were identified...
  74. ncbi Comparison of the EORTC QLQ-C15-PAL and the FACIT-Pal for assessment of quality of life in patients with advanced cancer
    Karen Lien
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Expert Rev Pharmacoecon Outcomes Res 11:541-7. 2011
    ..Future studies should directly compare these two tools and validate their use through a number of administration modes...
  75. ncbi Radiotherapeutic management of brain metastases: a systematic review and meta-analysis
    May N Tsao
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, 2075 Bayview Avenue, Toronto, Ont, Canada M4N 3M5
    Cancer Treat Rev 31:256-73. 2005
    ..The management of brain metastases is a significant health care problem. An estimated 20-40% of cancer patients will develop metastatic cancer to the brain during the course of their illness...
  76. ncbi Successful salvage using percutaneous vertebroplasty in cancer patients with painful spinal metastases or osteoporotic compression fractures
    Edward Chow
    Bone Metastases Clinic, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Ontario, Canada M4N 3M5
    Radiother Oncol 70:265-7. 2004
    ..Percutaneous vertebroplasty significantly improved pain, mobility and quality of life in cancer patients with bone metastases who failed radiation or with osteoporotic compression fractures. The serious complication is relatively rare...
  77. ncbi Immediate pain relief and improved structural stability after percutaneous vertebroplasty for a severely destructive vertebral compression fracture
    Jennifer Wong
    Rapid Response Radiotherapy Program, Odette Cancer Centre, Toronto, Ontario, Canada
    J Palliat Med 12:97-100. 2009
    ..Percutaneous vertebroplasty provided immediate pain relief and restored structural stability of the diseased vertebra...
  78. ncbi Patient expectation of the partial response and response shift in pain score
    Edward Chow
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Canada
    Support Cancer Ther 4:110-8. 2007
    ..This might become the definition of partial response in future trials. Response shift was observed in this group of patients but in opposing directions and without affecting the overall outcome...
  79. ncbi The not-so-crystal ball: the ongoing challenge of physician prognostication
    Sarah Campos
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    J Psychosom Res 65:67-9. 2008
  80. ncbi What should be the optimal cut points for mild, moderate, and severe pain?
    Kathy K Li
    Department of Radiation Oncology, Odette Cancer Centre, Toronto, Ontario, Canada
    J Palliat Med 10:1338-46. 2007
    ..Thus, the purpose of the current study was to identify optimal cut points (CP) of the three pain severity categories for worst, average, and current pain...
  81. ncbi Symptom control and palliative care content of abstracts presented at the Canadian Association of Radiation Oncologists annual meetings
    Elizabeth A Barnes
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, 2075 Bayview Avenue, Toronto, Ontario, M4 N 3M5, Canada
    Support Care Cancer 12:91-4. 2004
    ..The purpose of this study was to determine the number of abstracts relating to SCPC presented at the annual Canadian Association of Radiation Oncologists (CARO) meetings, and whether this number has increased over time...
  82. ncbi Clinical benefit of reirradiation: a case report
    Candi J Flynn
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada
    J Palliat Med 11:112-6. 2008
  83. ncbi A phase II trial of palliative radiotherapy for metastatic renal cell carcinoma
    Justin Lee
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Cancer 104:1894-900. 2005
    ..Improvements in global pain and QOL appear to be limited by the effects of progressive systemic disease...
  84. ncbi A predictive model for survival in metastatic cancer patients attending an outpatient palliative radiotherapy clinic
    Edward Chow
    Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Canada
    Int J Radiat Oncol Biol Phys 53:1291-302. 2002
    ..To develop a predictive model for survival from the time of presentation in an outpatient palliative radiotherapy clinic...
  85. ncbi Radiotherapeutic approaches to metastatic disease
    Edward Chow
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, 2075 Bayview Avenue, ON M4 N 3M5, Toronto, Canada
    World J Urol 21:229-42. 2003
    ..This article focuses on the management of bone pain and its complications (pathological fractures and spinal cord compression) with radiation treatment...
  86. ncbi Review of telephone follow-up experience at the Rapid Response Radiotherapy Program
    Edward Chow
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Support Care Cancer 13:549-53. 2005
    ..To review the feasibility of telephone follow-up following a 3-year experience from 1999 to 2001 at the Rapid Response Radiotherapy Program as a prospective radiotherapy outcome assessment of symptom palliation...
  87. ncbi Do physicians follow systemic treatment and funding policy guidelines?
    Mark Clemons
    Toronto Sunnybrook Regional Cancer Centre, Canada
    Can J Clin Pharmacol 11:e168-78. 2004
    ..In addition we assessed whether or not physicians at these centres are following their local treatment guidelines and funding policies...
  88. ncbi Successful validation of a survival prediction model in patients with metastases in the spinal column
    Edward Chow
    Department of Radiation Oncology, Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 65:1522-7. 2006
    ..The objective of this study was to validate the Dutch model and compare with our previously developed survival model at the Rapid Response Radiotherapy Program (RRRP model)...
  89. ncbi Utilization of palliative radiotherapy for breast cancer patients with bone metastases treated with bisphosphonates-Toronto Sunnybrook Regional Cancer Centre experience
    Katherine Enright
    University of Western Ontario, London, Ontario, Canada
    Support Care Cancer 12:48-52. 2004
    ..There is a trend of initiating bisphosphonates before delivery of palliative radiotherapy. The latter was also delivered earlier in the course of bone metastases...
  90. ncbi A single set of numerical cutpoints to define moderate and severe symptoms for the Edmonton Symptom Assessment System
    Debbie Selby
    Palliative Care Department, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario M4N 3M5, Canada
    J Pain Symptom Manage 39:241-9. 2010
    ..Across all ESAS symptoms, then, 7 or higher represents a severe symptom by patient definition, whereas a cutpoint of either 4 or 5 could reasonably define combined moderate and severe symptoms...
  91. ncbi Primary treatment endpoint following palliative radiotherapy for painful bone metastases: need for a consensus definition?
    Jackson S Y Wu
    Department of Radiation Oncology, Hamilton Regional Cancer Centre, McMaster University, Ontario, Canada
    Clin Oncol (R Coll Radiol) 14:70-7. 2002
    ....
  92. ncbi Does psychosocial intervention improve survival in cancer? A meta-analysis
    Edward Chow
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    Palliat Med 18:25-31. 2004
    ..A systematic review of randomized trials that have examined the effectiveness of psychosocial intervention in cancer patients in terms of survival prolongation was conducted...
  93. ncbi Symptom distress in patients attending an outpatient palliative radiotherapy clinic
    Nicole Bradley
    Rapid Response Radiotherapy Program, Toronto Sunnybrook Regional Cancer Center, University of Toronto, Toronto, Ontario, Canada
    J Pain Symptom Manage 30:123-31. 2005
    ..Symptom assessment tools, such as the ESAS, allow for the identification of symptoms and their severity. The appropriate regimen for management of pain and symptoms in metastatic cancer patients can then be planned...
  94. ncbi Radiation treatment for breast cancer. Recent advances
    Edward Chow
    Toronto Sunnybrook Regional Cancer Centre, Department of Radiation Oncology, 2075 Bayview Ave, Toronto, ON M4N 3N5
    Can Fam Physician 48:1065-9. 2002
    ..There have been great advances in radiation therapy in the last decade, but they have raised controversy. Further studies are needed to address the controversies...
  95. ncbi Comparison of the efficacy and acute toxicity of weekly versus daily chemoradiotherapy for non-small-cell lung cancer: a meta-analysis
    Eileen Rakovitch
    Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 58:196-203. 2004
    ..It remains unknown whether a difference in efficacy or toxicity exists between these approaches. A systematic review was performed to compare the efficacy and toxicity of weekly vs. daily ChRT...
  96. ncbi Change in urinary markers of osteoclast activity following palliative radiotherapy for bone metastases
    E Chow
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 21:336-42. 2009
    ..To examine the effect of radiotherapy for bone metastases on urinary markers of osteoclast activity...
  97. ncbi Dexamethasone for the prophylaxis of radiation-induced pain flare after palliative radiotherapy for symptomatic bone metastases: a phase II study
    A Hird
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 21:329-35. 2009
    ..A single dose of dexamethasone can decrease the incidence of pain flare during the first 2 days immediately after radiotherapy. We conducted a phase II prospective study to investigate the prophylactic role of prolonged dexamethasone...
  98. ncbi Prospective patient-based assessment of effectiveness of palliative radiotherapy for bone metastases
    E Chow
    Rapid Response Radiotherapy Program, Department of Radiation Oncology, Toronto-Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Avenue, M4N 3M5, Toronto, ON, Canada
    Radiother Oncol 61:77-82. 2001
    ..While randomized trials still remain the gold standard of research, observational studies can serve as useful adjuncts to randomized trials to confirm the efficacy and guide the design of new controlled trials...
  99. ncbi Prognostic factors in brain metastases: can we determine patients who do not benefit from whole-brain radiotherapy?
    M Lock
    Department of Radiation Oncology, London Regional Cancer Centre, University of Western Ontario, London, Ontario, Canada
    Clin Oncol (R Coll Radiol) 16:332-8. 2004
    ..Patients with a short life expectancy may not derive benefit from the addition of radiation. The ability to identify this group would aid the decision of whether to recommend WBRT...
  100. ncbi Whole brain radiotherapy for the treatment of multiple brain metastases
    M N Tsao
    Toronto Sunnybrook Regional Cancer Centre, Department of Radiation Oncology, 2075 Bayview Avenue, Toronto, Ontario, Canada M4N 3M5
    Cochrane Database Syst Rev 3:CD003869. 2006
    ..Brain radiotherapy is used to treat cancer patients who have brain metastases resulting from various primary malignancies...
  101. ncbi Need for better documentation and definition of pain flare following external beam radiotherapy in the treatment of bone metastases
    Kristin Harris
    J Pain Symptom Manage 33:6-8. 2007