Affiliation: St. Michael's Hospital
- Development and psychometric evaluation of the pediatric anesthesia emergence delirium scaleNancy Sikich
St Michael s Hospital, Department of Anesthesia, 30 Bond Street, Toronto, Ontario, Canada
Anesthesiology 100:1138-45. 2004..However, no reliable and valid rating scale exists to measure this phenomenon in children. Therefore, the authors developed and evaluated the Pediatric Anesthesia Emergence Delirium (PAED) scale to measure emergence delirium in children...
- A phase I, two-center study of the pharmacokinetics and pharmacodynamics of dexmedetomidine in childrenGuy C Petroz
Department of Anaesthesia, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Anesthesiology 105:1098-110. 2006..To investigate dexmedetomidine in children, the authors performed an open-label study of the pharmacokinetics and pharmacodynamics of dexmedetomidine...
- Severe hemodilutional anemia increases cerebral tissue injury following acute neurotraumaGregory M T Hare
Department of Anesthesia, University of Toronto, St Michael s Hospital, 30 Bond St, Toronto, Ontario M5B 1W8, Canada
J Appl Physiol (1985) 103:1021-9. 2007..05 for both). Hemodilutional anemia reduced cerebral Pbr(O(2)) and oxygen extraction and increased cell death following TBI. These results support our hypothesis that acute anemia accentuated hypoxic cerebral injury after neurotrauma...
- Effects of resuscitation fluid on neurologic physiology after cerebral trauma and hemorrhageAndrew J Baker
Cara Phelan Center for Trauma Research, Department of Anaesthesia, St Michael s Hospital, Toronto, Ontario, Canada
J Trauma 64:348-57. 2008..Guidelines for the choice of fluid resuscitation and the use of red blood cell transfusions are not yet clear in the context of brain injury...