E Stip

Summary

Country: Canada

Publications

  1. ncbi request reprint Use of the process dissociation procedure to study the contextual effects on face recognition in schizophrenia: familiarity, associative recollection and discriminative recollection
    Fabrice Guillaume
    Centre de Recherche F Seguin, Hopital Louis H Lafontaine, 7331 rue Hochelaga Montréal, Quebec, Canada
    Psychiatry Res 149:105-19. 2007
  2. ncbi request reprint Rivastigmine treatment as an add-on to antipsychotics in patients with schizophrenia and cognitive deficits
    Sylvie Chouinard
    Department of Psychiatry, Fernand Seguin Research Centre, Louis Hippolyte Lafontaine Hospital, Montreal, Quebec, Canada
    Curr Med Res Opin 23:575-83. 2007
  3. pmc The incidence and nature of cerebellar findings in schizophrenia: a quantitative review of fMRI literature
    Ovidiu Lungu
    Department of Psychiatry, Universite de Montreal, Montreal, Quebec, Canada
    Schizophr Bull 39:797-806. 2013
  4. pmc Neural changes associated with appetite information processing in schizophrenic patients after 16 weeks of olanzapine treatment
    E Stip
    Department of Psychiatry, Universite de Montreal, Montreal, QC, Canada
    Transl Psychiatry 2:e128. 2012
  5. doi request reprint Aripiprazole in schizophrenia and schizoaffective disorder: A review
    Emmanuel Stip
    Centre de Recherche Fernand Seguin, Hopital L H Lafontaine, Universite de Montreal, Quebec, Canada
    Clin Ther 32:S3-20. 2010
  6. ncbi request reprint Cognitive function and depression in symptom resolution in schizophrenia patients treated with an atypical antipsychotic
    Emmanuel Stip
    Fernand Seguin Research Center, Louis H Lafontaine Hospital, University of Montreal, Montreal, Que, Canada
    Brain Cogn 55:463-5. 2004
  7. ncbi request reprint A Canadian multicenter trial assessing memory and executive functions in patients with schizophrenia spectrum disorders treated with olanzapine
    Emmanuel Stip
    Centre de Recherche Fernand Seguin, 7331 rue Hochelaga, Montreal, Quebec, Canada H1N 3V2
    J Clin Psychopharmacol 23:400-4. 2003
  8. ncbi request reprint Intrusion errors in explicit memory: their differential relationship with clinical and social outcome in chronic schizophrenia
    Emmanuel Stip
    Department of Psychiatry, Centre de Recherche Fernand Seguin, Hopital Louis H Lafontaine, Universite de Montreal, Quebec, Canada
    Cogn Neuropsychiatry 12:112-27. 2007
  9. ncbi request reprint [Antipsychotic drugs. Risk factors for diabetes]
    Emmanuel Stip
    Centre de Recherche Fernand Seguin, Montreal, QC
    Presse Med 32:1612-7. 2003
  10. ncbi request reprint [Diabetes and schizophrenia, which links?]
    Emmanuel Stip
    Centre de Recherche Fernand Seguin, Montreal, Quebec
    Presse Med 32:1566-71. 2003

Detail Information

Publications102 found, 100 shown here

  1. ncbi request reprint Use of the process dissociation procedure to study the contextual effects on face recognition in schizophrenia: familiarity, associative recollection and discriminative recollection
    Fabrice Guillaume
    Centre de Recherche F Seguin, Hopital Louis H Lafontaine, 7331 rue Hochelaga Montréal, Quebec, Canada
    Psychiatry Res 149:105-19. 2007
    ..e., delusions and hallucinations...
  2. ncbi request reprint Rivastigmine treatment as an add-on to antipsychotics in patients with schizophrenia and cognitive deficits
    Sylvie Chouinard
    Department of Psychiatry, Fernand Seguin Research Centre, Louis Hippolyte Lafontaine Hospital, Montreal, Quebec, Canada
    Curr Med Res Opin 23:575-83. 2007
    ..Dysfunctions in cholinergic systems, especially in the prefrontal cortex, have been identified in SZ, suggesting that cholinesterase inhibitors may be effective in treating cognitive deficits in this disease...
  3. pmc The incidence and nature of cerebellar findings in schizophrenia: a quantitative review of fMRI literature
    Ovidiu Lungu
    Department of Psychiatry, Universite de Montreal, Montreal, Quebec, Canada
    Schizophr Bull 39:797-806. 2013
    ..Therefore, although the cerebellum seems to play an important functional role in schizophrenia, the lack of reporting and interpretation of these data may hamper the full understanding of the disorder...
  4. pmc Neural changes associated with appetite information processing in schizophrenic patients after 16 weeks of olanzapine treatment
    E Stip
    Department of Psychiatry, Universite de Montreal, Montreal, QC, Canada
    Transl Psychiatry 2:e128. 2012
    ..Furthermore, these changes in neuronal activity correlated with changes in some metabolites and cognitive measurements related to appetite regulation...
  5. doi request reprint Aripiprazole in schizophrenia and schizoaffective disorder: A review
    Emmanuel Stip
    Centre de Recherche Fernand Seguin, Hopital L H Lafontaine, Universite de Montreal, Quebec, Canada
    Clin Ther 32:S3-20. 2010
    ..Aripiprazole is an atypical antipsychotic that has been found to improve positive and negative symptoms of schizophrenia with a favorable adverse-effect profile...
  6. ncbi request reprint Cognitive function and depression in symptom resolution in schizophrenia patients treated with an atypical antipsychotic
    Emmanuel Stip
    Fernand Seguin Research Center, Louis H Lafontaine Hospital, University of Montreal, Montreal, Que, Canada
    Brain Cogn 55:463-5. 2004
    ..To investigate which cognitive and affective features contribute most to responder/non-responder group separation during a switching trial with atypical antipsychotic...
  7. ncbi request reprint A Canadian multicenter trial assessing memory and executive functions in patients with schizophrenia spectrum disorders treated with olanzapine
    Emmanuel Stip
    Centre de Recherche Fernand Seguin, 7331 rue Hochelaga, Montreal, Quebec, Canada H1N 3V2
    J Clin Psychopharmacol 23:400-4. 2003
    ..After switching to olanzapine, there was a statistically significant improvement of cognitive function in the 3 main domains tested and no significant worsening of any memory or executive function measure...
  8. ncbi request reprint Intrusion errors in explicit memory: their differential relationship with clinical and social outcome in chronic schizophrenia
    Emmanuel Stip
    Department of Psychiatry, Centre de Recherche Fernand Seguin, Hopital Louis H Lafontaine, Universite de Montreal, Quebec, Canada
    Cogn Neuropsychiatry 12:112-27. 2007
    ..Memory deficits might account for clinical and adaptive differences between groups of patients with chronic schizophrenia. We investigated the qualitative factors of memory that influence clinical and social status...
  9. ncbi request reprint [Antipsychotic drugs. Risk factors for diabetes]
    Emmanuel Stip
    Centre de Recherche Fernand Seguin, Montreal, QC
    Presse Med 32:1612-7. 2003
    ..The only tendency that has been reproduced in several studies concerns the increased risk associated with dibenzodiazepine antipsychotics (clozapine and olanzapine), compared with the other antipsychotics...
  10. ncbi request reprint [Diabetes and schizophrenia, which links?]
    Emmanuel Stip
    Centre de Recherche Fernand Seguin, Montreal, Quebec
    Presse Med 32:1566-71. 2003
    ....
  11. ncbi request reprint Add-on therapy with acetylcholinesterase inhibitors for memory dysfunction in schizophrenia: a systematic quantitative review, part 2
    Emmanuel Stip
    Centre de Recherche Fernand Seguin, Hechelaga, Montreal, Quebec, Canada
    Clin Neuropharmacol 30:218-29. 2007
    ..Some clinical trials have used add-on therapy with acetylcholinesterase inhibitors (AChEIs) to test the cognitive enhancement effect of this kind of medication, which is usually prescribed for other indications than schizophrenia...
  12. ncbi request reprint Restoration of frontal activation during a treatment with quetiapine: an fMRI study of blunted affect in schizophrenia
    Emmanuel Stip
    Department of Psychiatry, Centre de Recherche Fernand Seguin, Hôpital Louis Hippolyte Lafontaine, Université de Montréal 7331, rue Hochelaga Montréal Québec, Canada H1N 3V2
    Prog Neuropsychopharmacol Biol Psychiatry 29:21-6. 2005
    ..e., passive withdrawal, emotional withdrawal, social avoidance) in schizophrenia...
  13. ncbi request reprint On the trail of a cognitive enhancer for the treatment of schizophrenia
    Emmanuel Stip
    Department of Psychiatry, Centre de Recherche Fernand Seguin, Hôpital Louis Hippolyte Lafontaine, Universite de Montreal, 7331, rue Hochelaga Montréal, Quebec, H1N 3V2, Canada
    Prog Neuropsychopharmacol Biol Psychiatry 29:219-32. 2005
    ..Further meta-analysis of various clinical trials in this field is required to account for matters on the grounds of evidence-based medicine...
  14. ncbi request reprint Psychotic symptoms as a continuum between normality and pathology
    Emmanuel Stip
    Department of Psychiatry, University of Montreal, Montreal, Quebec
    Can J Psychiatry 54:140-51. 2009
    ..It is evident that the creation of a boundary is always possible by using arbitrary criteria that improve interrater reliability but exclude a considerable number of people who share multiple common features with diagnosed people...
  15. doi request reprint Switching from conventional antipsychotics to ziprasidone: a randomized, open-label comparison of regimen strategies
    Emmanuel Stip
    Centre de Recherche Fernand Seguin, Hopital L H Lafontaine, Universite de Montreal, Montreal, Quebec, Canada
    Prog Neuropsychopharmacol Biol Psychiatry 34:997-1000. 2010
    ..However, these differences did not remain significant at endpoint, suggesting that there was no overall difference between the strategies...
  16. ncbi request reprint Environmental cognitive remediation in schizophrenia: ethical implications of "smart home" technology
    Emmanuel Stip
    Centre de Recherche Fernand Seguin, Hopital Louis H Lafontaine, Universite de Montreal, Quebec
    Can J Psychiatry 50:281-91. 2005
    ..In light of the advent of new technologies, we proposed to reexamine certain challenges posed by cognitive remediation and social reintegration (that is, deinstitutionalization) of patients with severe and persistent mental disorders...
  17. pmc Novel antipsychotics: issues and controversies. Typicality of atypical antipsychotics
    E Stip
    Centre de Recherche Fernand Seguin, Hopital L H Lafontaine, Universite de Montreal, Que
    J Psychiatry Neurosci 25:137-53. 2000
    ..Finally, the patient characteristics that define a patient's response to a specific antipsychotic drug are unknown...
  18. ncbi request reprint Neural correlates of sad feelings in schizophrenia with and without blunted affect
    Emmanuel Stip
    Department of Psychiatry, Centre de Recherche Fernand Seguin, Hôpital Luois Hippolyte Lafontaine, Universite de Montreal
    Can J Psychiatry 50:909-17. 2005
    ..We aimed to further investigate this by examining the ventrolateral prefrontal cortex (VLPFC) activation in response to the passive viewing of sad film excerpts...
  19. ncbi request reprint A double-blind, placebo-controlled study of the effects of lithium on cognition in healthy subjects: mild and selective effects on learning
    E Stip
    Centre de Recherche Fernand Seguin, Hopital L H Lafontaine, Universite de Montreal, 7331 Hochelaga, Quebec H1N 3V2, Montreal, Canada
    J Affect Disord 60:147-57. 2000
    ..The aim of the study was to look at the effect of lithium in normal subjects (N=30) taking lithium for 3 weeks. A comprehensive battery was used to assess attention and memory...
  20. ncbi request reprint Cognitive discernible factors between schizophrenia and schizoaffective disorder
    Emmanuel Stip
    Department of Psychiatry, Centre de Recherche Fernand Seguin, Hospital Louis H Lafontaine, Universite de Montreal, Que, Canada
    Brain Cogn 59:292-5. 2005
    ..We hypothesized that, although patients suffering from SA share symptoms with SZ, they can be differentiated on the basis of neurocognitive function and that SA perform better in several domains...
  21. ncbi request reprint Fatal agranulocytosis: the use of olanzapine in a patient with schizophrenia and myelodysplasia
    Emmanuel Stip
    Department of Medicine and Psychiatry, Hopital Louis H Lafontaine, University of Montreal, Montreal, Canada
    Prog Neuropsychopharmacol Biol Psychiatry 31:297-300. 2007
    ..If this patient would have died suddenly without the laboratory investigations that lead to the diagnosis of myeloblastic leukemia, the cause would have been probably and wrongfully allotted to treatment with olanzapine...
  22. pmc Accuracy of the Pepin method to determine appropriate lithium dosages in healthy volunteers
    E Stip
    Centre de recherche Fernand Seguin de l Hôpital Louis H Lafontaine, Universite de Montreal, Montreal, Que
    J Psychiatry Neurosci 26:330-5. 2001
    ..To assess if the lithium dosage prescribed according to the Pepin method leads to therapeutic serum concentrations of lithium...
  23. ncbi request reprint Happy birthday neuroleptics! 50 years later: la folie du doute
    Emmanuel Stip
    Universite de Montreal, Hopital Louis H Lafontaine, Montreal, Canada
    Eur Psychiatry 17:115-9. 2002
    ..Each psychiatrist must continue to be critical, sceptical, optimistic (not overoptimistic) and to learn in order to integrate the positive aspects of our growing knowledge base...
  24. doi request reprint Ziprasidone for psychotic disorders: a meta-analysis and systematic review of the relationship between pharmacokinetics, pharmacodynamics, and clinical profile
    Emmanuel Stip
    Department of Psychiatry, University of Montreal, Montreal, Quebec, Canada
    Clin Ther 33:1853-67. 2011
    ..Among atypical antipsychotics, ziprasidone exhibits a unique clinical profile. However, prescription rates for this medication remain among the lowest of all atypical antipsychotics...
  25. ncbi request reprint Long-term effect of prefrontal lobotomy on verbal fluency in patients with schizophrenia
    Emmanuel Stip
    Fernand Seguin Research Center, Louis H Lafontaine Hospital, University of Montreal, Montreal, Canada
    Brain Cogn 55:466-9. 2004
    ..This study investigated the long-term effects of bilateral prefrontal leukotomy on lexical abilities in schizophrenia subjects...
  26. doi request reprint Increased grey matter densities in schizophrenia patients with negative symptoms after treatment with quetiapine: a voxel-based morphometry study
    Emmanuel Stip
    Department of Psychiatry, Fernand Seguin Research Center, Montreal, Quebec, Canada
    Int Clin Psychopharmacol 24:34-41. 2009
    ..001). Results suggest that increased GMD in some frontal regions are associated with an improvement of negative symptoms. Although not unique to quetiapine, it would be reasonable to attribute the GMD changes in the study to treatment...
  27. ncbi request reprint [Effects of listening to previously hallucinated words by schizophrenia patients in remission: a functional magnetic resonance imaging study of six cases]
    L Ait Bentaleb
    Psychiatre à l Hôpital Louis H Lafontaine et Chercheur Associé au Centre de Recherche Fernand Séguin, 7331 Hochelaga, Montreal, QC, H1N 3V2, Canada
    Encephale 32:27-40. 2006
    ..The specific content of AVHs persists across different psychotic episodes even after extended periods of remission. Furthermore, the AVHs are usually triggered by emotionally charged and stressful situations...
  28. ncbi request reprint Abnormal prefrontal and anterior cingulate activation in major depressive disorder during episodic memory encoding of sad stimuli
    C Fahim
    Centre de recherche Fernand Séguin and Hôpital Louis Hippolyte Lafontaine, Montreal, Quebec, Canada
    Brain Cogn 54:161-3. 2004
  29. doi request reprint The complex relationships between executive functions and positive symptoms in schizophrenia
    F Guillem
    Fernand Seguin Research Centre, L H Lafontaine Hospital and Department of Psychiatry, University of Montreal, Montreal, Canada
    Psychol Med 38:853-60. 2008
    ..In this study, we have investigated the relationships between different aspects of positive symptomatology and several executive subprocesses...
  30. ncbi request reprint [Cognition, schizophrenia and the effect of antipsychotics]
    E Stip
    Universite de Montreal, Chaire de Schizophrénie, Centre de Recherche Fernand Seguin, Hopital Louis H Lafontaine, Hôpital Sacré Coeur de Montréal, 7331, rue Hochelaga, Montreal, Quebec H1N 3V2
    Encephale 32:341-50. 2006
    ..Procedural learning is rarely assessed in clinical practice. Inconsistent findings regarding the effects of neuroleptic drugs on PL have been reported...
  31. ncbi request reprint Negative socio-emotional resonance in schizophrenia: a functional magnetic resonance imaging hypothesis
    C Fahim
    Department of Neurological Sciences, Faculty of Medicine, Universite de Montreal, Centre de Recherche Fernand Seguin, 7331 rue Hochelaga, Montreal, Que, Canada H1N 3V2
    Med Hypotheses 63:467-75. 2004
    ..This could be due to genetic or other endogenous causes, which affected prefrontal cortex MN involved in emotional resonance...
  32. doi request reprint Daily activities, cognition and community functioning in persons with schizophrenia
    Ginette Aubin
    Centre hospitalier de l Université de Montréal CHUM Hôpital Notre Dame, and School of Physical and Occupational Therapy, McGill University, 3654 Promenade Sir William Osler, Montreal, QC, Canada, H3G 1Y5
    Schizophr Res 107:313-8. 2009
    ..More specifically, this study attempted to verify the hypothesis that functional limitations in the performance of daily activities negatively affect community functioning in people with schizophrenia...
  33. doi request reprint Working memory and depressive symptoms in patients with schizophrenia and substance use disorders
    Stephane Potvin
    Fernand Seguin Research Center, University of Montreal, Montreal, Canada
    Cogn Neuropsychiatry 13:357-66. 2008
    ..Regarding cognition, the prevailing literature has produced mixed results. Some groups have reported greater cognitive impairments in dual diagnosis schizophrenia, while other groups have described the reverse...
  34. ncbi request reprint Memory and attention deficits in drug naive patients with schizophrenia
    I Lussier
    Centre de recherche Fernand-Seguin, , , 7331 rue Hochelaga, Que. H1N 3V2, Montreal, Canada
    Schizophr Res 48:45-55. 2001
    ..Results support the idea that an important part of the impairments seen in schizophrenia is present before the introduction of neuroleptic medication and chronic illness...
  35. pmc Increased extrapyramidal symptoms in patients with schizophrenia and a comorbid substance use disorder
    S Potvin
    Centre de Recherche Fernand Seguin, Hopital Louis H Lafontaine, 7331, rue Hochelaga, Montreal, Quebec, Canada H1N 3V2
    J Neurol Neurosurg Psychiatry 77:796-8. 2006
    ..Analyses of variance were conducted on both groups and showed that schizophrenia patients with a comorbid substance use disorder (especially cocaine) displayed more EPS compared with non-abusing patients...
  36. ncbi request reprint Leukotomy revisited: late cognitive and behavioral effects in chronic institutionalized schizophrenics
    D N Black
    Universite de Montreal, Centre de Recherche Fernand Seguin, Louis Hippolyte Lafontaine Hospital, Quebec H1N 3V2, Montreal, Canada
    Schizophr Res 43:57-64. 2000
    ..Subsequent observations have confirmed its ineffectiveness in schizophrenia. Few studies have addressed its long-term consequences...
  37. ncbi request reprint Sleep architecture and its clinical correlates in first episode and neuroleptic-naive patients with schizophrenia
    Julie Poulin
    Centre de Recherche Fernand Seguin, Hôpital Louis H Lafontaine and Département de psychiatrie, Universite de Montreal, Canada
    Schizophr Res 62:147-53. 2003
    ..The fact that measures of REM sleep correlate with clinical scales of schizophrenia suggests that REM sleep physiology shares common substrates with symptoms of this disease...
  38. ncbi request reprint Clozapine, quetiapine and olanzapine among addicted schizophrenic patients: towards testable hypotheses
    Stephane Potvin
    Clinique Cormier Lafontaine, Montreal, Quebec, Canada
    Int Clin Psychopharmacol 18:121-32. 2003
    ....
  39. ncbi request reprint Attention and non-REM sleep in neuroleptic-naive persons with schizophrenia and control participants
    Geneviève Forest
    Centre de Recherche Fernand Seguin, Hopital Louis H Lafontaine, 7331 Hochelaga, Montreal, Quebec, Canada H1N 3V2
    Psychiatry Res 149:33-40. 2007
    ..These results support the existence of a relationship between non-rapid-eye-movement sleep and cognitive performance in healthy individuals as well as in persons with schizophrenia...
  40. ncbi request reprint Neural correlates of the affect regulation model in schizophrenia patients with substance use history: a functional magnetic resonance imaging study
    Adham Mancini-Marie
    Department of Psychiatry, Fernand Seguin Research Center, Louis H Lafontaine Hospital, University of Montreal, Montreal, Quebec, Canada
    J Clin Psychiatry 67:342-50. 2006
    ..We hypothesized that patients with a history of substance use would have increased cerebral activations in response to aversive stimuli when compared to abstinent patients...
  41. doi request reprint Neuronal correlates of appetite regulation in patients with schizophrenia: is there a basis for future appetite dysfunction?
    O Lungu
    Departement de Psychiatrie, Universite de Montreal, Montreal, Quebec, Canada
    Eur Psychiatry 28:293-301. 2013
    ..Given the undesired metabolic side effects of atypical antipsychotic medication it is important to understand the neuronal basis related to processing of appetite regulation in patients affected by schizophrenia...
  42. doi request reprint Preserved awareness of their cognitive deficits in patients with schizophrenia: convergent validity of the SSTICS
    Laurent Lecardeur
    Department of Psychiatry, Centre de Recherche Fernand Seguin, Hopital Louis H Lafontaine, Universite de Montreal, Montreal, Quebec, Canada
    Schizophr Res 107:303-6. 2009
    ..They also reveal good concordance between cognitive impairments experienced by patients and cognitive disorders assessed by a clinical rater...
  43. ncbi request reprint Exploring cognitive complaints in schizophrenia: the subjective scale to investigate cognition in schizophrenia
    E Stip
    Universite de Montreal, QC, Canada
    Compr Psychiatry 44:331-40. 2003
    ..Validation of the SSTICS needs to be completed through further exploration of the factorial structure and testing of the English version...
  44. ncbi request reprint Fusiform gyrus and possible impairment of the recognition of emotional expression in schizophrenia subjects with blunted affect: a fMRI preliminary report
    A Mancini-Marie
    Centre de Recherche Fernand Segun de l Hôpital Louis H, Lafontaine, University de Montreal, Montreal, Que, Canada
    Brain Cogn 54:153-5. 2004
  45. ncbi request reprint Changes in distributed neural circuitry function in patients with first-episode schizophrenia
    A Mendrek
    Department of Psychiatry, University of Montreal, Centre de Recherche Fernand Seguin, 7331 Hochelaga, Montreal, Quebec H1N 3V2, Canada
    Br J Psychiatry 185:205-14. 2004
    ..A number of functional brain abnormalities have been reported in schizophrenia, but it remains to be determined which of them represent trait and state markers of the illness...
  46. doi request reprint Correlations between sadness-induced cerebral activations and schizophrenia symptoms: an fMRI study of sex differences
    A Mendrek
    Department of Psychiatry, Centre de Recherche Fernand Seguin, Louis H Lafontaine Hospital, University of Montreal, 7331 Hochelaga, Montréal QC H1N 3V2, Canada
    Eur Psychiatry 26:320-6. 2011
    ..The aim of the present study was to investigate the relationship between cerebral activations during exposure to emotional material and schizophrenia symptoms in men versus women...
  47. ncbi request reprint Contradictory cognitive capacities among substance-abusing patients with schizophrenia: a meta-analysis
    Stephane Potvin
    Fernand Seguin Research Center, University of Montreal, Montreal, Canada
    Schizophr Res 100:242-51. 2008
    ..It is concluded that previous mixed results obtained with cognitive evaluations of persons with Sz+SUD might reflect the heterogeneity of participants and that subgroups of patients might be defined on the basis of intermediate factors...
  48. ncbi request reprint Anhedonia and social adaptation predict substance abuse evolution in dual diagnosis schizophrenia
    Stephane Potvin
    Fernand Seguin Research Center, Louis H Lafontaine Hospital, Montreal, Canada
    Am J Drug Alcohol Abuse 34:75-82. 2008
    ..Further studies are warranted to dissociate the causes and consequences of substance abuse in schizophrenia...
  49. pmc Influence of comorbid obsessive-compulsive symptoms on brain event-related potentials in Gilles de la Tourette syndrome
    Genevieve Thibault
    Centre de recherche Fernand Seguin of the Hôpital Louis H Lafontaine, 7331 Hochelaga, Montreal, Quebec, Canada H1N 3V2
    Prog Neuropsychopharmacol Biol Psychiatry 32:803-15. 2008
    ..The discrepancy between our findings and results obtained in previous studies on GTS could reflect the modulating effect of OCS on late ERP components...
  50. pmc Electrophysiological manifestations of stimulus evaluation, response inhibition and motor processing in Tourette syndrome patients
    Genevieve Thibault
    Centre de recherche Fernand Seguin and Hôpital Louis H Lafontaine, Montreal, Quebec, Canada
    Psychiatry Res 167:202-20. 2009
    ..Our findings are congruent with a probable cortical motor over-activation hypothesis of GTS involving faster motor program selection in processing conflicting SR configuration...
  51. ncbi request reprint Genes and memory: the neuroanatomical correlates of emotional memory in monozygotic twin discordant for schizophrenia
    Cherine Fahim
    Department of Neurological Sciences, Faculty of Medicine, Universite de Montreal, Canada
    Brain Cogn 55:250-3. 2004
    ..In this paradigm, the difference score and reaction time between the unaffected member and affected member of a twin pair should represent the degree of pathologic involvement irrespective of actual level...
  52. doi request reprint Effects of cognitive remediation therapies on psychotic symptoms and cognitive complaints in patients with schizophrenia and related disorders: a randomized study
    Laurent Lecardeur
    Pavillon Albert Prévost, Hopital du Sacre Coeur de Montreal, Montreal, Quebec, Canada
    Schizophr Res 111:153-8. 2009
    ..Cognitive remediation therapy (CRT) has proven to be effective in treating cognitive deficits in schizophrenia. The current study aimed to assess the efficacy of CRT on psychotic symptoms and cognitive complaints...
  53. doi request reprint The long-term clinical benefit and effectiveness of switching to once-daily quetiapine extended release in patients with schizophrenia
    P Chue
    Department of Psychiatry, Faculty of Medicine, University of Alberta, 9942 108 Street, Edmonton, Alberta T5K 2J5, Canada
    Curr Med Res Opin 29:227-39. 2013
    ..The primary endpoint was the percentage of patients achieving an improvement in Clinical Global Impression - Clinical Benefit (CGI-CB) scale scores...
  54. ncbi request reprint ["What's up, doc?" The context, limitations, and issues for clinicians in evidence-based medicine]
    A D Lesage
    Universite de Montreal, Centre de Recherche Fernand Seguin, Hopital L H Lafontaine, 7331, rue Hochelaga, Montréal QC H1N 3V2
    Can J Psychiatry 46:396-402. 2001
    ..The evidence-based medicine approach could be considered a new name given to the contemporary medicine dialectics between the practice of an art and the insight provided by the best scientific data...
  55. ncbi request reprint [Hypofrontality and negative symptoms in schizophrenia: synthesis of anatomic and neuropsychological knowledge and ecological perspectives]
    M Semkovska
    Centre de recherche Fernand-Seguin, , 7331, rue Hochelaga, , QC, H1N 3V2, Canada
    Encephale 27:405-15. 2001
    ....
  56. doi request reprint Endogenous cannabinoids in patients with schizophrenia and substance use disorder during quetiapine therapy
    Stephane Potvin
    Fernand Seguin Research Center, Louis H Lafontaine Hospital and Biomedical Sciences Program, Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada
    J Psychopharmacol 22:262-9. 2008
    ..Lastly, baseline anandamide predicted endpoint SUD scores (alcohol/ cannabis). Anandamide is a potential target for medications aimed at relieving SUD in schizophrenia...
  57. ncbi request reprint CANTAB explicit memory is less impaired in addicted schizophrenia patients
    Stephane Potvin
    Centre de Recherche Fernand Seguin, Hopital Louis H Lafontaine, 7331 rue Hochelaga, Montreal, Que, Canada H1N 3V2
    Brain Cogn 59:38-42. 2005
    ..Our results suggest either that substance abuse relieves the cognitive deficits of schizophrenia or that the patients with less cognitive deficits are more prone to substance abuse...
  58. ncbi request reprint Pain perception in schizophrenia: no changes in diffuse noxious inhibitory controls (DNIC) but a lack of pain sensitization
    Stephane Potvin
    Centre de Recherche Fernand Seguin, University of Montreal, Montreal, Canada
    J Psychiatr Res 42:1010-6. 2008
    ..Preliminary experimental studies have shown diminished pain sensitivity in schizophrenia patients. The objective of the study was to investigate the role of excitatory and inhibitory systems on pain perception in schizophrenia...
  59. ncbi request reprint The paradox of quetiapine in obsessive-compulsive disorder
    Constantin Tranulis
    Department of Psychiatry, Louis H Lafontaine Hospital, Montreal, Canada
    CNS Spectr 10:356-61. 2005
    ..The discussion emphasizes the prognostic implications of OCS in schizophrenia and available therapies for this comorbidity...
  60. ncbi request reprint Quetiapine augmentation of treatment-resistant depression: a comparison with lithium
    Jean Pierre Dorée
    Centre Hospitalier Pierre Legardeur, Montreal, Quebec, Canada
    Curr Med Res Opin 23:333-41. 2007
    ..In this study, quetiapine was compared with lithium in the augmentation of treatment-resistant depression...
  61. ncbi request reprint Oral cholinesterase inhibitor add-on therapy for cognitive enhancement in schizophrenia: a quantitative systematic review, Part I
    Sylvie Chouinard
    Centre de Recherche Fernand Seguin, Hopital Louis H Lafontaine, Canada
    Clin Neuropharmacol 30:169-82. 2007
    ..Some clinical trials have used acetylcholinesterase inhibitors (AChEIs) add-on therapy to test the cognitive-enhancing effects of these kinds of medication, which is usually prescribed for indications other than schizophrenia...
  62. doi request reprint Do patients with schizophrenia attribute mental states in a referential communication task?
    Maud Champagne-Lavau
    Hôpital du Sacré Caeur de Montréal, Pavillon Albert Prévost, 6555 Gouin Blvd West, Montreal, Quebec H4K 1B3, Canada
    Cogn Neuropsychiatry 14:217-39. 2009
    ..The aim of this study was to assess ToM ability using both a classical task and a referential communication task that reproduces a ''natural'' conversation situation...
  63. doi request reprint Temperament and executive dysfunctions in schizophrenia
    Francois Guillem
    Fernand Seguin Research Centre, L H Lafontaine Hospital, Montreal, QC, Canada H1N 3V2
    Schizophr Res 104:175-84. 2008
    ..These results suggest that the temperamental profile of schizophrenia patients may well be of important prognostic value in the planning of cognitive enhancement therapy...
  64. doi request reprint Sexual dimorphism of spatial working memory profiles in schizophrenia
    Laurent Lecardeur
    Department of Psychiatry, Centre de Recherche Fernand Seguin, Hopital Louis H Lafontaine, Universite de Montreal, Montreal, Quebec, Canada
    Cogn Neuropsychiatry 15:397-405. 2010
    ....
  65. ncbi request reprint The relationships between symptom dimensions and dysphoria in schizophrenia
    Francois Guillem
    Fernand Seguin Research Centre, L H Lafontaine Hospital and Department of Psychiatry, University of Montreal, 7331 rue Hochelaga, Montreal, Quebec, Canada, H1N 3V2
    Schizophr Res 75:83-96. 2005
    ..Our data further suggested that these associations may be best understood in terms of interactions between various processing biases alluded in the most recent cognitive accounts of schizophrenia symptoms...
  66. ncbi request reprint Meta-analysis of depressive symptoms in dual-diagnosis schizophrenia
    Stephane Potvin
    Fernand Seguin Research Centre, University of Montreal, Montreal, Canada
    Aust N Z J Psychiatry 41:792-9. 2007
    ..These results have methodological implications for future studies of depressive symptoms in dual-diagnosis patients, and potential implications for the prevention and treatment of depressive symptoms in schizophrenia...
  67. ncbi request reprint Cognitive-behaviour therapy and skilled motor performance in adults with chronic tic disorder
    Kieron P O'Connor
    Centre de Recherche Fernand Seguin, Hopital Louis H Lafontaine, Montreal, Quebec, Canada
    Neuropsychol Rehabil 18:45-64. 2008
    ..Cognitive-behavioural treatment selectively improved motor performance in both clinical groups compared to waitlist control, and this improvement related to clinical outcome measures...
  68. pmc Cognitive behavioral management of Tourette's syndrome and chronic tic disorder in medicated and unmedicated samples
    Kieron P O'Connor
    Fernand Seguin Research Centre, Louis H Lafontaine Hospital 7331 Hochelaga St Montreal Quebec H1N 3V2 Canada
    Behav Res Ther 47:1090-5. 2009
    ..The current study compares the efficacy of CBT in combination with medication and without medication...
  69. doi request reprint Relationship between psychotic and obsessive compulsive symptoms in schizophrenia
    Francois Guillem
    Departement de Psychiatrie, Université de Montréal 7331 Hochelaga, Centre de Recherche F Seguin, Hopital L H Lafontaine, Montreal, QC, Canada
    Schizophr Res 115:358-62. 2009
    ..These results may reflect that these OCSs have a protective effect against disorganization and psychotic symptoms respectively...
  70. ncbi request reprint Changes in the neuropsychological correlates of clinical dimensions between the acute and stable phase of schizophrenia
    Francois Guillem
    Centre de Recherche F Seguin, Hopital L H Lafontaine, 7331, rue Hochelaga, Montreal, Que, H1N 3V2, Canada
    Brain Cogn 57:93-101. 2005
    ..The results also suggest that functional changes related to some symptoms dimensions occur to compensate for the dysfunction associated with other symptoms...
  71. doi request reprint Sex differences in memory processing in schizophrenia: an event-related potential (ERP) study
    Francois Guillem
    Centre de Recherche F Seguin Hôpital L H Lafontaine, 7331, rue Hochelaga, Montreal, Quebec, Canada H2L 1L8
    Prog Neuropsychopharmacol Biol Psychiatry 33:1-10. 2009
    ..These results indicate that the influence of sex on the cognitive impairment in schizophrenia is not homogenous across the information-processing cascade...
  72. ncbi request reprint Treating delusional disorder: a comparison of cognitive-behavioural therapy and attention placebo control
    Kieron O'Connor
    Fernand Seguin Research Centre, Montreal, Quebec
    Can J Psychiatry 52:182-90. 2007
    ..This current study aimed to assess patients with DD who received CBT, compared with an attention placebo control (APC) group...
  73. ncbi request reprint Are cholinergic enhancers beneficial for memory in schizophrenia? An event-related potentials (ERPs) study of rivastigmine add-on therapy in a crossover trial
    Francois Guillem
    Centre de Recherche Fernand Seguin, Hopital L H Lafontaine, Montreal, QC, Canada H1N 3V2
    Prog Neuropsychopharmacol Biol Psychiatry 30:934-45. 2006
    ..Generally, this study showed that the beneficial effect of rivastigmine on memory is not unitary but rather comes from its action at different time points within information processing cascade...
  74. ncbi request reprint Quetiapine in patients with comorbid schizophrenia-spectrum and substance use disorders: an open-label trial
    Stephane Potvin
    Centre de Recherche Fernand Seguin, Hopital Louis H Lafontaine, Montreal, Canada
    Curr Med Res Opin 22:1277-85. 2006
    ..Quetiapine shares crucial pharmacological properties with clozapine. Promising results have been described with quetiapine therapy in patients with psychosis and substance use disorder...
  75. ncbi request reprint Brain-behavior relations during motor processing in chronic tic and habit disorder
    Kieron P O'Connor
    Hôpital Louis H Lafontaine and Centre de Recherche Fernand Seguin, Departement de Psychiatrie, Universite de Montreal, Montreal, Quebec, Canada
    Cogn Behav Neurol 18:79-88. 2005
    ....
  76. ncbi request reprint Computerized assessment of cognition in schizophrenia: promises and pitfalls of CANTAB
    Marie Noëlle Levaux
    Centre de Recherche Fernand Seguin, Hopital Louis H Lafontaine, Montreal, Quebec, Canada
    Eur Psychiatry 22:104-15. 2007
    ..A clear approach concerning the usage of CANTAB for the appraisal of neurocognitive dysfunction in schizophrenia is currently lacking...
  77. ncbi request reprint Predictors of quality of life in schizophrenia
    Jean Caron
    Department of Psychiatry, Douglas Hospital Research Centre, McGill University, 6875 LaSalle Blvd, Verdun, QC, Canada, H4H 1R3
    Community Ment Health J 41:399-417. 2005
    ..Severity of daily hassles, the coping strategy of changing the situation, level of education and life-time hospitalization length were also related to QOL...
  78. ncbi request reprint Differential hemodynamic brain activity in schizophrenia patients with blunted affect during quetiapine treatment
    Cherine Fahim
    Department of Neurological Sciences, Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada
    J Clin Psychopharmacol 25:367-71. 2005
    ..Unique BOLD changes in the putamen and DLPFC with quetiapine, in the BA+ postquetiapine, may reflect modality-specific effects. Controlled studies are needed to further assess these preliminary findings...
  79. ncbi request reprint Sex differences in the cerebral function associated with processing of aversive stimuli by schizophrenia patients
    Adrianna Mendrek
    Department of Psychiatry, Universite de Montreal, Centre de Recherche Fernand Seguin, 7331 Hochelaga, Montreal, QC, H1N 3V2, Canada
    Aust N Z J Psychiatry 41:136-41. 2007
    ..The aim of the present study was to explore this phenomenon during exposure to aversive stimuli...
  80. ncbi request reprint Are there common mechanisms in sensation seeking and reality distortion in schizophrenia? A study using memory event-related potentials
    Francois Guillem
    Centre de Recherche F Seguin, Hopital L H Lafontaine, 7331, rue Hochelaga, Montreal, Quebec, H2L 1L8, Canada
    Psychiatry Res 135:11-33. 2005
    ..In summary, the present study examines the strategy of investigating variables, such as temperamental characteristics, in addition to symptoms, to show how discrete impairments may contribute to the expression of the illness...
  81. pmc Memory and executive functions in adults with Gilles de la Tourette syndrome and chronic tic disorder
    Marc E Lavoie
    Centre de recherche Fernand Seguin and Hôpital Louis H Lafontaine, Departement de Psychiatrie, Universite de Montreal, Canada
    Cogn Neuropsychiatry 12:165-81. 2007
    ..Still, it is not clear whether neuropsychological performances are affected to the same degree in adults with TS and CTD...
  82. ncbi request reprint [Schizophrenia and addiction: An evaluation of the self-medication hypothesis]
    S Potvin
    Universite de Montreal, Clinique Cormier Lafontaine toxicomanie santé mentale, 110 ouest, rue Prince Arthur, Montreal, Qc H2X 1S7
    Encephale 29:193-203. 2003
    ....
  83. ncbi request reprint Atypical memory performance in an autistic savant
    L Mottron
    Hôpital Rivière des Prairies, Montreal, Quebec, Canada
    Memory 6:593-607. 1998
    ..The findings suggest that the outstanding episodic memory presented by some savant persons with autism might be related to an abnormally high resistance to interference...
  84. ncbi request reprint Including integrated psychological treatment as part of standard medical therapy for patients with schizophrenia: clinical outcomes
    Catherine Briand
    Centre de Recherche Fernand Seguin of Hôpital Louis H Lafontaine, Montreal, Canada
    J Nerv Ment Dis 194:463-70. 2006
    ..Our experience in nine clinical settings suggests that IPT can successfully be included as part of standard medical therapy in the rehabilitation of patients with schizophrenia...
  85. ncbi request reprint A meta-analysis of negative symptoms in dual diagnosis schizophrenia
    Stephane Potvin
    Centre de Recherche Fernand Seguin, Hopital Louis H Lafontaine, Psychiatry Department, Faculty of Medicine, University of Montreal, Canada
    Psychol Med 36:431-40. 2006
    ..One potential confounding factor for this discrepancy lies in the diverse scales used to evaluate the negative symptoms. A systematic quantitative review of the literature using computerized search engines has been undertaken...
  86. ncbi request reprint Increased striatal gray matter densities in patients with schizophrenia and substance use disorder: a voxel-based morphometry study
    Stephane Potvin
    Department of Psychiatry, Fernand Seguin Research Center, University of Montreal, Canada
    Psychiatry Res 154:275-9. 2007
    ..Increased striatal GMD were found in patients with schizophrenia and substance use disorder (n=12), but not schizophrenia only patients (n=11), compared to healthy volunteers (n=15)...
  87. ncbi request reprint Evaluation of a cognitive-behavioural program for the management of chronic tic and habit disorders
    M Brault
    Fernand-Seguin Research Centre, Hĵpital-Louis-H Lafontaine and University of Montreal, Quebec, Canada
    Behav Res Ther 39:667-81. 2001
    ..Successful tic/habit modification was associated in CTD and HD groups with successful change in style of planning action. There were no consistent differences in any outcome measures between CTD and HD groups...
  88. ncbi request reprint Clozapine alone versus clozapine and risperidone with refractory schizophrenia
    William G Honer
    Centre for Complex Disorders and the Department of Psychiatry, University of British Columbia, Vancouver General Hospital Research Pavilion, Vancouver, Canada
    N Engl J Med 354:472-82. 2006
    ..The treatment of schizophrenia with multiple antipsychotic drugs is common, but the benefits and risks are not known...
  89. ncbi request reprint Mild procedural learning disturbances in neuroleptic-naive patients with schizophrenia
    Hélène Schérer
    Cognitive Neuroscience Center, Universite du Quebec a Montreal, Canada
    J Neuropsychiatry Clin Neurosci 15:58-63. 2003
    ..However, this dysfunction is not severe enough to prevent learning...
  90. ncbi request reprint Comorbid substance-use in schizophrenia: the file drawer effect, In reply to: Talamo et al., 2006. "Comorbid substance-use in schizophrenia: relation to positive and negative symptoms"
    Stephane Potvin
    Schizophr Res 90:351-2; author reply 353-4. 2007
  91. ncbi request reprint Self-assessed cognitive dysfunction and objective performance in outpatients with schizophrenia participating in a rehabilitation program
    Antoinette Prouteau
    Department of Psychiatry, IFR of Public Health, University Victor Segalen, Bordeaux 2, France
    Schizophr Res 69:85-91. 2004
    ..To explore the pattern of associations between self-assessed and objective neuropsychological performance in a sample of outpatients with schizophrenia participating in a rehabilitation program...
  92. pmc Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment
    Ric M Procyshyn
    Department of Research, Riverview Hospital, Port Coquitlam, BC, Canada
    J Psychiatry Neurosci 32:331-8. 2007
    ..The primary objective of this study was to determine whether an increase in serum lipids is associated with improvement in schizophrenia symptoms during steady state treatment with clozapine...
  93. ncbi request reprint Does hyperpriming reveal impaired spreading of activation in schizophrenia?
    Laurent Lecardeur
    Schizophr Res 97:289-91. 2007
  94. ncbi request reprint Neuropsychological and activity of daily living script performance in patients with positive or negative schizophrenia
    Lucie Godbout
    Departement de Psychologie, Universite du Quebec a Trois Rivieres, Quebec, Canada G4A 5H7
    Compr Psychiatry 48:293-302. 2007
    ....
  95. ncbi request reprint The crucial role of sustained attention in community functioning in outpatients with schizophrenia
    Antoinette Prouteau
    EA 3676 and JE 2358, IFR of Public Health, University Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    Psychiatry Res 129:171-7. 2004
    ..Measures of such processes could serve as key indices of disability in clinical practice. Attention and working memory training may be helpful to improve community functioning in subjects with schizophrenia...
  96. ncbi request reprint The contribution of a modified transactional model to the adaptation of schizophrenics living in the city of Montreal
    Yves Lecomte
    Schizophr Res 72:279-81. 2005
  97. ncbi request reprint Cognitive predictors of psychosocial functioning outcome in schizophrenia: a follow-up study of subjects participating in a rehabilitation program
    Antoinette Prouteau
    INSERM U657 and JE 2358, IFR of Public Health, University Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    Schizophr Res 77:343-53. 2005
    ..These cognitive functions could be specifically targeted in a rehabilitation program aimed at enhancing functioning in those particular dimensions...
  98. ncbi request reprint The effect of quetiapine on cannabis use in 8 psychosis patients with drug dependency
    Stephane Potvin
    Can J Psychiatry 49:711. 2004
  99. ncbi request reprint Assessment of executive dysfunction during activities of daily living in schizophrenia
    Maria Semkovska
    Cognitive Neuroscience Center, Universite du Quebec a Montreal, Canada
    Schizophr Res 69:289-300. 2004
    ..These results suggest that executive deficits in schizophrenia may specifically affect ADL and that such deficits can be quantitatively assessed with a behavioral scale of action sequences...
  100. ncbi request reprint Procedural learning in schizophrenia can reflect the pharmacologic properties of the antipsychotic treatments
    Hélène Schérer
    Cognitive Neuroscience Center, Universite du Quebec a Montreal, Canada
    Cogn Behav Neurol 17:32-40. 2004
    ..Given that this cerebral structure was previously found to play a major role in procedural learning, the antipsychotic treatment in schizophrenia may be determinant for the procedural learning profile of these patients...
  101. ncbi request reprint ERP study of pre-attentive auditory processing in treatment-refractory schizophrenia
    Denise L Milovan
    Department of Psychology, Concordia University, Centre de Recherche Fernand Seguin, Canada H3A 2B4
    Brain Cogn 55:355-7. 2004
    ..These findings are consistent with pre-attentive abnormalities in treatment-refractory patients with schizophrenia...